Yu-Ting Lai, Yi Chen, Tai-Shi Fang, Zhi-Yan Li, Ning-Bo Zhao
{"title":"Prediction of hepatic artery occlusion after liver transplantation by ultrasound characteristics and clinical risk factors.","authors":"Yu-Ting Lai, Yi Chen, Tai-Shi Fang, Zhi-Yan Li, Ning-Bo Zhao","doi":"10.4329/wjr.v16.i6.196","DOIUrl":"10.4329/wjr.v16.i6.196","url":null,"abstract":"<p><strong>Background: </strong>Hepatic artery occlusion (HAO) after liver transplantation (LT) is a devastating complication, resulting in early graft loss and reduced overall survival. Ultrasound is an established assessment method for HAO in patients following LT, especially those with complex hepatic artery reconstruction.</p><p><strong>Aim: </strong>To investigate the ultrasound characteristics and analyze the risk factors associated with HAO in patients after LT.</p><p><strong>Methods: </strong>We retrospectively analyzed the ultrasound characteristics and the clinic risk factors associated with HAO in 400 adult LT patients who were enrolled and treated at the Third People's Hospital of Shenzhen between November 2016 and July 2022. Fourteen patients diagnosed with acute HAO (A-HAO) by surgery and fifteen diagnosed with chronic HAO (C-HAO) were included. A control group of 33 patients without HAO complications during the same period were randomly selected using a random number table. All patients underwent an ultrasonography examination. Parameters including resistance index (RI), peak systolic velocity (PSV), and portal vein velocity (PVV) were compared across the groups. Additionally, basic clinical data were collected for all patients, including gender, age, primary diagnosis, D-dimer concentration, total operation time, cold ischemia time, hot ischemia time, intraoperative blood loss and transfusion, intraoperative urine volume, infusion, model for end-stage liver disease (MELD) score, and whether complex hepatic artery reconstructions were performed. Furthermore, risk factors influencing HAO formation after LT were analyzed.</p><p><strong>Results: </strong>Compared to the non-HAO group, PVV and RI were higher in the A-HAO group, while PSV was lower. Conversely, both PSV and RI were lower in the C-HAO group compared to the non-HAO group. The proportion of patients undergoing complex hepatic artery reconstructions and the gamma-glutamyltransferase (GGT) level before occlusion were significantly higher in the A-HAO group compared to the non-HAO group. However, there were no distinct differences between the two groups in D-dimer, MELD score, pre-occlusion alanine transaminase and aspartate transaminase levels, or intraoperative conditions.</p><p><strong>Conclusion: </strong>Ultrasound features of the hepatic artery before occlusion are significantly associated with postoperative HAO development. Additionally, complex hepatic artery reconstructions, defined as revascularization of the graft requiring additional anastomosis between donor hepatic arteries, constitute a risk factor for A-HAO. Besides, abnormal pre-occlusion GGT elevation is an important biochemical indicator. Therefore, ultrasound examination serves as an important tool for screening HAO, especially in patients with the identified risk factors.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"16 6","pages":"196-202"},"PeriodicalIF":1.4,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141564537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interdepartmental miscommunication regarding radiology: Addressing chronic challenges and exploring solutions.","authors":"Nikolaos-Achilleas Arkoudis, Emmanouil Karofylakis, Ornella Moschovaki-Zeiger, Spyridon Prountzos, Evgenia Efthymiou, George Samonis, Christos Koutserimpas","doi":"10.4329/wjr.v16.i5.109","DOIUrl":"10.4329/wjr.v16.i5.109","url":null,"abstract":"<p><p>Effective communication and collaboration among healthcare professionals are crucial for delivering high-quality patient care. Interdepartmental miscommunication poses a significant challenge to healthcare systems, potentially undermining the quality of healthcare services provided. In the same manner, communication barriers between referring physicians and radiologists can specifically affect radiology services and patient outcomes. This article attempts to put the spotlight on the ever-present chronic challenges of this issue and prompt readers to recognize the relevant potential pitfalls in their daily clinical practice. Practical solutions are explored and proposed, which should be tailored to the specific needs and issues that each individual institution may face.