Journal of Umm Al-Qura University for Medical Sciences最新文献_第5页

Novel Drug Treatments for Diabetes Complications 糖尿病并发症的新型药物治疗

Journal of Umm Al-Qura University for Medical Sciences Pub Date : 2020-11-01 DOI: 10.54940/ms86676560

Fatmah A. Bakhdar

{"title":"Novel Drug Treatments for Diabetes Complications","authors":"Fatmah A. Bakhdar","doi":"10.54940/ms86676560","DOIUrl":"https://doi.org/10.54940/ms86676560","url":null,"abstract":"Diabetes mellitus is a metabolic disease associated with elevated levels of blood glucose. It has become the most prevalent disease in the Saudi population according to the last report from the national prevention program. Diabetes cases can be divided into three types: type I, which requires insulin therapy; type II, which requires the use of hypoglycemic drugs, with or without insulin, and is the most common type in Saudi Arabia; and gestational diabetes, which occurs during pregnancy. We must remember that diabetes can be very dangerous, causing complications in many parts of the body, like the nerves, heart, eyes, and kidneys. According to previous studies, these complications vary depending on the severity of diabetes. They may also affect the blood vessels of the retina, which can develop into diabetic retinopathy. Complications may also be fatal, in the cases of heart attacks, angina, and atherosclerosis. Additionally, they may cause poor circulation that leads to infection and gangrene, or cause neuropathy with numbness and a loss of pain sensations. Diabetic nephropathy is another harmful effect of diabetes that attacks the renal blood vessels. In this article, my aim was to review newly discovered drugs that target and decrease the complications produced by diabetes. My focus here was on certain drugs, including those using nanotechnology, cell-based therapy, angiopoietin like 4, baricitinib, and hepatocyte growth factor (HGF) gene therapy.","PeriodicalId":256236,"journal":{"name":"Journal of Umm Al-Qura University for Medical Sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131292875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sero-prevalence of Hepatitis B Virus infections among blood banking donors in Makkah city, Saudi Arabia: an institutional-based cross-sectional study 沙特阿拉伯麦加市血库献血者乙型肝炎病毒感染的血清患病率:一项基于机构的横断面研究

Journal of Umm Al-Qura University for Medical Sciences Pub Date : 2020-11-01 DOI: 10.54940/ms67885003

M. Abdel-fattah, Omar Al-Marhb, Mohammed Matrafi, Mohamed Babaseel, Mashari Asmari, Soliman Eletiany

{"title":"Sero-prevalence of Hepatitis B Virus infections among blood banking donors in Makkah city, Saudi Arabia: an institutional-based cross-sectional study","authors":"M. Abdel-fattah, Omar Al-Marhb, Mohammed Matrafi, Mohamed Babaseel, Mashari Asmari, Soliman Eletiany","doi":"10.54940/ms67885003","DOIUrl":"https://doi.org/10.54940/ms67885003","url":null,"abstract":"Introduction: Worldwide about 350 million people are infected with chronic hepatitis B (HBV) putting HBV infection among the most serious infectious disease problems. Blood transfusion is vital in saving lives but is associated with transfusion-transmittable infections e.g.HBV which can lead to adverse consequences. Objective: To determine HBV infection prevalence between donors of blood banking in Makkah,Saudi Arabia. Methods: An institutional-based cross-sectional study was conducted among 2024 blood donors in two hospitals blood banks. Data were collected using laboratory blood screening tools. Data were analyzed using the SPSS statistical program. Statistically significance was considered at p < 0.05. Results: Our study was conducted on 4024 blood donor’s data. For Saudi donors, statistical analysis of HBV results has showed that 1% of donors were +ve for HBsAg and 6.8% of donors were +ve for anti-HBc. The results of NAT have showed that 1.1% of donors were positive and all were males. There is a high significance in age between 30-39 and 40-49 for NAT. The overall prevalence of HBsAg was 1% in Saudi donors. For non-Saudi donors, HBV results showed that 0.5% and 12.8% of donors were positive for HBsAg test and Anti-HBc test, respectively. The results of the Anti-HBc test were highly significant for the age range 30-39. The statistical analysis of NAT results showed that 0.8% of donors were positive and all were males. The overall prevalence of the HBsAg test among non-Saudi donors was 0.5%. Conclusion: The HBsAg and anti-HBc rates among blood donors have declined significantly. NAT is an important tool for viral detection which is expensive and not available everywhere. The total HBV prevalence between donors in Makkah was very low which may be due to recommended safety regulations followed in Makkah as its religious importance and application of an effective vaccine program.","PeriodicalId":256236,"journal":{"name":"Journal of Umm Al-Qura University for Medical Sciences","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126262499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Parental Knowledge and Attitude About the Emergency Management of Traumatic Dental Injuries and the Predictive Factors Affecting their Knowledge - A Cross Sectional Study in Makkah, Saudi Arabia 父母对创伤性牙齿损伤应急管理的知识和态度以及影响其知识的预测因素——沙特阿拉伯麦加的一项横断面研究

