Carbohydrate Polymers最新文献_第6页

Novel antibacterial, antioxidant, and anti-inflammatory aminated chitosan hybrid quinoline Schiff base as multi-target agent: Design, molecular docking, and toxicity assessment 新型抗菌、抗氧化、抗炎胺化壳聚糖杂化喹啉希夫碱多靶点药物：设计、分子对接及毒性评价

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-07-11 DOI: 10.1016/j.carbpol.2025.124049

Yasser M. Abdel-Baky , Ahmed Ragab , Moustafa S. Abusaif , Yousry A. Ammar , Ahmed M. Omer

{"title":"Novel antibacterial, antioxidant, and anti-inflammatory aminated chitosan hybrid quinoline Schiff base as multi-target agent: Design, molecular docking, and toxicity assessment","authors":"Yasser M. Abdel-Baky , Ahmed Ragab , Moustafa S. Abusaif , Yousry A. Ammar , Ahmed M. Omer","doi":"10.1016/j.carbpol.2025.124049","DOIUrl":"10.1016/j.carbpol.2025.124049","url":null,"abstract":"<div><div>This study involves the synthesis of a novel 7-ethoxy-3-formyl-2-morpholino quinoline (MQ) derivative, which was hybridized with aminated chitosan (AMCH) to yield a new AMCH-MQ Schiff base. Structural characterization via <sup>1</sup>H NMR, FTIR, electronic spectra, XRD, and TGA confirmed successful hybridization. Ion exchange capacity decreased from 28.88 m<sub>eq</sub>/g (AMCH) to 15.71 m<sub>eq</sub>/g (AMCH-MQ), verifying covalent modification. Antibacterial efficacy against <em>E. coli</em> (Gram-negative) and <em>S. haemolyticus</em> (Gram-positive) exhibited dose-dependent enhancement, with inhibition zones reaching 43 mm and 35 mm, respectively, and a minimal inhibitory concentration (MIC) of 0.625 mg/mL. At 10 mg/mL, AMCH-MQ (2) suppressed 95 % of bacterial growth. The derivative demonstrates notable antioxidant activity, effectively scavenging free radicals at 46 %, surpassing AMCH's 26 % capacity. A dose-dependent increase in hemolysis inhibition was accomplished, reaching 84.8 %, indicating adequate anti-inflammatory activity. Toxicity predictions indicated a minimal risk of systemic adverse effects, supporting the in vitro cytotoxicity assays that validated the safety profile of AMCH-MQ, which showed a positive correlation with quinoline content. Molecular docking simulations identified robust interactions between AMCH-MQ and key enzymatic targets (DHFR, QSR, DNA gyrase), supported by favorable binding affinities and interaction diversity. These findings position AMCH-MQ as a non-toxic multi-bioactive agent with synergistic antibacterial, antioxidant, and anti-inflammatory properties.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"368 ","pages":"Article 124049"},"PeriodicalIF":10.7,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144665883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioinspired pullulan-tannic acid hydrogels with high toughness, stretchability, adhesion and self-healing properties 仿生普鲁兰-单宁酸水凝胶具有高韧性、拉伸性、粘附性和自愈性

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-07-11 DOI: 10.1016/j.carbpol.2025.124038

Qian Xiao , Yanqian Gong , Hui Zhou , Yuming Zhang , Qingwu Shen , Xiaohong Sun

{"title":"Bioinspired pullulan-tannic acid hydrogels with high toughness, stretchability, adhesion and self-healing properties","authors":"Qian Xiao , Yanqian Gong , Hui Zhou , Yuming Zhang , Qingwu Shen , Xiaohong Sun","doi":"10.1016/j.carbpol.2025.124038","DOIUrl":"10.1016/j.carbpol.2025.124038","url":null,"abstract":"<div><div>Inspired by the high-density hydrogen bonds in spider silk and the mussel adhesive mechanism, pullulan-tannic acid (TA) hydrogels with high stretchability, toughness, adhesiveness, and rapid self-healing capabilities were successfully fabricated via a hydrogen-bond-driven co-assembly strategy combined with controlled evaporation. Infrared spectroscopy confirmed the presence of hydrogen bonds between pullulan and TA, while scanning electron microscopy revealed the porous network structure of the hydrogels. The tensile strength (TS), Young's modulus (YM), and toughness values of PulTA5 hydrogels were 0.48 MPa, 19.17 MPa, and 268.10 MJ/m<sup>3</sup>, respectively, reflecting increases of 433.3 %, 1538.5 %, and 76.7 % compared to PulTA1 hydrogels. The self-healed PulTA5 hydrogels exhibited the highest TS and toughness, along with the lowest elongation at break (EAB) values among all tested hydrogels. Furthermore, PulTA5 hydrogels demonstrated the highest adhesion strength to glass, paperboard, and metal surfaces. These improvements are attributed to the formation of abundant hydrogen bonds and van der Waals forces in the PulTA5 system, as confirmed by molecular dynamics (MD) simulations, which enhance the cohesion of the hydrogel and contribute to its compact structure. This novel strategy for designing pullulan-based hydrogels that combine high toughness and self-healing properties holds promise for the development of biobased materials for food packaging applications.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"367 ","pages":"Article 124038"},"PeriodicalIF":10.7,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of the structure and properties of carboxymethyl sesbania gum and its antioxidant activity evaluation 羧甲基田菁胶的结构、性能表征及其抗氧化活性评价

