Elaheh Eslami, Hasan Siamian, Jamal Rezaei Orimi, Zahra Aghabeiglooei, Ebrahim Salimi-Sabour, Mohammad Amrollahi-Sharifabadi
{"title":"Pattern of bioterrorism in ancient times: lessons to be learned from the microbial and toxicological aspects.","authors":"Elaheh Eslami, Hasan Siamian, Jamal Rezaei Orimi, Zahra Aghabeiglooei, Ebrahim Salimi-Sabour, Mohammad Amrollahi-Sharifabadi","doi":"10.1007/s10354-023-01029-1","DOIUrl":"10.1007/s10354-023-01029-1","url":null,"abstract":"<p><p>The current research aimed to analyze the history of bioterrorism in antiquity and to adapt the data to modern medical knowledge. To this end, a thorough evaluation of the literature related to the ancient history of bioterrorism and modern data was done using the Web of Sciences, Science Direct, Scopus, PubMed, and Google Scholar. Results showed that knowledge of bioterrorism has existed since antiquity in different civilizations. Biological and toxicological agents were used as an instrument of legal execution, as a warfare tool in battles, or to eliminate political rivals across nations. Ancient people researched bioterrorism to apply it against enemies and at the same time provide countermeasures in favor of themselves and allies. Despite the existence of the principles of bioterrorism since ancient times, adaptation of the data to modern research can assist in planning countermeasure efforts, preventive actions, and treatments in the framework of modern counterterrorism medicine.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"288-298"},"PeriodicalIF":1.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The death of the Empress Elisabeth of Austria and Queen of Hungary-retold and reassessed with reconstruction of her autopsy.","authors":"Roland Sedivy","doi":"10.1007/s10354-024-01042-y","DOIUrl":"10.1007/s10354-024-01042-y","url":null,"abstract":"<p><p>In this publication 125 years after the violent death of the famous Empress Elisabeth (1837-1898) of Austria, known as Sisi, a modern evaluation as well as valuation will be presented. The day after her assassination by the young anarchist Luigi Lucheni using a file, a partial autopsy was performed to find out the exact cause of death-a pericardial tamponade. The complete translation of the autopsy report is part of this article, the intention being to avoid unclear wording and translation errors, which have often caused some confusion in the past. A pictorial illustration of the puncture canal will provide clarity through medical facts as to how Empress Elisabeth's death came about by correct pathological and anatomical description and, thus, counteract former interpretations.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"304-311"},"PeriodicalIF":1.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11424698/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140959727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduard Winter, Maria Teschler-Nicola, Karin Macfelda, Katrin Vohland
{"title":"The pathological anatomical collection of the Natural History Museum Vienna.","authors":"Eduard Winter, Maria Teschler-Nicola, Karin Macfelda, Katrin Vohland","doi":"10.1007/s10354-022-01001-5","DOIUrl":"10.1007/s10354-022-01001-5","url":null,"abstract":"<p><p>The pathological anatomical collection Vienna (Pathologisch-Anatomische Sammlung Wien; PASW) is a living and still growing research collection. It was established as early as 1796 as part of the Medical University of Vienna, acquired the status of an independent federal museum in 1971, and was assigned to the Natural History Museum Vienna in 2012. It houses a wide range of human wet and dry specimens and further objects, such as moulages, medical devices, microbiological and histological specimens, and a photo archive (approximately 50,000 objects), which, as a meaningful source, may contribute to disclosing not only aspects of the medical history and the development of corresponding museums in Vienna, but is also considered a collection of cultural and current scientific relevance, quite comparable to today's biobanks. Most of the tissue amassment represents wet organic specimens and human skeletons or skeletal elements representing, e.g., congenital and metabolic disorders, infectious diseases, injuries, neoplasms, or musculoskeletal diseases, basically collected as descriptive anatomical teaching aids. This article reviews the current medical issues on which research has been and is being conducted by including PASW specimens (hereby using the ICD-10 code), and the extent to and ethical conditions under which this important heritage could be used as a reference collection for clinical and bioanthropological (paleopathological and palaeoepidemiological) studies; finally, this article reflects on the value and future research prospects, taking into account different positions and the ongoing discussions in pathological anatomical human tissue collections.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"265-278"},"PeriodicalIF":1.