World journal of radiology最新文献

{"title":"Artificial intelligence in carotid computed tomography angiography plaque detection: Decade of progress and future perspectives.","authors":"Dong-Yang Wang, Tie Yang, Chong-Tao Zhang, Peng-Chao Zhan, Zhen-Xing Miao, Bing-Lin Li, Hang Yang","doi":"10.4329/wjr.v17.i9.110447","DOIUrl":"10.4329/wjr.v17.i9.110447","url":null,"abstract":"<p><p>The application of artificial intelligence (AI) in carotid atherosclerotic plaque detection <i>via</i> computed tomography angiography (CTA) has significantly advanced over the past decade. This mini-review consolidates recent innovations in deep learning architectures, domain adaptation techniques, and automated plaque characterization methodologies. Hybrid models, such as residual U-Net-Pyramid Scene Parsing Network, exhibit a remarkable precision of 80.49% in plaque segmentation, outperforming radiologists in diagnostic efficiency by reducing analysis time from minutes to mere seconds. Domain-adaptive frameworks, such as Lesion Assessment through Tracklet Evaluation, demonstrate robust performance across heterogeneous imaging datasets, achieving an area under the curve (AUC) greater than 0.88. Furthermore, novel approaches integrating U-Net and Efficient-Net architectures, enhanced by Bayesian optimization, have achieved impressive correlation coefficients (0.89) for plaque quantification. AI-powered CTA also enables high-precision three-dimensional vascular segmentation, with a Dice coefficient of 0.9119, and offers superior cardiovascular risk stratification compared to traditional Agatston scoring, yielding AUC values of 0.816 <i>vs</i> 0.729 at a 15-year follow-up. These breakthroughs address key challenges in plaque motion analysis, with systolic retractive motion biomarkers successfully identifying 80% of vulnerable plaques. Looking ahead, future directions focus on enhancing the interpretability of AI models through explainable AI and leveraging federated learning to mitigate data heterogeneity. This mini-review underscores the transformative potential of AI in carotid plaque assessment, offering substantial implications for stroke prevention and personalized cerebrovascular management strategies.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 9","pages":"110447"},"PeriodicalIF":1.5,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep learning approaches for image-based snoring sound analysis in the diagnosis of obstructive sleep apnea-hypopnea syndrome: A systematic review.","authors":"Li Ding, Jian-Xin Peng, Yu-Jun Song","doi":"10.4329/wjr.v17.i9.109116","DOIUrl":"10.4329/wjr.v17.i9.109116","url":null,"abstract":"<p><strong>Background: </strong>Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a highly prevalent sleep-related respiratory disorder associated with serious health risks. Although polysomnography is the clinical gold standard for diagnosis, it is expensive, inconvenient, and unsuitable for population-level screening due to the need for professional scoring and overnight monitoring.</p><p><strong>Aim: </strong>To address these limitations, this review aims to systematically analyze recent advances in deep learning-based OSAHS detection methods using snoring sounds, particularly focusing on graphical signal representations and network architectures.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted following the PRISMA 2009 guidelines, covering publications from 2010 to 2025. Studies were included based on predefined criteria involving the use of deep learning models on snoring sounds transformed into graphical representations such as spectrograms and scalograms. A total of 14 studies were selected for in-depth analysis.</p><p><strong>Results: </strong>This review summarizes the types of signal modalities, datasets, feature extraction methods, and classification frameworks used in the current literatures. The strengths and limitations of different deep network architectures are evaluated.</p><p><strong>Conclusion: </strong>Challenges such as dataset variability, generalizability, model interpretability, and deployment feasibility are also discussed. Future directions highlight the importance of explainable artificial intelligence and domain-adaptive learning for clinically viable OSAHS diagnostic tools.