Aquatic Toxicology最新文献_第10页

Compilation and standardization of oil toxicity data on early life stages of fish to support population-level oil spill impact modeling 编制和标准化鱼类早期生命阶段的油毒性数据，以支持种群水平的溢油影响建模

IF 4.1 2区环境科学与生态学

Aquatic Toxicology Pub Date : 2025-07-02 DOI: 10.1016/j.aquatox.2025.107480

Sami Vikkula , Samu Mäntyniemi , Sakari Kuikka

{"title":"Compilation and standardization of oil toxicity data on early life stages of fish to support population-level oil spill impact modeling","authors":"Sami Vikkula , Samu Mäntyniemi , Sakari Kuikka","doi":"10.1016/j.aquatox.2025.107480","DOIUrl":"10.1016/j.aquatox.2025.107480","url":null,"abstract":"<div><div>The risk of oil spills has increased in recent years due to rising tanker traffic and the emergence of poorly maintained vessels. While the environmental impacts of oil spills are wide-ranging, their effects on fish populations remain contested, prompting the need for further research and the development of improved tools and methodologies for impact assessment. One complicating factor is the heterogeneity of existing laboratory exposure data, which hinders their usage in population-level oil spill impact assessment. This study addresses that gap by compiling a dataset from peer-reviewed laboratory exposure studies on the early life stages (ELS) of fish exposed to oil. Through a systematic literature review, we identified relevant studies and developed novel standardization methods to improve data comparability. These methods included converting diverse exposure metrics to a baseline polycyclic aromatic hydrocarbon (PAH) concentration metric, calculating the geometric mean and time-weighted average concentrations, and modeling missing control concentrations. The resulting dataset encompasses multiple fish species and oil types, as well as wide exposure time and PAH concentration ranges, in order to support impact assessments across diverse spill scenarios in fish population dynamics models. Although our methodology significantly increased the amount of usable data, the species and oil type coverage remained uneven, requiring model structures that accommodate information borrowing. We provide recommendations to improve future experimental reporting and suggest methodological extensions for the standardization methods. This study demonstrates how structured data compilation and standardization can cost-effectively expand the applicability of existing experimental data for oil spill impact assessment.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"286 ","pages":"Article 107480"},"PeriodicalIF":4.1,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144597542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanistic insights into microplastic-induced reproductive toxicity in aquatic organisms: A comprehensive review 微塑料诱导水生生物生殖毒性的机理综述

IF 4.1 2区环境科学与生态学

Aquatic Toxicology Pub Date : 2025-07-01 DOI: 10.1016/j.aquatox.2025.107478

A K M Munzurul Hasan , Md. Foysul Hossain , Minhaz Uddin , Muhammad Tariq Khan , Uddin Md Saif , Mohamed Hamed , Christopher J. Martyniuk , Douglas P. Chivers

{"title":"Mechanistic insights into microplastic-induced reproductive toxicity in aquatic organisms: A comprehensive review","authors":"A K M Munzurul Hasan , Md. Foysul Hossain , Minhaz Uddin , Muhammad Tariq Khan , Uddin Md Saif , Mohamed Hamed , Christopher J. Martyniuk , Douglas P. Chivers","doi":"10.1016/j.aquatox.2025.107478","DOIUrl":"10.1016/j.aquatox.2025.107478","url":null,"abstract":"<div><div>Microplastics (MPs) are widespread contaminants in aquatic ecosystems and pose significant threats to both organisms and the environment. Their small size, high surface area, and capacity to adsorb toxic chemicals allow MPs to infiltrate food webs, affecting organisms across trophic levels. This review explores the intricate mechanisms by which MPs induce reproductive and endocrine toxicity, focusing on their physical and chemical properties, bioaccumulation dynamics, and associated molecular pathways. MPs interfere with hormonal homeostasis, oxidative stress responses, and apoptotic pathways, leading to disruptions in the hypothalamic-pituitary-gonadal axis, impaired steroidogenesis, and gonadal dysfunction. These effects manifest as reduced fertility, altered gametogenesis, and multigenerational reproductive impairments across diverse aquatic taxa. Furthermore, MPs serve as carriers for endocrine-disrupting chemicals, compounding their adverse effects on organisms and aquatic biodiversity. Through a synthesis of recent research, this review identifies key signaling pathways, including MAPK, PI3K-AKT, mTOR, NF-κB, PPAR and NLRP3 inflammasome, that may play a role in MP-induced reproductive toxicity. The findings underscore the urgent need for advanced mitigation strategies, regulatory frameworks, and further research to combat the ecological consequences of MP pollution. Prioritizing targeted interventions is essential to safeguard aquatic biodiversity and ensure ecosystem resilience against the pervasive threat of MPs.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"286 ","pages":"Article 107478"},"PeriodicalIF":4.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144578405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vps34 knockdown attenuated AlNPs-induced neurodevelopmental toxicity in zebrafish larvae and adults by inhibiting mitophagy Vps34敲低可通过抑制线粒体自噬来减弱alnps诱导的斑马鱼幼鱼和成鱼的神经发育毒性

