World journal of microbiology & biotechnology最新文献

{"title":"An in-depth review on antimicrobial efficacy of melittin in vivo.","authors":"Hamed Memariani, Mojtaba Memariani, Mohammadali Mazloumi","doi":"10.1007/s11274-026-05308-y","DOIUrl":"10.1007/s11274-026-05308-y","url":null,"abstract":"<p><p>The past couple of decades have witnessed growing interest in the therapeutic potential of melittin, the main peptide constituent of honeybee venom. Given the rapid growth of in vivo studies investigating the antimicrobial efficacy of melittin and the absence of a thorough review devoted to this subject, a critical evaluation of the literature has become both necessary and opportune. This review commences with a brief overview of the structural characteristics and biological properties of melittin, followed by an evaluation of the in vivo evidence supporting its antibacterial, antifungal, antiprotozoal, and antiviral activities. The limitations of the available studies are also considered, and future research priorities are identified to guide the continued development and clinical translation of this multifunctional peptide. Evidence indicates that melittin can reduce microbial burdens in selected experimental infection models and modulate inflammatory responses. However, the magnitude and nature of these effects vary according to the pathogen, infection model, host context, administration route, dose, and formulation. The continued development of melittin as a therapeutic candidate will require a multidisciplinary strategy. Further efforts should be made to develop biocompatible delivery platforms, including inorganic nanomaterials, polymeric carriers, lipid-based systems, and hydrogels. Additionally, combination therapies with conventional antimicrobial agents or other antimicrobial peptides should be explored. Overall, melittin represents a promising anti-infective candidate, although further studies are required to define its therapeutic window, pharmacokinetic and biodistribution profiles, long-term safety, immunogenicity, and appropriate delivery strategies.</p>","PeriodicalId":23703,"journal":{"name":"World journal of microbiology & biotechnology","volume":"42 10","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Valorization of Citrus limetta peel powder for probiotic encapsulation: enhanced gastrointestinal and storage stability of Lactiplantibacillus plantarum RAD1 isolated from fermented radish (Raphanus sativus L.).","authors":"Divya Limbu, Manab Deb Adhikari","doi":"10.1007/s11274-026-05309-x","DOIUrl":"10.1007/s11274-026-05309-x","url":null,"abstract":"<p><p>Probiotics offer significant health benefits when consumed in adequate amounts; however, their viability is often compromised during processing, storage, and transit through the gastrointestinal tract, which limits their effectiveness in functional food applications. In the present study, seventeen indigenous LAB strains were isolated from fermented radish, among which six strains showed potential probiotic characteristics. The strain revealed to have the most desirable probiotic attributes was identified as Lactiplantibacillus plantarum, as confirmed by 16 S rRNA gene sequencing. Further, we assessed the viability and stability of L. plantarum RAD1 under simulated gastrointestinal conditions and in pasteurized mosambi juice after encapsulation with alginate and Citrus limetta peel powder (CLPP). The alginate beads (Alg) and CLPP-coated Alg beads (Alg@CLPP) were characterized by SEM and FTIR to evaluate the size, morphology, and interaction between the bacteria and wall materials. The Alg@CLPP beads showed a satisfactory encapsulation efficiency of around 96.07% and significantly improved cell viability in simulated gastric fluids compared to free cells. The viability of free and encapsulated L. plantarum RAD1 was also studied in pasteurized mosambi juice, and physicochemical characterization of the juice was performed in terms of pH and titratable acidity over 28 days of storage at 4℃. The CLPP-coated beads revealed a protective effect on RAD1, enhancing its survival in fruit juice under storage conditions. In conclusion, this study presents a formulation for encapsulating probiotics as dietary supplements, aiming to promote human health benefits while also proposing an innovative approach to valorizing agricultural by-products, thereby addressing food waste while contributing to the development of sustainable, health-oriented dietary supplements.</p>","PeriodicalId":23703,"journal":{"name":"World journal of microbiology & biotechnology","volume":"42 10","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring archaeal resources for biomass-derived pentose utilization: pathways, extremozymes, and bioprocessing applications.","authors":"Zixuan Wan, Meng Liao, Longqing Wang, Hongtao Bi, Chunjie Gong","doi":"10.1007/s11274-026-05289-y","DOIUrl":"10.1007/s11274-026-05289-y","url":null,"abstract":"<p><p>Currently, energy scarcity and the demand for sustainable carbon resources have increased interest in the conversion of biomass-derived sugars. Compared with hexoses, plant-derived pentoses, especially xylose and arabinose, are still inefficiently utilized by many microorganisms. This limitation reduces the conversion efficiency of biomass resources and highlights the need to explore new microbial pathways for pentose transformation. With the development of genomic sequencing, many previously unknown archaeal lineages have been identified from microbial dark matter, providing new opportunities to discover unconventional metabolic pathways and enzymes. Recent advances in biotechnology have further highlighted the potential of archaea in the utilization of plant pentoses. In this review, we summarize current progress in plant pentose utilization by archaea, focusing on the metabolism of xylose and arabinose. We also discuss the major metabolic pathways, key enzymes, and regulatory features involved in archaeal pentose conversion. Finally, the potential applications of archaeal pentose metabolism in industrial biotechnology, biomass conversion, and bioproduct synthesis are discussed.