Krisztina Racz, Andras Legner, Felix Böhme, Christian Sebesta
{"title":"[Gastric cancer].","authors":"Krisztina Racz, Andras Legner, Felix Böhme, Christian Sebesta","doi":"10.1007/s10354-023-01011-x","DOIUrl":"https://doi.org/10.1007/s10354-023-01011-x","url":null,"abstract":"<p><p>Gastric cancers are relativ commonly cancer types. The therapy options have changed in the last years as well in the surgery as in the oncology, it is worth to look at the etiology, diagnosis and therapy.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9905956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christian Sebesta, Alexandra Feichter, Flonza Selimi
{"title":"[Gastroenteropancreatic neuroendocrine tumors : (GEP-NENs)].","authors":"Christian Sebesta, Alexandra Feichter, Flonza Selimi","doi":"10.1007/s10354-022-00979-2","DOIUrl":"https://doi.org/10.1007/s10354-022-00979-2","url":null,"abstract":"<p><p>The entity of NENs represent a highly heterogenous group of malignancies that require a multidisciplinary approach during the treatment of patients. The following article aims to provide a concise overview of the current state of the art in diagnostics and therapy. One specific feature of G1/G2 NENs is that the indication for surgery is given even in metastatic settings. Specific details regarding the treatment of its various different subgroups need to be gathered from available guidelines or current clinical studies. The field of nuclear medicine offers promising options for diagnostics and therapy which needs further investigation.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9611467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Filip Medić, Antonio Ivan Miletić, Antonia Jakovčević, Dubravko Habek
{"title":"Papillary thyroid carcinoma within a mature cystic ovarian teratoma.","authors":"Filip Medić, Antonio Ivan Miletić, Antonia Jakovčević, Dubravko Habek","doi":"10.1007/s10354-023-01016-6","DOIUrl":"https://doi.org/10.1007/s10354-023-01016-6","url":null,"abstract":"<p><p>Mature cystic ovarian teratoma (dermoid cyst) is the most common germ cell tumor. Malignant tissue alteration in mature cystic teratoma is extremely rare, and malignant proliferation of thyroid tissue has been documented in only a few cases. This article presents a case of incidentally detected papillary microcarcinoma (PTMC) within a mature cystic ovarian teratoma. A 42-year-old patient with an ultrasound-suspected dermoid cyst was indicated for surgical treatment. Laparoscopic adnexectomy was performed, and a cystic-solid tumor 3.5 cm in diameter was removed entirely. Pathohistological analysis confirmed the diagnosis of a mature cystic teratoma with a PTMC 0.3 cm in diameter. Afterward, the patient underwent additional investigations with an oncologic radiotherapist and endocrinologist. Thyroid ultrasound, thyroglobulin serum levels, anti-thyroglobulin antibodies, thyroid scintigraphy, and abdominal positron emission tomography (PET) scan were performed to exclude disease dissemination. All results were with no findings of other disease seed/metastasis, and the patient will be followed up regularly by a gynecologist and endocrinologist.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9906480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Model for integration of a palliative medical concept into oncological treatment].","authors":"Gabriela Harrasser Exler, Annette Henry","doi":"10.1007/s10354-022-00995-2","DOIUrl":"https://doi.org/10.1007/s10354-022-00995-2","url":null,"abstract":"<p><p>Based on the case of a 55-year-old male patient, the challenge of integrating early palliative care is discussed. Although this is supported by various medical societies, the use of the word palliative in clinical work is often not simple, because it is still associated with the end of life. Primary palliative care is carried out by oncological teams. Secondary palliative care is utilized by specialized interprofessional teams. Some different models of implementing palliative care in oncological treatment are described and the use of the term supportive care instead of palliative care in some of them.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9542009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felix Böhme, Krisztina Racz, Christian Sebesta, Christian Sebesta
