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[Gastrointestinal stromal tumors (GIST)]. 胃肠道间质瘤(GIST)。
IF 0.9
Wiener medizinische Wochenschrift Pub Date : 2023-06-01 DOI: 10.1007/s10354-022-00965-8
David Jaros, Boris Bozic, Christian Sebesta
{"title":"[Gastrointestinal stromal tumors (GIST)].","authors":"David Jaros,&nbsp;Boris Bozic,&nbsp;Christian Sebesta","doi":"10.1007/s10354-022-00965-8","DOIUrl":"https://doi.org/10.1007/s10354-022-00965-8","url":null,"abstract":"<p><p>Gastrointestinal stromal tumors (GIST) are rare tumors with a varying malignancy potential, most frequently located in the stomach and the small intestine. The median age at diagnosis is around 65 years. Standard treatment of localized disease is complete surgical resection. A GIST is generally resistant to conventional chemotherapy. Most GISTs harbor tyrosine kinase activating mutations in either the KIT or PDGFRA proto-oncogene. The standard treatment of locally advanced and metastatic GIST with such mutations is the tyrosine kinase inhibitor imatinib. In cases of progressive disease after successive treatment with imatinib, sunitinib, and regorafenib, a fourth-line therapy with ripretinib was recently approved. Approved in 2020, avapritinib is the first effective targeted therapy for advanced stage GIST harboring an imatinib-resistant PDGFRA D842V mutation.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":"173 9-10","pages":"201-205"},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9549244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
[The climate crisis as an ethical challenge]. [气候危机是一种道德挑战]。
IF 0.9
Wiener medizinische Wochenschrift Pub Date : 2023-06-01 DOI: 10.1007/s10354-022-00986-3
Lukas Kenner, Samuel Kenner, Barbara Prainsack, Peter Wallner, Kathrin Lemmerer, Lisbeth Weitensfelder, Hans-Peter Hutter
{"title":"[The climate crisis as an ethical challenge].","authors":"Lukas Kenner,&nbsp;Samuel Kenner,&nbsp;Barbara Prainsack,&nbsp;Peter Wallner,&nbsp;Kathrin Lemmerer,&nbsp;Lisbeth Weitensfelder,&nbsp;Hans-Peter Hutter","doi":"10.1007/s10354-022-00986-3","DOIUrl":"https://doi.org/10.1007/s10354-022-00986-3","url":null,"abstract":"<p><p>Climate change is a threat to health and social security of billions of people. Health and quality of life are increasingly affected in many ways due to the climate crisis. Rising global temperatures are resulting in increasingly frequent and severe extreme weather events, contributing to further increase in inequality, discrimination, and injustice overall and in health care specifically. Furthermore, climatic conditions are also becoming increasingly suitable for the transmission of infectious diseases and their spread into new regions. Socio-economically disadvantaged regions with weak health infrastructure (e.g. Global South) will be hardly able to cope without specific support. The overriding imperative is to achieve reductions in greenhouse gas emissions from transport, energy and food production at global, national and regional levels to mitigate negative health impacts. The 2015 Paris Agreement must also be seen as crucial health agreement. Our paper aims to highlight ethical aspects of climate change in the health sector.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":"173 9-10","pages":"232-238"},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9550030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Colorectal cancer]. (结肠癌)。
IF 0.9
Wiener medizinische Wochenschrift Pub Date : 2023-06-01 DOI: 10.1007/s10354-022-00975-6
Cheng Zhang, Margarete Stampfl-Mattersberger, Reinhard Ruckser, Christian Sebesta
{"title":"[Colorectal cancer].","authors":"Cheng Zhang,&nbsp;Margarete Stampfl-Mattersberger,&nbsp;Reinhard Ruckser,&nbsp;Christian Sebesta","doi":"10.1007/s10354-022-00975-6","DOIUrl":"https://doi.org/10.1007/s10354-022-00975-6","url":null,"abstract":"<p><p>Being one of the most common tumor entities worldwide, the colorectal carcinoma accounts for approximately 10% of all tumor-related deaths. With screening programs such as preventive colonoscopy, a decreasing incidence and mortality rate can be seen in the last decades. Many risk factors, which favor or prevent the development of colorectal carcinoma, can be traced back to lifestyle choices. Many patients with localized disease can be cured through tumor resection and adjuvant chemotherapy, in systemic disease, targeted therapy and immunotherapy have improved survival in the last years. This article aims to provide an overview on the basic epidemiologic, diagnostic and therapeutic principles of colorectal carcinoma, as well as a short excerpt of the newest therapeutic developments.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":"173 9-10","pages":"216-220"},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9557551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Gastroenteropancreatic neuroendocrine tumors : (GEP-NENs)]. [胃肠胰腺神经内分泌肿瘤：（GEP-NENs）]。