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"16 5","pages":"109-114"},"PeriodicalIF":2.5,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11151895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Maria Cacioppa, Chiara Floridi, Alessandra Bruno, Nicolò Rossini, Tommaso Valeri, Alessandra Borgheresi, Riccardo Inchingolo, Francesco Cortese, Giacomo Novelli, Alessandro Felicioli, Mario Torresi, Pietro Boscarato, Letizia Ottaviani, Andrea Giovagnoni
{"title":"Extravasated contrast volumetric assessment on computed tomography angiography in gastrointestinal bleeding: A useful predictor of positive angiographic findings.","authors":"Laura Maria Cacioppa, Chiara Floridi, Alessandra Bruno, Nicolò Rossini, Tommaso Valeri, Alessandra Borgheresi, Riccardo Inchingolo, Francesco Cortese, Giacomo Novelli, Alessandro Felicioli, Mario Torresi, Pietro Boscarato, Letizia Ottaviani, Andrea Giovagnoni","doi":"10.4329/wjr.v16.i5.115","DOIUrl":"10.4329/wjr.v16.i5.115","url":null,"abstract":"<p><strong>Background: </strong>Gastrointestinal bleeding (GIB) is a severe and potentially life-threatening condition, especially in cases of delayed treatment. Computed tomography angiography (CTA) plays a pivotal role in the early identification of upper and lower GIB and in the prompt treatment of the haemorrhage.</p><p><strong>Aim: </strong>To determine whether a volumetric estimation of the extravasated contrast at CTA in GIB may be a predictor of subsequent positive angiographic findings.</p><p><strong>Methods: </strong>In this retrospective single-centre study, 35 patients (22 men; median age 69 years; range 16-92 years) admitted to our institution for active GIB detected at CTA and further submitted to catheter angiography between January 2018 and February 2022 were enrolled. Twenty-three (65.7%) patients underwent endoscopy before CTA. Bleeding volumetry was evaluated in both arterial and venous phases <i>via</i> a semi-automated dedicated software. Bleeding rate was obtained from volume change between the two phases and standardised for unit time. Patients were divided into two groups, according to the angiographic signs and their concordance with CTA.</p><p><strong>Results: </strong>Upper bleeding accounted for 42.9% and lower GIB for 57.1%. Mean haemoglobin value at the admission was 7.7 g/dL. A concordance between positive CTA and direct angiographic bleeding signs was found in 19 (54.3%) cases. Despite no significant differences in terms of bleeding volume in the arterial phase (0.55 mL <i>vs</i> 0.33 mL, <i>P</i> = 0.35), a statistically significant volume increase in the venous phase was identified in the group of patients with positive angiography (2.06 mL <i>vs</i> 0.9 mL, <i>P</i> = 0.02). In the latter patient group, a significant increase in bleeding rate was also detected (2.18 mL/min <i>vs</i> 0.19 mL/min, <i>P</i> = 0.02).</p><p><strong>Conclusion: </strong>In GIB of any origin, extravasated contrast volumetric analysis at CTA could be a predictor of positive angiography and may help in avoiding further unnecessary procedures.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"16 5","pages":"115-127"},"PeriodicalIF":2.5,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11151896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of the potential interactions between favipiravir and radiocontrast agents.","authors":"Sonay Aydin, Ozlem Celik Aydin, Mesut Furkan Yazar, Huseyin Aydemir, Mecit Kantarci, Sureyya Barun","doi":"10.4329/wjr.v16.i5.128","DOIUrl":"10.4329/wjr.v16.i5.128","url":null,"abstract":"<p><strong>Background: </strong>In cases of coronavirus disease 2019 (COVID-19), favipiravir is commonly included to the therapy regimen. Drug interactions between favipiravir and other COVID-19 therapy drugs are frequently researched. However, no research on possible drug interactions between Favipiravir and radiocontrast agents, which have become almost crucial in diagnostic processes while not being part of the treatment, has been found.