{"title":"Comparison of Language Development, Emotional and Behavioral Problems, Parental Attitude Characteristics, Parental Stress Level and Related Factors in Preschool Period, Between Preterm and Term-Born Children","authors":"Barış Güller, E. Yarcı, Ferhat Yaylacı","doi":"10.12956/tchd.1179344","DOIUrl":"https://doi.org/10.12956/tchd.1179344","url":null,"abstract":"Objective: We aimed to investigate language development, emotional and behavioral problems, parental attitudes,\u0000parental stress levels, and related factors in preschool period between children who were born preterm and term.\u0000Material and Methods: We included 176 children, of whom 90 were born preterm and 86 term, and their mothers.\u0000Mothers filled out the sociodemographic data form, Child Adjustment and Parent Efficacy Scale (CAPES-TR), Parenting\u0000Stress Index-Short Form (PSI-SF), and Parenting Styles and Dimensions Questionnaire – Short Version (PSDQ) scales.\u0000Denver II Developmental Screening Test (DDST) and Test of Early Language Development - Third Edition (TELD-3) were\u0000applied to children.\u0000Results: The mean age was 37.97±3.62 months for the preterm children, and 38.77±3.28 months for the term\u0000children. The scores of preterm children were lower in the TELD-3 subtests. The rates of children with abnormal\u0000development regarding personal social development and language development were significantly higher in preterm\u0000children (p=0.007 for personal social development and <0.001 for language development, respectively). CAPES-TR\u0000emotional and behavioral problems scores were higher in preterm children. CAPES-TR Parental Self-Efficacy Subscale\u0000was lower in preterm children (p<0.001). PSI-SF total score and PSDQ permissive parenting subscale score were higher\u0000in mothers of preterm children (p=0.005 and p<0.001, respectively).The preterm-born children were more commonly\u0000diagnosed with language disorder and global developmental delay (p=0.006 and p=0.019, respectively). A positive\u0000correlation was found between the week of birth, maternal education level and monthly income level and TELD-3\u0000scores, DENVER personal social and language development level (p<0.050).\u0000Conclusion: Our study revealed closer follow-up is important for preterm children to plan special education support when\u0000it is necessary.","PeriodicalId":246612,"journal":{"name":"Turkish Journal of Pediatric Disease","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128403446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
İ. Eker, A. Bükülmez, Ayhan Pektaş, Yeter Düzenli Kar, Nilgun Eroglu, M. Çeleğen, Y. Şenol, Ayse Citak, Baran Gül, Begüm Soyalan, Deniz Durmuş, Melissa Karataş
{"title":"Can Platelet Mass Index Be Used as a Prognostic Marker in Children Diagnosed with Multisystem Inflammatory Syndrome Associated with Coronavirus?","authors":"İ. Eker, A. Bükülmez, Ayhan Pektaş, Yeter Düzenli Kar, Nilgun Eroglu, M. Çeleğen, Y. Şenol, Ayse Citak, Baran Gül, Begüm Soyalan, Deniz Durmuş, Melissa Karataş","doi":"10.12956/tchd.1180080","DOIUrl":"https://doi.org/10.12956/tchd.1180080","url":null,"abstract":"Objective: We’ve aimed at evaluating whether the platelet mass index (PMI) can be a prognostic marker for children diagnosed with MIS-C.\u0000Material and Methods: 31 children diagnosed with MIS-C and treated at our university hospital between March 2020 and November 2021 were included. Demographic data, clinical findings and laboratory values at the time of hospitalization, admission to the intensive care unit and duration of hospitalization were evaluated retrospectively. PMI of each patient at the time of hospitalization was calculated and recorded.\u0000Results: There was a statistically significant negative correlation between PMI and ferritin (r= -0.635, moderate, p<0.001), CRP (r= -0.377, weak, p= 0.036), and procalcitonin (r= -0.481, weak, p=0.006) levels. There was a statistically significant positive relationship between PMI and leukocyte count (r=0.367, weak, p=0.042) and lymphocyte count (r=0.384, weak, p=0.033). Median PMI values of the patients requiring intensive care (1701.35 fl/nl) were lower, compared to the median PMI values of the patients not requiring intensive care (2523.94 fl/nl), however, statistical results could not be reached due to the low (4 of 31) number of patients requiring intensive care. Median PMI values of the patients whose ferritin level was >400 ng/ml (1415.2; 533.4 – 3600.5) were statistically lower compared to the median PMI values of the patients whose ferritin level was ≤400 ng/ml (2705.7; 1395.2 – 9167.6).Conclusion: The findings in our study demonstrate that low PMI levels identified in children