Chettinad Health City Medical Journal最新文献

{"title":"Revolutionising Medical Education: The Impact and Future of Technology","authors":"Raja D","doi":"10.24321/2278.2044.202342","DOIUrl":"https://doi.org/10.24321/2278.2044.202342","url":null,"abstract":"How to cite this article:Raja D. Revolutionising Medical Education: TheImpact and Future of Technology. ChettinadHealth City Med J. 2023;12(3):1-2.","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135127335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age and Gender-wise Distribution, Social History, and Length of Hospital Stay of Cardiovascular Patients with Drug-related Problems","authors":"Katike Mohammad Umar","doi":"10.24321/2278.2044.202323","DOIUrl":"https://doi.org/10.24321/2278.2044.202323","url":null,"abstract":"Introduction: A patient’s quality of life, mortality, and morbidity are all impacted by drug-related problems. These problems can occur at any stage of the prescription, transcription, distribution, and administration of medications. Research into the frequency, manifestations, patterns, and treatment implications of drug-related problems in cardiovascular patients will advance, leading to a rise in patient safety and recovery. Methods: A potential interventional trial was discussed over the course of 8 months in the cardiology and tertiary care medical departments. The required demographic and clinker data were acquired from the case files. Results: In this study, 246 cardiovascular patients were enrolled, and 1567 drug-related problems (DRPs) were found, with reference to the inclusion and exclusion conditions. Conclusion: In conclusion, population ageing and growth contribute to the global increase in CVD fatalities. Alcohol and tobacco use are linked to CVDs, with harmful effects observed at high consumption levels. Excessive alcohol and smoking increase blood pressure, cholesterol, and the risk of stroke and heart failure. However, moderate drinking poses minimal risks and may have some benefits. Efforts to reduce smoking and excessive drinking are essential for improving cardiovascular health and reducing CVD-related risks. How to cite this article:Umar KM, Latha CM. Age and Gender-wise Distribution, Social History, and Length of Hospital Stay of Cardiovascular Patients with Drug-related Problems. Chettinad Health City Med J. 2023;12(2):21-27. DOI: https://doi.org/10.24321/2278.2044.202323","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136366403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epigallo Catechin Gallate (EGCG) and Sorafenib: A Better Cytoprotective Agent in Diethyl Nitrosamine (DEN) Induced Liver Cancer – Anin Vivo Study","authors":"Dr. V Suganth","doi":"10.24321/2278.2044.202329","DOIUrl":"https://doi.org/10.24321/2278.2044.202329","url":null,"abstract":"Introduction: Carcinoma of the liver is the most frequently noticed malignant neoplasm of the liver and it occupies the third position in cancer-related deaths. Epicatechin-3-gallate, Epigallocatechin-3-gallate, abbreviated as EGCG, constitutes about 50-75% of the catechins. Administration of EGCG inhibits the proliferation of cancerous cells and encourages cell death (apoptosis). Sorafenib is an oral multikinase inhibitor that exerts its inhibitory effects on tumours through angiogenesis inhibition. So, the present study was undertaken to analyse the beneficial effects of naturally occurring agents, EGCG and sorafenib, on carcinoma of the liver. Materials and Methods: 40 adult male Wistar albino rats were procured and divided into five equal groups. Control animals were in Group 1 and negative controls were in Group 2 Sorafenib treatment was given to Group 3 and EGCG alone was given to Group 4 Group 5 received both sorafenib and EGCG. Results: We have found that the combined treatment group of EGCG and sorafenib had low levels of AFP, increased levels of mitochondrial enzymes, Phase II enzymes and showed a decrease in enzymes of Phase I and a fall in glycoprotein components level. Conclusion: Epigallocatechin-gallate (EGCG) when given with sorafenib has shown enhanced cytoprotective effects. How to cite this article:Neelamegam U, Suganthi V, Muthuvel R. Epigallo Catechin Gallate (EGCG) and Sorafenib: A Better Cytoprotective Agent in Diethyl Nitrosamine (DEN) Induced Liver Cancer – An in Vivo Study. Chettinad Health City Med J. 2023;12(2):63-70. DOI: https://doi.org/10.24321/2278.2044.202329","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136367379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementing Pharmacovigilance at Bathalapalli Hospital to Monitor Adverse Drug Reactions and Improve Patient Care","authors":"Kommanuru Venkata Ramakrishna Teja","doi":"10.24321/2278.2044.202331","DOIUrl":"https://doi.org/10.24321/2278.2044.202331","url":null,"abstract":"Introduction: Although adverse drug reaction (ADR) monitoring is widely known, it is not practised in underdeveloped nations due to a lack of awareness and the absence of a central coordinating agency. The recent implementation of the National Pharmacovigilance Programme has encouraged ADR monitoring in some centres. Methods: The purpose of this study was to evaluate the sternness of described ADRs, the additional financial costs associated with ADRs, and the present load of ADRs at a Rural Development Trust (RDT) Hospital in Bathalapalli, Andhra Pradesh, India. The study was carried out over 26 months of inpatient admissions to the medical wards. Results: 37 of the 74 adverse drug events (ADEs) that were reported by 56 individuals were indeed ADRs. There were 521 patients admitted, and 9.7% of those ADRs occurred during hospitalisation. Males (56%) had ADRs more often than females (44%). During the hospital stay, no discernible difference between males and females was seen. ADR rates were 19.0%, 20.0%, and 61.0 % for paediatric, geriatric, and adult patients, respectively. Based on ADR severity, more than half of the reported reactions (76.49%) were in the moderate category, followed by mild (13.51%) and severe (10%) categories. 