Proceedings of the 7th World Congress on Recent Advances in Nanotechnology最新文献_第2页

Green Synthesis, Mechanism, & Intrinsic Properties of Kraft Lignin Nanoparticles 硫酸盐木质素纳米颗粒的绿色合成、机理及特性研究

Proceedings of the 7th World Congress on Recent Advances in Nanotechnology Pub Date : 2022-04-01 DOI: 10.11159/icnnfc22.166

Ahilan Manisekaran, P. Grysan, B. Duez, D. Lenoble, J. Thomann

{"title":"Green Synthesis, Mechanism, & Intrinsic Properties of Kraft Lignin Nanoparticles","authors":"Ahilan Manisekaran, P. Grysan, B. Duez, D. Lenoble, J. Thomann","doi":"10.11159/icnnfc22.166","DOIUrl":"https://doi.org/10.11159/icnnfc22.166","url":null,"abstract":"Extended Abstract Lack of petroleum resources and sustainability concerns have led researchers to find green alternatives, such as Kraft Lignin (KL). KL is economical, eco-friendly, abundantly available, and usually obtained as a by-product from paper industries. KL is well known for its wide range of versatile applications such as, UV-absorber, antioxidant, anti-microbial, binder, dispersant, fillers, polymer, surfactant, a source of carbon and phenol, drug carrier, green composite, and 3D printing. [1] Due to its recent demand, scientists are synthesizing nanoparticles out of KL. Solvent shifting is the greenest method to synthesize Kraft Lignin Nanoparticles (KLNPs). State of the art: Lignin is dissolved in a solvent, then the lignin solution is mixed with an excess amount of non-solvent. The formation of the nanoparticles takes place immediately due to the self-assembly of lignin. The secondary valency forces such as intermolecular π-π stacking, H-bonding, and van der Waals forces of lignin drive the self-assembly. The identification and understanding of all the synthesis parameters behind the solvent-shifting is the gap in the literature. We identified five","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125819922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Indocyanine Green-Loaded Ferritin Nanoparticles for Intraoperative Detection of Cancer Tissue 吲哚菁绿色负载铁蛋白纳米颗粒在术中检测肿瘤组织中的应用

Proceedings of the 7th World Congress on Recent Advances in Nanotechnology Pub Date : 2022-04-01 DOI: 10.11159/nddte22.142

M. Sevieri, S. Mazzucchelli, Arianna Chesi, C. Sottani, F. Corsi

{"title":"Indocyanine Green-Loaded Ferritin Nanoparticles for Intraoperative Detection of Cancer Tissue","authors":"M. Sevieri, S. Mazzucchelli, Arianna Chesi, C. Sottani, F. Corsi","doi":"10.11159/nddte22.142","DOIUrl":"https://doi.org/10.11159/nddte22.142","url":null,"abstract":"Extended Abstract Background: Nanotechnology represents one of the most promising field of study in this century, considering that its application to medicine is becoming fundamental in the diagnosis and treatment of several diseases such as cancer. Since chemotherapy often suffers from limited effectiveness and specificity against cancer cells, causing important side effects and toxicity in healthy tissues, the main clinical option is still usually represented by surgery. In this context, the development of nano-tracers with tumor specificity to achieve an accurate and timely diagnosis could be of crucial importance. In recent years, several studies have been carried out using nanoparticles of ferritin (HFn), that offer new therapeutic options, potentially allowing the specific drug delivery to cancer cells, as well as the possibility of exploiting them as nano-tracers for tumor detection and fluorescence-guided surgery (FGS) applications. Indeed, one of the most important features of HFn is its natural homing towards cancer cells thanks to the specific recognition of the transferrin-1 receptor (TfR1), which is abundantly expressed in most tumor subtypes [1-4]. Objectives: To support surgeons during intraoperative tumor and metastasis localization, we proposed the use of ferritin nanoparticles","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133011147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanoscale Antimycotics and Antifungal Active Nanocomposites 纳米抗真菌药物和抗真菌活性纳米复合材料