with MIS-C at the time of diagnosis may be with more severe clinical courses","PeriodicalId":246612,"journal":{"name":"Turkish Journal of Pediatric Disease","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123449470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of Risk Factors for Obesity in Children Aged 6-17 Years Where Obesity Reaches Peak","authors":"Onur Kaşli, A. Buluş, M. Koçak, Ugur Ufuk Isi̇n","doi":"10.12956/tchd.1130690","DOIUrl":"https://doi.org/10.12956/tchd.1130690","url":null,"abstract":"Objective: Obesity is an important health problem affecting 25-30% of children and adolescents. This study, it was aimed to determine the age intervals in which obesity reaches to peak incidence and risk factors playing role in the development obesity among children and adolescents aged 6-17 years who presented to pediatrics outpatient clinic of Ankara Keçiören Training and Research Hospital. \u0000Material and Methods: This cross-sectional study included 3.000 children and adolescents aged 6-17 years and their parents who presented with any reason to pediatrics outpatient clinic of Ankara Keçiören Training and Research Hospital between October, 2019 and December, 2019.\u0000Results: Obesity was detected in 21.4% of children while 78.6% were not obese. A significant correlation was detected between birth weight and obesity (p=0.001). A significant correlation was found between obesity and time spent for TV, computer and video games per day (p<0.001). The obesity was significantly decreased by increasing duration of physical activity. In the study, the obesity incidence was 1.77-folds (1.25-2.50) higher in children with obese mother and 2.01-folds (1.42-2.85) in children with obese father.\u0000Conclusion: The obesity incidence is progressively increasing in childhood as with other age groups. To prevent such increase, measures should be taken as early as possible. An adequate and balanced nutrition and physical activity are of important in prevention and treatment of obesity. Although primary goal is to achieve lifestyle modifications, pharmacotherapy or surgery may be attempted in the presence of severe obesity-related complications.","PeriodicalId":246612,"journal":{"name":"Turkish Journal of Pediatric Disease","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133871502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Merve Onat, E. Akçay, A. Demir, Ümran Gül Ayvalık Baydur, Z. Göker, G. Şenses Dinç, E. Çöp
{"title":"Clinical and sociodemographic characteristics of patients hospitalized in a child and adolescent psychiatry inpatient unit","authors":"Merve Onat, E. Akçay, A. Demir, Ümran Gül Ayvalık Baydur, Z. Göker, G. Şenses Dinç, E. Çöp","doi":"10.12956/tchd.1211443","DOIUrl":"https://doi.org/10.12956/tchd.1211443","url":null,"abstract":"Objective: In this study, it was aimed to examine the clinical and sociodemographic characteristics of patients hospitalized in Ankara City Hospital Child and Adolescent Psychiatry Inpatient Unit during the pandemic period.\u0000Material and Methods: Medical records of children and adolescents who were hospitalized in Ankara City Hospital Child and Adolescent Psychiatry Inpatient Unit between March 2021 and March 2022 were retrospectively analyzed. Patients were evaluated in terms of sociodemographic characteristics, clinical diagnosis and treatment, duration of hospitalization, and Clinical Global Impression Scale (CGI) scores at admission and discharge. \u0000Results: In our study, the mean age of 132 cases (86 girls, 46 boys) was found 15.1±1.8 years. The main diagnoses of the subjects were 30.3% (n=40) major depressive disorder, 25% (n=33) psychotic disorder, 14.4% (n=19) eating disorders, and the remaining 30.3% (n=40) were other disorders. Comorbidity was found in 63.6% (n=84) of the cases. The presence of eating disorders, comorbidity and antidepressant use were found significantly higher in females. There was a significant differences in major depressive disorder (MDD), bipolar disorder (BD), psychotic disorder, eating disorder, conduct disorder, and post-traumatic stress disorder (PTSD) between admission and discharge CGI-Severity (CGI-S) scores. In addition, there was a significant difference between admission and discharge CGI side effects scores only for BD.