</p><p><strong>Aim: </strong>To determine potential medication interactions between Favipiravir and radiocontrast agents.</p><p><strong>Methods: </strong>The study comprised patients who were taking Favipiravir for COVID-19 therapy and underwent a contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) test while taking the medicine. The computerized patient files of the cases included in the study, as well as the pharmacovigilance forms in the designated hospital, were evaluated for this purpose.</p><p><strong>Results: </strong>The study included the evaluation of data from 1046 patients. The study sample's mean age was 47.23 ± 9.48 years. The mean age of cases with drug interactions was statistically significant greater than that of cases with no drug interactions (<i>P</i> = 0.003). When evaluated with logistic regression analysis, a 1-year raises in age increases the risk of developing drug interactions by 1.63 times (<i>P</i> = 0.023). There was no statistically significant difference in the occurrence of medication interactions between the sexes (<i>P</i> = 0.090). Possible medication interactions were discovered in 42 cases (4%).</p><p><strong>Conclusion: </strong>The findings of this study revealed that the most notable findings as a result of the combined use of contrast agents and favipiravir were increased creatinine and transaminase values, as well as an increase in the frequency of nausea and vomiting. The majority of drug interactions discovered were modest enough that they were not reflected in the clinic. Drug interactions become more common as people get older.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"16 5","pages":"128-135"},"PeriodicalIF":2.5,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11151898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is it a normal phenomenon for pediatric patients to have brain leptomeningeal contrast enhancement on 3-tesla magnetic resonance imaging?","authors":"Min Ai, Hang-Hang Zhang, Yi Guo, Jun-Bang Feng","doi":"10.4329/wjr.v16.i5.136","DOIUrl":"10.4329/wjr.v16.i5.136","url":null,"abstract":"<p><p>Determining whether sevoflurane sedation in children leads to \"pseudo\" prominent leptomeningeal contrast enhancement (pLMCE) on 3 Tesla magnetic resonance imaging will help reduce overdiagnosis by radiologists and clarify the pathophysiological changes of pLMCE.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"16 5","pages":"136-138"},"PeriodicalIF":2.5,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11151897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chronic pancreatitis: Pain and computed tomography/magnetic resonance imaging findings.","authors":"Yue Feng, Ling-Ji Song, Bo Xiao","doi":"10.4329/wjr.v16.i3.40","DOIUrl":"https://doi.org/10.4329/wjr.v16.i3.40","url":null,"abstract":"<p><p>Chronic pancreatitis (CP) is a fibroinflammatory disease characterized by irreversible destruction of pancreatic tissue. With the development of the disease, it may lead to exocrine and/or endocrine insufficiency. CP is one of the common diseases that cause abdominal pain, which will not get permanent spontaneous relief as the disease evolves. The American College of Gastroenterology clinical guidelines recommend computed tomography or magnetic resonance imaging as the first-line examination for the diagnosis of CP. CP common imaging findings include pancreatic atrophy, irregular dilatation of the pancreatic duct, calcification of pancreatic parenchyma, pancreatic duct stones, <i>etc.</i> In clinical practice, whether any correlations between CP-induced abdominal pain patterns (no pain/constant/intermittent pain) and corresponding imaging findings present are not well known. Therefore, this review aims to comprehensively sort out and analyze the relevant information by collecting lots of literature on this field, so as to construct a cross-bridge between the clinical manifestations and imaging manifestations of CP patients. Also, it provides an imaging basis and foundation for the classification and diagnosis of abdominal pain types in clinical CP patients.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"16 3","pages":"40-48"},"PeriodicalIF":2.5,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Binit Katuwal, Amy Thorsen, Kunal Kochar, Ryba Bhullar, Ray King, Ernesto Raul Drelichman, Vijay K Mittal, Jasneet Singh Bhullar
