Feasibility Study of a 1000+ Electrode Array in Epiretinal Prosthesis

Diego Lujan Villarreal, D. Schroeder, W. Krautschneider
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引用次数: 6

Abstract

To improve resolution and achieve functional vision, it is required 1000 electrodes with minimum feature size at epiretinal prosthetic devices. This challenging aim, however, has a limitation as to accommodate 1000+ electrode array and be within the limits of charge density and temperature increase at the device. In this work, we simulated a ganglion cell ON-model with PEDOT-NaPSS arranged electrode array in a three-dimensional retina model using COMSOL-Matlab interface. We varied electrode size, pulse width and inter electrode-ganglion cell distance to analyze charge density and temperature increase at the device. With our results, we investigated the feasibility of using 1024 electrode array attaching 16 scalable chips of 64 electrodes each with a daisy chain configuration. For IEGD less than 10 μm, it is feasible to use 1024 array of electrodes with the following requirements: i) reduce electrode diameter to 2μm; ii) maximum output voltage of 1 V; iii) work with either 50 or 100μs low pulse duration; iv) 11.3mm electrode carrier area; v) PEDOTNaPSS electrode deposition and vi) circular electrodes. 
1000+电极阵列用于视网膜外假体的可行性研究
为了提高分辨率和实现功能性视觉,视网膜前假体装置需要1000个具有最小特征尺寸的电极。然而,这个具有挑战性的目标有一个限制,即容纳1000+电极阵列,并且在设备的电荷密度和温度升高范围内。本研究利用COMSOL-Matlab界面,利用PEDOT-NaPSS排列电极阵列在三维视网膜模型上模拟神经节细胞on模型。我们改变了电极尺寸、脉冲宽度和电极与神经节细胞之间的距离来分析器件的电荷密度和温度升高。根据我们的研究结果,我们研究了使用1024电极阵列连接16个可扩展芯片的可行性,每个芯片有64个电极,每个电极具有菊花链结构。对于小于10 μm的egd,采用1024阵列电极是可行的,但有以下要求:1)将电极直径减小到2μm;ii)最大输出电压为1v;Iii)低脉冲持续时间为50或100μs;Iv)电极载流子面积11.3mm;v) PEDOTNaPSS电极沉积和vi)圆形电极。
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