\u0000Conclusion: In our study, major depressive disorder, psychotic disorder, and eating disorder were the most common diagnoses of cases hospitalized in inpatient unit. There was a comorbidity accompanying two out of every three cases. There are few child and adolescent psychiatry services in our country, and studies on this subject are scarce. It is thought that our study will contribute to the literature on child and adolescent psychiatry inpatient units.","PeriodicalId":246612,"journal":{"name":"Turkish Journal of Pediatric Disease","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125277435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Chronic Cough Etiologies in Children","authors":"Özge Yilmaz Topal","doi":"10.12956/tchd.1216596","DOIUrl":"https://doi.org/10.12956/tchd.1216596","url":null,"abstract":"Objective: Cough is one of the leading causes of hospitalization in children worldwide. It should be considered important because it can be a symptom of various serious diseases and affects the quality of life of the child. A differential diagnosis should be performed on all children with a chronic cough. This study aimed to determine the etiologies in patients evaluated for chronic cough. \u0000Material and Methods: The study included patients admitted to the pediatric immunology and allergy outpatient clinic, with the complaint of chronic cough between the ages of 0–18 years. Clinical and demographic characteristics of patients were recorded.\u0000Results: This study included 323 patients between the ages of 0-18years. The median age of the patients was 7 (interquartile range: 5-9.7) years. One hundred and forty five (45%) of the patients were female. One hundred seventy-nine (55.4%) patients had a family history of atopic diseases such as asthma and/or allergic rhinitis. The presence of aeroallergen sensitivity was demonstrated in 127 patients. One hundred and forty-four (44.6%) patients were diagnosed with asthma, 75 (23.2%) patients with wheezing, 54 (16.7%) patients with post-infectious cough, 43 (13.3%) patients with postnasal drip syndrome, 4 (1.2%) patients with gastroesophageal reflux, 2 (0.6%) patients with foreign body aspiration, and 1 (0.3%) patient with psychogenic cough. Moreover, two patients with asthma, and one patient with wheezing had reflux symptoms in addition to the diagnosis of asthma and wheezing. One patient was found to have a partial IgA deficiency, and 18 patients had hypogammaglobulinemia. Immunoglobulin replacement therapy was initiated for a patient with hypogammaglobulinemia. Of the 219 patients diagnosed with asthma or wheezing, 144 had an atopic disease in the family (p<0.001). It was found that one hundred and eighty-five patients (57.3%) had domestic smoke exposure. Furthermore, smoke exposure was observed in 58 (77.3%) of 75 patients under the age of 6 years who were followed up with the diagnosis of wheezing (p= 0.010).\u0000Conclusion: In our study, asthma, which is one of the most common causes of chronic cough in the literature, was found to be the most common cause. For a correct approach when making a differential diagnosis in pediatric patients presenting with chronic cough, the patient’s history, physical examination, laboratory tests, and risk factors should be evaluated as a whole with systematic evaluation.","PeriodicalId":246612,"journal":{"name":"Turkish Journal of Pediatric Disease","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127057877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Baby Sleep Position Practices and Sleep Environment","authors":"T. Çataklı, S. Şenel","doi":"10.12956/tchd.1199280","DOIUrl":"https://doi.org/10.12956/tchd.1199280","url":null,"abstract":"Objective: The aim of this current study was to determine mothers’ infant sleep position practices and their awareness of a safe sleeping environment.\u0000Material and Methods: This descriptive survey was conducted with 418 mothers who had infants aged 0-6 months and who agreed to participate in pediatric outpatient polyclinics of two hospitals. Data were collected between January-December 2020 via-structured questionnaires by face-to-face interview. \u0000Results: Of the 418 mothers; 28% placed their babies in the supine sleeping position, 59.6% used a pillow when they put their babies in bed and 76.8% used a soft mattress. 42.3% of mothers covered their babies’ faces during sleep; primary school graduate mothers were more intended on covering their babies’ faces than high school and university graduates (p<0.001). 