Aquatic Toxicology最新文献

{"title":"A transcriptomics-based analysis of mechanisms involved in the neurobehavioral effects of 6PPD-quinone on early life stages of zebrafish","authors":"Xuchun Qiu ,&nbsp;Jie Tang ,&nbsp;Yibing Zhang ,&nbsp;Ming Li ,&nbsp;Kun Chen ,&nbsp;Yanhong Shi ,&nbsp;Xiangyang Wu","doi":"10.1016/j.aquatox.2024.107129","DOIUrl":"10.1016/j.aquatox.2024.107129","url":null,"abstract":"<div><div>As an emerging pollutant frequently detected in aquatic ecosystems, the toxicity of N-(1,3-dimethylbutyl)-N’-phenyl-p-phenylenediamine-quinone (6PPD-quinone) on fish has been confirmed, but insight into the mechanisms underlying those adverse effects is still limited. Thus, we exposed zebrafish embryos to 6PPD-quinone at 0, 0.25, 2.5, and 25 μg/L until 120 h post-fertilization (hpf), and investigated the variations in their development, behavior, monoamine neurotransmitter levels, and transcriptional profile. Exposure to 6PPD-quinone notably elevated the heart rate of zebrafish at 48 hpf (at 2.5 and 25 μg/L) and 72 hpf (at 0.25, 2.5, and 25 μg/L). In the dark-light transition test, the locomotor activity of zebrafish larvae exposed to 6PPD-quinone significantly increased, especially in the dark periods. Exposure to 6PPD-quinone also altered the dopamine level and its turnover in zebrafish, which exhibited significant correlations to their locomotor activity. RNA sequencing identified 394 differentially expressed genes (DEGs), most of which have the molecular function of binding and catalytic activity. Five DEGs were predicted as the key driver genes in the protein-protein interaction networks associated with circadian rhythm (i.e., <em>npas2</em>), protein processing in endoplasmic reticulum (i.e., <em>hsp90b1</em> and <em>pdia4</em>), and estrogen signaling pathway (i.e., <em>hsp90aa1.1</em> and <em>hsp90aa1.2</em>). Our findings provide more insights into mechanisms underlying the toxicity of 6PPD-quinone to teleosts and highlight the necessity to assess its potential risks to aquatic ecosystems.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"276 ","pages":"Article 107129"},"PeriodicalIF":4.1,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142491849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automated counting and classifying Daphnia magna using machine vision","authors":"Yang Ma ,&nbsp;Wenping Xiao ,&nbsp;Jinguo Wang ,&nbsp;Xiang Kuang ,&nbsp;Rongqin Mo ,&nbsp;Yanfang He ,&nbsp;Jianfeng Feng ,&nbsp;Hengling Wei ,&nbsp;Liwen Zheng ,&nbsp;Yufei Li ,&nbsp;Peixin Liu ,&nbsp;Hao He ,&nbsp;Yongbin He ,&nbsp;Lemin Chen ,&nbsp;Zhaojun Lin ,&nbsp;Xiaoming Fan","doi":"10.1016/j.aquatox.2024.107126","DOIUrl":"10.1016/j.aquatox.2024.107126","url":null,"abstract":"<div><div><em>Daphnia magna</em> (<em>D. magna</em>) is a model organism widely used in aquatic ecotoxicology research due to its sensitivity to environmental changes. The survival and reproduction rates of <em>D. magna</em> are easily affected by toxic environments. However, their small size, fragility, and transparency, especially in neonate stages, make them challenging to count accurately. Traditionally, counting adult and neonate <em>D. magna</em> relies on manual separation and visual observation, which is not only tedious but also prone to inaccuracies. Previous attempts to aid counting with optical sensors have faced issues such as inducing stress damage due to vertical movement and an inability to distinguish between adults and neonates. With the advancement of deep learning technologies, our study employs a simple light source culture device and utilizes the Mask2Former model to analyze <em>D. magna</em> against the background. Additionally, the U-Net model is used for comparative analysis. We also applied OpenCV technology for automatic counting of adult and neonate <em>D. magna</em>. The model's results were compared against manual counting performed by experienced technicians. Our approach achieves an average relative accuracy of 99.72 % for adult <em>D. magna</em> and 98.30 % for neonate. This method not only enhances counting accuracy but also provides a fast and reliable technique for studying the survival and reproduction rates of <em>D. magna</em> as a model organism.