Proceedings of the 7th World Congress on Recent Advances in Nanotechnology Pub Date : 2022-04-01 DOI: 10.11159/nddte22.001

J. Jampílek

{"title":"Nanoscale Antimycotics and Antifungal Active Nanocomposites","authors":"J. Jampílek","doi":"10.11159/nddte22.001","DOIUrl":"https://doi.org/10.11159/nddte22.001","url":null,"abstract":"Extended Abstract Fungi are simple eukaryotic organisms that are able to colonize various environments. It is estimated that there are approx. 2 million different species. Fungi have been used by people in the kitchen, brewing, viticulture, folk medicine as well as in biotechnology for the production or biotransformation of various substances and in recent years are also popular for the green synthesis of nanoparticles. Biologically active secondary metabolites of fungi have become the inspiration for the design of drug structures [1,2]. Fungi are ubiquitous in nature and are vital for the recycling of nutrients contained in organic matter (most species of fungi are saprophytes). They coexist with other organisms on the basis of mutualism, commensalism, and unfortunately parasitism [3,4]. Some fungi attack humans, animals and plants; it is estimated that 270,000 species of fungi are associated with plants and 325 are known to infect humans. Fungi cause diseases ranging from superficial and cutaneous forms through complicated subcutaneous forms to systemic (invasive fungal infections) diseases. Mycoses are caused by colonization/proliferation/sporulation of fungi in tissues and body fluids. Another type of body damage with various clinical symptoms is caused by mycotoxins, which can be ingested in the diet or secreted by fungi in the body [3-5]. It is about a people from The severity ranges from asymptomatic to mild mucocutaneous infections to life-threatening systemic infections. Approximately 10 million people have mucosal candidiasis and more than 150 million people serious fungal diseases","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121168749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanobody Based Nanosystems to Contend Neisseria meningitidis and West Nile Virus 基于纳米体的纳米系统对抗脑膜炎奈瑟菌和西尼罗病毒

Proceedings of the 7th World Congress on Recent Advances in Nanotechnology Pub Date : 2022-04-01 DOI: 10.11159/nddte22.103

Amod Kulkarni, Jana Hruškovicová, K. Bhide, Patrícia Mertinková, Evelína Mochnáčová, M. Bhide

引用次数: 0

New Consideration in Achievement of (Bio) Colloid Nanocomposites 制备(生物)胶体纳米复合材料的新思路

Proceedings of the 7th World Congress on Recent Advances in Nanotechnology Pub Date : 2022-04-01 DOI: 10.11159/icnnfc22.176

Railean-Plugaru Viorica, A. Król-Górniak, Pomastowski Paweł, Buszewski Boguslaw

{"title":"New Consideration in Achievement of (Bio) Colloid Nanocomposites","authors":"Railean-Plugaru Viorica, A. Król-Górniak, Pomastowski Paweł, Buszewski Boguslaw","doi":"10.11159/icnnfc22.176","DOIUrl":"https://doi.org/10.11159/icnnfc22.176","url":null,"abstract":"Extended Abstract In recent years, nanotechnology has become a part of almost every field of science (e. g. physics chemistry, biology, engineering etc.) allowing us to live a better and easier life. Nanotechnology is required for the measuring, monitoring, assembling and mediating at Nano scale by involving interdisciplinary approach for the structure, composition and stability characterization as well as medical area application [1]. On the other hand, sustainable development is attracting more attention and certainly, the pursuit of new opportunities to involve the resulting products (by-products) in the recycling process has developed high interest. Once the ecological problems are continuously increasing, giving a new life application of the resulting products (e.g. whey – after milk processing) has become a requirement. In fact, both milk as well as whey are a source of healthy nutrients and microorganisms aimed to contribute directly or indirectly to human life. In addition to that, many study including our works have been demonstrated firstly, the possibility to use the available whey as a cheap by-product source for the isolation of the safe lactic acids bacterial strains (LAB) and secondly, the involving of the respective strains in the nanocomposites (NCs) mediations (AgNPs, ZnONPs, etc.) [2, 3]. Therefore, the present study has proposed to attend several goals; (i) firstly, to promote the recycling approach by using LAB","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"509 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115892509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alginic Aldehyde-Gelatin Nanogel as Sustainable Drug Delivery System of Azithromycin: Development, Characterization and In Vitro Evaluation 海藻酸醛-明胶纳米凝胶作为阿奇霉素可持续给药体系:开发、表征及体外评价