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-07-11 DOI: 10.1016/j.carbpol.2025.124048

Xiaojia Bian , Kuaitian Wang , Na Zhang , Chen Wang , Donghui Geng , Yongqiang Cheng , Ning Tang

{"title":"Characterization of the structure and properties of carboxymethyl sesbania gum and its antioxidant activity evaluation","authors":"Xiaojia Bian , Kuaitian Wang , Na Zhang , Chen Wang , Donghui Geng , Yongqiang Cheng , Ning Tang","doi":"10.1016/j.carbpol.2025.124048","DOIUrl":"10.1016/j.carbpol.2025.124048","url":null,"abstract":"<div><div>Carboxymethylation is a widely recognized method for modifying galactomannans, often employed to enhance their solubility, stability, and biological activities. In this study, carboxymethyl <em>sesbania</em> gum (CMSG) was synthesized under different reaction conditions, and the influence of these conditions on the degree of substitution was systematically assessed. Alkaline conditions were crucial for carboxymethylation, with reaction temperature, time, and etherifying agent concentration significantly affecting the degree of substitution. The maximum degree of substitution of 0.91 was achieved using an alkali molar ratio of 6.885 and an etherifying agent ratio of 3.43, under either 60 °C for 4 h or 50 °C for 9 h, following alkalization at 30 °C for 1 h. Structural analysis confirmed successful modification and revealed non-selective carboxymethyl group substitution, along with a reduction in molecular weight and thermal stability due to hydrogen bond disruption. Notably, CMSG demonstrated enhanced protective effects on Caco-2 cells; higher degrees of substitution correlated with superior antioxidant activity. This improved activity is attributed to lower molecular weight and increased charge density, leading to elevated intracellular superoxide dismutase and glutathione peroxidase levels, consequently reducing reactive oxygen species and lipid peroxidation. These findings highlight the potential of CMSG as a functional biomaterial with enhanced antioxidant properties.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"367 ","pages":"Article 124048"},"PeriodicalIF":10.7,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144656513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Starch granule oxidation evaluation using laser confocal microscope-Raman spectroscopy: A novel analytical method 激光共聚焦显微镜-拉曼光谱法评价淀粉颗粒氧化：一种新的分析方法

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-07-11 DOI: 10.1016/j.carbpol.2025.124056

Xindong Xu , Kaiyang Shi , Ji Ma , Yuhuan Geng , Wenhong Gao , Mengwai Woo , Xin-An Zeng , Zhong Han

{"title":"Starch granule oxidation evaluation using laser confocal microscope-Raman spectroscopy: A novel analytical method","authors":"Xindong Xu , Kaiyang Shi , Ji Ma , Yuhuan Geng , Wenhong Gao , Mengwai Woo , Xin-An Zeng , Zhong Han","doi":"10.1016/j.carbpol.2025.124056","DOIUrl":"10.1016/j.carbpol.2025.124056","url":null,"abstract":"<div><div>The total degree of oxidation (TDO) of oxidized starch for food applications is typically evaluated by determining the sum of the carboxyl and carbonyl contents using titrimetric methods. However, these methods are often time-consuming, complex and do not differentiate between intra- and inter-granule oxidation, limiting in-depth studies on oxidized starch. Herein, by extracting intensity values at 478 and 1401 cm<sup>−1</sup> in the starch Raman spectra, we reported a method based on laser confocal microscope-Raman spectroscopy (LCM-Raman) to rapidly and non-destructively analyze the oxidation level of starch. Using <em>R</em><sub>1401/478</sub> as a color mapping factor, the oxidation level inside and outside the starch granules was visualized by the map-scanning of LCM-Raman, and a highly significant correlation between the average <em>R</em><sub>1401/478</sub> and the TDO determined by titration was observed (R<sup>2</sup> = 0.99327, <em>p</em> < 0.0001). The error of this method for detecting the TDOs of commercial oxidized starches was within 3 % when compared to the titration method, indicating a good accuracy in determining the starch oxidation level. In addition, the oxidation homogeneity between starch granules of different sizes was assessed using the line-scanning of LCM-Raman. In summary, these findings provided a practical tool to study structural changes in starch (related to C<img>O bond) at the granule scale.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"367 ","pages":"Article 124056"},"PeriodicalIF":10.7,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The insight in wheat starch entanglement behavior and its effect on starch gel in aqueous solution 小麦淀粉在水溶液中的缠结行为及其对淀粉凝胶的影响