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"276 ","pages":"Article 107126"},"PeriodicalIF":4.1,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142491850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanopolystyrene and phoxim pollution: A threat to hepatopancreas toxicity in Chinese mitten crab (Eriocheir sinensis)","authors":"Mengting Huang ,&nbsp;Yuan Ma ,&nbsp;Shunli Che,&nbsp;Longteng Shen,&nbsp;Zhicheng Wan,&nbsp;Shiping Su,&nbsp;Shuquan Ding,&nbsp;Xilei Li","doi":"10.1016/j.aquatox.2024.107124","DOIUrl":"10.1016/j.aquatox.2024.107124","url":null,"abstract":"<div><div>Significant concerns have been raised by the widespread pollutants phoxim (PHO) and nanopolystyrene (NP) in the natural environment. This study evaluated the toxicity effects on the hepatopancreas of <em>Eriocheir sinensis</em> caused by NP and/or PHO at concentrations found in the environment. Subchronic exposure to NP and/or PHO triggered hepatopancreas histological damage within a 21-day exposure period. The NP, PHO, and co-exposure (NPO) groups exhibited fewer blister-like (B) cells, along with the appearance of vacuolation. Furthermore, these exposures induced impairment in the hepatic tubule mucus barrier and mechanical barrier, as evidenced by altered expression of oxidative stress-related genes, mucin-related genes, and TJ-related genes. Additionally, alterations in immunity-related genes and inflammatory cytokine genes expression were observed. The findings showed that hepatopancreas inflammation was caused by both individual and combined exposure to NP and PHO and that the inflammatory response was exacerbated by the co-exposure. The possible pathways of hepatopancreas toxicity were further investigated by transcriptomic analysis. Hepatopancreas inflammation was brought on by subchronic exposure to PHO and co-exposure; this inflammation was exacerbated by co-exposure and was backed by the activation of NF-κB signaling pathway via targeting-related genes. In summary, this research represents the initial documentation, to the best of our understanding of the detrimental effects of exposured to NP and/or PHO at levels found in the environment disrupt the hepatopancreas mucus and mechanical barrier in crustaceans, triggering inflammatory responses. These findings highlight the significance of NP and/or PHO pollution for hepatopancreas health.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"276 ","pages":"Article 107124"},"PeriodicalIF":4.1,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thyroid endocrine disruption effects of OBS in adult zebrafish and offspring after parental exposure at early life stage","authors":"Xiaohui Zhao,&nbsp;Yaxuan Liu,&nbsp;Dan Yang,&nbsp;Shasha Dong,&nbsp;Jianhui Xu,&nbsp;Xiaohui Li,&nbsp;Xiaoying Li,&nbsp;Guanghui Ding","doi":"10.1016/j.aquatox.2024.107125","DOIUrl":"10.1016/j.aquatox.2024.107125","url":null,"abstract":"<div><div>As an alternative to perfluorooctane sulfonate, sodium <em>p</em>-perfluorous nonenoxybenzene sulfonate (OBS) has been widely used and caused ubiquitous water pollution. However, its toxicity to aquatic organisms is still not well known. Therefore, in this study, parental zebrafish were exposed to OBS at environmentally relevant concentrations from ∼ 2 h post-fertilization to 21 days post-fertilization (dpf) in order to investigate the thyroid disrupting effects in F0 adults and F1 offspring. Histopathological changes, such as hyperplasia of thyroid follicular epithelia and colloidal depletion, were observed in F0 adults at 180 dpf. In F0 females, thyroxine (T4) levels were significantly reduced in 30 and 300 μg/L exposure groups, while triiodothyronine (T3) levels were significantly increased in 3 μg/L exposure group. For F0 males, significant increases of T4 and T3 levels were observed, revealing the sex-specific differences after the OBS exposure. The transcription levels of some key genes related to the hypothalamic-pituitary-thyroid (HPT) axis were significantly disrupted, which induced the thyroid endocrine disruption effects in adult zebrafish even after a prolonged recovery period. For F1 offspring, the thyroid hormone (TH) homeostasis was also altered as T4 and T3 levels in embryos/larvae exhibited similar changes as F0 females. The transcription levels of some key genes related to the HPT axis were also significantly dysregulated, suggesting the transgenerational thyroid disrupting effects of OBS in F1 offspring. In addition, the decreased swirl-escape rate was observed in F1 larvae, which could be caused by disrupting gene expressions related to the central nervous system development and be associated with the TH dyshomeostasis. Therefore, parental OBS exposure at early life stage resulted in thyroid endocrine disruption effects in both F0 adult zebrafish and F1 offspring, and caused the developmental neurotoxicity in F1 larvae.