Journal of Umm Al-Qura University for Medical Sciences Pub Date : 2020-11-01 DOI: 10.54940/ms68173412

Fawaz Alansari, N. Alkhuzea, Mshari Alzahrani, Moataz Alqurashi, Walid Fouad, Omair M Bukhari, Waleed Taju, Jameel Abuljadayel

{"title":"Parental Knowledge and Attitude About the Emergency Management of Traumatic Dental Injuries and the Predictive Factors Affecting their Knowledge - A Cross Sectional Study in Makkah, Saudi Arabia","authors":"Fawaz Alansari, N. Alkhuzea, Mshari Alzahrani, Moataz Alqurashi, Walid Fouad, Omair M Bukhari, Waleed Taju, Jameel Abuljadayel","doi":"10.54940/ms68173412","DOIUrl":"https://doi.org/10.54940/ms68173412","url":null,"abstract":"Background:Traumatic dental injuries (TDIs) are common dental problems among children worldwide. Some of these injuries occur at home, where parents are considered responsible for reporting them and taking the first action, which directly can influence the prognosis. The present study aims to quantify the level of parents’ knowledge and attitude towards emergency management of TDI and to predict the factors that affect their level of knowledge. Subject and Methods: 269 questionnaires were completed by parents who live in Makkah, Saudi Arabia. The questionnaire was divided into three parts, including questions on demographic data, knowledge, and attitude about emergency management, and self-assessed knowledge and attitude toward further education on TDI emergency management. Results: The average knowledge score was 2 out of 9 (SD±1.9). More than 78% of the participants were enthusiastic about further free education and believed that they don’t have enough knowledge about TDI. A significant positive association has been predicted, using a multivariable Poisson model, between the parental knowledge score and their willingness to attend free lessons, having a previous idea about TDI, higher educational background, confidence, and higher socioeconomic class (SEC). However, the history of a previous TDI was predicted to have a significant negative influence on the knowledge score (p values <0.05). Conclusion: Parents of children in Makkah city show a weak level of knowledge about TDI emergency management. A concerning attitude was shown as parents tend to proceed to manage TDIs against the recommended managements rather than seeking professional advice. A specific dental educational program targeting parents is essential.","PeriodicalId":256236,"journal":{"name":"Journal of Umm Al-Qura University for Medical Sciences","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114139478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hematological Changes in Diabetic Rats Receiving Melatonin, Vitamin D and Vitamin E are Not Reliable Indices of Inflammatory Changes 接受褪黑素、维生素D和维生素E治疗的糖尿病大鼠血液学变化不是炎症变化的可靠指标

Journal of Umm Al-Qura University for Medical Sciences Pub Date : 2020-11-01 DOI: 10.54940/ms84898451

Abdulmonim A. Alqasim

{"title":"Hematological Changes in Diabetic Rats Receiving Melatonin, Vitamin D and Vitamin E are Not Reliable Indices of Inflammatory Changes","authors":"Abdulmonim A. Alqasim","doi":"10.54940/ms84898451","DOIUrl":"https://doi.org/10.54940/ms84898451","url":null,"abstract":"Background: Finding a suitable model to study the effect of various treatments on diabetes will help to avoid undesirable effect on humans during empirical investigation. This study aims to evaluate the values of biomarkers such as Neutrophil-Lymphocyte Ratio (NLR), Platelet-Lymphocyte Ratio (PLR), and Lymphocyte-Monocyte Ratio (LMR) in monitoring diabetes in a rat model subject to treatment with melatonin, vitamin-D and vitamin-E. Methods: Male albino rats (n=8-10 per group), normal and with diabetes were divided as follows into 12 groups: G1 normal fed, received no medications; G2 normal, treated with melatonin; G3 normal, treated with vitamin-E; G4 normal, treated with vitamin-D; G5 diabetic; received no medications; G6 diabetic, treated with insulin; G7 diabetic treated with melatonin; G8 diabetic, treated with melatonin and insulin; G9 diabetic, treated with vitamin-E; G10 diabetic, treated with vitamin-E and insulin; G11 diabetic, treated with vitamin-D and G12 diabetic, treated with vitamin-D and insulin. Two months post-treatment, hematological (NLR, PLR and LMR) and biochemical examination of glucose profile and oxidative stress status, were performed. Results: NLR is significantly decreased on comparing G3 and G4 with G1, and significantly increased on comparing G9 with G1. On comparing G3 with G5 and G6, NLR is significantly decreased, but on comparing G9 with G5 and G6, NLR is significantly increased. However, PLR and LMR showed no statistically significant changes in all rat groups. Conclusion: Hematological changes in diabetic rat model receiving melatonin, vitamin D and E are not reliable indices of inflammatory changes.","PeriodicalId":256236,"journal":{"name":"Journal of Umm Al-Qura University for Medical Sciences","volume":"04 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131039548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In Vitro Comparison of Gutta-Percha Removal Using XP Endo Finisher and ProTaper With or Without Organic Solvent by Scanning Electron Microscope 使用或不使用有机溶剂的XP Endo清净剂和ProTaper去除杜仲胶的体外扫描电镜比较

