World journal of radiology最新文献

{"title":"Right-to-left shunt detection in patent foramen ovale: The value of synchronized contrast transcranial Doppler and contrast transthoracic echocardiography.","authors":"Yu-Yin Wang, Lu Xie, Jun-Bang Feng, Yang-Yang Xu, Chuan-Ming Li","doi":"10.4329/wjr.v17.i5.105951","DOIUrl":"10.4329/wjr.v17.i5.105951","url":null,"abstract":"<p><p>Patent foramen ovale (PFO) is a common congenital heart disorder associated with stroke, decompression sickness and migraine. Combining synchronized contrast transcranial Doppler with contrast transthoracic echocardiography has important clinical significance and can improve the accuracy of detecting right-left shunts (RLSs) in patients with PFO. In this letter, regarding an original study presented by Yao <i>et al</i>, we present our insights and discuss how to better help clinicians evaluate changes in PFO-related RLS.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 5","pages":"105951"},"PeriodicalIF":1.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Calciphylaxis following liver transplantation in a patient with end-stage renal disease: A case report.","authors":"Xiang-Ling Wei, You-Wen Zhang, Ming Han, Cheng-Jun Sun, Guan-Zhi Lai, Shui-Guo Tang, Rong-Ji Ye, Hao-Qing Xu, Lin-Wei Wu, Wu-Zheng Xia","doi":"10.4329/wjr.v17.i5.105785","DOIUrl":"10.4329/wjr.v17.i5.105785","url":null,"abstract":"<p><strong>Background: </strong>Calciphylaxis, also called calcific uremic arteriolopathy, is characterized by microvascular calcification and occlusion, which is commonly seen in patients with end-stage renal disease (ESRD). Although several studies have demonstrated an association of calciphylaxis with ESRD, reports linking calciphylaxis to LT (LT) are scarce. This report presents a rare case of calciphylaxis in a patient who underwent LT, leading to microvascular occlusion and hyperbilirubinemia.</p><p><strong>Case summary: </strong>A 34-year-old man presented with a 7-day history of jaundice and severe bilateral leg pain. The patient had undergone LT and was put on hemodialysis for one year due to calcineurin inhibitor-induced ESRD. Physical examination revealed jaundice, leathery skin changes, severe muscle pain in both legs, and penile induration. Laboratory tests identified elevated bilirubin levels, gamma-glutamyltransferase, and alkaline phosphatase, while alanine aminotransferase and aspartate aminotransferase concentrations were within normal limits. Computed tomography (CT) revealed extensive calcifications in the subcutaneous tissue. Three-dimensional CT reconstruction indicated significantly reduced blood flow in the hepatic artery, primarily in the small to medium-sized branches. Contrast-enhanced ultrasonography confirmed hepatic ischemia, with no enhancement seen in hepatic artery branches. Liver biopsy specimen revealed no signs of rejection. The patient decided to receive conservative treatment and succumbed to the illness after six months.</p><p><strong>Conclusion: </strong>This case indicates that calciphylaxis should be suspected in patients who have undergone LT with ESRD presenting with hyperbilirubinemia and skin lesions.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 5","pages":"105785"},"PeriodicalIF":1.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic resonance defecography assessment of obstructed defecation syndrome in patients with chronic constipation in a tertiary care hospital.","authors":"Mohammad Haroon Or-Rashid, Anjuman Sultana, Nabila Khanduker, Tarik Alam Ony, Md Mosharraf Hossain, Junaidur Rahman, Mahmud Zaman Chowdhury, Wasih Uddin Ahmed, Md Nashir Uddin, Mohammad Sohel- Uzzaman","doi":"10.4329/wjr.v17.i5.106102","DOIUrl":"10.4329/wjr.v17.i5.106102","url":null,"abstract":"<p><strong>Background: </strong>Obstructed defecation syndrome (ODS) is a subtype of constipation that is considered one of the major pelvic floor dysfunctions affecting the aging population, particularly women over 50 seeking medical care. The condition is characterized by the urge to defecate but an impaired ability to expel the fecal bolus. ODS is associated with various anorectal abnormalities, which are not always apparent during a standard physical examination, requiring specialized imaging techniques for proper diagnosis.