IF 4.1 2区环境科学与生态学

Aquatic Toxicology Pub Date : 2025-07-01 DOI: 10.1016/j.aquatox.2025.107479

Ying Zhang , Jinjin Zhao , Tao Huang , Xiaocheng Gao , Lan Zhang , Yanhong Wang , Xinyue Guo , Ling Zhang , Qiao Niu , Qinli Zhang

{"title":"Vps34 knockdown attenuated AlNPs-induced neurodevelopmental toxicity in zebrafish larvae and adults by inhibiting mitophagy","authors":"Ying Zhang , Jinjin Zhao , Tao Huang , Xiaocheng Gao , Lan Zhang , Yanhong Wang , Xinyue Guo , Ling Zhang , Qiao Niu , Qinli Zhang","doi":"10.1016/j.aquatox.2025.107479","DOIUrl":"10.1016/j.aquatox.2025.107479","url":null,"abstract":"<div><div>Nano-alumina (AlNPs) are susceptible to inducing neurotoxicity, mainly through excessive autophagy/mitophagy. Vacuolar protein sorting 34 (Vps34) is a target for modulating autophagy. This study aimed to investigate whether Vps34 knockdown could reduce AlNPs’ neurodevelopmental toxicity. Zebrafish embryos were exposed to 100 mg/L of 13 nm AlNPs and 2.5 mmol/L of 3-methyladenine (3MA) until 144 h post-fertilization (hpf) to assess their development, neurobehavior, oxidative stress, and the expression of autophagy-related gene. Vps34 was knocked down using 500 µL of morpholino oligonucleotide (MO) at 1 mM. Additionally, embryos were treated with control, negative control, Vps34 knockdown, AlNPs (100 mg/L), and AlNPs + Vps34 knockdown. Evaluations included developmental parameters, locomotor activity, oxidative stress, autophagy/mitophagy gene expression, and neuronal cell counts at 144 hpf. Long-term effects were assessed up to 90 dpf, including locomotor activity, mitophagy-related genes expression, and ultrastructural analysis. The findings showed that 3MA effectively counteracted AlNPs-induced developmental stunting at 24 hpf, neurobehavioral impairments, oxidative damage, and upregulation of autophagy-related Beclin1, Vps34, and LC3II genes in larvae. AlNPs significantly elevated Vps34 gene expression in zebrafish. Additionally, Vps34 knockdown alleviated AlNPs-induced developmental retardation at 24 hpf, locomotor deficits, oxidative damage, neuronal loss, and abnormal expression of autophagy/mitophagy-related genes and P62 protein levels. Vps34 knockdown ameliorated AlNPs’ early developmental retardation and neurobehavioral deficits in zebrafish larvae and adults by reducing mitophagy. These findings suggest that Vps34 could be a promising therapeutic target for attenuating the neurotoxic effects of AlNPs.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"286 ","pages":"Article 107479"},"PeriodicalIF":4.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144563553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multigenerational effects of metals accumulate over three generations in the amphibian-killing fungus (Batrachochytrium dendrobatidis) 金属的多代效应在两栖类杀伤真菌（Batrachochytrium dendroatidis）中累积超过三代。

IF 4.1 2区环境科学与生态学

Aquatic Toxicology Pub Date : 2025-06-30 DOI: 10.1016/j.aquatox.2025.107476

Milad Esmaeilbeigi , Richard P. Duncan , Simon Clulow , Tariq Ezaz , Ben J. Kefford