Proceedings of the 7th World Congress on Recent Advances in Nanotechnology Pub Date : 2022-04-01 DOI: 10.11159/nddte22.108

Samin A. Dastjerd, Melike Sessevmez, Erdal Cevherand Gülhayat Nasun-Saygılı

{"title":"Alginic Aldehyde-Gelatin Nanogel as Sustainable Drug Delivery System of Azithromycin: Development, Characterization and In Vitro Evaluation","authors":"Samin A. Dastjerd, Melike Sessevmez, Erdal Cevherand Gülhayat Nasun-Saygılı","doi":"10.11159/nddte22.108","DOIUrl":"https://doi.org/10.11159/nddte22.108","url":null,"abstract":"- The present study deals with the encapsulation of Azithromycin in alginic aldehyde and gelatin nanogel as an intestinal site-specific and controlled therapeutic delivery system against gram-negative intracellular Salmonella Typhi, which is synthesized through inverse miniemulsion technique in three different drug to polymer ratios, and exploration the physicochemical properties and antibacterial activity of the system. The characterizations of the azithromycin-loaded nanogel were done by DLS and FT-IR. The hydrodynamic diameter of the azithromycin-loaded nanogel is 118±4 nm with negative zeta potential (-34.2±1.5 mV). We observed absolute transition from the crystalline form of the azithromycin to amorphous state while was loaded to the AA-Gel nanogel by FT-IR, and the FT-IR measurements demonstrate that there are not any detectable chemical and intramolecular interactions between AZM and nanogel network. The encapsulation efficiency of the loaded nanogels were influenced by the ratio of drug to polymer, which the highest value (86.3±2.3%) was demonstrated for the 1:3 formulation. In vitro azithromycin release profile from AA-Gel nanogels presents an initial burst release over a period of 4 hours that is followed by controlled release until the 24 hours. Nanogels showed significant bacteriostatic activities in comparison to free azithromycin. Our results indicate proper physicochemical, in vitro and ex vivo features of the azithromycin nanogel, which can be a worthy candidate for oral administration against Salmonella Typhi.","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121982985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and Evaluation of Nanocarrier Embedded Hybrid Hydrogels for Topical Delivery of Hydrophobic Molecules 纳米载体嵌入杂化水凝胶局部递送疏水分子的设计与评价

Proceedings of the 7th World Congress on Recent Advances in Nanotechnology Pub Date : 2022-04-01 DOI: 10.11159/nddte22.119

Reatul Karim, F. Rizwan, M. Tanim, Sabrin Islam Khan

{"title":"Design and Evaluation of Nanocarrier Embedded Hybrid Hydrogels for Topical Delivery of Hydrophobic Molecules","authors":"Reatul Karim, F. Rizwan, M. Tanim, Sabrin Islam Khan","doi":"10.11159/nddte22.119","DOIUrl":"https://doi.org/10.11159/nddte22.119","url":null,"abstract":"Menopause is a substantial event in women’s life as it significantly impacts their physiological and psychological wellbeing. As menopause commences, oestrogen and progesterone hormone productions are greatly reduced due to ovarian follicle depletion, resulting diverse symptoms e.g. vasomotor symptoms (hot flashes, osteoporosis), psychological symptoms (anxiousness, depression, excitation, irritability, mood swings), and physical symptoms (fatigue, insomnia, vertigo, tachycardia, weight gain, muscle & joint ache, breathing problem, vaginal dryness, bladder control problem) [1, 2]. Despite 2- to 4-folds higher chance of having clinical symptoms [3], which reduces quality of life in many women [4], hormone-replacement therapy (HRT) for postmenopausal women are often neglected, especially in developing countries like Bangladesh. Until now, no HRT formulations are produced locally or imported despite having over 80 million women population and well-established local pharmaceutical companies (which exports medicines to many European countries). The typical HRT in menopause is oestradiol (E2). There are many E2 formulations available worldwide for HRT, chiefly as hydrogels or as transdermal patches. The hydrogels between immediate release hydrogels and sustained release patches.","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125483800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Responsive Nanoparticles for Triggered Delivery of Anti-scar Drug to the Burn Wound 用于触发抗疤痕药物递送到烧伤创面的反应性纳米颗粒