39.6% of patients recovered from the incident. The majority of the responses showed that the ADRs were unexpected and possibly avoidable. Conclusion: According to the study’s findings, 90% of ADRs might be prevented, saving the health system money and decreasing patient expenditures. To prevent unknown and severe ADRs, new medications should be continuously monitored.","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"211 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136368310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Content Validation of Perceived Barriers to Exercise Questionnaire (PBEQ-I) for Indian Office Workers","authors":"Sougata Panda","doi":"10.24321/2278.2044.202325","DOIUrl":"https://doi.org/10.24321/2278.2044.202325","url":null,"abstract":"Background: Physical inactivity worldwide is a major challenge in preventing various non-communicable diseases. In India, physical inactivity is observed in the average population, mostly in office workers involved with sitting or clerical jobs. Studies showed that there are different barriers, facilitators, and preferences for exercises that already exist for office workers. To our knowledge, no questionnaire currently addresses perceived barriers to exercise among Indian office workers. Objective: To measure self-reported perceived barriers to exercise for the employees working in the office. Methodology: This study has two essential components: domain and item development and content validation using the online Delphi method. The questionnaire was validated using the Content Validity Index (CVI) and modified Kappa, the most used quantitative method for calculating content validity. The questionnaire was validated by a panel of 13 experts in two rounds of validation. Results: The initial testing revealed low content validity for individual items (I-CVI range: 0.50 to 1.00) and moderate agreement (Kappa range: 0.27 to 1). After modifying and replacing items, the second round achieved acceptable scores (CVI: 0.85-1 and Kappa: 0.84-1). The final instrument had five domains and twenty-five questions. The domains were as follows: (1) personal barrier; (2) professional barrier; (3) social and family barrier; (4) preferences; and (5) knowledge barrier domain. Conclusions: Using an iterative methodology, the validation of the perceived barriers to exercise questionnaire (PBEQ-I) for Indian office workers revealed a high level of item-content validity for assessing the perceived barriers to exercise among office employees. Further reliability testing is required to validate this instrument’s psychometric qualities. How to cite this article:Panda S, Singh A, Bali3 S, Bhargava A. Development and Content Validation of Perceived Barriers to Exercise Questionnaire (PBEQ-I) for Indian Office Workers. Chettinad Health City Med J. 2023;12(2):33-40. DOI: https://doi.org/10.24321/2278.2044.202325","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136368312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Emotional Stress and Physiotherapy Treatment on Prognosis of Temporomandibular Joint Disc Displacement with Reduction - A Case Report","authors":"Vinotha Durai","doi":"10.24321/2278.2044.202339","DOIUrl":"https://doi.org/10.24321/2278.2044.202339","url":null,"abstract":"Many conservative treatment approaches are used for patients with temporomandibular joint disorders (TMD). Nonetheless, only a few studies have been published about physiotherapy treatment for patients with temporomandibular joint disc anterior displacement with reduction. A few studies have emphasised the relationship between increasing emotional stress and the occurrence of TMD. This report aimed to study the impact of integrated physiotherapy treatment (ultrasound therapy, soft tissue mobilisation, manual therapy and exercise therapy) approach for patients with temporomandibular joint disc displacement with reduction. The initial hypothesis of this study was that integrated physiotherapy treatment will reduce the patient’s symptoms and improve the quality of life. The outcome measures of our report showed that integrated physiotherapy treatment reduced the patient’s symptoms for a short period of time (3 weeks) post-treatment but was not effective in the long term. Even-though, the patient had followed all the self-management strategies, the patient was not able to cope with increasing emotional stress from day-to-day life which resulted in aggravation of the clinical condition. Our report concludes that the psychological aspect of the clinical condition must be included during the evaluation and treatment of patients with TMD for better treatment prognosis. How to cite this article:Durai V, Thiyagarajan A. Impact of Emotional Stress and Physiotherapy Treatment on Prognosis of Temporomandibular Joint Disc Displacement with Reduction - A Case Report. Chettinad Health City Med J. 2023;12(2):117-121. DOI: https://doi.org/10.24321/2278.2044.202339","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"211 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136368320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Analysis of Diagnostic Imaging in Acute Ischaemic Stroke","authors":"Dupinder Kaur","doi":"10.24321/2278.2044.202320","DOIUrl":"https://doi.org/10.24321/2278.2044.202320","url":null,"abstract":"Introduction: Acute ischaemic stroke (AIS) is