ACS Sensors最新文献

{"title":"Coupling Luciferase Activation and Bioluminescence Resonance Energy Transfer Enables High-Contrast Red-Window Calcium Imaging.","authors":"Rachna Sharma, Ying Xiong, Xiaodong Tian, Ponnusamy Pon Sathieshkumar, Hui-Wang Ai","doi":"10.1021/acssensors.6c03486","DOIUrl":"https://doi.org/10.1021/acssensors.6c03486","url":null,"abstract":"<p><p>Genetically encoded bioluminescent calcium indicators enable excitation-free imaging of Ca2+ dynamics with low background and without excitation-associated photobleaching. However, many exhibit lower dynamic ranges than their fluorescent counterparts, motivating the development of new sensor configurations, particularly for imaging in the red optical window, where tissue absorption and scattering are reduced. Here, we developed HyBRIC and HyBRIC2, two hybrid indicators that integrate Ca2+-dependent luciferase activation and bioluminescence resonance energy transfer (BRET) within a single molecular architecture. When paired with pyCTZ luciferin, they exhibited an approximately 55-fold Ca2+-dependent signal increase in red-window emission in vitro. Compared with HyBRIC, HyBRIC2 showed improved brightness and responsiveness in mammalian cells. It robustly resolved induced Ca2+ dynamics in HEK293T and HeLa cells, with particularly strong red-window responses. Together, these findings expand the limited repertoire of responsive red-window bioluminescent calcium indicators and establish hybrid sensing as a modular strategy for improving biosensor contrast.</p>","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149177927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smart Oral Capsule with a Closed-Loop Sense-Decide-Act Strategy for Colitis Therapy.","authors":"Wen Pan, Jie Fu, Shouzhe Deng, Lizhi Lin, Dingxi Lu, Jiawang Wang, Fanyu Mu, Uul Gegeen, Yihong Ding, Shuang Li, Dong Ming","doi":"10.1021/acssensors.6c02826","DOIUrl":"https://doi.org/10.1021/acssensors.6c02826","url":null,"abstract":"<p><p>Current treatments for inflammatory bowel disease (IBD) lack real-time inflammatory monitoring and lesion-specific drug delivery, resulting in poor efficacy and systemic toxicity. To address this, we present a smart oral capsule that operates a closed-loop \"sense-decide-act\" strategy entirely autonomously-sensing and drug release are driven by changes in the digestive tract environment without any external intervention. The capsule features a dual-layer shell sequentially responsive to pH and matrix metalloproteinases (MMPs), enabling colon-targeted delivery and inflammation-specific activation. An integrated multimodal sensor wirelessly tracks colonic TNF-α (>5 ng mL-1), pH (>7.0), and Na+ (>100 mM). The encapsulated budesonide nanoparticles (Bud@PEG-SS-NPs) release the drug specifically in reactive oxygen species (ROS)-rich microenvironments and show superior anti-inflammatory efficacy in both lipopolysaccharide (LPS)-induced cellular models and dextran sulfate sodium (DSS)-induced mouse colitis. In live rats, the capsule achieved on-demand drug release in response to elevated local TNF-α levels, and a single intervention significantly alleviated inflammation. This work establishes a new paradigm for personalized, adaptive IBD therapy and provides a versatile platform for closed-loop management of other gastrointestinal diseases.</p>","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149177943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Designer Redox Reporters for Reactive Oxygen-Free, Nucleic Acid-Based Electrochemical Sensing.","authors":"Jacob A Weber, Yuchan Yuan, Rotdalmwa J Dimka, Khoa Huan Nguyen, Maxime A Siegler, William A Hearne, Netzahualcóyotl Arroyo-Currás","doi":"10.1021/acssensors.6c02652","DOIUrl":"https://doi.org/10.1021/acssensors.6c02652","url":null,"abstract":"<p><p>Aptamer-based molecular monitors enable continuous, real-time tracking of analytes in complex environments, including in vivo, but their practical deployment is limited by short operational lifetimes of only hours. This instability arises in part from the electrochemical interrogation of the aptamer-bound redox reporter methylene blue, whose standard potential overlaps with oxygen reduction on gold electrodes, leading to peroxide generation and, concomitantly, accelerated sensor degradation. We previously demonstrated that peroxide accumulates to tens-to-hundreds of micromolar on the sensor surface under typical operating conditions. Here, we address this limitation by rationally designing redox reporters with more positive standard potentials, beyond the range of oxygen electroreduction. Using electron-withdrawing substituents and extended conjugation strategies, we developed a new reporter, Netz Lab Blue, exhibiting a standard potential 160 mV more positive than methylene blue. Aptamer-based monitors incorporating Netz Lab Blue withstand ≥10,000 interrogation cycles in buffered saline without measurable signal loss, whereas methylene blue-based sensors lose >20% signal under identical conditions. In oxygen-saturated solutions, Netz Lab Blue-based sensors retain full stability over the same duty cycle while methylene blue-based devices fail completely. Additionally, Netz Lab Blue delivers 40% higher signal gain for the same aptamer sequence and under identical packing density relative to methylene blue. These improvements translate directly to biological environments, where Netz Lab Blue‑based sensors exhibit stable performance in rat blood and support continuous, real‑time in vivo drug monitoring in the brain of rodents using two distinct aptamer sensors. By eliminating peroxide generation during electrochemical interrogation, this new redox reporter markedly extends sensor lifetime and performance, potentially enabling continuous molecular monitoring over days to weeks in biomedical applications that seek to interrogate human physiology.