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 9","pages":"109116"},"PeriodicalIF":1.5,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic resonance tractography of the cervical spine: A rapid diffusion tensor imaging protocol to serve as a clinical evaluation tool.","authors":"Emilio P Supsupin, Alejandro Serrano, Christopher Louviere, Luke Pearson, Mauricio Hernandez, Vashisht Sekar, Aboubakr Amer, Ulas Cikla, Mayur Virarkar, Kazim Z Gumus","doi":"10.4329/wjr.v17.i9.110267","DOIUrl":"10.4329/wjr.v17.i9.110267","url":null,"abstract":"<p><strong>Background: </strong>Spinal cord injury can lead to long-term disability, but current imaging methods are limited in predicting outcomes. Rapid diffusion tensor imaging (DTI) has shown promise, yet its clinical utility remains underexplored.</p><p><strong>Aim: </strong>To evaluate the potential applications of a short DTI sequence, incorporated into a cervical spine magnetic resonance imaging (MRI) protocol, for characterizing a range of symptomatic spinal cord pathologies. We propose that cervical spine tractography can provide essential diagnostic information beyond what is currently available from conventional MRI.</p><p><strong>Methods: </strong>We utilized a quick DTI sequence to create tractography models of the cervical spinal cord in four patients with distinct pathologies of various etiologies: Cord contusion, metastasis, myelopathy, and multiple sclerosis. We used DSI Studio software for post-processing of tractography cases. Fiber tract findings for each pathology case were compared to five control cases from the same scanner by looking for individual differences in white matter tract integrity based on the fractional anisotropy (FA) and mean diffusivity (MD) of the regions of interest from controls. These correlated with clinical presentations and conventional MRI findings.</p><p><strong>Results: </strong>Control cases showed consistent and intact tract patterns with stable FA and MD values. In pathological cases, abnormalities in fiber orientation and tract continuity correlated with clinical symptoms and lesion locations.</p><p><strong>Conclusion: </strong>The tractography models can provide additional information on white matter disruption that was not discernible on standard MRI sequences. However, its clinical use remains limited due to the need for specialized imaging protocols and complex post-processing, restricting its use to mostly academic settings.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 9","pages":"110267"},"PeriodicalIF":1.5,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uterine artery Doppler at 11-14 weeks of gestation in the prediction of preeclampsia: An observational study.","authors":"Arshed Hussain Parry, Irshad Hassan, Basit Rehaman, Shabir Ahmad Bhat, Shylla Mir, Naseer Ahmad Khan, Irshad Mohiuddin Bhat, Shaafiya Ashraf","doi":"10.4329/wjr.v17.i9.112173","DOIUrl":"10.4329/wjr.v17.i9.112173","url":null,"abstract":"<p><strong>Background: </strong>Pre-eclampsia is a significant challenge in obstetric care and adversely affects the feto-maternal outcomes, causing significant perinatal morbidity and mortality. Early detection of women at higher risk of developing pre-eclampsia in the first trimester provides a vital opportunity to initiate timely prophylactic therapies. First-trimester uterine artery Doppler is gaining prominence as a promising tool in early risk stratification.</p><p><strong>Aim: </strong>To assess the role of uterine artery Doppler in screening for pre-eclampsia at 11-14 weeks of gestation.</p><p><strong>Methods: </strong>Pregnant women attending routine antenatal care between 11 weeks and 14 weeks of gestation and undergoing first-trimester nuchal translucency screening were offered enrolment in the study. After calculating gestational age from the last menstrual period or fetal biometry (crown-rump length), Doppler ultrasound of bilateral uterine arteries was performed, and relevant Doppler parameters were recorded. Patients were followed until delivery for development of preeclampsia.</p><p><strong>Results: </strong>Out of a total of 342 participants, 42 women (12.28%) developed preeclampsia, while the remaining 300 women (87.71%) had a normal pregnancy without preeclampsia. The mean uterine artery pulsatility index was significantly elevated in the pre-eclampsia group (1.9455 ± 0.36) compared to the normal group (1.474 ± 0.52) (<i>P</i> < 0.001). Using a pulsatility index threshold of 1.622, the receiver operating characteristic curve analysis demonstrated a sensitivity of 75% (95% confidence internal: 0.66-0.82), specificity of 86% (95% confidence internal: 0.78-0.91), positive predictive value of 84.27%, and negative predictive value of 77.48% with a diagnostic accuracy of 80.5%. The area under the curve was 0.896, indicating good diagnostic performance. Uterine artery notching was observed in 88% of the pre-eclampsia group compared to 16% in the control group, a difference that was statistically significant (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Uterine artery Doppler in the first trimester at 11-14 weeks of gestation showed a good diagnostic value for forecasting the development of pre-eclampsia and holds promise as a valuable tool for early risk stratification.