{"title":"Multigenerational effects of metals accumulate over three generations in the amphibian-killing fungus (Batrachochytrium dendrobatidis)","authors":"Milad Esmaeilbeigi , Richard P. Duncan , Simon Clulow , Tariq Ezaz , Ben J. Kefford","doi":"10.1016/j.aquatox.2025.107476","DOIUrl":"10.1016/j.aquatox.2025.107476","url":null,"abstract":"<div><div>Exposure experiments within a single generation assess organisms’ sensitivity to pollutants but don't reveal long-term effects over multiple generations. We studied the multigenerational effects (MGEs) of copper (Cu), zinc (Zn), and their combination (Cu+Zn) on the amphibian-killing fungus <em>Batrachochytrium dendrobatidis</em> (Bd) over three generations. Our goal was to determine if Bd’s sensitivity to metals changes with continuous exposure, which should affect its long-term performance at metal-polluted sites. We conducted two experiments: (1) exposing three generations (F0-F2) of Bd to fixed, environmentally relevant metal concentrations, and (2) assessing how first-generation (F0) exposure influenced Bd’s response to varying metal concentrations in F1, including no exposure to metals. Experiment 2 allowed us to estimate transgenerational plasticity (TGP), the extent to which F0 exposure influenced offspring performance without metals. We measured Bd’s population growth rate, and the numbers of live zoospores, sporangia, and colonies. Continuous exposure to Cu and Zn led to a progressive decline in Bd performance over three generations, indicating accumulating negative effects. TGP was evident, with F0 metal exposure causing a decline in F1 performance without metals. TGP explained 20–80 % of the decline in population growth rate across generations with continuous metal exposure. Our findings suggest that continuous exposure to elevated Cu and Zn levels negatively impacts Bd, indicating that metal-polluted sites could serve as disease refugia for Bd-susceptible amphibians.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"286 ","pages":"Article 107476"},"PeriodicalIF":4.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144534426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of micro- and nano-plastics on marine organisms under environmentally relevant conditions 微塑料和纳米塑料在环境相关条件下对海洋生物的影响

IF 4.1 2区环境科学与生态学

Aquatic Toxicology Pub Date : 2025-06-30 DOI: 10.1016/j.aquatox.2025.107475

Ruirui Wang , Hongmei Tan , Xiaochen Huang , Jianjun Wang , Wenli Su , Farhana Maqbool , Lu Liu , Yuanshuo Ma , Meng Wang , Zhuomiao Liu , Xia Liu , Yanhui Dai , Tongtao Yue , Zhenyu Wang , Jian Zhao

{"title":"Impact of micro- and nano-plastics on marine organisms under environmentally relevant conditions","authors":"Ruirui Wang , Hongmei Tan , Xiaochen Huang , Jianjun Wang , Wenli Su , Farhana Maqbool , Lu Liu , Yuanshuo Ma , Meng Wang , Zhuomiao Liu , Xia Liu , Yanhui Dai , Tongtao Yue , Zhenyu Wang , Jian Zhao","doi":"10.1016/j.aquatox.2025.107475","DOIUrl":"10.1016/j.aquatox.2025.107475","url":null,"abstract":"<div><div>Micro- and nano-plastics (MNPs) pollution is a major issue of global concern, and the impacts of MNPs to marine organisms under environmentally relevant conditions were reviewed. Occurrence and distribution of both microplastics (MPs) and nanoplastics (NPs) in different marine environments were summarized based on current literature, showing that the maximal concentrations were 24.29 particles/L (Sanggou Bay) and 0.067 mg/L (polyethylene (PE), polyethylene terephthalate (PET), polystyrene (PS) in Antarctica sea ice), respectively. Impact of MNPs to different species of marine organisms (microalgae, crustaceans, gastropods and fish) at environmental concentrations were discussed. For microalgae, MPs at environmental concentrations (≤ 2 mg/L) showed two different short-term performances: no significant effect (52%) or significant inhibition (48%) on growth, while the long-term MPs stress could be alleviated through microalgae adaptation. Notably, the promotion of microalgae growth was observed after both short-term and long-term exposures of NPs. For high-trophic organisms (crustaceans, gastropods and fish), MNPs could induce physiological damage, and even cause reproductive toxicity. Environmental factors (e.g., dissolved organic matter, salinity and temperature) could alter the bioavailability and toxicity of MNPs, which were systematically introduced. Additionally, the impact of MNPs on the composition and diversity of marine communities were emphasized. Knowledge gaps were finally pointed out for better understanding the impact of MNPs under environmentally relevant conditions. This review provides useful information on the impact and risk of MNPs to marine organisms and the entire ecosystem.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"286 ","pages":"Article 107475"},"PeriodicalIF":4.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144570281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of ibuprofen on the behavior, histopathology, antioxidant system, DNA damage, and apoptosis of Asian freshwater clams (Corbicula fluminea) 布洛芬对亚洲淡水蛤（Corbicula fluinea）行为、组织病理学、抗氧化系统、DNA损伤和细胞凋亡的影响