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-07-11 DOI: 10.1016/j.carbpol.2025.124004

Lecheng Li , Hangyan Ji , Yanli Wang , Qiaoxin Zheng , Chao Qiu , Zhengyu Jin

{"title":"The insight in wheat starch entanglement behavior and its effect on starch gel in aqueous solution","authors":"Lecheng Li , Hangyan Ji , Yanli Wang , Qiaoxin Zheng , Chao Qiu , Zhengyu Jin","doi":"10.1016/j.carbpol.2025.124004","DOIUrl":"10.1016/j.carbpol.2025.124004","url":null,"abstract":"<div><div>The objective of this study is to investigate the behavior of starch entanglement and to elucidate the starch gelation process from the entanglement perspective. This study established a starch entanglement system based on overlap, entanglement, and concentrated concentrations in aqueous solution. Select the temperature at which starch is prone to form gel (4 °C) and the temperature at which starch begins to gelatinize (60 °C) for entanglement. The entangled starch structures were characterized in multi-scale, and aiming to investigate its entanglement formation behavior. Then, the effect of wheat starch entanglement on starch gel behavior was investigated. The analysis of spiral structure revealed the highest starch order degree at entanglement concentration (C<sub>e</sub>,2.98 %). Besides, the wheat starch entanglement enhanced starch-water binding and a layered gel-like structure at C<sub>e</sub>. The C<sub>e</sub> was found as the critical point for gel formation, with entanglement degree positively correlating with gel strength. The entanglement molecular weight (M<sub>e</sub>) of starch indicated that entanglement is influenced by temperature, concentration, and time, though concentrated-concentration systems were less affected by temperature and time (7 % and 12.02 %). These findings offer new insights into starch entanglement study and provide a reference for starch-based gel applications.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"368 ","pages":"Article 124004"},"PeriodicalIF":10.7,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144703692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low molecular weight Astragalus membranaceus polysaccharides alleviates dextran sulfate sodium-induced colitis in mice 低分子量黄芪多糖减轻硫酸葡聚糖钠所致小鼠结肠炎

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-07-10 DOI: 10.1016/j.carbpol.2025.124050

Meng Ye , Menghan Fan , Yi Zhao , Feng Wang , Xiaobing Yang , Wenbing Yao , Xiangdong Gao , Juping Yu , Wei Liu

{"title":"Low molecular weight Astragalus membranaceus polysaccharides alleviates dextran sulfate sodium-induced colitis in mice","authors":"Meng Ye , Menghan Fan , Yi Zhao , Feng Wang , Xiaobing Yang , Wenbing Yao , Xiangdong Gao , Juping Yu , Wei Liu","doi":"10.1016/j.carbpol.2025.124050","DOIUrl":"10.1016/j.carbpol.2025.124050","url":null,"abstract":"<div><div>Inflammatory bowel disease (IBD) treatment is challenged by limited efficacy and side effects of current therapies. While <em>Astragalus membranaceus</em> polysaccharides (APS) show anti-inflammatory potential, their structure-activity relationship is unclear. This study compared the therapeutic effects of the linear α-1,4-glucan APS-G2 and the branched-chain APS-A1, enzymatically derived APS oligosaccharides. Structure-function analysis revealed that the homogeneous α-1,4-glucan backbone of APS-G2 is essential for superior bioactivity, contrasting with the diminished efficacy of the heterogeneous, branched APS-A1. APS-G2 significantly suppressed pro-inflammatory cytokines, elevated anti-inflammatory mediators, and improved intestinal barrier integrity by preventing DSS-induced apoptosis of intestinal epithelial cells and promoting the expression of tight junction proteins. The underlying mechanisms involve coordinated regulation of the SIRT1/PGC-1α/NF-κB pathway and FXR-mediated signaling. These findings elucidate the structure-function relationships of APS derivatives and suggest that enzymatic engineering can enhance the therapeutic potential of polysaccharides for IBD management.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"367 ","pages":"Article 124050"},"PeriodicalIF":10.7,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Solvent-polarity-engineered hyaluronic acid aerogels: Synthesis of transparent nanofiber network for thermal insulation 溶剂极性工程透明质酸气凝胶：用于隔热的透明纳米纤维网络的合成

