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Estimation of flavonoids and tannins extracted from medicinal plants on gentamicin-induced nephrotoxicity in local Iraqi rabbits 药用植物黄酮类和单宁提取物对庆大霉素致伊拉克家兔肾毒性的影响

Science Archives Pub Date : 1900-01-01 DOI: 10.47587/sa.2022.3309

Nuha Ali Hadi

{"title":"Estimation of flavonoids and tannins extracted from medicinal plants on gentamicin-induced nephrotoxicity in local Iraqi rabbits","authors":"Nuha Ali Hadi","doi":"10.47587/sa.2022.3309","DOIUrl":"https://doi.org/10.47587/sa.2022.3309","url":null,"abstract":"The present study aimed to find out the effect The study aimed to extract flavonoids and tannin from sumac, myrtle, and on domestic rabbits exposed to nephrotoxicity with gentamicin. the percentage of flavonoids recorded from myrtle and Sumac is 13.8%, and 12.7%, respectively. The percentage of tannin recorded from myrtle and Sumac is 15.9 %, and 12.7%, respectively. The study was conducted inside the body of the organism and nephrotoxicity was developed with gentamicin by injecting animals 80 mg/ml/day (IP) for two weeks, after which I was dosed orally with the Flavonoid extract of sumac and myrtle and tannin extract of sumac and myrtle for a month at a rate of 1 ml/kg/day. A significant increase in the group’s dose was found with gentamicin. An increase of 0.05 compared to the healthy control group. As well as a significant decrease of 0.05 for the groups treated with extracts compared to the control group for urea and creatinine. The total protein showed a significant increase of 0.05 for the group administered with gentamicin compared with the healthy control group and a significant decrease for the groups fed with extracts compared to the control group treated with gentamicin. As for albumin, a significant decrease was recorded for the group treated with gentamicin compared to the healthy control group by 0.05, and a significant increase for the groups treated with plant extracts compared with the control group treated with gentamicin. Uric acid showed a significant decrease in the groups treated with gentamicin compared with the healthy control group.","PeriodicalId":273863,"journal":{"name":"Science Archives","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130282047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Production of unsaturated fatty acids (omega 3,6,7,9) from algae Lyngbya and Oedogonium under the influence of nitrogen and phosphorus 在氮和磷的影响下，lyngyya和Oedogonium产生不饱和脂肪酸(omega 3,6,7,9)

Science Archives Pub Date : 1900-01-01 DOI: 10.47587/sa.2023.4216

Zahra M Abed al-Kathem, Roaa J Elkheralla

{"title":"Production of unsaturated fatty acids (omega 3,6,7,9) from algae Lyngbya and Oedogonium under the influence of nitrogen and phosphorus","authors":"Zahra M Abed al-Kathem, Roaa J Elkheralla","doi":"10.47587/sa.2023.4216","DOIUrl":"https://doi.org/10.47587/sa.2023.4216","url":null,"abstract":"Microalgae have a lot of promise for making nutritious food and feed additives. These photosynthetic show promise for the longterm production of lipids due to their capacity to transform carbon into high-value chemicals and their ability to be grown on a vast scale without interfering with crop cultivation. Particularly, microalgae serve as a substitute source of unsaturated fatty acids (UFAs), whose consumption is linked to a number of advantages for both human and animal health. The generation of PUFAs in microalgae has been improved in recent years through the investigation of several methods. Two algae were isolated from the Gharaf river in Thi-Qar (Oedogonium, Lyngbya). The study was conducted on the effect of different concentrations of nitrogen and phosphorus for each of the unsaturated fatty acids of the two algae. Nitrogen concentrations were (5,10,20) and for phosphorus (1,5,10). These (UFAs) are affected when these nutrients are added to the culture medium, and as the concentration of these nutrients increases, we notice a decrease in the proportions of these unsaturated fatty acids (Octadecatrienoic acid, omega 6, Oleic acid omega 9, Eicosapentanoic acid omega 3, Docosatetraenoic acid omega 3) in Lyngbya and with absence OA, Docosatetraenoic acid and presence (vaccenic acid, omega 7) in Oedogonium.","PeriodicalId":273863,"journal":{"name":"Science Archives","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129513534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of COVID-19 on c-reactive protein and d-dimer COVID-19对c反应蛋白和d-二聚体的影响

Science Archives Pub Date : 1900-01-01 DOI: 10.47587/sa.2021.2304

W. Mahdi, A. Atiyah

引用次数: 0

Metanil yellow suppresses contraction mediated ejection functions of heart ventricular muscle by inducing fibrillar and mitochondrial oxidative stress metail黄通过诱导纤维和线粒体氧化应激抑制收缩介导的心室肌射血功能

Science Archives Pub Date : 1900-01-01 DOI: 10.47587/sa.2022.3306

A. Biswas, D. Roy, Mousumi Dutta, G. Paul

{"title":"Metanil yellow suppresses contraction mediated ejection functions of heart ventricular muscle by inducing fibrillar and mitochondrial oxidative stress","authors":"A. Biswas, D. Roy, Mousumi Dutta, G. Paul","doi":"10.47587/sa.2022.3306","DOIUrl":"https://doi.org/10.47587/sa.2022.3306","url":null,"abstract":"The presence of metanil yellow (MY), a synthetic azo-dye, has been scientifically proved in different food products. It is mostly used in unorganized food industries as a food colorant due to its cost-effectiveness. Humans are often exposed to MY through ingested food products, colored with MY. The toxic effects of MY have already been reported in animal models. Till date, the effects of MY on heart ventricular functions have not been reported. So, our study was aimed to evaluate the effects of MY on the functions of heart ventricular muscle in rat model in vivo. We have observed significant (P<0.05) increase in the level of malondialdehyde and content of reduced glutathione in heart ventricular muscle of MY exposed groups of rats in comparison with control rats. The enzymatic activities of cytosolic copper-zinc-superoxide dismutase, glutathione peroxidase, glutathione reductase; and mitochondrial manganese superoxide dismutase and ATPase were significantly (P<0.05) increased in exposed groups. Whereas the activities of cytosolic catalase and acetylcholinesterase; mitochondrial catalase, Krebs cycle and electron transport chain enzymes were decreased significantly (P<0.05). Furthermore, myodegeneration of heart ventricular muscle and myofibrillar mitochondria of exposed rats have been identified through prominent signs of lesions and disintegrations by scanning electron microscopic and histological studies. So, from our observations we can conclude that MY depresses the contraction mediated ejection functions of heart, probably by inducing fibrillar and mitochondrial oxidative stress in heart ventricular muscle. The results obtained through this study in rat model could be extrapolated in humans.","PeriodicalId":273863,"journal":{"name":"Science Archives","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122274341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Applied successful therapeutic protocol for COVID-19 in Arab Homeland 在阿拉伯家园成功应用COVID-19治疗方案

Science Archives Pub Date : 1900-01-01 DOI: 10.47587/sa.2021.2212

M. Mahmood, Zenab Ghanim Younus Al-Ameen, Aras Fathi Al-Barazanchi, Taghreed Alkhanchi

引用次数: 2

Monobactams as anticancer : a review study 单巴克坦作为抗癌药物的研究综述

Science Archives Pub Date : 1900-01-01 DOI: 10.47587/sa.2022.3101

Ahmed A. J. Mahmood

引用次数: 0

Some factors affecting the yield and quality of banana: A Review 影响香蕉产量和品质的若干因素综述

Science Archives Pub Date : 1900-01-01 DOI: 10.47587/sa.2021.2309

Nofal O. A, R. A.