IF 4.1 2区环境科学与生态学

Aquatic Toxicology Pub Date : 2025-06-28 DOI: 10.1016/j.aquatox.2025.107473

Yun-xia Hou , Xiang-sheng Hong , Shi-yin Tang , Wang Liu , Zhi-tong Li , Juan Wang , Sai-hong Yan , Jian-hui Qin , Jin-miao Zha

{"title":"Effect of ibuprofen on the behavior, histopathology, antioxidant system, DNA damage, and apoptosis of Asian freshwater clams (Corbicula fluminea)","authors":"Yun-xia Hou , Xiang-sheng Hong , Shi-yin Tang , Wang Liu , Zhi-tong Li , Juan Wang , Sai-hong Yan , Jian-hui Qin , Jin-miao Zha","doi":"10.1016/j.aquatox.2025.107473","DOIUrl":"10.1016/j.aquatox.2025.107473","url":null,"abstract":"<div><div>The accumulation of ibuprofen (IBU) in freshwater sediments poses significant risks to benthic bivalves, yet its chronic ecological impacts remain insufficiently studied. Here, Asian clams (<em>Corbicula fluminea</em>) were exposed to 0, 20, 200, and 2000 µg/L IBU for 28 days. The viscera were identified as the primary target organ for IBU toxicity, with bioconcentration factors (BCFs) ranging from 3.03–6.05 across treatments and a 1.3- to 3.3-fold increase in in digestive gland vacuolation damage. Chronic IBU exposure also induced neurotoxicity, evidenced by acetylcholinesterase inhibition, and potentially associated behavioral disturbances. Filtration and burrowing rates decreased significantly at 200 and 2000 µg/L, while escape rates increased, reflecting a trade-off between avoidance and burrowing under stress. At 20 µg/L, escape fluctuations were most pronounced, suggesting sub-threshold behavioral modulation. The trade-off between escape and burrowing highlights the adaptive yet costly responses of bivalves to pharmaceutical stress. Transcriptomic profiling demonstrated marked enrichment of apoptotic and pro-inflammatory pathways. Notably, while antioxidant defenses remained unaltered in clams, IBU exposure consistently upregulated COX-2 activity, with concomitant induction of genotoxic effects evidenced by DNA strand breakage and activation of caspase-9 mediated intrinsic apoptotic pathways. This work provides critical insights for managing pharmaceutical contamination in freshwater ecosystems and protecting benthic biodiversity and ecosystem functions.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"287 ","pages":"Article 107473"},"PeriodicalIF":4.1,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144515927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence of pollution, bioaccumulation, biomagnification, and toxic effects of per- and polyfluoroalkyl substances (PFAS) in aquatic ecosystems: A review 水生生态系统中全氟和多氟烷基物质（PFAS）的污染发生率、生物积累、生物放大和毒性效应综述