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10660968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The trembling heart of the monarch-Insights into the heart condition of Emperor Maximilian II].","authors":"Tobias Heusinger, Michael Stolberg","doi":"10.1007/s10354-023-01022-8","DOIUrl":"10.1007/s10354-023-01022-8","url":null,"abstract":"<p><p>It has long been known in historical research that the Habsburg Emperor Maximilian II (1527-1576) suffered from heart complaints throughout his life. Numerous biographers mention this fact. His medical history and even the results of the autopsy of his body have been handed down; however, it has not been sufficiently investigated how Maximilian's physicians explained his heart condition, often referred to as \"tremor cordis\", and what causes and triggers they held responsible for this complaint in general and in the specific case of their famous patient. This article addresses these questions, primarily on the basis of a detailed consultation by the imperial personal physician Andrea Gallo, dating from 1555. Gallo's consilium, which has been ignored by scholares so far, first summarizes the state of knowledge on heart tremors at that time. It then turns to Maximilian's case and provides revealing insights into his mental state.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"299-303"},"PeriodicalIF":1.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11424730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41156834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Doris Weiss, Philipp Weber, Amélie Hampel, Julia Tittes, Wolfgang Weninger, Tamar Kinaciyan
{"title":"Diagnostic difficulties in pediatric annular dermatoses.","authors":"Doris Weiss, Philipp Weber, Amélie Hampel, Julia Tittes, Wolfgang Weninger, Tamar Kinaciyan","doi":"10.1007/s10354-023-01019-3","DOIUrl":"10.1007/s10354-023-01019-3","url":null,"abstract":"<p><p>The polymorphic presentation of annular dermatoses in the pediatric population renders them a diagnostic challenge to the clinician. They include various distinct disease entities that can be vaguely categorized according to the age of onset. Herein, we report on a young girl with clinical characteristics of Wells' syndrome, while histological findings favored the diagnosis of annular erythema of infancy (AEI). Although morphological and histological similarities do exist, AEI and eosinophilic annular erythema (EAE) of childhood are considered as distinct entities in the literature. Wells' syndrome (WS) is an eosinophilic dermatosis and histologically characterized by eosinophilic dermal infiltration with the hallmark feature of \"flame figures.\" Based on this case, we discuss and review the differential diagnoses of annular dermatoses in children.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"242-245"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11347483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10033708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diaper dermatitis-a narrative review of clinical presentation, subtypes, and treatment.","authors":"Anca Chiriac, Uwe Wollina","doi":"10.1007/s10354-023-01024-6","DOIUrl":"10.1007/s10354-023-01024-6","url":null,"abstract":"<p><p>Diaper dermatitis (DD) is an umbrella term with different clinical presentations, pathophysiology, treatments, and outcomes. The major subtypes include irritant contact dermatitis and candida-associated DD. In case of atypical presentation or unresponsiveness to treatment, other differential diagnoses should be considered. Although DD can occur at any age, it peaks in newborns and infants < 2 years of age. We will focus on this age group in our narrative review.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"246-256"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49682957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sascha Meyer, Steffi Hess, Martin Poryo, Cihan Papan, Arne Simon, Silvia Welcker, Anne Ehrlich, Christian Ruckes
{"title":"Study draft: \"UVC-You Will See\" study: longer vs. shorter umbilical venous catheter (UVC) dwell time (6-10 vs. 1-5 days) in very premature infants with birth weight < 1250 g and/or gestational age < 30 weeks.","authors":"Sascha Meyer, Steffi Hess, Martin Poryo, Cihan Papan, Arne Simon, Silvia Welcker, Anne Ehrlich, Christian Ruckes","doi":"10.1007/s10354-024-01047-7","DOIUrl":"10.1007/s10354-024-01047-7","url":null,"abstract":"<p><strong>Background: </strong>Umbilical venous catheters (UVCs) are often used in preterm infants. Their use is associated with complications (infections, clot formation, organ injury). Very preterm infants with acquired bloodstream infection are at a higher risk for death and important morbidities (e.g., adverse neurodevelopmental outcomes). It is standard clinical practice to remove UVCs in the first days of life. Replacement of intravenous access is often performed using percutaneously inserted central catheters (PICCs). It is unclear whether serial central line use affects the rates of catheter-related complications.</p><p><strong>Methods: </strong>A multicenter randomized controlled trial (random group assignment) was performed in 562 very premature (gestational age < 30 weeks) and/or very low birth weight infants (< 1250 g) requiring an UVC for administration of parenteral nutrition and/or drugs. Group allocation was random.</p><p><strong>Hypothesis: </strong>A UVC dwell time of 6-10 days (281 infants) is not associated with an increased rate of central venous catheter (UVC, PICC)-related complications compared to 1-5 days (281 infants), and a longer UVC dwell time will significantly reduce the number of painful, invasive procedures associated with the need for vascular access as well as radiation exposure, use of antibiotics, and medical costs.