Wiener medizinische Wochenschrift最新文献

{"title":"Anticonvulsive treatment in autoimmune encephalitis: a systematic literature review.","authors":"Judith N Wagner","doi":"10.1007/s10354-022-00998-z","DOIUrl":"10.1007/s10354-022-00998-z","url":null,"abstract":"<p><strong>Background: </strong>Epileptic seizures are a common manifestation of autoimmune encephalitis (AIE). Immunosuppression (IT) is an efficient therapeutic approach, particularly in AIE associated with antibodies against extracellular structures. The role of antiseizure medication (ASM) is less clear. However, it may be beneficial in disease refractory to IT or in chronic post-AIE epilepsy.</p><p><strong>Methods: </strong>We conducted a systematic review assessing the PubMed and Cochrane databases to identify all reports on patients with epileptic seizures due to AIE in whom ASM was used and report it according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standards. We included case series (minimum 3 eligible patients), retrospective and prospective observational studies, and randomized controlled trials. The main outcome assessed was therapeutic efficacy of ASM. Secondary outcomes comprise number, type, and adverse effects of ASM. Descriptive statistics were used. The level of evidence was assessed according to the Centre for Evidence-Based Medicine.</p><p><strong>Results: </strong>We screened a total of 3371 studies and included 30 (7 prospective, 23 retrospective). The reports cover a total of 708 patients, the majority (72.5%) suffering from AIE with antibodies against extracellular structures. Type of AIE, seizure frequency, and number and type of ASM used were heterogenous. While most patients profited from IT and/or ASM, the effect of ASM could rarely be isolated. Nine studies report on patients who received ASM monotherapy or were on ASM for a relevant length of time before IT initiation or after IT failure. One study reports a significant association between seizure freedom and use of sodium channel inhibitors. However, levels of evidence were generally low.</p><p><strong>Conclusion: </strong>Few robust data exist on the particular efficacy of ASM in autoimmune epileptic seizures. While these patients generally seem to respond less well to ASM or surgical interventions, sodium channel blockers may have an additional benefit compared to other substances. However, levels of evidence are low and early IT remains the mainstay of AIE therapy. Future trials should address optimal ASM selection and dosing in AIE.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10536814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of whole-body vibration therapy on pain, functionality, postural stability, and proprioception in patients with subacute and chronic non-specific low back pain: a systematic review.","authors":"Franziska Remer, Mohammad Keilani, Philipp Kull, Richard Crevenna","doi":"10.1007/s10354-023-01026-4","DOIUrl":"https://doi.org/10.1007/s10354-023-01026-4","url":null,"abstract":"<p><strong>Introduction: </strong>Non-specific low back pain (NLBP) is a common and clinically significant condition with substantial socioeconomic implications. Whole-body vibration therapy (WBVT) has shown effectiveness in improving pain and sensorimotor function (e.g., in osteoporosis) in previous studies. However, studies had heterogeneous settings. The aim of this study was to assess the effects of WBVT on pain, function, proprioception, and postural stability in patients with subacute and chronic NLBP.</p><p><strong>Methods: </strong>A systematic literature search was conducted in the scientific databases PubMed, EMBASE, and PEDro (from inception until 17.05.2023). Only prospective controlled and uncontrolled studies were included. Outcome measures assessed were pain intensity, function (activities of daily living and physical function), proprioception, and postural stability.</p><p><strong>Results: </strong>A total of 12 original articles (n = 821) were included in the analysis. Ten of the studies were randomized controlled trials, one study had a crossover design, and one study had a one-group pre-post study design. The studies compared WBVT vs. no intervention, WBVT vs. basic physical therapy, WBVT vs. core stabilization exercises with and without respiratory resistance, WBVT vs. lumbar extension exercises, and WBVT vs. whole body electromyostimulation training. The treatment approaches varied in terms of duration (2-18 weeks), frequency (2-3 times per week, two applications with a 2-week break), vibration frequency (5-30 Hz), type of exercises (WBVT with or without static or dynamic exercises), and vibration direction (horizontal and vertical). Significant pain reduction was observed in all 10 studies that investigated pain levels. Significant improvement in daily activity function was reported in five of the six studies that investigated daily function, while improvement in physical function was observed in all four studies that investigated physical function. Improvement in proprioception was reported in all three studies that investigated proprioception, and significant improvement in postural stability was observed in four out of six studies that investigated postural stability. No adverse events or side effects related to WBVT were reported.</p><p><strong>Conclusion: </strong>The majority of the included studies demonstrated significant pain reduction, improvement in physical and daily functioning, and enhanced proprioception. Improvement in postural stability was less consistent. WBVT appears to be a safe and effective treatment modality for subacute and chronic NLBP when used within a multimodal approach. Future research should focus on standardized settings including assessment methods, treatment regimens, frequencies, and intensities.