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-07-10 DOI: 10.1016/j.carbpol.2025.124055

Yufang Lu , Shanying Sui , Miao Cui , Jingxing Wang , Yufan Yang , Yuhan Sheng , Yi Zhang , Zhifang Sun

{"title":"Solvent-polarity-engineered hyaluronic acid aerogels: Synthesis of transparent nanofiber network for thermal insulation","authors":"Yufang Lu , Shanying Sui , Miao Cui , Jingxing Wang , Yufan Yang , Yuhan Sheng , Yi Zhang , Zhifang Sun","doi":"10.1016/j.carbpol.2025.124055","DOIUrl":"10.1016/j.carbpol.2025.124055","url":null,"abstract":"<div><div>Aerogels exhibit superior thermal management properties, while challenges in simple synthesis with mild reaction conditions, optical transparency, and flexibility limit their applications. This study presents a mild approach to produce transparent hyaluronic acid (HA) aerogels without the use of chemical cross-linkers. By regulating solvent polarity through methanol-isopropanol gradient exchange followed by supercritical drying, phase separation is induced, transforming HA molecular chains into a uniform nanofiber network. This structural evolution endows the aerogels with exceptional mechanical strength and flexibility while maintaining high transparency (90 % transmittance and 8.5 % haze at 600 nm). SEM analysis reveals the formation of a nanofiber network with an average diameter of 12.4 nm. Nitrogen adsorption measurements reveals a high surface area of 560.94 m<sup>2</sup> g<sup>−1</sup>. The slender nanofiber network results outstanding thermal insulation, achieving an ultralow thermal conductivity of 0.0243 W m<sup>−1</sup> K<sup>−1</sup> at a low density of 0.074 g cm<sup>−3</sup>. This work highlights the critical role of solvent-induced nanofiber assembly in balancing optical and mechanical properties, positioning HA aerogels as sustainable candidates for optically transparent infrared stealth materials.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"367 ","pages":"Article 124055"},"PeriodicalIF":10.7,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An ethyl cellulose-coated bacterial cellulose based hydrophobic and degradable straw-like materials towards drinking straws 一种以乙基纤维素包覆的细菌纤维素为基础的可降解吸管状疏水材料

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-07-09 DOI: 10.1016/j.carbpol.2025.124046

Ronghui Zhang , Bianjing Sun , Longyi Chen , Chuntao Chen , Dongping Sun

{"title":"An ethyl cellulose-coated bacterial cellulose based hydrophobic and degradable straw-like materials towards drinking straws","authors":"Ronghui Zhang , Bianjing Sun , Longyi Chen , Chuntao Chen , Dongping Sun","doi":"10.1016/j.carbpol.2025.124046","DOIUrl":"10.1016/j.carbpol.2025.124046","url":null,"abstract":"<div><div>Currently, we are facing global challenges like petrochemical resource depletion and plastic products induced environmental issues. Especially, the commonly used disposable straws in daily life represent potential issues like other plastic products. Overuse and inadequate handling of disposable straws could add burden to environmental problems due to their non-recyclability in most areas and incomplete biodegradability. Therefore, it is important to find a high-performance alternative to eliminate plastic straw-related environmental problems. Cellulose based derivative materials are recognized as sustainable substitutes for plastics, yet the hydrophilic nature restricts their application as straws. To solve this problem, this study introduces a microplastic-free straw made from ethyl cellulose (EC) enhanced bacterial cellulose (BC). This fabricated EC enhanced BC based straw exhibits improved mechanical properties with bending strength up to 66.82 MPa, good hydrophobicity with water contact angle up to 110°, and favorable heat resistance compared to raw BC based straws. These enhancements are attributed to its three-dimensional nanofiber network structure and intermolecular hydrogen bonds. Moreover, it can degrade completely decomposition within 20 days compared to the commercially available polylactic acid-based straw in soil. This EC enhanced BC based drinking straw is a health-conscious and environmentally friendly alternative to plastic straws.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"367 ","pages":"Article 124046"},"PeriodicalIF":10.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of electron beam irradiation pretreatment on the structure, physicochemical properties, and digestibility of starch-tannic acid complexes 电子束辐照预处理对淀粉-单宁酸配合物结构、理化性质及消化率的影响