</p><p><strong>Aim: </strong>To study the distribution of causes of ODS in patients with chronic constipation by magnetic resonance defecography (MRD).</p><p><strong>Methods: </strong>This observational study evaluated the causes of ODS in 57 patients with chronic constipation who presented to Bangabandhu Sheikh Mujib Medical University between July 2020 and June 2021. After obtaining institutional review board approval and informed consent, patients underwent history taking, physical exams, and relevant investigations. ODS was diagnosed using Rome III criteria, with colonoscopy ruling out organic causes. Standard MRD was performed in different phases, and images were analyzed by expert radiologists and reported in a standardized format.</p><p><strong>Results: </strong>Pelvic floor descent and anorectal junction descent were the most frequent findings, each present in 94.7% of cases. Rectocele was observed in 78.9% of patients, while vaginal or uterine prolapse was seen in 59.4% of females. Less common abnormalities included paradoxical contraction (7%), and there were no cases of sigmoidocele. Functional measurements showed significant differences in pelvic floor dynamics between rest and defecation, particularly in the H-line, M-line, and descent of pelvic organs (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Pelvic floor descent and anorectal descent were the most common findings in patients suffering from ODS, followed by rectocele. Younger females (< 30 years) were most affected.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 5","pages":"106102"},"PeriodicalIF":1.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tract complicated by protein-losing enteropathy: A case report.","authors":"Shan Jiang, Ling-Jian Wang, Cong-Wei Jia, Wei Zhang, Wei Wang, Hai-Long Li, Xiao-Hong Sun, Xuan Qu, Lin Kang","doi":"10.4329/wjr.v17.i5.107141","DOIUrl":"10.4329/wjr.v17.i5.107141","url":null,"abstract":"<p><strong>Background: </strong>Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tract (iNKLPD) is a rare and recently defined entity, recognized in the 2022 WHO classification of hematolymphoid tumors. iNKLPD typically exhibits a benign or slowly progressive clinical course, with disease localized to the gastrointestinal tract. Here, we present what we believe to be the first reported case of iNKLPD associated with protein-losing enteropathy (PLE), characterized by a poor response to chemotherapy and rapid clinical deterioration, culminating in death within a few months.</p><p><strong>Case summary: </strong>We report the case of a 64-year-old man who presented with bilateral lower-extremity edema and fatigue. Laboratory tests revealed marked hypoalbuminemia, while other liver function parameters remained within normal limits. Renal and cardiac function assessments were unremarkable. Histopathological examination of endoscopic biopsies confirmed a diagnosis of iNKLPD of the gastrointestinal tract. The patient was treated with oral prednisone and cyclosporine, which led to temporary improvement in both symptoms and serum albumin levels. However, disease relapse occurred during corticosteroid tapering, accompanied by worsening hypoalbuminemia and refractory diarrhea. The patient died eight months after diagnosis, likely due to disease progression or severe treatment-related complications.</p><p><strong>Conclusion: </strong>iNKLPD generally exhibits an indolent course; nonetheless, the prognosis may be poor if secondary PLE is involved.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 5","pages":"107141"},"PeriodicalIF":1.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of esophageal hiatus size with reflux esophagitis and type I hiatal hernia in patients with obesity.","authors":"Zhong Qi, Xiao-Chen Shi, Wen-Mao Yan, Ri-Xing Bai","doi":"10.4329/wjr.v17.i5.106333","DOIUrl":"10.4329/wjr.v17.i5.106333","url":null,"abstract":"<p><strong>Background: </strong>Chinese surgeons often rely on intraoperative exploration of the esophageal hiatus to determine the need for concurrent type I hiatal hernia (HH) repair during laparoscopic sleeve gastrectomy. However, no standardized criteria for the esophageal hiatus size or indications for exploration exist in China.