{"title":"[Esophageal Cancer].","authors":"Felix Böhme, Krisztina Racz, Christian Sebesta, Christian Sebesta","doi":"10.1007/s10354-022-00972-9","DOIUrl":"https://doi.org/10.1007/s10354-022-00972-9","url":null,"abstract":"<p><p>Esophageal cancer has poor prognosis and high letality. With yearly 600,000 new cases worldwide it ist he sixt most common cancer worldwide and the eight most deadly. Squamous cell carcinoma is more common in Africa and Asia, whereas incidence of adenocarcinoma ist increasing in Norh America and Europe. Riskfactors include alcohol, smoking, obesity, esophageal stenosis or achalasia. Currently there are no recommendations for prevention strategies or cancer screening. Symptoms in early stages are unspecific, so diagnosis is made late. Diagnostics include gastroscopy, CT, PET and endosonography. Therapeutic approaches are depending on disease stage and patients general condition. In early stages endoscopic resection is the treatment of choice. In higher stages theraoy consists of surgical resection and radiochemotherapy. Generalised stade ist treated with palliative systemic therapy and local interventions.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9549264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Doris Seitschek, Nina Sulz-Lehar, Christian Sebesta
{"title":"[Psychooncology-part of a comprehensive oncological treatment].","authors":"Doris Seitschek, Nina Sulz-Lehar, Christian Sebesta","doi":"10.1007/s10354-022-00968-5","DOIUrl":"https://doi.org/10.1007/s10354-022-00968-5","url":null,"abstract":"<p><p>This article provides a short overview of current issues in psychooncological care. Psychooncology, a relatively new interdisciplinary field, is meanwhile well estabilished as cancer diseases can lead to numerous psychological challenges and changes throughout the different stages of the disease. A significant proportion of cancer patients suffer during diagnosis and treatment from emotional distress. Main focus of psychological interventions is coping with fear, grief, pain, fatigue and how to improve quality of life under these circumstances. Psychological support has proven efficacious for helping patients as well as their families.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9929040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Steffi Hess, Martin Poryo, Ralf Böttger, Axel Franz, Daniel Klotz, Knud Linnemann, Torsten Ott, Johannes Pöschl, Michael Schroth, Anja Stein, Elisabeth Ralser, Heiko Reutter, Ulrich H Thome, Christian Wieg, Anne Ehrlich, Christian Ruckes, Stefan Wagenpfeil, Michael Zemlin, Cihan Papan, Arne Simon, Johannes Bay, Sascha Meyer
{"title":"Umbilical venous catheter- and peripherally inserted central catheter-associated complications in preterm infants with birth weight < 1250 g : Results from a survey in Austria and Germany.","authors":"Steffi Hess, Martin Poryo, Ralf Böttger, Axel Franz, Daniel Klotz, Knud Linnemann, Torsten Ott, Johannes Pöschl, Michael Schroth, Anja Stein, Elisabeth Ralser, Heiko Reutter, Ulrich H Thome, Christian Wieg, Anne Ehrlich, Christian Ruckes, Stefan Wagenpfeil, Michael Zemlin, Cihan Papan, Arne Simon, Johannes Bay, Sascha Meyer","doi":"10.1007/s10354-022-00952-z","DOIUrl":"10.1007/s10354-022-00952-z","url":null,"abstract":"<p><strong>Background and objective: </strong>Umbilical venous catheters (UVC) and peripherally inserted central catheters (PICC) are commonly used in preterm infants but have been associated with a number of serious complications. We performed a survey in Austria and Germany to assess the use of UVCs and PICCs in preterm infants with a birth weight < 1250 g and associated rates of catheter-related adverse events.</p><p><strong>Methods: </strong>Electronic survey of participating centers of the NeoVitaA trial. Main outcome parameter was the reported rates of UVC- and PICC-associated complications (infection, thrombosis, emboli, organ injury, arrhythmia, dislocation, miscellaneous).</p><p><strong>Results: </strong>In total, 20 neonatal intensive care units (NICU) providing maximal intensive care in Austria and Germany (level I) were contacted, with a senior neonatologist response rate of 12/20 (60%). The reported rates for UVC with a dwell time of 1-10 days were bacterial infection: 4.2 ± 3.4% (range 0-10%); thrombosis: 7.3 ± 7.1% (0-20%); emboli: 0.9 ± 2.0% (0-5%); organ injury: 1.1 ± 1.9% (0-5%); cardiac arrhythmia: 2.2 ± 2.5% (0-5%); and dislocation: 5.4 ± 8.7% (0-30%); and for PICCs with a dwell time of 1-14 days bacterial infection: 15.0 ± 3.4% (range 2.5-30%); thrombosis; 4.3 ± 3.5% (0-10%); emboli: 0.8 ± 1.6% (0-5%); organ injury: 1.5 ± 2.3% (0-5%); cardiac arrhythmia: 1.5 ± 2.3% (0-5%), and dislocation: 8.5 ± 4.6% (0-30%).