Journal of Umm Al-Qura University for Medical Sciences Pub Date : 2020-11-01 DOI: 10.54940/ms52912441

Ashwag Barnawi, May Al-Guhi, Bayan Baraheem, E. Malki, Majed A. Almalki, H. Fansa

{"title":"In Vitro Comparison of Gutta-Percha Removal Using XP Endo Finisher and ProTaper With or Without Organic Solvent by Scanning Electron Microscope","authors":"Ashwag Barnawi, May Al-Guhi, Bayan Baraheem, E. Malki, Majed A. Almalki, H. Fansa","doi":"10.54940/ms52912441","DOIUrl":"https://doi.org/10.54940/ms52912441","url":null,"abstract":"Introduction: Non-surgical endodontic retreatment is highly dependent on the removal of previous root filling material, bacteria and necrotic tissue. Various techniques and instruments have been used for endodontic retreatment. Recently, the XP-endo Finisher has been introduced in endodontic treatment to clean highly complex morphologies and difficult to reach areas. Aims: a) To compare the effectiveness of XP-endo Finisher and ProTaper universal retreatment system with or without organic solvent in removing gutta-percha. b) To compare the amount of apically extruded debris between the groups. Methods: 24-human- extracted, single-rooted teeth were divided into three groups of 8. The groups were classified as follows: Group I: using a ProTaper universal retreatment system with chloroform. Group II: using a ProTaper universal retreatment system without chloroform. Group III: using a ProTaper universal retreatment system followed by XP-endo Finisher without chloroform. The apically extruded debris was collected during the retreatment and weighted. The roots were split longitudinally. The degree of dentinal tubules patency was evaluated by scanning electron microscopy. Results: The most intensely clear dentinal tubules were observed in group III, followed by group II and group I, respectively. Group I resulted in a debris extrusion, significantly less, as compared with the other groups (P < 0.05). While there was no notable difference between group II and group III (P > 0.05). Conclusion: Under the conditions of the present study, out of all the retreatment techniques that were used, the XPendo Finisher was the most effective in the removal of the gutta-percha in cervical, middle and apical thirds. The use of solvent during retreatment can decrease the amount of the apically extruded debris.","PeriodicalId":256236,"journal":{"name":"Journal of Umm Al-Qura University for Medical Sciences","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125974513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge and Attitude Towards Total Knee Arthroplasty Among Health Education Students in Saudi Arabia 沙特阿拉伯健康教育学生对全膝关节置换术的知识和态度

Journal of Umm Al-Qura University for Medical Sciences Pub Date : 2020-06-01 DOI: 10.54940/ms18255749