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138300183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of pulsed electromagnetic field therapy on pain and physical function in patients with non-specific low back pain: a systematic review.","authors":"Philipp Kull, Mohammad Keilani, Franziska Remer, Richard Crevenna","doi":"10.1007/s10354-023-01025-5","DOIUrl":"https://doi.org/10.1007/s10354-023-01025-5","url":null,"abstract":"<p><strong>Introduction: </strong>Non-specific low back pain is a common and clinically significant condition with substantial socioeconomic implications. Pulsed electromagnetic field (PEMF) therapy has shown benefits in pain reduction and improvement of physical function in patients with pain-associated disorders like osteoarthritis. However, studies had heterogeneous settings. The aim of this study was to assess the effects of PEMF on pain and function on patients with non-specific low back pain.</p><p><strong>Methods: </strong>A systematic literature search of randomized controlled trials in PubMed, MEDLINE, EMBASE, Cochrane Library, and PEDro was performed (from inception until 15/5/2023). Outcome measures assessed pain and function.</p><p><strong>Results: </strong>Nine randomized controlled trials with 420 participants (n = 420) were included. The studies compared PEMF vs. placebo-PEMF, PEMF and conventional physical therapy vs. conventional physical therapy alone, PEMF and conventional physical therapy vs. placebo-PEMF and conventional physical therapy, PEMF vs. high-intensity laser therapy (HILT) vs. conventional physical therapy, and osteopathic manipulative treatment (OMT) and PEMF vs. PEMF alone vs. placebo-PEMF vs. OMT alone. Five of the nine included studies showed statistically significant pain reduction and improvement in physical function in comparison to their control groups (p < 0.05). There was substantial heterogeneity among the groups of the study, with a wide range of duration (10-30 min), treatments per week (2-7/week), applied frequencies (3-50 Hz), and intensities (2mT-150mT). No serious adverse event had been reported in any study. The included studies showed solid methodological quality, with an overall score of 7.2 points according to the PEDro scale.</p><p><strong>Conclusion: </strong>PEMF therapy seems to be a safe and beneficial treatment option for non-specific low back pain, particularly if used as an addition to conventional physical therapy modalities. Future research should focus on standardized settings including assessment methods, treatment regimens, frequencies, and intensities.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138300184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Ergotism-a weed from Mesopotamia became an epidemic pathogen in Europe].","authors":"Heinz Flamm","doi":"10.1007/s10354-022-00960-z","DOIUrl":"10.1007/s10354-022-00960-z","url":null,"abstract":"<p><p>In Mesopotamian wheat fields rye grew as weed and after certain developments rye reached Europe and there became a cultivable plant and the dominant grain in certain regions. With the rye also its parasite, the Claviceps purpurea, reached Europe. This ascomycete infects particular rye grains and in its developmental cycle grows to sclerotia bigger than each grain. These forms, the so-called ergots, contain the poisonous ergotalcaloids. After their intake they produce two characteristic forms of ergotism.The clinical picture of the Ergotismus gangraenosus already before the knowledge of its origin, was known as \"Ignis sacer\", \"Anthony's Fire\" and \"Cold Gangrene\". In this non-febrile affection mostly of the limbs, the muscles were decomposed without bleeding and without pain and thereafter the bones detached. Sooner or later the patients died.The other form, Ergotismus convulsivus, mostly described in the German literature as \"Kriebelkrankheit\" (Crawly disease), begins with the sensation of running ants upon the limbs and continues with painful contractions of hands and feet. In many cases there is a loss of mind and language. Finally, death occurs.The intake of ergotalcaloids predominantly with products of rye flour and meal but also during processing the harvested rye are discussed as well as the \"Carry-over\" by meat and milk. It is stressed that the compliance with the legal Austrian and EU regulations for the maximum contents of sclerotia and ergotalcaloids resp. in products for human and animal nourishments only can be guaranteed by continuing the technics of separating the sclerotia and their parts.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40333625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wound healing at a Viennese medical school 200 years ago.","authors":"Roko Habek, Dubravko Habek","doi":"10.1007/s10354-022-00992-5","DOIUrl":"10.1007/s10354-022-00992-5","url":null,"abstract":"<p><p>This historical account is a departure from the oblivion of the historical circumstances surrounding the introduction of the open method of wound healing by Vincenz Kern, a Viennese professor of surgery in 1809, and which is still used today in most surgical professions. Thanks are also due to the famous Medical University of Vienna from where Kern ultimately established numerous schools throughout Europe, including Croatia, as a then part of the great Austrian Empire.