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 9","pages":"112173"},"PeriodicalIF":1.5,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermal field management improves patient-reported outcomes during ablation for papillary thyroid carcinoma: A retrospective cohort study.","authors":"Wen-Jia Cai, Yan Li, Ying Wei, Zhen-Long Zhao, Jie Wu, Shi-Liang Cao, Li-Li Peng, Shu-Qi Li, Ming-An Yu","doi":"10.4329/wjr.v17.i9.111924","DOIUrl":"10.4329/wjr.v17.i9.111924","url":null,"abstract":"<p><strong>Background: </strong>Thermal ablation (TA) has been proved to be effective and safe as minimally invasive treatment method for thyroid nodules. However, patients' experience during the procedures and quality of life varies among operators.</p><p><strong>Aim: </strong>To explore strategy to improve quality of life and subjective experiences during TA for papillary thyroid carcinoma (PTC) based on thermal field management (TFM).</p><p><strong>Methods: </strong>This retrospective propensity-matched cohort study was conducted in a single center. A total of 490 patients with PTC treated with TA from September 2023 to August 2024 were studied and divided into two groups (TFM group and non-TFM group) according to treatment strategies. Propensity score matching (PSM) was used to control for confounding factors. Complications, side effect and complaints of patients were compared between the two groups.</p><p><strong>Results: </strong>A total of 113 patients (41.7 ± 10.6; 31 men, 82 women) were assigned to the TFM group, and 377 patients (mean age, 41.1 ± 10.7 year; 116 men, 261 women) were assigned to the non-TFM group. After PSM, a total of 108 patients were included in the TFM group, and 216 patients were included in the non-TFM group. The median follow-up was 10 months (range from 4-15 months). The incidence of voice change in the TFM group was significantly lower than that in the non-TFM group (0.9% <i>vs</i> 6.5%; <i>P</i> = 0.049). Although there was no statistically significant difference in rate of pain between the two groups, the proportion of complaining of pain in the TFM group was numerically lower than that in the non-TFM group (3.7% <i>vs</i> 9.7%, <i>P</i> = 0.090).</p><p><strong>Conclusion: </strong>TFM, as a novel procedural optimization technique, can effectively improve quality of life and subjective experiences of patients during TA for PTC.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 9","pages":"111924"},"PeriodicalIF":1.5,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complications and expected imaging findings after endoscopic retrograde cholangiopancreatography.","authors":"Mehmet Simsar, Yesim Yekta Yuruk, Olgun Sahin, Hilal Sahin","doi":"10.4329/wjr.v17.i9.110214","DOIUrl":"10.4329/wjr.v17.i9.110214","url":null,"abstract":"<p><p>Endoscopic retrograde cholangiopancreatography (ERCP) is a cornerstone procedure for the diagnosis and management of pancreatic and hepatobiliary diseases. Although its diagnostic role has been increasingly supplanted by noninvasive imaging modalities such as magnetic resonance imaging (MRI) and magnetic resonance cholangiopancreatography, the therapeutic applications of ERCP have continued to expand. ERCP is widely used and has a generally favorable safety profile. However, it is important to recognize expected post-procedural imaging findings and serious complications that can arise. The increasing complexity of therapeutic interventions and the growing volume of procedures have led to a higher incidence of complications that often present with overlapping clinical and laboratory features, underscoring the critical role of imaging in differential diagnosis. This review focused on the typical normal ERCP findings and the imaging characteristics of common complications, including pancreatitis, bleeding, ERCP-related infections, perforations, and stent-related complications. Computed tomography (CT) is particularly valuable in timely recognition, management, and surgical decision-making for these complications. Furthermore, MRI offers a radiation-free alternative for managing complications in selected patients. Therefore, radiological modalities, particularly CT and MRI, are critical tools for the rapid diagnosis, management, and surgical decision-making processes for post-ERCP complications.