</p><p><strong>Conclusion: </strong>The catheter-related complication rates reported in this survey differed between UVCs and PICCs and were higher than those reported in the literature. To generate more reliable data on this clinically important issue, we plan to perform a large prospective multicenter randomized controlled trial investigating the non-inferiority of a prolonged UVC dwell time (up to 10 days) against the early change (up to 5 days) to a PICC.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9362388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antimicrobial susceptibility and genotyping of microorganisms isolated from sputum culture of children with cystic fibrosis in an Iranian referral children's hospital.","authors":"Setareh Mamishi, Arezu Akhlaghi, Babak Pourakbari, Mohammadreza Modaresi, Mohammad Taghi Haghi Ashtiani, Reihaneh Hosseinpour Sadeghi, Rohola Shirzadi, Zohreh Shalchi, Shima Mahmoudi","doi":"10.1007/s10354-022-00970-x","DOIUrl":"https://doi.org/10.1007/s10354-022-00970-x","url":null,"abstract":"<p><strong>Background: </strong>Chronic bacterial infections of the airways are present in most patients with cystic fibrosis (CF). Although most pathogens are acquired from the environment, there is great evidence of patient-to-patient transmission. Therefore, evaluating the genetic variation of strains isolated from CF patients is recommended for the purpose of examining hospital infection.</p><p><strong>Aim: </strong>The aim of this study was to determine the antibiotic susceptibility pattern and genotyping of Staphylococcus aureus and Pseudomonas aeruginosa strains isolated from sputum samples of children with CF referred to a single pediatric CF center in Tehran, Iran.</p><p><strong>Methods: </strong>In this cross-sectional study, the antimicrobial susceptibility profiles of strains isolated from patients with CF during 1 year were determined. Pseudomonas aeruginosa and S. aureus isolates were genotyped using the random amplified polymorphic DNA polymerase chain reaction method and were analyzed using GelCompar II software.</p><p><strong>Results: </strong>Of 534 patients with CF, 384 had negative sputum cultures (72%), and 94 strains of P. aeruginosa (18%) and 53 strains of S. aureus (10%) were isolated. The mean age of the patients was 8.22 ± 5.7 years (range, 2 months to 18 years). The P. aeruginosa strains showed high sensitivity to ceftazidime (96%), piperacillin/tazobactam (96%), and imipenem (94%). All strains of S. aureus were susceptible to vancomycin, and 13% of the strains were methicillin-resistant S. aureus. High resistance to penicillin (92%) and erythromycin (88.5%) were reported. The results of P. aeruginosa genotyping revealed that there were six major clusters in this hospital. Also, based on the analysis of genotyping results, S. aureus strains were obtained from five clusters, most of which were located in cluster B1 (34 isolates, 64%).</p><p><strong>Conclusion: </strong>The results of this study show the possibility of strains being transferred from one part of the hospital to another (especially from the respiratory ward to other areas). Hence, high attention should be paid to the basic methods of preventing infection.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9720563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inferior vena cava thrombosis-rope ladder sign.","authors":"Sascha Meyer, Martin Poryo","doi":"10.1007/s10354-021-00886-y","DOIUrl":"https://doi.org/10.1007/s10354-021-00886-y","url":null,"abstract":"<p><p>Congenital heart disease comprises one of the largest groups of congenital defects, affecting approximately 1% of births. Advances in pre- and postoperative critical care treatment as well as surgery and interventional procedures have improved survival rates, but treatment and long-term care of children with complex congenital heart disease remains challenging, and is associated with a number of complications.Here, we report on a 17-month-old infant with congenital univentricular heart disease who devloped post-operatively inferior vena cava (IVC) thrombosis. IVC thrombosis was confirmed by a bedside contrast media study (X-ray) demonstrating collateral paravertebral circulation along the paravertebral sinuses bilaterally into the azygos and hemiazygos vein (\"rope ladder sign\"), with no contrast media detected in the IVC. The infant was subsequently started on aspirin and clopidogrel.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9422813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}