</p>","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-Powered Multivariable Organic Photovoltaic Sensors for Accurate Volatile Organic Compound Discrimination.","authors":"Huanran Feng, Zhihui Liu, Taoping Liu, Yunhe Li, Chuang Yu, Siwu Li, Yinhui Bao, Xing Chen, Chen Su, Danyao Qu, Hossam Haick, Weiwei Wu","doi":"10.1021/acssensors.6c03607","DOIUrl":"https://doi.org/10.1021/acssensors.6c03607","url":null,"abstract":"<p><p>Most existing VOC sensors rely on battery power and only single-parameter outputs, limiting long-term deployment, maintenance efficiency, and chemical discrimination. Here, we report a self-powered multivariable photovoltaic sensor (MPVS) that repurposes an organic photovoltaic junction as an information-rich VOC sensing platform. By integrating a gas-permeable silver nanowire electrode with a donor-acceptor bulk-heterojunction active layer, the MPVS enables efficient analyte access while maintaining stable photovoltaic operation under illumination. Exposure to VOCs induces coupled and reversible changes in open-circuit voltage (VOC) and short-circuit current density (JSC), providing two orthogonal sensing features without external power input. Using a single PM6:Y6 junction, we demonstrate concentration-dependent responses and reliable discrimination of representative VOCs. Extending the concept to a five-element MPVS array incorporating different Y-series acceptors generates high-dimensional photovoltaic fingerprints that enable accurate identification of eight chemically distinct VOCs. Density functional theory (DFT) calculations and in situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) reveal that analyte-dependent noncovalent interactions, particularly strong hydrogen bonding in the case of formic acid, underlie the observed selectivity. By integrating energy harvesting and multivariate sensing within a single organic photovoltaic platform, this work establishes a scalable, battery-free approach to artificial olfaction, offering a promising pathway for distributed and long-term VOC monitoring systems.</p>","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Matrix-Based Specific T-Cell Activation Reporter for Nearly-Digital Mapping of Antigen-Specific T Cells via Heterotypic Cell Micro-Communities and Digital Microfluidics.","authors":"Hangjia Tu, Mengxing Mou, Chenxuan Hu, Jinxin Fu, Xiaotian Tan, Yuzhong Xu, Ji Huang, Wenxin Yan, Wenjuan Wu, Peijin Wang, Tianyuan Zhao, Jianheng Huang, Binmao Zhang, Chengbin Yang, Hanbin Ma, Siyi Hu, Yujuan Chai","doi":"10.1021/acssensors.6c03405","DOIUrl":"https://doi.org/10.1021/acssensors.6c03405","url":null,"abstract":"<p><p>Antigen-specific T cells constitute a low percentage of peripheral blood mononuclear cells (PBMCs) and require antigen presentation by autologous antigen-presenting cells for activation and cytokine secretion. Conventional interferon-γ release assay (IGRA) averages rare activation events beyond cellular resolution, while single-cell compartmentalization disrupts the intracellular synapses for T cell immunity. Here, we developed mSTAR (matrix-based Specific T-cell Activation Reporter), an active-matrix digital microfluidic platform that partitions microliters of PBMCs into a nanoliter-scale matrix of 16 cell microcommunities (CMCs), each retaining tens to hundreds of PBMCs in their native heterotypic composition to preserve the natural physiological immune response. In a proof of concept, mSTAR executes parallel IGRA for a tuberculosis disease model, including CMC stimulation and magnetic-bead-based immunofluorescence assay. The IGRA of the mSTAR system achieves a limit of detection of 3.70 pg/mL, yielding 16 interferon-γ quantification readouts and ratios between CMCs incubated with different stimulants (negative, positive, or specific antigen). This enables the mapping and reporting of activated antigen-specific T cells in the matrix, thereby achieving functional phenotyping of each CMC. Poisson-based modeling of the droplet matrix converts rare T-cell activation events into a nearly digital estimation, and the positive CMCs encapsulating target cells can be retrieved for further characterization without loss. By bridging functional phenotyping and molecular features without prior cell sorting or engineering, mSTAR provides a programmable immunoanalytical infrastructure for broad downstream applications such as antigen-specific immunotherapy development or T-cell receptor discovery.