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 9","pages":"110214"},"PeriodicalIF":1.5,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting hematoma growth in spontaneous intracerebral hemorrhage: A simplified non-contrast computed tomography based five-point grading approach.","authors":"Arshed Hussain Parry, Syeed Aalishan Fatima, Mahrukh Wani, Majid Jehangir, Omar Farooq, Mohmed Imran Wagay, Obaid Ashraf, Aijaz Ahmad Hakeem","doi":"10.4329/wjr.v17.i9.112983","DOIUrl":"10.4329/wjr.v17.i9.112983","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Intracerebral hemorrhage (ICH) comprises 9%-27% of stroke patients. Hematoma expansion (HE) occurs in approximately 20% of patients following ICH, typically within the first 24 hours. HE increases mortality and long-term disability in these patients and is being investigated as a therapeutic target to improve the outcome in these patients by limiting HE. Non-contrast computed tomography (NCCT) has potential in predicting HE, which can identify the individuals at risk.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To evaluate NCCT markers for predicting HE in patients with ICH and to develop a simple, practical grading system for risk stratification.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This prospective observational study evaluated 192 patients with spontaneous ICH who underwent a baseline NCCT within four hours of admission, followed by a follow-up scan after six hours or earlier if there was clinical deterioration. Hematoma volumes and imaging characteristics that predicted HE were evaluated. A simple five-point grading system score was created to predict HE. In this scoring system, five imaging parameters were evaluated, with each parameter assigned a score of either 0 or 1. The parameters included: (1) Baseline hematoma volume ≥ 30 mL &lt;i&gt;vs&lt;/i&gt; &lt; 30 mL; (2) Presence or absence of intraventricular hemorrhage; (3) Presence or absence of the island sign; (4) Presence or absence of the black hole sign; and (5) Presence or absence of the swirl sign.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Of the 192 patients studied, HE was seen in 106 (55.2%). The mean baseline hematoma volume was significantly greater among patients in the HE group (44.1 mL) compared to those in the non-HE group (12.2 mL), with a &lt;i&gt;P&lt;/i&gt;-value &lt; 0.05. Additionally, imaging biomarkers such as the island sign, swirl sign, and black hole sign were observed with significantly higher frequency in the HE group relative to the non-HE cohort (all &lt;i&gt;P&lt;/i&gt;-values &lt; 0.05). The island sign was strongly associated with HE [odds ratio (OR) 13.7; 95% confidence interval (CI): 10.15-16.37; &lt;i&gt;P&lt;/i&gt; &lt; 0.001]. Similarly, the black hole sign (OR 9.4; 95%CI: 7.4-11.62; &lt;i&gt;P&lt;/i&gt; &lt; 0.001) and the swirl sign (OR 5.2; 95%CI: 3.72-6.53; &lt;i&gt;P&lt;/i&gt; &lt; 0.001) emerged as significant predictors of HE. Initial hematoma volume ≥ 30 mL also showed a significant association (OR 1.9; 95%CI: 1.41-2.74; &lt;i&gt;P&lt;/i&gt; = 0.039). A five-point predictive scoring model demonstrated a strong positive association between increasing scores and the probability of HE. Specifically, the likelihood of HE corresponding to scores of 0, 1, 2, 3, 4, and 5 was 7.4%, 37.5%, 75%, 85%, 93.3%, and 100%, respectively.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The five variables demonstrated statistically significant associations with HE. This simple and practical 5-point prediction score can enable identification of patients at elevated risk of HE based on baseline NCCT findings. This can facilitate timely recognition of high-risk individuals who ","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 9","pages":"112983"},"PeriodicalIF":1.5,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of endometrial peristalsis analysis technique in detecting and analyzing endometrial peristalsis features.","authors":"Hui-Ping Zhang, Miao-Ling Chen, Sheng-Lin Xue, Jie Zou, Jing-Jing Wu, Yu-Qing Zhou","doi":"10.4329/wjr.v17.i9.111215","DOIUrl":"10.4329/wjr.v17.i9.111215","url":null,"abstract":"<p><strong>Background: </strong>Endometrial peristalsis (EmP) has been considered as a new indicator for evaluating endometrial receptivity and is associated with embryo implantation rate and successful pregnancy rate. However, EmP remains understudied, inconsistently measured, and poorly understood. New methods are needed urgently for better clinical practice.