{"title":"[科学出版物中的利益冲突及其可能的后果:以良性前列腺增生(BPH)为例的批判性分析]。","authors":"Jonas Herrmann, Christopher Netsch","doi":"10.1007/s00120-025-02550-4","DOIUrl":null,"url":null,"abstract":"<p><p>Technological advancements in endourology rely on close collaboration between medical expertise and industrial research. While this symbiosis is essential for medical progress, it also raises potential conflicts of interest. Using the treatment of benign prostatic hyperplasia (BPH) as an example, this study examines various mechanisms through which industry influences scientific evidence. These include selective study design, industry-sponsored educational events, and direct financial ties between industry and medical professionals. Case studies of Aquablation (ProCePT BioRobotics, San Jose CA, USA), Rezum (Boston Scientific, Marborough, MA, USA), and UroLift® (UroLift, Pleasanton, CA, USA) illustrate how methodological peculiarities in study designs and selective endpoint choices can impact the quality of evidence. The analysis underscores the need to balance technological innovation with the preservation of scientific independence. Proposed solutions include strengthening independent research funding, systematically incorporating patient preferences, and ensuring structured follow-up of long-term outcomes.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"352-357"},"PeriodicalIF":0.5000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Conflicts of interest in scientific publications and possible consequences : A critical analysis using the example of benign prostatic hyperplasia (BPH)].\",\"authors\":\"Jonas Herrmann, Christopher Netsch\",\"doi\":\"10.1007/s00120-025-02550-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Technological advancements in endourology rely on close collaboration between medical expertise and industrial research. While this symbiosis is essential for medical progress, it also raises potential conflicts of interest. Using the treatment of benign prostatic hyperplasia (BPH) as an example, this study examines various mechanisms through which industry influences scientific evidence. These include selective study design, industry-sponsored educational events, and direct financial ties between industry and medical professionals. Case studies of Aquablation (ProCePT BioRobotics, San Jose CA, USA), Rezum (Boston Scientific, Marborough, MA, USA), and UroLift® (UroLift, Pleasanton, CA, USA) illustrate how methodological peculiarities in study designs and selective endpoint choices can impact the quality of evidence. The analysis underscores the need to balance technological innovation with the preservation of scientific independence. Proposed solutions include strengthening independent research funding, systematically incorporating patient preferences, and ensuring structured follow-up of long-term outcomes.</p>\",\"PeriodicalId\":29782,\"journal\":{\"name\":\"Urologie\",\"volume\":\" \",\"pages\":\"352-357\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Urologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s00120-025-02550-4\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/3/10 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urologie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s00120-025-02550-4","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/10 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0
摘要
内分泌学的技术进步依赖于医学专业知识和工业研究之间的密切合作。虽然这种共生关系对医学进步至关重要,但它也引发了潜在的利益冲突。本研究以治疗良性前列腺增生(BPH)为例,探讨工业影响科学证据的各种机制。这些包括选择性研究设计、行业赞助的教育活动以及行业和医疗专业人员之间的直接财务联系。Aquablation (ProCePT BioRobotics, San Jose CA, USA)、Rezum (Boston Scientific, Marborough, MA, USA)和UroLift®(UroLift, Pleasanton, CA, USA)的案例研究说明了研究设计和选择性终点选择的方法学特性如何影响证据的质量。分析强调了平衡技术创新与维护科学独立性的必要性。建议的解决方案包括加强独立研究经费,系统地纳入患者偏好,并确保长期结果的结构化随访。
[Conflicts of interest in scientific publications and possible consequences : A critical analysis using the example of benign prostatic hyperplasia (BPH)].
Technological advancements in endourology rely on close collaboration between medical expertise and industrial research. While this symbiosis is essential for medical progress, it also raises potential conflicts of interest. Using the treatment of benign prostatic hyperplasia (BPH) as an example, this study examines various mechanisms through which industry influences scientific evidence. These include selective study design, industry-sponsored educational events, and direct financial ties between industry and medical professionals. Case studies of Aquablation (ProCePT BioRobotics, San Jose CA, USA), Rezum (Boston Scientific, Marborough, MA, USA), and UroLift® (UroLift, Pleasanton, CA, USA) illustrate how methodological peculiarities in study designs and selective endpoint choices can impact the quality of evidence. The analysis underscores the need to balance technological innovation with the preservation of scientific independence. Proposed solutions include strengthening independent research funding, systematically incorporating patient preferences, and ensuring structured follow-up of long-term outcomes.