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10768260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[O vos mendici medici. Criticism of medical doctors by Johannes Gregor Macer Szepsius (ca. 1530-after 1579)].","authors":"František Šimon, Florian Steger","doi":"10.1007/s10354-022-00997-0","DOIUrl":"10.1007/s10354-022-00997-0","url":null,"abstract":"<p><p>A relationship between literature and medicine has existed since antiquity. A physician often appears in the literary genre of satire as the representative of medicine and is the object of the satire. The barely known humanistic author Johannes Gregor Macer Szepsius (ca. 1530-nach 1579) was a humanist who sharply criticized the work and behavior of physicians. We have read, translated and analyzed the satirical verses from his comprehensive poetical work De vera gloria, On the true glory, with respect to content, structure and sources. According to this, physicians are characterized by conceit, ignorance and laziness and therapeutic ineptitude. The comparison with other satirical works shows that much of that which he accuses physicians of is repeated in the history of medicine. Some places are similar to the proverbs from Walter's collection of proverbs from the Middle Ages and others are similar to the invectives of Petrarch. Macer also levels criticism against physicians in his poem about the family tree of his friend Anton Schneeberger that appears in Schneeberger's work De bona valetudine militum conservanda liber.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9101309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Enchiridion medicinae (1573)-a short pharmaceutical manual compiled by Georg Henisch].","authors":"František Šimon, Florian Steger","doi":"10.1007/s10354-021-00869-z","DOIUrl":"10.1007/s10354-021-00869-z","url":null,"abstract":"<p><p>In 1573, Georg Henisch published a short pharmaceutical handbook, Enchiridion medicinae, which contains remedies for individual health problems, without making any further comments on the effects and method of use. However, this manual had a predecessor which was published in Paris in 1571 without mentioning the author. The text of both editions is practically identical, there are only minimal differences, but the second edition has been expanded to a foreword and final sections with some recipes. A comparison of the work with contemporary medical literature revealed that Enchiridion medicinae is a compilation of three works by other authors, De materia medicinali et compositione medicamentorum by G. Rondelet from 1556, a commentary by the French author Sebastien Coquillat Scipio on Galen's work Quos, quibus, quando purgare oporteat from 1553 and the book Lilium medicinae by Bernard de Gordon from 1550. Henisch probably acquired this compilation from 1571 as a young student in France, added some passages by Rendelet and passages from two others books, wrote a foreword which he signed with his name and published in Basel in 1573.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10354-021-00869-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39267953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Briefsammlung Wittelshöfer : Brief von Alois Czedik an Leopold Wittelshöfer vom 28.03.1871.","authors":"Andreas Hummel","doi":"10.1007/s10354-021-00852-8","DOIUrl":"10.1007/s10354-021-00852-8","url":null,"abstract":"","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39672438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"I would not wait for them to commit crime\": Cesare Lombroso's criminal anthropology in Croatia.","authors":"Martin Kuhar, Stella Fatović-Ferenčić","doi":"10.1007/s10354-021-00882-2","DOIUrl":"10.1007/s10354-021-00882-2","url":null,"abstract":"<p><p>Croatia is a Central European and Mediterranean country with a long maritime border with Italy. Throughout history, it was not only goods but also knowledge and medical practices that were exchanged over its borders. Following archival sources, individual informal networks, professional publications, daily newspapers, and public lectures, we aimed to present main channels by which Croatian intellectuals embraced Lombroso's criminal anthropology at the end of the 19th and the beginning of the 20th centuries. We illuminated the fact that the adoption of Cesare Lombroso's concepts stimulated the joint engagement and communication of medical and legal realms in Croatia. Our analysis exposed the traces of Lombroso's ideas within the reform of the penal code, thus influencing forensic psychiatric practice. We showed how those ideas were translated into policy, politically exploited, and pitched into discussions employing rhetorical techniques, which led to the stigmatization of certain groups of people, particularly patients suffering from epilepsy. Our results also showed that, contrary to other countries that formed Austria-Hungary, the discussions about Lombroso's criminology waned in Croatia after the First World War. We believe that our results can close the gap on this topic, adding the evidence about the spread and influence of Lombroso's concepts within Austria-Hungary in the analyzed period.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39467546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A historical delve into neurotrauma-focused critical care.","authors":"Mariam ElSaban, Gaurang Bhatt, Joanna Lee, Hiren Koshiya, Taha Mansoor, Tanya Amal, Rahul Kashyap","doi":"10.1007/s10354-022-01002-4","DOIUrl":"10.1007/s10354-022-01002-4","url":null,"abstract":"<p><p>Neurocritical care is a multidisciplinary field managing patients with a wide range of aliments. Specifically, neurotrauma is a rapidly growing field with increasing demands. The history of how neurotrauma management came to its current form has not been extensively explored before. Our review delves into the history, timeline, and noteworthy pioneers of neurotrauma-focused neurocritical care. We explore the historical development during early times, the 18th-20th centuries, and modern times, as well as warfare- and sports-related concussions. Research is ever growing in this budding field, with several promising innovations on the horizon.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10646513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}