</p><p><strong>Aim: </strong>To explore the value of EmP analysis (EmPA) technique in detecting and analyzing EmP features automatically and quantitatively.</p><p><strong>Methods: </strong>One hundred and forty-five patients without abnormal findings on conventional transvaginal ultrasound were included in this study. A mid sagittal plane of uterus was recorded for 2 minutes in each patient and EmP features were analyzed using EmPA technique. EmP features in 50 patients were also analyzed by naked eyes analysis and the results of two methods were compared.</p><p><strong>Results: </strong>EmPA was unsuccessful in 9 patients (9/145, 6.21%) due to the interference of respiratory or intestinal movement and was successful in 136 patients (136/145, 93.79%), of whom 21 patients showed no EmP and 115 patients underwent EmPA and obtained quantitative results. The results of EmPA technique and naked eyes analysis about EmP intensity and transfer time had no significant consistence. Menstrual cycle, uterine position and history of induced abortion affected the quantitative results of EmPA.</p><p><strong>Conclusion: </strong>EmPA technique provides noninvasive, quantitative and accurate detection and analysis of EmP in normal population and can evaluate EmP changes associated with menstrual cycle, uterine position and history of induced abortion.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 9","pages":"111215"},"PeriodicalIF":1.5,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A compendium of male breast imaging: The road less traveled.","authors":"Veenu Singla, Harsimran Bhatia, Dollphy Garg, Amanjit Bal, Aravind Sekar","doi":"10.4329/wjr.v17.i9.110906","DOIUrl":"10.4329/wjr.v17.i9.110906","url":null,"abstract":"<p><p>Male breast disorders, though less prevalent, present unique diagnostic challenges that differ significantly from their female counterparts. While benign entities such as gynecomastia are predominant, the risk of underlying malignancy, often diagnosed at an advanced stage, highlights the need for a systematic, image-guided assessment. Ultrasound and mammography are the first-line complementary tools, with magnetic resonance imaging reserved for problem-solving. This review outlines the anatomical, pathological, and radiological nuances of the male breast, describing crucial red flag signs, sonographic pitfalls, and mammographic mimics that aid in distinguishing benign entities from sinister pathologies such as invasive ductal carcinoma. Given the increasing visibility of transgender individuals, this review also addresses imaging considerations and screening recommendations tailored to this population. By integrating clinical insights with radiologic imaging, this review offers a comprehensive approach to both common and not-so-common male breast lesions, with an emphasis on an algorithmic stepwise diagnostic approach.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 9","pages":"110906"},"PeriodicalIF":1.5,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive linkage between molecular biology and imaging radiomics for thyroid nodules.","authors":"Zhen-Xing He, Xiao-Ping Zhang, Jian-She Yang","doi":"10.4329/wjr.v17.i9.111005","DOIUrl":"10.4329/wjr.v17.i9.111005","url":null,"abstract":"<p><p>Thyroid nodules are common, with a prevalence of approximately 70% on thyroid ultrasonography; approximately 5% of these nodules are malignant. Distinguishing malignant and benign thyroid nodules is critical for clinical management. Clinicians can judiciously select patients for fine-needle aspiration, understand the cytology results and subsequent follow-up, and determine surveillance strategies for non-operated nodules. The challenge in selecting thyroid nodules for fine-needle aspiration is to avoid the diagnosis of small, clinically insignificant cancers without missing more severe diseases. The molecular characteristics of thyroid nodules are critical for their diagnosis and treatment. However, identifying these characteristics is costly and challenging because of unexpected technical difficulties. An imaging association model based on molecular features will bridge the essential link between molecular characteristics and the computed tomography radiomics, then improve diagnostic efficiency, reducing invasive examinations.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"17 9","pages":"111005"},"PeriodicalIF":1.5,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}