International Journal of Pharma Medicine and Biological Sciences最新文献_第10页

A Collagen Formula for Anti-aging 抗衰老胶原蛋白配方

International Journal of Pharma Medicine and Biological Sciences Pub Date : 1900-01-01 DOI: 10.18178/ijpmbs.9.4.175-179

Shu-Ting Chang, Yung-Hsiang Lin, Chen-Meng Kuan, K. Kan, Yung-Kai Lin

引用次数: 0

Phycocyanobilin: A Potential Anticancer Therapy—A Tale of a Natural Chromophore 藻蓝胆素:一种潜在的抗癌疗法——一种天然发色团的故事

International Journal of Pharma Medicine and Biological Sciences Pub Date : 1900-01-01 DOI: 10.18178/ijpmbs.11.2.30-35

Suzan A. Rashed, A. Osman, S. Hammad, Moustafa M. Eldakak, Islam A Khalil

引用次数: 1

In-Silico Works on the Control of Blood Glucose Level for Type 1 Diabetes Mellitus (T1DM) Using Improved Hovorka Equations 利用改进的Hovorka方程控制1型糖尿病(T1DM)血糖水平的计算机研究

International Journal of Pharma Medicine and Biological Sciences Pub Date : 1900-01-01 DOI: 10.18178/ijpmbs.9.4.144-151

Ayub Md Som, N. Yusof, Sherif Abdulbari Ali, Nur’Amanina Mohd Sohadi, Amar, M. Maarof

{"title":"In-Silico Works on the Control of Blood Glucose Level for Type 1 Diabetes Mellitus (T1DM) Using Improved Hovorka Equations","authors":"Ayub Md Som, N. Yusof, Sherif Abdulbari Ali, Nur’Amanina Mohd Sohadi, Amar, M. Maarof","doi":"10.18178/ijpmbs.9.4.144-151","DOIUrl":"https://doi.org/10.18178/ijpmbs.9.4.144-151","url":null,"abstract":"—Artificial pancreas technology has been continuously developed over the past few years. However, there are still weaknesses found in recent technology in relation to injection of insulin subcutaneously into Type 1 Diabetes Mellitus (T1DM) patient. The injection of insulin into the patient’s body must be specific, exact and precise to ensure that the blood glucose level is between normoglycemic ranges, i.e. 4.5 mmol/L to 6.0 mmol/L so as to avoid hypoglycemia and hyperglycemia episodes. Therefore, this study aims to find the optimum insulin infusion rate into the patient’s body for the blood glucose level (BGL) to be maintained at a safe glycemic range. The study mainly focuses on computer simulation in MATLAB using improved Hovorka equations coupled with an enhanced model predictive control (eMPC) as its control scheme in order to control the BGL in T1DM. Only meal disturbance factor is included and it varies in carbohydrate (CHO) intake during breakfast, lunch and dinner times. The simulation was successfully carried out and its findings indicated that the safe glycemic range was able to be reached at shorter time and maintained for a prolonged period as compared to previous workers.","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"12 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129235566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Feasibility Study of a 1000+ Electrode Array in Epiretinal Prosthesis 1000+电极阵列用于视网膜外假体的可行性研究

International Journal of Pharma Medicine and Biological Sciences Pub Date : 1900-01-01 DOI: 10.18178/ijpmbs.5.3.163-170

Diego Lujan Villarreal, D. Schroeder, W. Krautschneider

{"title":"Feasibility Study of a 1000+ Electrode Array in Epiretinal Prosthesis","authors":"Diego Lujan Villarreal, D. Schroeder, W. Krautschneider","doi":"10.18178/ijpmbs.5.3.163-170","DOIUrl":"https://doi.org/10.18178/ijpmbs.5.3.163-170","url":null,"abstract":"To improve resolution and achieve functional vision, it is required 1000 electrodes with minimum feature size at epiretinal prosthetic devices. This challenging aim, however, has a limitation as to accommodate 1000+ electrode array and be within the limits of charge density and temperature increase at the device. In this work, we simulated a ganglion cell ON-model with PEDOT-NaPSS arranged electrode array in a three-dimensional retina model using COMSOL-Matlab interface. We varied electrode size, pulse width and inter electrode-ganglion cell distance to analyze charge density and temperature increase at the device. With our results, we investigated the feasibility of using 1024 electrode array attaching 16 scalable chips of 64 electrodes each with a daisy chain configuration. For IEGD less than 10 μm, it is feasible to use 1024 array of electrodes with the following requirements: i) reduce electrode diameter to 2μm; ii) maximum output voltage of 1 V; iii) work with either 50 or 100μs low pulse duration; iv) 11.3mm electrode carrier area; v) PEDOTNaPSS electrode deposition and vi) circular electrodes. ","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"576 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117062370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

EEG Processing System for Detecting a State of Drowsy Driving 检测疲劳驾驶状态的脑电图处理系统

International Journal of Pharma Medicine and Biological Sciences Pub Date : 1900-01-01 DOI: 10.18178/ijpmbs.5.3.154-157

M. Kedir-Talha, Sid Ahmed Walid Talha, Feriel Celia Boumghar, Karim Meddah, Hadjar Zairi

引用次数: 2

Wearable Care System for Elderly People 老年人穿戴式护理系统

International Journal of Pharma Medicine and Biological Sciences Pub Date : 1900-01-01 DOI: 10.18178/ijpmbs.5.3.171-177

