Physiological and histological effects of the antioxidant butylated hydroxytoluene (BHT) on white male rats exposed to starvation stress

Wedyan Yousif Al-tikrity, T. M. Al-Mashhadani
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Abstract

This study was done to find out the effect of the antioxidant Hydroxytoluene (BHT) on some physiological and histological variables of rats subjected to stress by starvation. 50 kg) starvation + BHT concentration (mg/kg 100) starvation + BHT concentration (50 mg/kg) starvation + olive oil). The data indicate that starvation decreases the sex hormones of rats exposed to stress by starvation Follicle Stimulating Hormone (FSH), Luteinizing Hormone(LH), Testosterone, and damage to testicular tissues, the antioxidant group BHT showed a concentration of (100,50 mg/kg) a protective effect against the negative effect of stress by starvation on sex hormones and testicular tissues by maintaining Its concentration is within its normal level, while the starvation group showed a negative effect on the concentration of sex hormones in the rats’ blood serum and testes tissue. The antioxidant BHT at concentrations of 50 and 100 mg/kg has an effective role in maintaining most of the physiological, biochemical, and histological variables from the negative effects of stress by starvation.
抗氧化剂丁基羟基甲苯(BHT)对饥饿应激的生理和组织学影响
本研究旨在探讨抗氧化剂羟基甲苯(BHT)对饥饿应激大鼠生理和组织学指标的影响。50 kg)饥饿+ BHT浓度(mg/kg) 100)饥饿+ BHT浓度(50 mg/kg)饥饿+橄榄油。结果表明,饥饿使饥饿应激大鼠性激素水平降低,促卵泡激素(FSH)、促黄体生成素(LH)、睾酮(Testosterone)水平降低,睾丸组织损伤程度降低,抗氧化组BHT(100、50 mg/kg)浓度维持在正常水平,对饥饿应激对性激素和睾丸组织的负面影响具有保护作用;而饥饿组则对大鼠血清和睾丸组织中的性激素浓度产生了负面影响。抗氧化剂BHT在50和100 mg/kg浓度下对维持饥饿应激的大部分生理、生化和组织学变量具有有效作用。
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