IF 0.9
Wiener medizinische Wochenschrift Pub Date : 2023-06-01 DOI: 10.1007/s10354-022-00979-2
Christian Sebesta, Alexandra Feichter, Flonza Selimi
{"title":"[Gastroenteropancreatic neuroendocrine tumors : (GEP-NENs)].","authors":"Christian Sebesta,&nbsp;Alexandra Feichter,&nbsp;Flonza Selimi","doi":"10.1007/s10354-022-00979-2","DOIUrl":"https://doi.org/10.1007/s10354-022-00979-2","url":null,"abstract":"<p><p>The entity of NENs represent a highly heterogenous group of malignancies that require a multidisciplinary approach during the treatment of patients. The following article aims to provide a concise overview of the current state of the art in diagnostics and therapy. One specific feature of G1/G2 NENs is that the indication for surgery is given even in metastatic settings. Specific details regarding the treatment of its various different subgroups need to be gathered from available guidelines or current clinical studies. The field of nuclear medicine offers promising options for diagnostics and therapy which needs further investigation.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":"173 9-10","pages":"221-226"},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9611467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Gastric cancer]. (胃癌)。
IF 0.9
Wiener medizinische Wochenschrift Pub Date : 2023-06-01 DOI: 10.1007/s10354-023-01011-x
Krisztina Racz, Andras Legner, Felix Böhme, Christian Sebesta
{"title":"[Gastric cancer].","authors":"Krisztina Racz,&nbsp;Andras Legner,&nbsp;Felix Böhme,&nbsp;Christian Sebesta","doi":"10.1007/s10354-023-01011-x","DOIUrl":"https://doi.org/10.1007/s10354-023-01011-x","url":null,"abstract":"<p><p>Gastric cancers are relativ commonly cancer types. The therapy options have changed in the last years as well in the surgery as in the oncology, it is worth to look at the etiology, diagnosis and therapy.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":"173 9-10","pages":"227-231"},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9905956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Papillary thyroid carcinoma within a mature cystic ovarian teratoma. 成熟囊性卵巢畸胎瘤内的乳头状甲状腺癌。
IF 0.9
Wiener medizinische Wochenschrift Pub Date : 2023-06-01 DOI: 10.1007/s10354-023-01016-6
Filip Medić, Antonio Ivan Miletić, Antonia Jakovčević, Dubravko Habek
{"title":"Papillary thyroid carcinoma within a mature cystic ovarian teratoma.","authors":"Filip Medić,&nbsp;Antonio Ivan Miletić,&nbsp;Antonia Jakovčević,&nbsp;Dubravko Habek","doi":"10.1007/s10354-023-01016-6","DOIUrl":"https://doi.org/10.1007/s10354-023-01016-6","url":null,"abstract":"<p><p>Mature cystic ovarian teratoma (dermoid cyst) is the most common germ cell tumor. Malignant tissue alteration in mature cystic teratoma is extremely rare, and malignant proliferation of thyroid tissue has been documented in only a few cases. This article presents a case of incidentally detected papillary microcarcinoma (PTMC) within a mature cystic ovarian teratoma. A 42-year-old patient with an ultrasound-suspected dermoid cyst was indicated for surgical treatment. Laparoscopic adnexectomy was performed, and a cystic-solid tumor 3.5 cm in diameter was removed entirely. Pathohistological analysis confirmed the diagnosis of a mature cystic teratoma with a PTMC 0.3 cm in diameter. Afterward, the patient underwent additional investigations with an oncologic radiotherapist and endocrinologist. Thyroid ultrasound, thyroglobulin serum levels, anti-thyroglobulin antibodies, thyroid scintigraphy, and abdominal positron emission tomography (PET) scan were performed to exclude disease dissemination. All results were with no findings of other disease seed/metastasis, and the patient will be followed up regularly by a gynecologist and endocrinologist.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":"173 9-10","pages":"245-247"},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9906480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Model for integration of a palliative medical concept into oncological treatment]. [将缓和医学概念融入肿瘤治疗的模式]。
IF 0.9
Wiener medizinische Wochenschrift Pub Date : 2023-06-01 DOI: 10.1007/s10354-022-00995-2