</p>","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149177951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Magnetic Bead-Based Electrochemical Immunoassay for Human Immunodeficiency Virus Type 1 p24 Antigen Detection.","authors":"Thaisa A Baldo, Nicole Villarini, Bethany Unruh, Maxwell D Bridges, Brooke M Enney, Matthew Lynd, Alex J Rai, Brian J Geiss, David S Dandy, Charles S Henry","doi":"10.1021/acssensors.6c02479","DOIUrl":"https://doi.org/10.1021/acssensors.6c02479","url":null,"abstract":"<p><p>Early and sensitive detection of human immunodeficiency virus 1 (HIV-1) p24 antigen is crucial for identifying acute infection before seroconversion and monitoring low-level viremia. Here, we report a magnetic bead (MB)-based electrochemical immunoassay using stencil-printed carbon electrodes, systematically comparing streptavidin-, tosyl-, and N-hydroxysuccinimide-MBs for p24 detection. Tosyl-MBs achieved superior analytical performance with limits of detection of 19.4 pg/mL in tris-buffered saline with Tween 20, 24.3 pg/mL in media containing viral lysis buffer, and 8.8 pg/mL in human serum, demonstrating excellent matrix tolerance and reproducibility across the clinically relevant concentration range. The sandwich immunoassay employed optimized capture and horseradish peroxidase-conjugated detection antibodies with chronoamperometric readout using 3,3',5,5'-tetramethylbenzidine substrate at 0.0 V vs a silver pseudoreference electrode, enabling rapid immunocomplex quantification on magnet-retained beads with minimal sample handling. Tosyl-MBs provided the strongest concentration-dependent response across all matrices tested, with surface chemistry influencing antibody immobilization efficiency, nonspecific background signal, and p24 capture capacity. The platform demonstrated stability for at least 28 days under storage conditions and successfully distinguished inactivated HIV-1 samples from negative controls, thereby establishing tosyl-MB electrochemical immunoassays that are compatible with serum and other complex biological matrices. Further validation with clinical specimens, integration of simplified sample-processing steps, and implementation in portable instrumentation will be required to assess their potential for future point-of-care HIV diagnostics.</p>","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ordered Anti-Restacking Three-Dimensional Ti3C2Tx MXene Networks on Silicon Microcone Arrays via Template-Directed Assembly for Highly Efficient Room-Temperature Ammonia Sensing.","authors":"Ran Xiong, Xianwu Xu, Yuchao Zhao, Hongbo Wang, Bingjun Yu, Linmao Qian, Jun-Ho Jeong, Inkyu Park, Zhi-Jun Zhao","doi":"10.1021/acssensors.6c03505","DOIUrl":"https://doi.org/10.1021/acssensors.6c03505","url":null,"abstract":"<p><p>The realization of room-temperature, low-power chemiresistive ammonia (NH3) sensors is highly desirable yet remains a formidable challenge, primarily hindered by the high activation energy of conventional metal oxides and the severe nanosheet restacking of emerging 2D MXene. Here, we propose a morphology-templated assembly strategy to construct an antirestacking, highly accessible 3D Ti3C2Tx MXene sensing network using ordered silicon microcone arrays as 3D scaffolds. This architectural design effectively prevents the face-to-face self-assembly of 2D MXene sheets, establishing unobstructed vertical channels for rapid gas molecule transport and maximizing the exposure of active terminal sites. Consequently, the optimized room-temperature sensor delivers an exceptional gas-sensing performance, featuring a broad dynamic range (100-10,000 ppm) and a 10.2-fold response enhancement toward 10,000 ppm NH3 compared to the device without microcones. Moreover, the sensor exhibits rapid signaling kinetics (120 s), excellent selectivity, and durable reliability. This work offers a controllable three-dimensional Ti3C2Tx sensing-layer design for low-power, room-temperature NH3 leakage monitoring.</p>","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149177956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Repurposing Type III CRISPR-Cas as Modular Cellular RNA Biosensors.","authors":"Caglar Yildiz, Sarah de Roode, Jinane Elias, Arjan Tibbe, Raymond H J Staals","doi":"10.1021/acssensors.6c03012","DOIUrl":"https://doi.org/10.1021/acssensors.6c03012","url":null,"abstract":"<p><p>Over the past decade, CRISPR-Cas based biosensors have emerged as sensitive, specific and programmable platforms for nucleic acid detection, with applications ranging from diagnostic tools, environmental monitoring and various applications in fundamental research. The vast majority of these biosensors are currently limited to in vitro applications, highlighting the need for cellular platforms. Here, we provide a perspective on the potential of type III CRISPR-Cas systems as a platform for real-time RNA biosensing in living cells. We discuss the unique properties that distinguish type III from other CRISPR-Cas types, including their intrinsic cyclic oligoadenylate (cOA) signal amplification cascade, PAM-free RNA targeting and the extensive biochemical diversity of their downstream CARF and SAVED