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"276 ","pages":"Article 107125"},"PeriodicalIF":4.1,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142454373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accumulation, biochemical responses and changes in the redox proteome promoted by Ag and Cd in the burrowing bivalve Scrobicularia plana","authors":"Ana María Herruzo-Ruiz ,&nbsp;Chiara Trombini ,&nbsp;Marta Sendra ,&nbsp;Carmen Michán ,&nbsp;Ignacio Moreno-Garrido ,&nbsp;José Alhama ,&nbsp;Julián Blasco","doi":"10.1016/j.aquatox.2024.107123","DOIUrl":"10.1016/j.aquatox.2024.107123","url":null,"abstract":"<div><div>Silver (Ag) and cadmium (Cd) are non-essential metals that, as a result of natural processes and human activities, reach the aquatic environment where they interact with biota inducing potential toxic effects. To determine the biological effects of these metals on the endobenthic bivalve <em>Scrobicularia plana</em>, specimens were exposed to Ag and Cd at two concentrations, 5 and 50 μg∙L^-1, for 7 days in a controlled microcosm system. The levels of the metals were measured in the seawater, sediments and clam tissues. The possible toxic biological effects of Ag and Cd were studied using a battery of biochemical biomarkers that are responsive to oxidative stress: superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), glutathione-S-transferase (GST) activities, and metallothioneins (MTs) and lipid peroxidation (LPO) levels. Since both metals have been linked to oxidative stress, redox modifications to proteins were studied by differential isotopic labelling of the oxidised and reduced forms of cysteines (Cys). An accumulation of metals was observed in the digestive gland and gills following exposure, together with the activation of enzyme activities (SOD for the Cd exposure; SOD, CAT, GST, and GR for the Ag exposure). The MT and LPO levels (after individual exposure to Ag and Cd) increased, which suggests the existence of antioxidant and detoxification processes to mitigate the toxic oxidative effects of both metals. The redox proteomic analysis identified 771 Cys-containing peptides (out of 514 proteins), of which 195 and 226 changed after exposure to Ag and Cd, respectively. Bioinformatics analysis showed that exposure to metal affects relevant functional pathways and biological processes in <em>S. plana,</em> such as: “cellular respiration” (Ag), “metabolism of amino acids” and “synthesis and degradation of proteins” (Ag and Cd), “carbohydrate metabolism” and “oxidative stress” (Cd). The proteomic approach implemented here is a powerful complement to conventional biochemical biomarkers, since it evaluates changes at the protein level in a high-throughput unbiased manner, thus providing a general appraisal of the biological responses altered by exposure to the contaminants.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"276 ","pages":"Article 107123"},"PeriodicalIF":4.1,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detrimental effects of glyphosate on muscle metabolism in grass carp (Ctenopharyngodon idellus)","authors":"Biao Yan ,&nbsp;Lijun Luo ,&nbsp;Yindan Zhang ,&nbsp;Jun Men ,&nbsp;Yongyong Guo ,&nbsp;Shengmin Wu ,&nbsp;Jian Han ,&nbsp;Bingsheng Zhou","doi":"10.1016/j.aquatox.2024.107122","DOIUrl":"10.1016/j.aquatox.2024.107122","url":null,"abstract":"<div><div>Glyphosate, a commonly used herbicide, has been associated with environmental pollution and potential health risks to aquatic organisms. This study investigated the effects of glyphosate on the muscle metabolism of grass carp (<em>Ctenopharyngodon idellus</em>) following exposure to environmentally relevant concentrations. Over a 14-day exposure period to varying glyphosate levels, significant disruptions were observed in antioxidant capacity and muscle health. These disruptions were evidenced by reductions in total antioxidant capacity (T-AOC), increases in malondialdehyde (MDA) levels, and decreases in activities of glutathione peroxidase (GSH-PX) and catalase (CAT). Furthermore, exposure to glyphosate resulted in a reduction of vitamin E content and an elevation of hormonal levels, suggesting the potential for endocrine disruption. Metabolomics analysis identified 605 distinct metabolites, with notable alterations in amino acid, carbohydrate, and nucleotide metabolism pathways. Specifically, arginine and glutathione metabolisms were severely impacted, with decreases in key amino acids such as glycine and glutathione at higher glyphosate concentrations. Nucleotide metabolism, particularly purine synthesis, was also significantly affected, with reduced levels of deoxyguanosine and other purine-related compounds. The study further investigated the origins of these differential metabolites using the MetOrigin platform, suggesting a potential involvement of the intestinal microbiota in the metabolic response to glyphosate. These findings highlight the multifaceted adverse effects of glyphosate on fish muscle, including oxidative stress and metabolic dysregulation, which may contribute to diminished muscle quality and health risks for aquatic organisms.