{"title":"Outcomes and efficacy of magnetic resonance imaging-compatible sacral nerve stimulator for management of fecal incontinence: A multi-institutional study.","authors":"Binit Katuwal, Amy Thorsen, Kunal Kochar, Ryba Bhullar, Ray King, Ernesto Raul Drelichman, Vijay K Mittal, Jasneet Singh Bhullar","doi":"10.4329/wjr.v16.i2.32","DOIUrl":"10.4329/wjr.v16.i2.32","url":null,"abstract":"<p><strong>Background: </strong>Fecal incontinence (FI) is an involuntary passage of fecal matter which can have a significant impact on a patient's quality of life. Many modalities of treatment exist for FI. Sacral nerve stimulation is a well-established treatment for FI. Given the increased need of magnetic resonance imaging (MRI) for diagnostics, the InterStim which was previously used in sacral nerve stimulation was limited by MRI incompatibility. Medtronic MRI-compatible InterStim was approved by the United States Food and Drug Administration in August 2020 and has been widely used.</p><p><strong>Aim: </strong>To evaluate the efficacy, outcomes and complications of the MRI-compatible InterStim.</p><p><strong>Methods: </strong>Data of patients who underwent MRI-compatible Medtronic InterStim placement at UPMC Williamsport, University of Minnesota, Advocate Lutheran General Hospital, and University of Wisconsin-Madison was pooled and analyzed. Patient demographics, clinical features, surgical techniques, complications, and outcomes were analyzed. Strengthening the Reporting of Observational studies in Epidemiology(STROBE) cross-sectional reporting guidelines were used.</p><p><strong>Results: </strong>Seventy-three patients had the InterStim implanted. The mean age was 63.29 ± 12.2 years. Fifty-seven (78.1%) patients were females and forty-two (57.5%) patients had diabetes. In addition to incontinence, overlapping symptoms included diarrhea (23.3%), fecal urgency (58.9%), and urinary incontinence (28.8%). Fifteen (20.5%) patients underwent Peripheral Nerve Evaluation before proceeding to definite implant placement. Thirty-two (43.8%) patients underwent rechargeable InterStim placement. Three (4.1%) patients needed removal of the implant. Migration of the external lead connection was observed in 7 (9.6%) patients after the stage I procedure. The explanation for one patient was due to infection. Seven (9.6%) patients had other complications like nerve pain, hematoma, infection, lead fracture, and bleeding. The mean follow-up was 6.62 ± 3.5 mo. Sixty-eight (93.2%) patients reported significant improvement of symptoms on follow-up evaluation.</p><p><strong>Conclusion: </strong>This study shows promising results with significant symptom improvement, good efficacy and good patient outcomes with low complication rates while using MRI compatible InterStim for FI. Further long-term follow-up and future studies with a larger patient population is recommended.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"16 2","pages":"32-39"},"PeriodicalIF":2.5,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10915907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140060608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew Grudza, Brandon Salinel, Sarah Zeien, Matthew Murphy, Jake Adkins, Corey T Jensen, Curtis Bay, Vikram Kodibagkar, Phillip Koo, Tomislav Dragovich, Michael A Choti, Madappa Kundranda, Tanveer Syeda-Mahmood, Hong-Zhi Wang, John Chang