</p>","PeriodicalId":23703,"journal":{"name":"World journal of microbiology & biotechnology","volume":"42 10","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isoelectric point stabilization and protein mass compression are associated with antimicrobial resistance in the genus Acinetobacter.","authors":"Ujwal Dahal, Archana Gautam, Pinky Arora, Mukti Ram Aryal, Mahesh Kc","doi":"10.1007/s11274-026-05295-0","DOIUrl":"10.1007/s11274-026-05295-0","url":null,"abstract":"<p><strong>Introduction: </strong>The genus Acinetobacter is widely regarded as a major reservoir of antimicrobial resistance (AMR); however, the evolutionary distribution of resistance across the genus remains unclear. This study aimed to investigate phylogenomic structure and associated proteomic features underlying AMR distribution.</p><p><strong>Methods: </strong>A total 67 genomes including 65 representative Acinetobacter species, one additional Acinetobacter baumannii ATCC 19606 reference genome and Alkanindiges hydrocarboniclasticus as the outgroup were analyzed using a 174-gene core genome phylogeny. Resistome profiling was performed using homology-based screening, and proteome-wide properties, including isoelectric point (pI), molecular weight, and protein count, were statistically compared between antibiotic resistance gene (ARG) positive and ARG negative groups based on Resfinder Screening.</p><p><strong>Results: </strong>Phylogenetic analysis revealed a clear partitioning into ARG positive and ARG negative clades with 28 lineages lacking detectable AMR determinants. A Chi-square test confirmed a significant association between evolutionary clades and resistome distribution (X2 = 29.69, p = 0.0052). While global pI values remained conserved, ARG positive lineages showed significantly reduced pI variance (p = 0.0054). Additionally, ARG positive lineages exhibited expanded proteomes (p < 0.0001) coupled with reduced average molecular weight (p = 0.0056), indicating a shift toward a more compact proteome architecture.</p><p><strong>Conclusion: </strong>These findings suggest that AMR evolution in Acinetobacter is associated with both genomic partitioning and distinct proteomic patterns. The presence of ARG-negative lineages and coordinated differences in proteome size, average molecular weight, and pI variance highlight the potential role of biophysical properties in shaping AMR-associated genomic variation, while the conserved global pI indicates that these differences do not reflect a shift in overall proteome pI. These findings provide a framework for further investigating biophysical features associated with emerging ARG-positive lineages.</p>","PeriodicalId":23703,"journal":{"name":"World journal of microbiology & biotechnology","volume":"42 10","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional divergence of bacterial communities in root zones of Suaeda salsa in an aged petroleum-polluted area of the Yellow River Delta.","authors":"Chang Zhou, Wenfang Wen, Lei Ji, Fanyong Song, Yingna Xing, Qi Li, Tianyuan Li, Xiaowen Fu","doi":"10.1007/s11274-026-05297-y","DOIUrl":"10.1007/s11274-026-05297-y","url":null,"abstract":"<p><p>Petroleum hydrocarbon pollutants pose a significant threat to the ecological security of oilfields. In these contaminated habitats, Suaeda salsa is a dominant halophyte of the coastal wetlands and oilfields, which has shown potential in remediation of petroleum polluted saline soils. However, the role of plant-associated microbial communities in pollutant attenuation remains poorly understood, particularly regarding niche-specific responses within the root zone. In this study, bacterial community structures associated with the halophyte Suaeda salsa in China's Yellow River Delta were investigated across three ecological niches comprising the endophytic tissues, rhizosphere soils, and bulk soils. A total of 54 samples from 6 sites were collected and analyzed using high-throughput absolute quantification sequencing and physicochemical analyses. Results demonstrated that petroleum hydrocarbons were the primary environmental drivers shaping bacterial community structure across all niches. Comparisons among ecological niches indicated that the rhizosphere effect further promoted the selection and enrichment of specific bacterial taxa, especially the genus Sphingomonas. Contrasting ecological strategies between niches were clearly resolved by co-occurrence network analysis, which showed highly connected networks in rhizosphere communities and modular structures in endophytic ones. Functional predictions further indicated niche-specific metabolic specialization, with endophytic communities enhancing xenobiotic degradation pathways and rhizosphere communities upregulating motility-related functions. These findings reveal the niche-dependent assembly and functional specialization of root-zone microbiomes under petroleum stress, thereby advancing our understanding of plant-microbe adaptive strategies in contaminated ecosystems.