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"276 ","pages":"Article 107122"},"PeriodicalIF":4.1,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142454355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aryl phosphate ester-induced pericardial edema in zebrafish embryos is influenced by the ionic composition of exposure media","authors":"John Hoang,&nbsp;Jenna Wiegand,&nbsp;Zoe Mersman,&nbsp;Kevin Michalicek,&nbsp;Nicholas Jimenez,&nbsp;David C. Volz","doi":"10.1016/j.aquatox.2024.107121","DOIUrl":"10.1016/j.aquatox.2024.107121","url":null,"abstract":"<div><div>Pericardial edema – fluid accumulation within the pericardium – is a frequently observed malformation in zebrafish embryo-based chemical toxicity screens. We recently discovered that the severity of triphenyl phosphate (TPHP)-induced pericardial edema was dependent on the ionic strength of exposure media. TPHP is an aryl phosphate ester (APE) widely used as a plasticizer and flame retardant. APEs are characterized by having one or more aryl groups bound to a phosphate center, with TPHP containing only unsubstituted aryl groups. Therefore, the objective of this study was to begin investigating whether, similar to TPHP, pericardial edema induced by other structurally related APEs is dependent on the ionic composition of exposure media. We first mined the peer-reviewed literature to identify other APEs that 1) induced pericardial edema in zebrafish embryos within a minimum of three peer-reviewed publications, and 2) demonstrated a statistically significant induction of pericardial edema in at least 70 % of the studies evaluated. Based on this meta-analysis, we identified four other APEs that caused pericardial edema in zebrafish embryos: isopropylated triphenyl phosphate (IPTPP), cresyl diphenyl phosphate (CDP), tricresyl phosphate (TMPP), and 2-ethylhexyl diphenyl phosphate (EDHPHP). Using TPHP as a positive control and pericardial edema as a readout, we developed concentration-response curves for all four APEs based on static exposure from 24 to 72 h post-fertilization (hpf). We then conducted co-exposures with <span>D</span>-Mannitol (an osmotic diuretic) and exposures within reverse osmosis (RO) water determine whether the ionic composition of exposure media mitigated APE-induced pericardial edema at 72 hpf. Using pericardial edema as an endpoint, the approximate EC₅₀s for TPHP (positive control), IPTPP, CDP, TMPP, and EDHPHP were 6.25, 3.125, 3.125, 25, and 100 µM, respectively, based on exposure from 24 to 72 hpf. Interestingly, similar to our findings with TPHP, co-exposure with <span>D</span>-Mannitol and exposure within ion-deficient water significantly mitigated IPTPP- CDP-, TMPP-, and EDHPHP-induced pericardial edema in zebrafish embryos, suggesting that chemically-induced pericardial edema may be 1) dependent on the ionic composition of exposure media and 2) driven by a disruption in osmoregulation across the embryonic epidermis. Therefore, similar to other assay parameters, our findings underscore the need to standardize the osmolarity of exposure media in order to minimize the potential for false positive/negative hits in zebrafish embryo-based chemical toxicity screens conducted around the world.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"276 ","pages":"Article 107121"},"PeriodicalIF":4.1,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fibrous microplastics in the environment: Sources, occurrence, impacts, and mitigation strategies","authors":"Shaochong Liu ,&nbsp;Sizhi Liu ,&nbsp;Xiangyang Xiao ,&nbsp;Lu Liu ,&nbsp;Willie Peijnenburg ,&nbsp;Yan Xu ,&nbsp;Yanhao Wang ,&nbsp;Yaqi Yu ,&nbsp;Lianzhen Li ,&nbsp;Xilin She","doi":"10.1016/j.aquatox.2024.107119","DOIUrl":"10.1016/j.aquatox.2024.107119","url":null,"abstract":"<div><div>Fibrous microplastics (FMPs), a unique class of microplastics, are increasingly recognized as a significant environmental threat due to their ubiquitous presence and potential risks to ecological and human health. This review provides a comprehensive overview of FMPs, including their sources, prevalence in various environmental media, and potential impacts. FMPs, which can be found in over 90 % of certain environmental samples, originate from a diverse range of sources, including synthetic textiles, landfill waste, industrial emissions, and atmospheric deposition. These persistent pollutants pose a threat to both terrestrial and marine ecosystems. Their insidious presence can lead to ingestion by organisms, potentially disrupting ecosystems and posing risks to human health. Addressing the challenge of FMPs requires a multi-faceted approach. Reducing the production and use of synthetic fibers, implementing effective waste management practices, and developing new technologies to remove FMPs from wastewater and the broader environment are all crucial components of the solution. However, further research is essential to fully understand the long-term implications of FMPs on ecosystems and human health, laying the foundation for the development of robust and effective mitigation strategies.