{"title":"Methods for improving colorectal cancer annotation efficiency for artificial intelligence-observer training.","authors":"Matthew Grudza, Brandon Salinel, Sarah Zeien, Matthew Murphy, Jake Adkins, Corey T Jensen, Curtis Bay, Vikram Kodibagkar, Phillip Koo, Tomislav Dragovich, Michael A Choti, Madappa Kundranda, Tanveer Syeda-Mahmood, Hong-Zhi Wang, John Chang","doi":"10.4329/wjr.v15.i12.359","DOIUrl":"10.4329/wjr.v15.i12.359","url":null,"abstract":"<p><strong>Background: </strong>Missing occult cancer lesions accounts for the most diagnostic errors in retrospective radiology reviews as early cancer can be small or subtle, making the lesions difficult to detect. Second-observer is the most effective technique for reducing these events and can be economically implemented with the advent of artificial intelligence (AI).</p><p><strong>Aim: </strong>To achieve appropriate AI model training, a large annotated dataset is necessary to train the AI models. Our goal in this research is to compare two methods for decreasing the annotation time to establish ground truth: Skip-slice annotation and AI-initiated annotation.</p><p><strong>Methods: </strong>We developed a 2D U-Net as an AI second observer for detecting colorectal cancer (CRC) and an ensemble of 5 differently initiated 2D U-Net for ensemble technique. Each model was trained with 51 cases of annotated CRC computed tomography of the abdomen and pelvis, tested with 7 cases, and validated with 20 cases from The Cancer Imaging Archive cases. The sensitivity, false positives per case, and estimated Dice coefficient were obtained for each method of training. We compared the two methods of annotations and the time reduction associated with the technique. The time differences were tested using Friedman's two-way analysis of variance.</p><p><strong>Results: </strong>Sparse annotation significantly reduces the time for annotation particularly skipping 2 slices at a time (<i>P</i> < 0.001). Reduction of up to 2/3 of the annotation does not reduce AI model sensitivity or false positives per case. Although initializing human annotation with AI reduces the annotation time, the reduction is minimal, even when using an ensemble AI to decrease false positives.</p><p><strong>Conclusion: </strong>Our data support the sparse annotation technique as an efficient technique for reducing the time needed to establish the ground truth.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"15 12","pages":"359-369"},"PeriodicalIF":2.5,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10762523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139098814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deep learning-based magnetic resonance imaging reconstruction for improving the image quality of reduced-field-of-view diffusion-weighted imaging of the pancreas.","authors":"Yukihisa Takayama, Keisuke Sato, Shinji Tanaka, Ryo Murayama, Nahoko Goto, Kengo Yoshimitsu","doi":"10.4329/wjr.v15.i12.338","DOIUrl":"10.4329/wjr.v15.i12.338","url":null,"abstract":"<p><strong>Background: </strong>It has been reported that deep learning-based reconstruction (DLR) can reduce image noise and artifacts, thereby improving the signal-to-noise ratio and image sharpness. However, no previous studies have evaluated the efficacy of DLR in improving image quality in reduced-field-of-view (reduced-FOV) diffusion-weighted imaging (DWI) [field-of-view optimized and constrained undistorted single-shot (FOCUS)] of the pancreas. We hypothesized that a combination of these techniques would improve DWI image quality without prolonging the scan time but would influence the apparent diffusion coefficient calculation.</p><p><strong>Aim: </strong>To evaluate the efficacy of DLR for image quality improvement of FOCUS of the pancreas.</p><p><strong>Methods: </strong>This was a retrospective study evaluated 37 patients with pancreatic cystic lesions who underwent magnetic resonance imaging between August 2021 and October 2021. We evaluated three types of FOCUS examinations: FOCUS with DLR (FOCUS-DLR+), FOCUS without DLR (FOCUS-DLR-), and conventional FOCUS (FOCUS-conv). The three types of FOCUS and their apparent diffusion coefficient (ADC) maps were compared qualitatively and quantitatively.