</p><p><strong>Primary outcome parameter: </strong>The number of catheter-related bloodstream infections and/or catheter-related thromboses and/or catheter-associated organ injuries related to the use of UVC/PICC was the primary outcome.</p><p><strong>Conclusion: </strong>Extending the UVC dwell time may significantly reduce the number of painful invasive procedures, with the potential to positively impact not only long-term pain perception but also important social competencies (attention, learning, and behavior). Thus, the \"UVC-You Will See\" study has the potential to substantially change current neonatal intensive care practice.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"217-224"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11347460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141311941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Petra Rižnik, Tina Kamhi Trop, Martina Klemenak, Tomaž Krenčnik, Tanja Milanič-Koron, Eva Miler Mojškerc, Tatjana Pavlin, Tina Požek Šavs, Janez Zupančič, Jernej Dolinšek
{"title":"Insights into coeliac disease diagnosis: a 2021-2023 overview of diagnostic approach and delays in children in Slovenia.","authors":"Petra Rižnik, Tina Kamhi Trop, Martina Klemenak, Tomaž Krenčnik, Tanja Milanič-Koron, Eva Miler Mojškerc, Tatjana Pavlin, Tina Požek Šavs, Janez Zupančič, Jernej Dolinšek","doi":"10.1007/s10354-024-01045-9","DOIUrl":"10.1007/s10354-024-01045-9","url":null,"abstract":"<p><strong>Introduction: </strong>Over the past decade, the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) proposed the option of diagnosing coeliac disease (CD) in children without duodenal biopsy. The aim of our study was to assess the diagnostic approach in newly diagnosed children with CD in Slovenia.</p><p><strong>Methods: </strong>In this prospective study, Slovenian paediatric gastroenterologists were invited to provide medical records of children under 19 years diagnosed with CD from March 2021 to October 2023. The analysis focused on tissue transglutaminase antibody (TGA) levels at diagnosis, diagnostic approach, adherence to ESPGHAN CD guidelines and diagnostic delays.</p><p><strong>Results: </strong>Data from 160 newly diagnosed CD patients (61.9% female; median age 8 years; 16.9% asymptomatic) were available for the analysis. No-biopsy approach was used in 65% (N = 104) of children and the majority (N = 101) fulfilled all the criteria for the no-biopsy approach. Of 56 children diagnosed using duodenal biopsy, a further 10 (17.8%) would have also been eligible for the no-biopsy approach based on the very high levels of TGA. Median diagnostic delay from first symptoms to confirmation of diagnosis was 6 months (min 0 months, max 87 months). Use of the no-biopsy approach has risen significantly since 2016 (37.8% vs. 65.0%; p = 0.001) and diagnostic delays have shortened (6 vs. 7 months; p < 0.05).</p><p><strong>Conclusion: </strong>This prospective study highlights the frequent use of a no-biopsy approach for diagnosing CD in children in Slovenia, showing large adherence to ESPGHAN guidelines. Also, diagnostic delays have shortened over recent years, likely due to various awareness-raising projects on CD conducted during this period.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"257-261"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11347456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sascha Meyer, Sarah Ruffing, Martina Geipel, Martin Poryo, Alexander Larsen, Sogand Nemat
{"title":"Something is up in the air: pneumothorax and pneumopericardium in a 29-week preterm infant.","authors":"Sascha Meyer, Sarah Ruffing, Martina Geipel, Martin Poryo, Alexander Larsen, Sogand Nemat","doi":"10.1007/s10354-023-01021-9","DOIUrl":"10.1007/s10354-023-01021-9","url":null,"abstract":"<p><p>This report highlights the early and unusual detection of a pneumopericardium by echocardiography prior to potential development of cardiocirculatory compromise. It is important to consider pneumopericardium into the differential diagnosis when difficulties arise in the visualization of the heart by conventional echocardiography. Pneumopericardium is associated with a high mortality rate and may be effectively treated by immediate insertion of a pericardial catheter.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"211-212"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11347491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41162382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xenia Frank, Sascha Meyer, Amélie Hufnagel-Schmude, Anton Dunsche, Uwe Spetzger, Albert Augustin, Paul Vöhringer
{"title":"[Invasive ENT infections in immunocompetent schoolchildren in the winter half year 2022/23 : A case series].","authors":"Xenia Frank, Sascha Meyer, Amélie Hufnagel-Schmude, Anton Dunsche, Uwe Spetzger, Albert Augustin, Paul Vöhringer","doi":"10.1007/s10354-024-01050-y","DOIUrl":"10.1007/s10354-024-01050-y","url":null,"abstract":"<p><p>We report a case series of severe complications following rhinosinusitis in the winter season 2022/2023 at the Franz-Lust Hospital for children and adolescents. Due to the severity of these complications in children with suspected complicated rhinosinusitis/orbital phlegmona, an immediate interdisciplinary approach is mandatory to prevent long-term sequelae. In addition, during this time period, we observed the unusual occurrrence of a number of invasive streptococcal infections in this age cohort.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"225-230"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}