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"276 ","pages":"Article 107119"},"PeriodicalIF":4.1,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142491851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Persistent effects of larval exposure to glyphosate in mangrove rivulus fish","authors":"Lauren E. Corrigan ,&nbsp;Jennifer K. Hellmann","doi":"10.1016/j.aquatox.2024.107120","DOIUrl":"10.1016/j.aquatox.2024.107120","url":null,"abstract":"<div><div>Glyphosate, a key ingredient in many herbicides, is increasingly present in aquatic systems due to agricultural runoff. High doses of glyphosate cause defects in organisms due to its ability to interfere with physiological processes as an endocrine disruptor. We used the mangrove rivulus fish (<em>Kryptolebias marmoratus</em>) to evaluate the effects of larval exposure to glyphosate on non-target species in aquatic environments. These fish produce genetically identical offspring, allowing us to evaluate phenotypic responses to toxicant exposure while controlling for genetics. We treated newly hatched larvae for 96 h with concentrations of glyphosate on the low and high end of what they would experience in the wild: control (0 mg/L), low (0.01 mg/L), and high (1.1 mg/L), and then measured behavior, morphology, and reproductive traits at 60 and 130 days. We predicted that these amphibious fish exposed to low, environmentally relevant doses would show adaptive emersion behavior to escape poor quality water conditions, and deficits in other traits would be greater with higher glyphosate dosages. We found that low doses (0.01 mg/L) of glyphosate led to lower anxiety (decreased thigmotaxis) and impaired jumping behaviors while high dose exposures to glyphosate resulted in lower activity and lower average egg yield per individual. None of these effects appeared to be adaptive at low or high doses of glyphosate. While deficits in reproductive output scaled with dosage, phenotypic effects were often dosage-specific for each trait. This study demonstrates that even environmentally relevant concentrations of herbicide may be harmful to aquatic organisms and have consequences that persist well into adulthood. Furthermore, given that environmentally relevant concentrations of glyphosate induced deficits in reproductive output, this suggests that glyphosate contamination in natural systems may have population level consequences.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"276 ","pages":"Article 107120"},"PeriodicalIF":4.1,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Tire Wear Particle on growth, extracellular polymeric substance production and oxidation stress of algae Chlorella vulgaris: performance and mechanism","authors":"Yangyang Yang ,&nbsp;Jiaqiang Liu ,&nbsp;Haoran Lu ,&nbsp;Jun Hou ,&nbsp;Xiulei Fan ,&nbsp;Qiang Liu ,&nbsp;Minglei Zhao ,&nbsp;Lingxiao Ren ,&nbsp;Guoxiang You","doi":"10.1016/j.aquatox.2024.107118","DOIUrl":"10.1016/j.aquatox.2024.107118","url":null,"abstract":"<div><div>Tire wear particles (TWP) represent a distinctive form of microplastics (MPs) that are widely distributed in aquatic ecosystems. However, the toxicity of various types of TWP on phytoplankton remain to be further explored. Thus, three different TWPs originating from replaced bicycle, car, and electro-mobile tire (marked as BTWP, CTWP, and ETWP) were selected and their long-term biological influences on <em>Chlorella vulgaris</em> were investigated. Results demonstrated TWPs showed a concentration-dependent growth promotion of <em>Chlorella vulgaris</em>, with a maximum promotion rate reached to 40.51% (10 mg/L, 10 d), 23.5% (80 mg/L, 12 d), and 28.7% (20 mg/L, 12 d) in the presence of BTWP, CTWP and ETWP, respectively. Meanwhile, TWPs could stimulate the secretion of EPS and induce oxidative stress. EPS analysis revealed the increase of polysaccharides could protect the cell from the direct contact with TWP particles. Moreover, the increased concentration of EPS also helps to induce the settlement of TWP and reduce the leachate release. The release of TWP into the environment could act as an accelerator for the growth of <em>Chlorella vulgaris</em>, which might further change the normal physicochemical behaviors of algae colony in aquatic system. Our findings provide new insights into the toxicity mechanism of TWPs on freshwater algae and valuable data on environmental risk assessment of TWPs.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"276 ","pages":"Article 107118"},"PeriodicalIF":4.1,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142418620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}