M. Frydrysiak, Ł. Tęsiorowski

{"title":"Wearable Care System for Elderly People","authors":"M. Frydrysiak, Ł. Tęsiorowski","doi":"10.18178/ijpmbs.5.3.171-177","DOIUrl":"https://doi.org/10.18178/ijpmbs.5.3.171-177","url":null,"abstract":"A growing number of elderly persons in Poland and Europe forces us to looking for new solutions for the continuous monitoring of their health state. This approach allows for early action in case of dangerous situations for elderly person life (state before heart attack or stroke, etc.). The system for continuously monitoring the health state also allows for quick action of first contact doctors in the case of emergency situations. This described system also allows the remotely monitoring of elderly people in their home by their relatives. The monitoring system is portable, comfortable to use and uses non-invasive measurement methods. This kind of clothing is full user-friendly product. The textronic system is a new product for monitoring selected human physiological parameters, such as: pulse, frequency of breathing, underclothing temperature, positioning inside and outside the house. Textile sensory elements and signal lines are implemented in the structure of the clothing and it is a main innovation of this kind of systems. System of a textile sensor is part of a garment, the monitoring system is fully portable, easy for using, does not require specialized medical services. Furthermore, measurement of physiological parameters is non-invasive which means that does not interfere directly in the human body. The system is completely safe, because it is supplied by a miniature battery such as the one that are used in mobile phones. The combination of textile clothing interface with specialized software for data acquisition and generation of alarm signals provides a continuous overview of the health status of the monitored person.","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116945691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Apply Text Mining to Advance Cancer Research 应用文本挖掘来推进癌症研究

International Journal of Pharma Medicine and Biological Sciences Pub Date : 1900-01-01 DOI: 10.18178/ijpmbs.4.2.132-135

Si Yan, Y. Qi

引用次数: 3

Conductometric, Spectrophotometric and In vivo Investigation of the Interaction of Ca(II) Ion with Oxytetracycline Hydrochloride 电导、分光光度及体内研究钙离子与盐酸土霉素的相互作用

International Journal of Pharma Medicine and Biological Sciences Pub Date : 1900-01-01 DOI: 10.18178/ijpmbs.4.3.197-203

Elsayed T. Helmy, E. Gomaa, E. M. A. Elleef, A. Negm

{"title":"Conductometric, Spectrophotometric and In vivo Investigation of the Interaction of Ca(II) Ion with Oxytetracycline Hydrochloride","authors":"Elsayed T. Helmy, E. Gomaa, E. M. A. Elleef, A. Negm","doi":"10.18178/ijpmbs.4.3.197-203","DOIUrl":"https://doi.org/10.18178/ijpmbs.4.3.197-203","url":null,"abstract":"The interaction of antibiotic oxytetracycline hydrochloride (OTC) with calcium chloride has been investigated by conductometric, spectrophotometric and invivo, methods under equilibrium conditions. The interaction of OTC with calcium ion in water and in methanol solvents has been found to form two complexes 1:1 and 2:1 (metal to ligand molar ratio) conductometricallyand the values of Kf has been calculated from conductivity measurements at 293.15, 298.15, 303.15 and 308.15 K, Gibbs free energy of formation, enthalpy and entropy change of complexation were determined from the temperature dependence of the formation constant. Also Kf calculated from the absorption spectra of CaCl2 – OTC complexes in methanol solvent at 293.15 K indicates the formation of 2:1. In case of in-vivo studies there is no significant change was observed in the mean value of serum ionized calcium of the treated rats, this indicates that the values obtained from Conductometric and spectrophotometric studies are accepted because the stability constant values were found to be in biologically active range. All values are discussed. ","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123140835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Material Quantification Using Spectral Computed Tomography 使用光谱计算机断层扫描进行材料量化

International Journal of Pharma Medicine and Biological Sciences Pub Date : 1900-01-01 DOI: 10.18178/ijpmbs.4.2.80-84

R. Zainon, J. Ronaldson, A. Butler, P. Butler

引用次数: 0

Lower Ratio of Collagen’s Fibre Type III/Type I and Higher Tensile Strength in Injured Rabbit’s Achilles Tendon Treated with Astaxanthin 虾青素治疗兔跟腱损伤后III型/ I型胶原纤维比例降低，抗拉强度提高

International Journal of Pharma Medicine and Biological Sciences Pub Date : 1900-01-01 DOI: 10.18178/ijpmbs.5.2.121-124

K. Agus, Astawa Putu, Mulyadi Ridia K. G., Nindhia Tjokorda Gde Tirta

{"title":"Lower Ratio of Collagen’s Fibre Type III/Type I and Higher Tensile Strength in Injured Rabbit’s Achilles Tendon Treated with Astaxanthin","authors":"K. Agus, Astawa Putu, Mulyadi Ridia K. G., Nindhia Tjokorda Gde Tirta","doi":"10.18178/ijpmbs.5.2.121-124","DOIUrl":"https://doi.org/10.18178/ijpmbs.5.2.121-124","url":null,"abstract":"Tendon injuries vary from minor to total tear that requires surgery. The mechanical disturbance is the most complication. Inflammatory process and formation of free radicals can worsen tendon healing. Astaxanthin can be used to help tendon healing. This study aims to prove ratio of collagen type III/type I was lower and the tensile strength was higher on the administration of astaxanthin. This study is an experimental research using post-test only control group design with rabbit as subject. A total of 32 research subjects which meet inclusion were randomly divided into treatment and control groups. The treatment group is the group that was given astaxanthin after Achilles tendon was sharply cut and sewn, while the control group was not given astaxanthin. Statistical analysis using independent t-test found significant difference between treatment and control groups. The ratio of collagen type III/type I of the rabbit Achilles tendon which receive treatment of astaxanthin is smaller than the untreated group p = 0.000 (p<0.05). The tensile strength is greater in treatment group than the nontreated group with p = 0.044 (p<0.05). The result showed that the ratio of collagen type III/type I was lower when treated with astaxanthin thus can help improve the tensile strength.","PeriodicalId":281523,"journal":{"name":"International Journal of Pharma Medicine and Biological Sciences","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121336152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0