L. Amer, Alaa Alageel, Mashael Alenezi, Rawand Alhumood, Amani Alnamshan, F. Almoayad

{"title":"Knowledge and Attitude Towards Total Knee Arthroplasty Among Health Education Students in Saudi Arabia","authors":"L. Amer, Alaa Alageel, Mashael Alenezi, Rawand Alhumood, Amani Alnamshan, F. Almoayad","doi":"10.54940/ms18255749","DOIUrl":"https://doi.org/10.54940/ms18255749","url":null,"abstract":"Objectives: Total knee Arthroplasty (TKA) is considered the treatment of choice for knee osteoarthritis, and health educators can assist patients to choose the most appropriate treatment plan. This research aims to measure knowledge of and attitudevs towards TKA among health education students, as they are the health educators of the future. Methods: A cross sectional design was used to study 227 health education students from four Saudi universities that offered a health education program. A questionnaire was distributed to eligible participants during the 7-month study period (20 September 2017 until 17 April 2018). Data were analyzed using SPSS. A chi-square test to measure the association between the different groups in terms of categorical variables and a Spearman’s correlation test were conducted. Poor knowledge rated as 0-49%; fair knowledge 50-74%; and good knowledge 75-100%. A total score of more than 7.2 indicated positive attitude, more than 4.6-7.2 neutral attitude and less than 4.6 negative attitude. Results: Of all participants, 71.40% had poor knowledge of TKA, while 76.20% had a neutral attitude towards it. Participant’s level of knowledge was significantly associated with having previously heard about TKA and having a family member who had undergone surgery. Participants’ attitude was significantly associated with having previously heard about TKA. Conclusions: Overall, knowledge of TKA was poor, and attitude towards it was neutral. A correlation was found between participants’ level of knowledge and attitude. Further studies for exploration are needed among health-care professionals including orthopedic surgeons and health educators.","PeriodicalId":256236,"journal":{"name":"Journal of Umm Al-Qura University for Medical Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114748031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of CYP 450 Isozymes in Drug-Drug Interaction cyp450同工酶在药物-药物相互作用中的作用

Journal of Umm Al-Qura University for Medical Sciences Pub Date : 2020-06-01 DOI: 10.54940/ms53396452

Fatmah A. Bakhdar

引用次数: 2

Hepatitis B: Knowledge, Preventive Attitude and Vaccine Status of Dental Students and Interns at Umm Al-Qura University, Makkah, Saudi Arabia 沙特阿拉伯麦加乌姆库拉大学牙科专业学生和实习生的乙肝知识、预防态度和疫苗接种状况

Journal of Umm Al-Qura University for Medical Sciences Pub Date : 2020-06-01 DOI: 10.54940/ms45403892

A. Al-Zahrani, Rahaf Al-Sulimani, Mashael Al-Qahtani, Ibtesam Afif

{"title":"Hepatitis B: Knowledge, Preventive Attitude and Vaccine Status of Dental Students and Interns at Umm Al-Qura University, Makkah, Saudi Arabia","authors":"A. Al-Zahrani, Rahaf Al-Sulimani, Mashael Al-Qahtani, Ibtesam Afif","doi":"10.54940/ms45403892","DOIUrl":"https://doi.org/10.54940/ms45403892","url":null,"abstract":"Background: Cross infection of blood-borne pathogens during dental practice is a major infection control problem among dental health care workers. Of these infections, Hepatitis B causes significant morbidity and mortality, and imposes a great burden on the Saudi Arabia healthcare system. Therefore, awareness of Hepatitis B virus (HBV) infection, routes of transmission, preventive practices and vaccination are very important for the protection of dental students. Aim: Determination of the level of knowledge, attitude and practice of preventive measures regarding the HBV as well as vaccine status among Umm Al-Qura University (UQU) dental students and interns. Method: A descriptive cross sectional study was conducted on 182 undergraduate students in fourth, fifth and sixth grades as well as on interns at Umm Al-Qura College of Dentistry. A self-structured questionnaire of 31 questions was distributed among participants to determine knowledge, attitude, preventive measures about hepatitis B during dental practice as well as the vaccine status. Data were collected, tabulated and statistically analyzed by SPSS v.20. Results: 182 questionnaires were answered, total males were 88 (48.4%) and females were 94 (51.6%). Among all students in 4th, 5th, 6th grades and interns, the overall knowledge was high (>70%). Also the scores for total attitude and knowledge about HBV infection were significantly higher in females than males (p<0.001). All participants were vaccinated against HBV and received 1-3 doses. However, 10.9% of them did not complete their doses (they received only 2 doses). Conclusions: UQU dental students and interns showed high knowledge and attitude about many aspects of HBV infection, but also there are some aspects in which they showed poor knowledge. So, sustained training and awareness about HBV infection and its preventive measures are recommended.","PeriodicalId":256236,"journal":{"name":"Journal of Umm Al-Qura University for Medical Sciences","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115726699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Assessment of Oral Hygiene Knowledge, Attitude and Practice Among Children in Makkah City, Saudi Arabia: a Cross-Sectional Study 沙特阿拉伯麦加市儿童口腔卫生知识、态度和行为的评估:一项横断面研究