IF 4.1 2区环境科学与生态学

Aquatic Toxicology Pub Date : 2025-06-28 DOI: 10.1016/j.aquatox.2025.107469

Cunlong Wang , Jason T. Magnuson , Chunmiao Zheng , Wenhui Qiu

{"title":"Incidence of pollution, bioaccumulation, biomagnification, and toxic effects of per- and polyfluoroalkyl substances (PFAS) in aquatic ecosystems: A review","authors":"Cunlong Wang , Jason T. Magnuson , Chunmiao Zheng , Wenhui Qiu","doi":"10.1016/j.aquatox.2025.107469","DOIUrl":"10.1016/j.aquatox.2025.107469","url":null,"abstract":"<div><div>Per- and polyfluoroalkyl substances (PFAS) are persistently accumulated in both environmental media and biological systems, leading to significant toxicological effects. Although research on PFAS has expanded in recent years, systematic reviews on its concentration distribution in aquatic environments and biota, as well as its toxicological effects, remain scarce. Moreover, existing literature lacks systematic analyses of diverse aquatic environments and organisms. This review investigates the contamination levels of PFAS in aquatic environments. It also provides a systematic analysis of bioaccumulation in planktonic, swimming, and benthic organisms, including bioaccumulation factors (BAF), biomagnification factors (BMF), trophic magnification factors (TMF), and biota-sediment accumulation factors (BSAF), and evaluates the potential toxic effects on aquatic ecosystems. This study aims to provide theoretical support for the environmental regulation and management of PFAS. Additionally, it seeks to offer data references and potential research directions for future studies, thereby promoting the advancement of PFAS-related research and policy development.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"286 ","pages":"Article 107469"},"PeriodicalIF":4.1,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144515966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gut microbiota and mercury biotransformation: New perspectives on fish bioaccumulation in China 肠道菌群与汞生物转化：中国鱼类生物积累的新视角

IF 4.1 2区环境科学与生态学

Aquatic Toxicology Pub Date : 2025-06-27 DOI: 10.1016/j.aquatox.2025.107474

Xun Wang, Jia-Yi Lu, Junhao Fang

{"title":"Gut microbiota and mercury biotransformation: New perspectives on fish bioaccumulation in China","authors":"Xun Wang, Jia-Yi Lu, Junhao Fang","doi":"10.1016/j.aquatox.2025.107474","DOIUrl":"10.1016/j.aquatox.2025.107474","url":null,"abstract":"<div><div>China is the largest contributor to global mercury (Hg) emissions and the most predominant producer of fish. However, fish Hg concentrations in China are generally maintained at low levels, with localized “hot spots” in specific regions. The biotransformation of Hg, including methylation and demethylation, has been reported for over 50 years and is recognized as a key driver of Hg bioaccumulation in fish. This review provides an overview of Hg accumulation patterns of fish across diverse aquatic ecosystems in China, with focus on how regional heterogeneity in human activities influence Hg speciation, bioavailability, and trophic structure, ultimately contributing to localized “hot spots”. We further critically discuss the emerging role of gut microbiota in modulating Hg speciation and toxicity, and try to evaluate the quantitative significance of microbial biotransformation processes in determining spatial and interspecies differences in fish Hg levels in China. The findings highlight the gut microbiota as a critical mediator of Hg biotransformation, which influence its speciation, bioavailability, and ultimate accumulation in fish. Environmental Hg levels (diets and ambient water) and food composition appear to be critical factors affecting the gut microbial composition and biotransformation efficiency, which consequently determine Hg speciation and burdens. Particularly, geographic and species-specific variations in the abundance and activity of Hg-methylating and demethylating microbes contribute to the observed difference in Hg accumulation by fish. The review advances our understanding of Hg accumulation in China’s fish from the insight of biotransformation and highlights microbial pathways as key intervention targets for mitigating fish Hg contamination.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"286 ","pages":"Article 107474"},"PeriodicalIF":4.1,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144515960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microplastic pollution and amphibian health: Complex physiological effects of different microplastic types on juvenile Glandirana rugosa 微塑料污染与两栖动物健康：不同微塑料类型对腺蛙幼崽的复杂生理影响