4.1% of mothers smoked during pregnancy, 9.8% during the lactation period and 15.3% were exposed to household smoke. All of the mothers shared a room with their babies without sharing a bed. There was also a positive correlation between the number of prenatal visits of mothers and their preference to put their babies to sleep in the supine position (p=0.010). \u0000Conclusion: Most of the mothers placed their babies in a side sleeping position. Mothers’ avoiding sharing beds and smoking cigarettes and prone positioning their children at a very low frequency were pleasing measures. Mothers who had more prenatal visits were found to place their babies more in the supine sleep position. Increasing the awareness of healthcare providers and other secondary caregivers about a safe sleeping environment and baby sleep position during pre and postnatal visits would make right practices become widespread.","PeriodicalId":246612,"journal":{"name":"Turkish Journal of Pediatric Disease","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125689905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Patients with Chronic Cough Referred to Pediatric Pulmonology Outpatient Clinic","authors":"B. Özsezen","doi":"10.12956/tchd.1205598","DOIUrl":"https://doi.org/10.12956/tchd.1205598","url":null,"abstract":"Objective: A cough that lasts longer than four weeks in children is called chronic cough. The aim of this study is to determine the underlying causes of chronic cough. \u0000Material and Methods: Patients aged 0-18 years who were referred to Şanlıurfa Training and Research Hospital pediatric pulmonology outpatient clinic between 27 December 2021 and 30 June 2022 due to chronic cough were enrolled. Patients with known cystic fibrosis, primary ciliary dyskinesia, interstitial lung disease, asthma, bronchopulmonary dysplasia were excluded from the study. The “CHEST Guideline and Expert Panel Report” guideline was used in the approach to chronic cough. \u0000Results: 153 patients were included in this study. The most common causes of chronic cough were asthma (30.7%), protracted bacterial bronchitis (20.3%), and upper respiratory tract cough syndrome (11.1%). Wet cough was present in 60.8% of the patients with chronic cough and the most common diagnosis in patients with wet cough were protracted bacterial bronchitis (33.3%), pneumonia and other lung infections (17.2%) and bronchiectasis (12.9%). The most common diagnoses were asthma (68.3%), upper airway cough syndrome (6.7%), and natural recovery (6.7%) in patients with dry cough. Failure to thrive was more common in patients with wet cough than patients with dry cough (p<0.030) and fever, weight loss and desaturation were only present in patients with wet cough. \u0000Conclusion: The most common reasons are asthma, protracted bacterial bronchitis and upper airway cough syndrome. The differential diagnosis should be made by pediatricians based on specific cough pointers, careful physical examination and tests performed in line with the recommendations of the guidelines.","PeriodicalId":246612,"journal":{"name":"Turkish Journal of Pediatric Disease","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125225470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Efficacy of Erythrocyte Transfusion in Very Low Birth Weight Infants with Premature Anemia","authors":"A. Yazici, Betül Si̇yah, A. S. Özcan, S. Ünal","doi":"10.12956/tchd.1204367","DOIUrl":"https://doi.org/10.12956/tchd.1204367","url":null,"abstract":"Objective: This study aimed to determine the clinical efficacy of erythrocyte transfusion (ET) in premature infants.\u0000\u0000Material and Methods: Very low birth weight (VLBW) infants with gestational age (GA) < 32 weeks and/or birth weight (BW) <1500 g and hospitalized in neonatal intensive care unit (NICU) between 2012-2018 were retrospectively evaluated. ET was performed according to Ohls 2007 and Turkish Neonatalogy Society Blood Products Transfusion Guidelines. \u0000\u0000Results: 72 infants included in this study. Mean BW was 1325 g (680-2290 g), GA was 30 weeks (25-32), median postnatal age was 36.7±26.9 days (8-129), number of ET during hospitalization was 2±1.2 (1-6). There were no significant changes in mean heart rates (p=0.183) and median respiratory rates before and after ET (p=0.123). Weight gain (16 g/day-11 g/day) was statistically similar before and after ET (p=0.861). A significant decrease in apnea, non-invasive ventilation (NIV) and caffeine therapy requirements after ET was determined (p<0.001, p=0.016 and p=0.016). Serum lactate (2.9-1.5) levels were decreased by ET (p=0.017).\u0000\u0000Conclusion: Premature infants should closely follow-up for anemia and related symptoms during NICU stay. ET may help to decrease frequency of apnea of prematurity, requirements of caffeine therapy and NIV. ET improves tissue oxygenation in VLBW infants with anemia. Decision of ET should be made according to severity of symptoms, and should be performed according to international, national or local transfusion guidelines.","PeriodicalId":246612,"journal":{"name":"Turkish Journal of Pediatric Disease","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131844441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Burçak Kurucu, A. Fettah, Ş. Yeşil, Esra Fırat Oğuz, Ö. Erel, G. Şahin