Journal of Umm Al-Qura University for Medical Sciences Pub Date : 2020-06-01 DOI: 10.54940/ms53031907

Naif M. Bafaraj, Mohammad Bafaraj, Duha Alzaidi, Razan Alhajjaji, Hanouf Alharbi, Noura R. Alhomaidhi, Hind Abdel-latif

{"title":"Assessment of Oral Hygiene Knowledge, Attitude and Practice Among Children in Makkah City, Saudi Arabia: a Cross-Sectional Study","authors":"Naif M. Bafaraj, Mohammad Bafaraj, Duha Alzaidi, Razan Alhajjaji, Hanouf Alharbi, Noura R. Alhomaidhi, Hind Abdel-latif","doi":"10.54940/ms53031907","DOIUrl":"https://doi.org/10.54940/ms53031907","url":null,"abstract":"Background: Assessment of knowledge, attitude and practice of oral hygiene in children is important for the health of the community. The lack of data in Makkah region initiated the idea of the study. Aims: To assesses the knowledge, attitude, and practice of oral hygiene among Makkah children aged 9-14years. Design: Cross sectional study was conducted to collect data from children in Makkah, using self-administered close-ended validated questionnaire. It contained demographic data about the child and his mother, and included ten items about oral health practice, oral health attitude, and oral health knowledge that were answered by the child and his guardian separately. SPSS version 20 was used for the analysis of the data and descriptive statistics and chi- square tests were applied. Results: 405 children, both males and females, and their mothers have participated, 79% of them were Saudi mothers and 57% have had higher education. A significant difference was found regarding the correct tooth brushing frequency among male and female children. 67% had more than two episodes of dental pain during last year. No significant difference was found regarding the knowledge except the effect of the fluoride on teeth. More than 45% of the children who got good score their mothers are University graduates. Conclusion: Most of the children and their mothers have adequate oral hygiene knowledge, practice, and attitude. Children of university graduate mothers are more knowledgeable compared to non-graduate mothers; this necessitates the importance of educating them.","PeriodicalId":256236,"journal":{"name":"Journal of Umm Al-Qura University for Medical Sciences","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131506123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Prevalence and related potential risk factors of Toxoplasma gondii infection among slaughterhouse workers and animals in Makkah 麦加屠宰场工人和动物中刚地弓形虫感染的流行及相关潜在危险因素

Journal of Umm Al-Qura University for Medical Sciences Pub Date : 2020-06-01 DOI: 10.54940/ms43256259

Khalil Mohamed, Ibrahem Bukhari, Sultan Ansari, Abdulwahab Khayat, Ramzy Shiku, Mohammed Brashi, Narjes Degnah, A. Malki, Mohand Gafar, Mohamed Bakri, M. Abdel-fattah

{"title":"Prevalence and related potential risk factors of Toxoplasma gondii infection among slaughterhouse workers and animals in Makkah","authors":"Khalil Mohamed, Ibrahem Bukhari, Sultan Ansari, Abdulwahab Khayat, Ramzy Shiku, Mohammed Brashi, Narjes Degnah, A. Malki, Mohand Gafar, Mohamed Bakri, M. Abdel-fattah","doi":"10.54940/ms43256259","DOIUrl":"https://doi.org/10.54940/ms43256259","url":null,"abstract":"Toxoplasma gondii is a protozoan parasite that causes a parasitic disease known as toxoplasmosis. The disease transmits from animals to humans via the eating raw or insufficient cook meat or by contact with raw meat. The main aim of the present study was to define the prevalence and the associated risk factors of the disease in workers and animals in slaughterhouses in Makkah. The study was based on a cross-sectional study in humans and animals including, sheep, goats, cattle, and camels. Data were collected using a short questionnaire. Approximately 108 blood samples were collected from workers included the butchers and the workers and 160 blood samples of the slaughterhouse animals. Serum samples were kept in -80o C till examined by using ELISA IgM and IgG tests. The data analyzed by using SPSS version 25. The result showed that the prevalence in workers was 0.9% and 25% using IgM and IgG, respectively. In animals, all the results were negative using ELISA IgM and IgG tests. The result showed that there was a correlation between chronic infection and contact with a cat (p<0.015). The study focussed on the T. gondii in slaughterhouse workers which found that both acute and chronic toxoplasmosis. The results also showed no infection was registered in different species of animals in both slaughterhouses.","PeriodicalId":256236,"journal":{"name":"Journal of Umm Al-Qura University for Medical Sciences","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122333806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1