Proceedings of the 7th World Congress on Recent Advances in Nanotechnology Pub Date : 2022-04-01 DOI: 10.11159/icnnfc22.135

F. J. Shariatzadeh, S. Logsetty, Song Liu

引用次数: 0

Cellulose Nanocrystals as a Versatile Platform for Regulation of Myeloid Cell Immunogenicity 纤维素纳米晶体作为髓细胞免疫原性调控的通用平台

Proceedings of the 7th World Congress on Recent Advances in Nanotechnology Pub Date : 2022-04-01 DOI: 10.11159/nddte22.149

S. Tomić, M. Bekić, M. Vasiljević, D. Stojanović, D. Vučević, P. Uskoković, M. Čolić, V. Kokol

引用次数: 0

Comparing in vitro Permeability of a Nanocarrier-Hydrogel Hybrid System with an Alcoholic Hydrogel for Sustained Transdermal Drug Delivery 比较纳米载体-水凝胶混合系统与酒精水凝胶持续经皮给药的体外渗透性

Proceedings of the 7th World Congress on Recent Advances in Nanotechnology Pub Date : 2022-04-01 DOI: 10.11159/nddte22.132

Reatul Karim, F. Rizwan, M. Tanim, Sabrin Islam Khan

{"title":"Comparing in vitro Permeability of a Nanocarrier-Hydrogel Hybrid System with an Alcoholic Hydrogel for Sustained Transdermal Drug Delivery","authors":"Reatul Karim, F. Rizwan, M. Tanim, Sabrin Islam Khan","doi":"10.11159/nddte22.132","DOIUrl":"https://doi.org/10.11159/nddte22.132","url":null,"abstract":"– Nanocarriers are commonly used as various types of drug delivery systems. However, the topical application of aqueous dispersions of nanocarriers is limited due to high fluidity of the formulations. In contrast, the topical application of various types of hydrogels are common for the good consistency and spreadability properties. For example, most marketed topical preparations of oestradiol (E2), which are used as hormone replacement therapy in menopausal women, are alcoholic hydrogels. Though, such formulations must be applied daily and chronic usage of alcohol can be damaging to the skin. In this paper, a lipid nanocapsule (LNC)-hydrogel hybrid system containing E2 was developed without the use of any alcohol or other organic solvents with an aim to achieve sustained transdermal drug delivery. In the LNCs, more than 95% of the drug was encapsulated and the dispersion was used to prepare a hydrogel using carboxypolymethylene. Moreover, an alcoholic hydrogel containing E2 was formulated to compare the in vitro transdermal E2 permeability using synthetic model STRAT-M®. Additionally, an apparatus for the permeability study was developed by modifying USP dissolution apparatus-I and its suitability was realized by comparing its results with the permeability in Franz diffusion cell apparatus. The LNC-hydrogel hybrid system showed more stable and sustained delivery of E2 compared to the alcoholic hydrogels. Therefore, the E2-LNC-hydrogel hybrid system can be a promising formulation for hormone replacement therapy in menopausal women with the potential to increase dosing intervals, reduce hormone label fluctuations by its more stable flux, and eliminate the damaging effects of chronic alcohol application on the skin.","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115550728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0