Gabriela Harrasser Exler, Annette Henry
{"title":"[Model for integration of a palliative medical concept into oncological treatment].","authors":"Gabriela Harrasser Exler,&nbsp;Annette Henry","doi":"10.1007/s10354-022-00995-2","DOIUrl":"https://doi.org/10.1007/s10354-022-00995-2","url":null,"abstract":"<p><p>Based on the case of a 55-year-old male patient, the challenge of integrating early palliative care is discussed. Although this is supported by various medical societies, the use of the word palliative in clinical work is often not simple, because it is still associated with the end of life. Primary palliative care is carried out by oncological teams. Secondary palliative care is utilized by specialized interprofessional teams. Some different models of implementing palliative care in oncological treatment are described and the use of the term supportive care instead of palliative care in some of them.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":"173 9-10","pages":"239-244"},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9542009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Esophageal Cancer]. 食道癌。
IF 0.9
Wiener medizinische Wochenschrift Pub Date : 2023-06-01 DOI: 10.1007/s10354-022-00972-9
Felix Böhme, Krisztina Racz, Christian Sebesta, Christian Sebesta
{"title":"[Esophageal Cancer].","authors":"Felix Böhme,&nbsp;Krisztina Racz,&nbsp;Christian Sebesta,&nbsp;Christian Sebesta","doi":"10.1007/s10354-022-00972-9","DOIUrl":"https://doi.org/10.1007/s10354-022-00972-9","url":null,"abstract":"<p><p>Esophageal cancer has poor prognosis and high letality. With yearly 600,000 new cases worldwide it ist he sixt most common cancer worldwide and the eight most deadly. Squamous cell carcinoma is more common in Africa and Asia, whereas incidence of adenocarcinoma ist increasing in Norh America and Europe. Riskfactors include alcohol, smoking, obesity, esophageal stenosis or achalasia. Currently there are no recommendations for prevention strategies or cancer screening. Symptoms in early stages are unspecific, so diagnosis is made late. Diagnostics include gastroscopy, CT, PET and endosonography. Therapeutic approaches are depending on disease stage and patients general condition. In early stages endoscopic resection is the treatment of choice. In higher stages theraoy consists of surgical resection and radiochemotherapy. Generalised stade ist treated with palliative systemic therapy and local interventions.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":"173 9-10","pages":"209-215"},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9549264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Psychooncology-part of a comprehensive oncological treatment]. 【心理肿瘤学——综合肿瘤治疗的一部分】。
IF 0.9
Wiener medizinische Wochenschrift Pub Date : 2023-06-01 DOI: 10.1007/s10354-022-00968-5
Doris Seitschek, Nina Sulz-Lehar, Christian Sebesta
{"title":"[Psychooncology-part of a comprehensive oncological treatment].","authors":"Doris Seitschek,&nbsp;Nina Sulz-Lehar,&nbsp;Christian Sebesta","doi":"10.1007/s10354-022-00968-5","DOIUrl":"https://doi.org/10.1007/s10354-022-00968-5","url":null,"abstract":"<p><p>This article provides a short overview of current issues in psychooncological care. Psychooncology, a relatively new interdisciplinary field, is meanwhile well estabilished as cancer diseases can lead to numerous psychological challenges and changes throughout the different stages of the disease. A significant proportion of cancer patients suffer during diagnosis and treatment from emotional distress. Main focus of psychological interventions is coping with fear, grief, pain, fatigue and how to improve quality of life under these circumstances. Psychological support has proven efficacious for helping patients as well as their families.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":"173 9-10","pages":"206-208"},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9929040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Editorial WMW 2021. WMW 2021社论。
IF 0.9
Wiener medizinische Wochenschrift Pub Date : 2023-06-01 DOI: 10.1007/s10354-022-00963-w
Christian Sebesta
{"title":"Editorial WMW 2021.","authors":"Christian Sebesta","doi":"10.1007/s10354-022-00963-w","DOIUrl":"https://doi.org/10.1007/s10354-022-00963-w","url":null,"abstract":"","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":"173 9-10","pages":"199-200"},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9574813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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