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-07-09 DOI: 10.1016/j.carbpol.2025.124037

Youming Zuo , Fan Zhu , Shuo Jiang , Mei Li , Xiangli Kong

{"title":"Effect of electron beam irradiation pretreatment on the structure, physicochemical properties, and digestibility of starch-tannic acid complexes","authors":"Youming Zuo , Fan Zhu , Shuo Jiang , Mei Li , Xiangli Kong","doi":"10.1016/j.carbpol.2025.124037","DOIUrl":"10.1016/j.carbpol.2025.124037","url":null,"abstract":"<div><div>Electron beam irradiation (EBI) is a low-temperature, high-energy, non-thermal process that enables rapid, uniform treatment with minimal residual effects compared to conventional irradiation techniques, making it particularly suitable for modifying sensitive biopolymers like starch and its application in functional food. Our study explored EBI for modifying corn starch (CS) and enhancing its interaction with tannic acid (TA) to form starch–polyphenol complexes. CS was pretreated with EBI at varying doses, and subsequently complexed with TA. The resulting CS–TA complexes were characterized in terms of their multiscale structure, physicochemical properties, and digestibility. At 10 % TA loading, EBI pretreatment promoted CS–TA binding, leading to notable alterations in crystalline order and pasting behavior, particularly at 5 kGy and 20 kGy. While EBI did not visibly alter starch morphology, it significantly improved the thermal stability of CS–TA complexes. Additionally, the <em>in vitro</em> digestibility of the complexes was jointly influenced by the EBI dose and TA concentration. These findings highlight the unique potential of EBI technology for tuning starch–polyphenol interactions, offering a clean and effective approach for designing functional food ingredients with enhanced stability and nutritional properties.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"367 ","pages":"Article 124037"},"PeriodicalIF":10.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can high-molar-mass cellulose molecules be extracted from phosphorylated pulp and TEMPO-oxidized pulps or their nanofibrils using LiCl/DMAc? 利用LiCl/DMAc可以从磷酸化纸浆和tempo氧化纸浆或其纳米原纤维中提取高摩尔质量纤维素分子吗？

IF 10.7 1区化学

Carbohydrate Polymers Pub Date : 2025-07-09 DOI: 10.1016/j.carbpol.2025.124035

Gaoyuan Hou , Korawit Chitbanyong , Izumi Shibata , Akira Isogai

{"title":"Can high-molar-mass cellulose molecules be extracted from phosphorylated pulp and TEMPO-oxidized pulps or their nanofibrils using LiCl/DMAc?","authors":"Gaoyuan Hou , Korawit Chitbanyong , Izumi Shibata , Akira Isogai","doi":"10.1016/j.carbpol.2025.124035","DOIUrl":"10.1016/j.carbpol.2025.124035","url":null,"abstract":"<div><div>Phosphorylated (P-) and TEMPO-oxidized (TO-) wood cellulose fibers (pulps), and P- and TO-cellulose nanofibrils (CNFs) were prepared. To extract pure cellulose molecules, all samples were dispersed in water and freeze-dried, and the P-/TO-pulp and P-/TO-CNF samples were stirred in 8 % (<em>w</em>/w) lithium chloride/<em>N,N</em>-dimethylacetamide (LiCl/DMAc). The quantities of the extracted LiCl/DMAc-soluble fractions and molar-masses of the constituents were determined using size-exclusion chromatography. The structures of the LiCl/DMAc-insoluble fractions were analyzed using X-ray diffraction (XRD) and solid-state <sup>13</sup>C-nuclear magnetic resonance (NMR). The mass ratios of the LiCl/DMAc-extracted fractions obtained from the P-/TO-pulp and P-/TO-CNF samples were in the low range of 2–9 %, consisted with the hypothesis that structurally, all the cellulose molecules in each cellulose microfibril of the P-/TO-pulp and P-/TO-CNF samples possess some phosphate ester groups or C6-carboxy groups. These cellulose molecules containing phosphate ester groups or C6-carboxy groups were insoluble in LiCl/DMAc. XRD and NMR analyses of the LiCl/DMAc-insoluble fractions of the TO-pulp samples showed that the cellulose I crystal structures inside the cellulose microfibrils were transformed into disordered structures by pretreatment with EDA. In contrast, the cellulose I crystal structure of the P-pulp was stable in EDA and was retained after post-treatment.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"367 ","pages":"Article 124035"},"PeriodicalIF":10.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144597096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0