</p>","PeriodicalId":23703,"journal":{"name":"World journal of microbiology & biotechnology","volume":"42 10","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements in medium chain fatty acids biosynthesis from organic waste: current state, challenges and future prospects.","authors":"Yunhui Pu, Yang Luo, Dan Xu, Jialing Tang, Qingyuan Wang, Abdelfatah Abomohra","doi":"10.1007/s11274-026-05291-4","DOIUrl":"10.1007/s11274-026-05291-4","url":null,"abstract":"<p><p>Microbial conversion of organic waste into medium chain fatty acids (MCFAs) as the promising strategy to simultaneously achieve waste treatment and resource recovery has attracted increasing attentions in recent years. This review extensively summarized the organics conversion process, key influencing factors and emerging innovative strategies to enhance the MCFAs production. Moreover, the economic feasibility, challenges and research perspectives were also discussed. During the MCFAs production from organic waste, microorganisms involved in hydrolysis, acidogenesis and chain elongation processes coexist and collaborate to realize substrate conversion. Although competitive pathways such as methanogenesis, excessive ethanol oxidation and acrylate pathway disperse the carbon flow, adding chemical inhibitors, adjusting operation parameters and selecting suitable substrates can effectively suppress these competitive processes and promote the MCFA yield. Substrate properties, operational conditions and microbial community are critical factors influencing MCFAs biosynthesis. In addition, strategies such as exogenous additives, co-fermentation, electro-fermentation and microbial strengthening are feasible methods to boost MCFAs production. Furthermore, techno-economic assessment confirmed that MCFAs biosynthesis from organic waste is an economically feasible approach, but low MCFA yield, system instability and restriction of system scale-up are the main challenges for industrial application. This review provided useful information to carbon recovery from organic wastes and technique development.</p>","PeriodicalId":23703,"journal":{"name":"World journal of microbiology & biotechnology","volume":"42 10","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent progress in microbial production of D-aspartate.","authors":"Daiki Imanishi, Le Vi Pham, Shouji Takahashi","doi":"10.1007/s11274-026-05296-z","DOIUrl":"https://doi.org/10.1007/s11274-026-05296-z","url":null,"abstract":"<p><p>D-Aspartate (D-Asp) is a bioactive compound involved in neuroendocrine regulation and reproductive function in animals, including humans, with tissue-protective effects reported in experimental models, and has potential applications as a raw material for pharmaceuticals and functional food ingredients. It is also used as a side-chain precursor for semisynthetic antibiotics. An established industrial process for D-Asp uses enzymatic conversion by immobilized microbial cells with chemically synthesized D,L-Asp as the starting material and is constrained by dependence on chemical feedstock synthesis. Sustainable alternatives have therefore attracted attention: whole-cell bioconversion of exogenously supplied L-Asp has been demonstrated, whereas de novo production from a renewable carbon source has not yet been reported. This mini-review briefly notes the physiological and industrial contexts that motivate microbial production, and then focuses on the functions, biosynthesis, metabolism, and transport of D-Asp in microorganisms. We further discuss the screening of high-D-Asp-producing microorganisms using a high-throughput colorimetric assay based on D-aspartate oxidase, together with the molecular and cultivation characteristics of the strains identified. These studies indicate that racemization mediated by aspartate racemase, precursor supply via L-asparaginase, competing metabolism associated with bifunctional aspartate aminotransferase, and pH control during cultivation influence extracellular D-Asp accumulation; the contribution of membrane transport remains unresolved. Finally, we highlight the identification of D-Asp exporters, metabolic engineering of production strains, and optimization of cultivation processes as key future priorities for establishing a sustainable and reproducible fermentation platform for D-Asp production.</p>","PeriodicalId":23703,"journal":{"name":"World journal of microbiology & biotechnology","volume":"42 10","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13631041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative genomics of nitrogen acquisition and assimilation gene-family copy-number architecture across chlorophytes.","authors":"Prabhaharan Renganathan","doi":"10.1007/s11274-026-05304-2","DOIUrl":"10.1007/s11274-026-05304-2","url":null,"abstract":"<p><p>Nitrogen acquisition and assimilation determine nitrogen availability for algal growth and metabolism; however, their gene-family organization across chlorophytes remains poorly resolved. We examined 10 gene families (NiR, NR, NRT, AMT, GS, GOGAT, GDH, ASN, CPS-L, and CPS-S) in 30 chlorophyte genome assemblies using family-specific sequence-based curation. The assemblies represented 26 biological