effector proteins. We outline the fundamental design principles of a genetically encoded type III cellular biosensor, comprising a programmable guide RNA, a multi-subunit sensing complex and a cOA-sensing effector protein capable of generating optical or electrochemical readout signals. A remaining challenge for type III cellular biosensors is the inherent cytotoxicity of canonical cOA-activated effectors. We propose several strategies to re-engineer these outputs towards non-cytotoxic reporter systems. While cellular biosensors present a natural route toward in vivo sensing, they face many challenges beyond the choice of the output signal and hardware strategy. We conclude that type III CRISPR-Cas is a promising platform for programmable real-time RNA sensing in living cells, utilizing its diverse modular effector outputs, representing a significant expansion of the CRISPR biosensor toolkit, while emphasizing appropriate deployment scenarios that enables full potential of these biosensors.</p>","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149177985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proton-Conduction-Mediated High-Performance Ethanol Sensing in a Ni3(HHTP)2/Nafion Composite at Room Temperature","authors":"Yiling Tan,Bingsheng Du,Liwen Yang,Guangying Zhou,Evans Kibet,Wei Hu,Yongcai Guo,Yong He","doi":"10.1021/acssensors.6c02656","DOIUrl":"https://doi.org/10.1021/acssensors.6c02656","url":null,"abstract":"Conductive metal–organic frameworks (c-MOFs) are promising chemiresistive sensing materials for selective gas detection; however, their practical deployment is hindered by insufficient selectivity and humidity-induced performance degradation, both of which stem from poorly understood molecular-level conduction mechanisms. Here, we address this gap by engineering a Nafion-functionalized Ni3(HHTP)2 composite that enables a mechanistic shift from electron-dominant to synergistic electron–proton conduction. Through systematic in situ fourier transform infrared spectroscopy (FTIR)/X-ray photoelectron spectroscopy (XPS) and electrochemical impedance spectroscopy (EIS), we elucidate that the sensing process depends on competitive adsorption between ethanol molecules and prehydrated hydronium ions at the composite interface, disrupting the hydrogen-bond network. The conductive Ni3(HHTP)2 framework ensures efficient electron transport, while Nafion’s microphase-separated structure confers dual molecular sieving and preconcentration effects for ethanol. The resulting sensor delivers a high response of 729% to 30 ppm ethanol at RT and 40% RH, exhibits remarkable selectivity, as evidenced by linear discriminant analysis (LDA) with a classification accuracy of 90.91%, and shows rapid kinetics and strong discrimination against common interferents. This work established a fundamental mechanistic framework for proton–electron co-conduction in c-MOFs, supported by in situ spectroscopy and electrochemical analysis. It presents a generalizable interface-modulation strategy for selective volatile organic compound (VOC) sensing under ambient conditions, showing promise for breath analysis applications and industrial safety monitoring.","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":"295 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149152031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI-Enhanced Wearable Glucose Sensors: From Intelligent Sensing to Closed-Loop Management of Diabetes","authors":"Bo Sun,Lim Lee Ling,Mohamad Sofian Bin Abu Talip,Shixun Zheng,Yifu Fu,Quanjin Ma,Fazliyatul Azwa Md Rezali,Cheng Cheng,Yilin Peng,Sharifah F. Wan Muhamad Hatta","doi":"10.1021/acssensors.6c02471","DOIUrl":"https://doi.org/10.1021/acssensors.6c02471","url":null,"abstract":"Wearable glucose sensors enable continuous monitoring of glycemic dynamics, yet their clinical utility is constrained by signal instability, physiological delay, and limited predictive capability. Artificial intelligence (AI) has been increasingly integrated to address these limitations. This review summarizes recent advances in AI-enhanced wearable glucose sensors, with a focus on the evolution of sensing technologies and the role of AI across three main aspects: calibration, glucose prediction, and wearable closed-loop control. In calibration, AI-based approaches for improving short-term signal reliability and compensating long-term drift are reviewed. In prediction, methods ranging from continuous glucose monitoring (CGM)-based forecasting to multimodal sensor fusion and noninvasive sensing are summarized, including both continuous glucose estimation and event-oriented detection of hypo- and hyperglycemia. The integration of sensing, prediction, and insulin delivery in wearable closed-loop artificial pancreas is also discussed. Finally, the remaining challenges and future directions are discussed, highlighting the potential of AI-enhanced wearable glucose sensors to support more reliable and integrated diabetes management.","PeriodicalId":24,"journal":{"name":"ACS Sensors","volume":"45 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149152029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}