</p><p><strong>Aim: </strong>To investigate normal anatomical parameter ranges of the esophageal hiatus in patients with obesity.</p><p><strong>Methods: </strong>A total of 158 patients, aged 20-49 years, was analyzed from January 2020 to June 2024. The patients were classified into the no reflux esophagitis (RE) no HH group (HHG), RE group, and type I HHG. The transverse and sagittal diameters and cross-sectional area of the esophageal hiatus were measured using multiplanar reconstruction of the computed tomography images.</p><p><strong>Results: </strong>Body mass index was positively correlated with area and transverse and sagittal diameters of the esophageal hiatus (<i>r</i> = 0.72, 0.69, and 0.54, respectively; <i>P</i> < 0.01). In the no RE no HHG and RE group, the esophageal hiatus size in the subgroup with obesity was greater than that in the non-obesity subgroup (area: 326.15 ± 78 mm² <i>vs</i> 208.12 ± 64.44 mm², transverse diameters: 15.97 ± 2.06 mm <i>vs</i> 13.37 ± 1.99 mm, sagittal diameters: 15.7 ± 2.08 mm <i>vs</i> 11.73 ± 2.08 mm; <i>P</i> < 0.01). Patients with obesity showed no significant differences in esophageal hiatus size with or without RE or HH.</p><p><strong>Conclusion: </strong>The esophageal hiatus size increased with body mass index and was larger in patients with obesity than in those without obesity.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 5","pages":"106333"},"PeriodicalIF":1.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing artificial intelligence to address immune response heterogeneity in low-dose radiation therapy.","authors":"Jing-Qi Zeng, Yi-Wei Gao, Xiao-Bin Jia","doi":"10.4329/wjr.v17.i5.108011","DOIUrl":"10.4329/wjr.v17.i5.108011","url":null,"abstract":"<p><p>Low-dose radiation therapy has emerged as a promising modality for cancer treatment because of its ability to stimulate antitumor immune responses while minimizing damage to healthy tissues. However, the significant heterogeneity in immune responses among patients complicates its clinical application, hindering outcome prediction and treatment personalization. Artificial intelligence (AI) offers a transformative solution by integrating multidimensional data such as immunomics, radiomics, and clinical features to decode complex immune patterns and predict individual therapeutic outcomes. This editorial explored the potential of AI to address immune response heterogeneity in low-dose radiation therapy and proposed an AI-driven framework for precision immunotherapy. While promising, challenges, including data standardization, model interpretability, and clinical validation, must be overcome to ensure successful integration into oncological practice.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 5","pages":"108011"},"PeriodicalIF":1.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical translation of ultra-high dose rate flash radiotherapy: Opportunities, challenges, and prospects.","authors":"Xiang-Xiang Yang, Hui Luo, Jia-Jun Zhang, Heng Ge, Liang Ge","doi":"10.4329/wjr.v17.i4.105722","DOIUrl":"https://doi.org/10.4329/wjr.v17.i4.105722","url":null,"abstract":"<p><p>Ultra-high dose rate flash radiotherapy (FLASH-RT) has attracted wide attention in the field of radiotherapy in recent years. For FLASH-RT, radiation is delivered at a very high dose rate [usually thousands of times compared with conventional radiotherapy (CONV-RT)] in an extremely short time. This novel irradiation technique shows a protective effect on normal tissues, also known as the flash effect. At the same time, FLASH-RT is comparable to CONV-RT in terms of tumor-killing efficacy. As basic research dedicates to uncover the mechanisms by which FLASH-RT reduces radiation-induced normal tissue damage, clinical trials of FLASH-RT have been gradually conducted worldwide. This article systematically reviews the evidence of the feasibility and safety of FLASH-RT in clinical practice and offers insights into the future translation of this technology in clinic.