</p><p><strong>Results: </strong>FOCUS-DLR+ (3.62, average score of two radiologists) showed significantly better qualitative scores for image noise than FOCUS-DLR- (2.62) and FOCUS-conv (2.88) (<i>P</i> < 0.05). Furthermore, FOCUS-DLR+ showed the highest contrast ratio (CR) between the pancreatic parenchyma and adjacent fat tissue for b-values of 0 and 600 s/mm<sup>2</sup> (0.72 ± 0.08 and 0.68 ± 0.08) and FOCUS-DLR- showed the highest CR between cystic lesions and the pancreatic parenchyma for the b-values of 0 and 600 s/mm<sup>2</sup> (0.62 ± 0.21 and 0.62 ± 0.21) (<i>P</i> < 0.05), respectively. FOCUS-DLR+ provided significantly higher ADCs of the pancreas and lesion (1.44 ± 0.24 and 3.00 ± 0.66) compared to FOCUS-DLR- (1.39 ± 0.22 and 2.86 ± 0.61) and significantly lower ADCs compared to FOCUS-conv (1.84 ± 0.45 and 3.32 ± 0.70) (<i>P</i> < 0.05), respectively.</p><p><strong>Conclusion: </strong>This study evaluated the efficacy of DLR for image quality improvement in reduced-FOV DWI of the pancreas. DLR can significantly denoise images without prolonging the scan time or decreasing the spatial resolution. The denoising level of DWI can be controlled to make the images appear more natural to the human eye. However, this study revealed that DLR did not ameliorate pancreatic distortion. Additionally, physicians should pay attention to the interpretation of ADCs after DLR application because ADCs are significantly changed by DLR.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"15 12","pages":"338-349"},"PeriodicalIF":2.5,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10762521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139098812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors associated with gastrointestinal stromal tumor rupture and pathological risk: A single-center retrospective study.","authors":"Jia-Zheng Liu, Zhong-Wen Jia, Ling-Ling Sun","doi":"10.4329/wjr.v15.i12.350","DOIUrl":"10.4329/wjr.v15.i12.350","url":null,"abstract":"<p><strong>Background: </strong>Gastrointestinal stromal tumor (GIST) is a rare gastrointestinal mesenchymal tumor with potential malignancy. Once the tumor ruptures, regardless of tumor size and mitotic number, it can be identified into a high-risk group. It is of great significance for the diagnosis, treatment, and prognosis of GIST if non-invasive examination can be performed before surgery to accurately assess the risk of tumor.</p><p><strong>Aim: </strong>To identify the factors associated with GIST rupture and pathological risk.</p><p><strong>Methods: </strong>A cohort of 50 patients with GISTs, as confirmed by postoperative pathology, was selected from our hospital. Clinicopathological and computed tomography data of the patients were collected. Logistic regression analysis was used to evaluate factors associated with GIST rupture and pathological risk grade.</p><p><strong>Results: </strong>Pathological risk grade, tumor diameter, tumor morphology, internal necrosis, gas-liquid interface, and Ki-67 index exhibited significant associations with GIST rupture (<i>P</i> < 0.05). Gender, tumor diameter, tumor rupture, and Ki-67 index were found to be correlated with pathological risk grade of GIST (<i>P</i> < 0.05). Multifactorial logistic regression analysis revealed that male gender and tumor diameter ≥ 10 cm were independent predictors of a high pathological risk grade of GIST [odds ratio (OR) = 11.12, 95% confidence interval (95%CI): 1.81-68.52, <i>P</i> = 0.01; OR = 22.96, 95%CI: 2.19-240.93, <i>P</i> = 0.01]. Tumor diameter ≥ 10 cm, irregular shape, internal necrosis, gas-liquid interface, and Ki-67 index ≥ 10 were identified as independent predictors of a high risk of GIST rupture (OR = 9.67, 95%CI: 2.15-43.56, <i>P</i> = 0.01; OR = 35.44, 95%CI: 4.01-313.38, <i>P</i> < 0.01; OR = 18.75, 95%CI: 3.40-103.34, <i>P</i> < 0.01; OR = 27.00, 95%CI: 3.10-235.02, <i>P</i> < 0.01; OR = 4.43, 95%CI: 1.10-17.92, <i>P</i> = 0.04).</p><p><strong>Conclusion: </strong>Tumor diameter, tumor morphology, internal necrosis, gas-liquid, and Ki-67 index are associated with GIST rupture, while gender and tumor diameter are linked to the pathological risk of GIST. These findings contribute to our understanding of GIST and may inform non-invasive examination strategies and risk assessment for this condition.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"15 12","pages":"350-358"},"PeriodicalIF":2.5,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10762522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139098813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}