responsible for almost 90% of all strokes. Large vessel occlusion is mainly responsible for AIS. Earlier treatment of AIS is associated with improved outcomes. Multimodal imaging methods such as MRI and CT provide information that can help in diagnosing it. These methods are helpful in the prognosis of AIS and in the selection of patients who can be subjected to thrombolytic therapy. Objectives of the Study: The present comparative study has been conducted to understand whether MRI images are better for the diagnosis of AIS than CT, to assess the efficacy of tPA in the recovery of patients, and to explore the role of advanced imaging in acute stroke. Methods: The present study was conducted with 40 patients, aged 18 years and above who presented to the Emergency Department of Uppal Neuro Hospital, Amritsar, Punjab with a history of acute ischaemic stroke or hyperacute stroke between September 2017 and March 2018. All patients were examined using 32 slices CT and 1.5T MRI scanner. Among all cases, 17 patients had suffered a hyperacute stroke and 23 had suffered an acute ischaemic stroke. Conclusion: Sophisticated techniques such as perfusion imaging and non-invasive vascular imaging are becoming more effective tools for guiding prospective endovascular treatment or extending therapy windows in the case of patients with acute ischaemic stroke. How to cite this article: Kaur D, Bansal RP, Uppal A. A Comparative Analysis of Diagnostic Imaging in Acute Ischaemic Stroke. Chettinad Health City Med J. 2023;12(2):3-8. DOI: https://doi.org/10.24321/2278.2044.202320","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136366153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rabies: India’s Current Burden - Are We Winning the Battle?","authors":"Rijoe Rajulin","doi":"10.24321/2278.2044.202341","DOIUrl":"https://doi.org/10.24321/2278.2044.202341","url":null,"abstract":"How to cite this article:Rajulin R, Rathinasamy M. Rabies: India’s Current Burden - Are We Winning the Battle? Chettinad Health City Med J. 2023;12(2):125-126. DOI: https://doi.org/10.24321/2278.2044.202341","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136366382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Ethanolic Extracts for Two Plants on Wound Healing in Diabetic Albino Rats","authors":"Girish Kumar Vyas","doi":"10.24321/2278.2044.202327","DOIUrl":"https://doi.org/10.24321/2278.2044.202327","url":null,"abstract":"Background: Wounds in diabetic patients are critical to treat. The use of allopathic drugs has various side effects, hence new natural sources for therapies are vital. Materials and Methods: This research aimed to determine the possibility of wound healing by the ethanolic extract of Eucalyptus globulus leaves and Curcuma longa rhizomes. Albino rats were given oral administration of various plant extracts in order to find out how plant extracts affected diabetic rats’ wound healing. Results: These plant extracts greatly accelerated the wound’s ability to heal in diabetic or non-diabetic rats (p < 0.05). This increases the proliferation and migration of the fibroblast resulting in a faster healing process. These plant extracts do not cause cytotoxicity. After treatment, less amount of cell death was found for both plant extracts. The results were found to be positive. Conclusion: This research indicates that the ethanolic extracts of both plants have the potential to be used as novel therapeutics for diabetic patients’ wound healing. How to cite this article:Vyas GK, Sharma H, Vyas B, Sharma A, Sharma M. Efficacy of Ethanolic Extracts for Two Plants on Wound Healing in Diabetic Albino Rats. Chettinad Health City Med J. 2023;12(2):46-55. DOI: https://doi.org/10.24321/2278.2044.202327 &nbsp","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136366384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude and Misconception Regarding Organ Donation among General Population","authors":"Neethu Jose","doi":"10.24321/2278.2044.202332","DOIUrl":"https://doi.org/10.24321/2278.2044.202332","url":null,"abstract":"Introduction: Transplanting organs and tissues has become a crucial component of healthcare worldwide. Therefore, it has become imperative to increase public awareness of and attitudes regarding organ donation. Objectives: (i) To ascertain the general understanding of the public regarding organ donation, (ii) To determine how the general public feels about organ donation, (iii) To determine the widespread misconceptions that discourage people from volunteering for organ donation. Methodology: A descriptive cross-sectional questionnaire survey was designed for 100 participants from the general population in Kerala. Results: Overall, 97% of study participants knew something about organ donation and 97% of people expressed support for organ donation. The majority of participants were aware of the laws governing organ donation and its procedure. This study highlights the significance of increasing public knowledge to remove barriers and disbeliefs that keep people from volunteering for organ donation. Conclusion: Knowledge and misconception were found to be interrelated with the general public’s attitude towards their willingness to organ donation. Knowledge about the concept of brain death and transplant procedure may help in increasing the rate of willingness towards organ donation. How to cite this article:Jose N, Joseph JK, Sebastian S. Knowledge, Attitude and Misconception Regarding Organ Donation among General Population. Chettinad Health City Med J. 2023;12(2):83-87. DOI: https://doi.org/10.24321/2278.2044.202332","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136367383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}