species after taxonomic standardization and pseudoreplication control. One representative assembly per species defined the primary dataset (D1; n = 26), with BUSCO C ≥ 80% (D2; n = 22) and C ≥ 90% (D3; n = 18) subsets used for genome-completeness sensitivity analyses. A BUSCO-based species phylogeny was used to visualize copy-number patterns relative to relationships among sampled taxa. AMT and NRT showed the broadest copy-number distributions, whereas NiR and the CPS subunits were predominantly single-copy. After normalization for the unequal number of families in each module, nitrogen acquisition had a higher copy-number per family than intracellular assimilation in D1 (Wilcoxon W = 8, p = 4.93 × 10^- 5), and this difference remained significant in D2 and D3. Of 45 pairwise gene-family associations in D1, none remained significant after Benjamini-Hochberg correction; isolated FDR-supported associations in D2 and D3 were not consistent across datasets. These results show heterogeneous nitrogen gene-family architecture across chlorophytes and indicate that the principal descriptive copy-number patterns were stable to genome-completeness filtering. The curated dataset, reproducibility package, and phylogenetic visualization framework provide a basis for further functional and gene-family evolutionary analyses.</p>","PeriodicalId":23703,"journal":{"name":"World journal of microbiology & biotechnology","volume":"42 10","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbial valorization of pomegranate peel pectin into pectic oligosaccharides with selective anticancer activities: in vitro and in silico evaluation.","authors":"Zahra Ghobadi, Afrouzossadat Hosseini-Abari, Hamed Amini-Rourani, Mohammad J Taherzadeh","doi":"10.1007/s11274-026-05298-x","DOIUrl":"10.1007/s11274-026-05298-x","url":null,"abstract":"<p><p>Pomegranate peel, a major by-product of processing, is rich in water-soluble pectin made of D-galacturonic acid units with α (1-4) linkage. Efficiently converting pomegranate peel into safe bioactive principles minimizes waste in the fruit industry and opens new avenues in functional foods. In this work, pomegranate pectin was enzymatically depolymerized with extracellular pectinases from Streptomyces hydrogenans YAM1 to generate pectic oligosaccharides (POS). Products were characterized by TLC and LC-ESI-MS, which indicated unsaturated mono-, di-, and trigalacturonic acids among the main species. Antioxidant activity was maximal at 5 mg mL⁻¹, as detected by the DPPH assay. The anticancer effects of the obtained POS were evaluated by assessing the viability of breast cancer (MCF-7), colorectal adenocarcinoma (Caco2), and neuroblastoma (SH-SY5Y) cells using MTT and flow cytometry assays. Cytotoxicity was also evaluated on normal cells (L929 and HUVEC). The results revealed that at 30 mg mL⁻¹, POS reduced the viability of MCF-7, Caco-2, and SH-SY5Y cancerous cells to < 20% while exhibiting no significant toxicity toward L929 and HUVEC normal cells. The observed efficacy against various cancer cells, without inducing cytotoxicity in healthy cells, distinguishes this compound from other anticancer agents. In the theoretical evaluation using the MM/PBSA method, the most suitable compounds were tetra-galacturonic acid and Δ4,5-unsaturated tri-galacturonate, whose binding free energies to the active site of the Gal-3 receptor were - 128.38 ± 21.51 kJ/mol and - 124.16 ± 23.16 kJ/mol, respectively. These findings support its potential as a unique nutritional compound for preventing and controlling cancer cell growth, advancing the development of next-generation functional pharmaceutical supplements.</p>","PeriodicalId":23703,"journal":{"name":"World journal of microbiology & biotechnology","volume":"42 10","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring whole-genome analysis of a gamma-aminobutyric acid -producing marine Lactiplantibacillus plantarum: genomic insights into neuroactive and probiotic potential.","authors":"Eman H Zaghloul","doi":"10.1007/s11274-026-05275-4","DOIUrl":"10.1007/s11274-026-05275-4","url":null,"abstract":"<p><p>GABA-producing lactic acid bacteria are gaining attention as psychobiotics capable of influencing the microbiota-gut-brain axis, yet marine-derived strains remain poorly characterized. Here, the complete genomic characterization is reported for the marine strain Lactiplantibacillus plantarum EI6, focusing on its probiotic potential, GABA production, and safety. The 3.3 Mb genome (44.5% GC) encodes multiple probiotic-associated genes for acid/bile tolerance, adhesion, and stress response (including heat and cold-shock adaptation), antioxidant activity, and immunomodulation. Genome mining identified the glutamate decarboxylase system (gadB), and GABA production was experimentally confirmed by TLC and HPLC analysis, with a production level of 0.96 g/L. The genome also contains putative bacteriocin gene clusters (plantaricins and sactipeptides) and secondary metabolite BGCs (terpenes, RiPP-like, T3PKS). Safety analysis revealed no major virulence factors or antibiotic resistance genes, supporting a non-pathogenic profile. These findings position L. plantarum EI6 as a promising safe potential psychobiotic candidate for neuroactive and functional food applications.</p>","PeriodicalId":23703,"journal":{"name":"World journal of microbiology & biotechnology","volume":"42 10","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}