{"title":"Dynamic Thiol-Disulfide Homeostasis in Children with Newly Diagnosed Iron Deficiency Anemia","authors":"Burçak Kurucu, A. Fettah, Ş. Yeşil, Esra Fırat Oğuz, Ö. Erel, G. Şahin","doi":"10.12956/tchd.1196564","DOIUrl":"https://doi.org/10.12956/tchd.1196564","url":null,"abstract":"Objective: Iron is an element, which is found in the structure of antioxidant enzymes and has an important role in the inactivation of reactive oxygen species. Disruption of oxidant-antioxidant balance may be playing a role in the pathogenesis of iron deficiency anemia (IDA). Dynamic thiol-disulfide homeostasis (DTDH) and serum ischemia-modified albumin (IMA) levels are important indicators of pro-oxidant/antioxidant status. In this study, we aimed to evaluate DTDH parameters and serum IMA levels in children with newly diagnosed IDA, who did not receive iron therapy.\u0000Material and Methods: Fifty patients diagnosed with IDA and 33 healthy age- and sex-matched control patients were included in the study. DTDH parameters and IMA levels of the patients and control groups were measured. The same parameters were also compared in patients with Hb<7 g/dl (profound IDA) (n:14/50, 28%) and Hb≥7 g/dl (mild-moderate IDA) (n: 36/50, 72%) in the IDA group. The relationship between DTDH parameters in these groups were investigated.\u0000Results: Native thiol, total thiol, native thiol/total thiol levels, constituting antioxidant capacity indicators, were found to be significantly lower in IDA patients; while oxidant disulfide, disulfide/native thiol, disulfide/total thiol, and IMA levels were found to be statistically higher compared to those in the control group (p<0.050). When DTDH parameters and IMA levels were examined; there was a positive correlation between antioxidant parameters and a negative correlation between oxidative parameters with hemoglobin and ferritin levels (p<0.050). Also, oxidative parameters were found to be much higher in profound IDA group than in the group with Hb>7 g/dl (p<0.050).\u0000Conclusion: In this study, increase in serum disulfide and IMA levels with the decrease in serum native thiol and total thiol levels indicated oxidative stress in IDA patients before treatment, compared to the control group. Evaluation of these indicators in children is important in predicting the toxicity due to IDA.","PeriodicalId":246612,"journal":{"name":"Turkish Journal of Pediatric Disease","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124302934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Characteristics and Possible Risk Factors of Epilepsy in Children with Cerebral Palsy: A Tertiary-Center Experience","authors":"D. Ardıçlı, Ö. Dedeoglu","doi":"10.12956/tchd.1213912","DOIUrl":"https://doi.org/10.12956/tchd.1213912","url":null,"abstract":"Objective: The aim of this study was to evaluate the clinical characteristics of children with cerebral palsy (CP) and to investigate possible risk factors and prognosis of epilepsy in children with cerebral palsy (CP) with a special emphasis on drug-resistant epilepsy (DRE). \u0000\u0000Materials and Methods: A total of 145 pediatric patients who were followed up with a diagnosis of CP between 2019 and 2022 were evaluated. Demographic features, prenatal/perinatal history, etiology and type of CP, degree of impairment in motor and cognitive functions, seizure type, neuroimaging, and electroencephalography (EEG) findings were obtained retrospectively from hospital records. The patients were divided into two groups: CP patients with epilepsy and patients without epilepsy. Study variables were compared between these two groups and also between DRE and controlled epilepsy groups. \u0000\u0000Results: There were 91 (63%) boys and 54 (37%) girls with a mean age of 11.1 ± 4.2 years (3-18 years). Epilepsy was present in 107 (73.7%) cases and 40.1% of them had refractory epilepsy. Epilepsy was most common in the tetraplegic form of CP (p=0.028). Term gestation, birth weight of ≥2500 g, and history of neonatal seizures were significantly higher in patients with epilepsy (p=0.03, 0.01, and 0.03, respectively). Children with DRE were more likely to have tetraplegic CP (50%) and severe intellectual disability (56%). \u0000\u0000Conclusion: Determination of potential risk factors is important in predicting the development of epilepsy in patients with CP, as it may provide closer follow-up of patients at high risk. Particular attention should be paid to the early identification and treatment of comorbid epilepsy in children with CP.","PeriodicalId":246612,"journal":{"name":"Turkish Journal of Pediatric Disease","volume":"79 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113971902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}