IF 4.1 2区环境科学与生态学

Aquatic Toxicology Pub Date : 2025-06-27 DOI: 10.1016/j.aquatox.2025.107464

Jun-Kyu Park, Yuno Do

{"title":"Microplastic pollution and amphibian health: Complex physiological effects of different microplastic types on juvenile Glandirana rugosa","authors":"Jun-Kyu Park, Yuno Do","doi":"10.1016/j.aquatox.2025.107464","DOIUrl":"10.1016/j.aquatox.2025.107464","url":null,"abstract":"<div><div>Microplastics (MPs) are emerging contaminants; however, their effects on post-metamorphic amphibians remain unclear. Therefore, in this study, we aimed to examine the physiological and endocrine effects of MP on juvenile <em>Glandirana rugosa</em>, a semi-aquatic frog species, using polypropylene and high-density polyethylene. A cellulose-exposed group was also examined to differentiate between the physical and intrinsic effects of MPs. Mortality was significantly higher in the MP-exposed groups, particularly in the PE-exposed group. Elevated corticosterone levels indicated endocrine stress, suggesting that MPs act as physiological stressors. Based on the balance of the three antioxidant enzymes, evidence of oxidative stress was found in the MP and cellulose groups, indicating that particle ingestion triggered physiological responses. Intestinal elongation was observed in all particle-exposed groups, suggesting an adaptive mechanism to mitigate potential digestive impairments. MP accumulation patterns varied by polymer type, with polypropylene exhibiting a broad distribution. These findings highlight the physical and chemical risks of MPs and suggest that MPs exert physiological stress in addition to mechanical effects. Considering the increasing prevalence of MPs in natural habitats, their role in amphibian population decline warrants further attention. Collectively, our results underscore the importance of long-term ecological assessment and targeted conservation of amphibian populations.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"286 ","pages":"Article 107464"},"PeriodicalIF":4.1,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144515967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physiological, biochemical, and transcriptomic analysis revealed the toxicology and protective mechanisms of Scenedesmus obliquus in response to Phenanthrene 生理、生化和转录组学分析揭示了斜花菜对菲的毒理学反应和保护机制

IF 4.1 2区环境科学与生态学

Aquatic Toxicology Pub Date : 2025-06-24 DOI: 10.1016/j.aquatox.2025.107472

Yanyan Yang , Bingcong Li , Heyang Li , Huiyu Wen , Ronghao Qiao , Ming Li

{"title":"Physiological, biochemical, and transcriptomic analysis revealed the toxicology and protective mechanisms of Scenedesmus obliquus in response to Phenanthrene","authors":"Yanyan Yang , Bingcong Li , Heyang Li , Huiyu Wen , Ronghao Qiao , Ming Li","doi":"10.1016/j.aquatox.2025.107472","DOIUrl":"10.1016/j.aquatox.2025.107472","url":null,"abstract":"<div><div>Revealing the response of aquatic organisms to the toxicity of polycyclic aromatic hydrocarbons (PAHs) from the biological mechanism level is helpful to understanding the aquatic ecological risks of PAHs, and sequentially carrying out the necessary environmental management measures to reduce and eliminate the risks. In the current study, a comprehensive evaluation of the response and protective mechanisms of a widely used subject organism <em>Scenedesmus obliquus</em> to Phenanthrene (PHE) toxicity was conducted, integrating physiological, biochemical, and transcriptomic data. The results demonstrated that cell density, photosynthetic pigment content, and antioxidant enzyme activity in <em>S. obliquus</em> were increased under low concentrations (0.1 mg <em>L</em><sup>−1</sup>) of PHE stress. However, exposure to high concentrations (0.5–10 mg <em>L</em><sup>−1</sup>) of PHE resulted in a decrease in cell density and photosynthetic pigment content, along with significant increases in malondialdehyde (MDA) and reactive oxygen species (ROS) activity, indicating severe lipid peroxidation, cellular damage, and growth inhibition. Transcriptome analysis illustrated that most genes were up-regulated under 0.1 mgL<sup>−1</sup> PHE stress, particularly those involved in DNA replication, energy metabolism, and carbohydrate metabolism, suggesting that various metabolic pathways were activated to mitigate the effects of low-concentration PHE stress. Nevertheless, genes associated with the metabolism of energy, carbohydrates, amino acids, and lipids showed negligible expression changes under 10 mg <em>L</em><sup>−1</sup> PHE stress, indicating a suppression of the regulatory mechanisms in <em>S. obliquus</em>. Our findings provided a new insight into the toxicity mechanism of PHE on freshwater microalgae and valuable data for risk assessment of PHE.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"286 ","pages":"Article 107472"},"PeriodicalIF":4.1,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144491117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0