Effect of COVID-19 on c-reactive protein and d-dimer

Abstract

Since December 2019, the International Committee on Taxonomy of Viruses (ICTV) has formally designated a novel human coronavirus found in Wuhan, China, as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is a new RNA virus strain that belongs to the beta-coronavirus 2b families in the evolutionary tree. COVID-19 had a reported overall casefatality rate (CFR) of 2.3 percent by this time, while cases in those aged 70 to 79 years had an 8.0 percent CFR and cases in those aged 80 and above had a 14.8 percent CFR. Severe pulmonary and extrapulmonary problems can result in respiratory failure and life-threatening events in certain individuals. D-dimer levels were found to be elevated in nearly half of the patients, and aberrant D-dimer levels are linked to a bad prognosis. As a result, in some stable individuals who die suddenly, acute organ failure, embolism, and infarction should be considered. Although the incidence of thrombosis in COVID-19 patients has not been identified, deep vein thrombosis (DVT) and pulmonary embolism (PE) were found to be 20.5 percent and 11.4 percent in SARS cases, respectively.