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 4","pages":"105722"},"PeriodicalIF":1.4,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognosis value of pituitary neuroendocrine tumor volume.","authors":"Jian-She Yang","doi":"10.4329/wjr.v17.i4.106186","DOIUrl":"https://doi.org/10.4329/wjr.v17.i4.106186","url":null,"abstract":"<p><p>This study highlights the significance of considering pituitary neuroendocrine tumor volume when determining the appropriate line of therapy for patients with acromegaly. The findings suggest that, although tumor volume may assist in predicting the need for more aggressive treatment strategies, it is not a reliable indicator of disease persistence following surgical intervention. Further research is warranted to investigate additional factors influencing acromegaly treatment outcomes to enhance patient care.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 4","pages":"106186"},"PeriodicalIF":1.4,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promising four-dimensional flow magnetic resonance imaging technique for vascular flow analysis in children.","authors":"Jian-She Yang","doi":"10.4329/wjr.v17.i4.106185","DOIUrl":"https://doi.org/10.4329/wjr.v17.i4.106185","url":null,"abstract":"<p><p>Leesmidt <i>et al</i> present a comprehensive analysis of abdominal vascular flow in children using four-dimensional (4D) flow magnetic resonance imaging (MRI), aim to establish normal hemodynamic values for the abdominal visceral organs and to assess the feasibility of 4D flow MRI (4D-f-MRI) in this population. The researchers performed 4D-f-MRI on 9 pediatric patients with a history or suspicion of bowel pathology. Flow velocities were measured in the abdominal aorta and superior and inferior mesenteric arteries. The quality of the 4D-f-MRI images was evaluated, and the agreement between the measured flow velocities and those obtained from Duplex ultrasound was established. However, due to the specific limitations of this work, future studies should address the issues of small sample size and the specific age group design.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 4","pages":"106185"},"PeriodicalIF":1.4,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time to resolution of radiologically detected hemothorax in trauma patients: A retrospective observational study.","authors":"Khalid Ahmed, Ammar Al-Hassani, Ayman El-Menyar, Syed Nabir, Mohamed Nadeem Ahmed, Ammar Almadani, Ismail Mahmood, Ahammed Mekkodathil, Ruben Peralta, Sandro Rizoli, Hassan Al-Thani","doi":"10.4329/wjr.v17.i4.105960","DOIUrl":"https://doi.org/10.4329/wjr.v17.i4.105960","url":null,"abstract":"<p><strong>Background: </strong>Traumatic hemothorax is a common complication of chest trauma; however, the timeline for its resolution, even with chest tube thoracostomy, remains unclear.</p><p><strong>Aim: </strong>To determine the time to resolution of the hemothorax to ensure safe discharge based on chest radiography (CXR) findings.</p><p><strong>Methods: </strong>A retrospective observational study was conducted at Hamad General Hospital, Qatar, from June 2014 to October 2019, including all patients with hemothorax diagnosed <i>via</i> computed tomography (CT) following chest trauma. Based on the initial imaging study, the hemothorax was divided into right, left, and bilateral.</p><p><strong>Results: </strong>The study included 422 patients. Of the total, 57.82% (<i>n</i> = 244/422) resolved their hemothorax within three days of admission. Among these, 44 patients required chest tube insertion (CTI) and 200 were cleared without it. Between days 3 and 7, an additional 16.83% (<i>n</i> = 71 /422) of cases were resolved, of which 28 required chest tubes. By days 8 to 14, another 11.37% (<i>n</i> = 48/422) were cleared, with 15 patients requiring chest tubes. After 14 days, 13.98% (<i>n</i> = 59/422) of patients still had hemothorax, 14 of whom required CTI.</p><p><strong>Conclusion: </strong>This study showed that a subset of patients continued to experience retained hemothorax despite early tube thoracostomy. Patients with a larger hemothorax, particularly on the left side, showed prolonged resolution times. Regular imaging such as CXR or CT is recommended for up to 14 days post-intervention. After this period, outpatient follow-up is generally safe, although some patients may still have a persistent hemothorax beyond two weeks.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 4","pages":"105960"},"PeriodicalIF":1.4,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}