Veterinary and comparative oncology最新文献

{"title":"Assessment of Clinical and Immunological Factors of Local Recurrence in Canine Soft Tissue Sarcoma.","authors":"Kazuki Mizuta, Helene Philibert, Arata Matsuyama","doi":"10.1111/vco.70111","DOIUrl":"https://doi.org/10.1111/vco.70111","url":null,"abstract":"<p><p>Canine soft tissue sarcomas (STSs) are locally invasive tumours, making local recurrence a major clinical challenge. Time to recurrence (TTR) and associated immune factors remain poorly characterized. This study aimed to characterize the immune microenvironment of canine STS and identify factors associated with TTR. Medical records from 27 dogs with STS that recurred after surgery were reviewed. Histopathological, transcriptomic, and immunological analyses were performed in a tissue-available subcohort of 20 dogs. Immune-related gene expression was characterized using the NanoString canine IO panel. Tumour-infiltrating immune cells and tertiary lymphoid structures (TLSs) were assessed immunohistochemically using CD3, CD20, and FoxP3. Associations with TTR were evaluated using Cox proportional hazards models and log-rank tests. Median TTR was 358 days. Age and tumour location were associated with TTR in univariable analyses of the full cohort, but neither age nor the overall location effect remained significant when analysed together. Higher NOD2 expression and Cluster 1 assignment were associated with shorter TTR across exploratory multivariable models. Cluster 1 tumours exhibited abundant lymphocyte infiltration and enrichment of immunosuppressive pathways, whereas Cluster 2 tumours demonstrated lower immune infiltration and proinflammatory signatures. TLS-positive tumours had greater lymphocyte infiltration, with FoxP3+ cells accumulated within TLSs. Paired recurrent tumours contained significantly more large TLSs than primary tumours. Higher NOD2 expression and an immunologically active but suppressed tumour phenotype were associated with shorter TTR, whereas the association with anatomical location was model-dependent. Regulatory T cells and TLSs may contribute to the immune landscape associated with local recurrence and warrant further investigation as potential therapeutic targets.</p>","PeriodicalId":23693,"journal":{"name":"Veterinary and comparative oncology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feline Mammary Carcinomas: Clinical Perspectives on Diagnosis, Staging, Treatment and Prognosis.","authors":"Gonçalo N Petrucci, Luís Lobo, Felisbina Pereira Queiroga","doi":"10.1111/vco.70109","DOIUrl":"https://doi.org/10.1111/vco.70109","url":null,"abstract":"<p><p>Feline mammary carcinomas remain a major therapeutic and prognostic challenge in veterinary oncology because they combine high malignant potential, early dissemination, and substantial heterogeneity in clinicopathologic behaviour. This review summarizes current clinical knowledge on epidemiology, risk factors, diagnostic work-up, staging, treatment, and prognostic assessment of feline mammary carcinomas, highlighting areas of consensus and persistent controversies. Progress in care will require prospective, multicentre studies built on harmonized staging and pathology reporting, enabling risk-adapted treatment pathways that are both evidence-based and clinically actionable.</p>","PeriodicalId":23693,"journal":{"name":"Veterinary and comparative oncology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Life Shapes Owner Decision-Making in Canine Cancer Care: Insights From Large-Scale Online Discourse.","authors":"Georgina Anne Tarrant, Andi Flory, Taranpreet Singh Rai, Andrea Wright, Travis Lee Street, Kevin Wells","doi":"10.1111/vco.70112","DOIUrl":"https://doi.org/10.1111/vco.70112","url":null,"abstract":"<p><p>Canine cancer imposes substantial emotional, financial and decisional burden on owners navigating complex referral pathways and treatment options. Understanding how owners experience and interpret these pathways is essential to improving care delivery. We conducted a retrospective social media listening study using Pulsar Platform to retrieve public Anglophone posts relating to canine cancer across multiple platforms. After cleaning, de-duplication and zero-shot large language model relevance filtering (accuracy 88%-99%, F1 93%-98%, with precision up to 99% on Reddit), 11 878 posts were analyzed (of those that could be geolocated, most originated from the USA). Sentiment and emotion classification, thematic extraction and non-negative matrix factorization topic modelling were applied. Pre-specified subsets examined cost-focused (n = 2008), referral-focused (n = 341) and steroid-focused (n = 438) discourse. Overall, negative sentiment predominated (66%), with sadness the most frequent emotion (64%). Across platforms, quality of life (QoL) functioned as the primary decision-making framework, operationalized through appetite, mobility, comfort, engagement and \"good days\". Referral narratives highlighted delays, diagnostic sequencing uncertainty, travel burden and perceived gatekeeping within referral pathways. Financial constraint frequently shaped treatment feasibility, influencing decisions regarding chemotherapy, surgery, steroid-only palliation and euthanasia. Steroids were often described as a palliative bridge or cost-constrained alternative when advanced oncology care was inaccessible. General practise (GP) veterinarians were consistently referenced as trusted information anchors, influencing referral uptake and treatment trajectories. Topic modelling suggests a cancer-care pathway experienced as structurally constrained despite strong owner willingness to pursue treatment. QoL consistently supersedes cure as the dominant evaluative metric. Earlier cost transparency, clearer shared-care communication and strengthened GP-oncologist coordination may reduce decisional distress and help mitigate avoidable barriers to specialist care.</p>","PeriodicalId":23693,"journal":{"name":"Veterinary and comparative oncology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148901021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of the IlluminOss Photodynamic Bone Stabilisation System Following Stereotactic Body Radiation Therapy for Limb-Sparing in Six Dogs With Presumptive Appendicular Osteosarcoma.","authors":"Emily A Pope, Vincent A Wavreille, Janis L Lapsley, Eric M Green, William C Kisseberth, Robert Rabiner, Laura E Selmic","doi":"10.1111/vco.70082","DOIUrl":"10.1111/vco.70082","url":null,"abstract":"<p><p>Osteosarcoma is the most common primary bone tumour in dogs, with approximately 75% of cases occurring in the appendicular skeleton. Standard-of-care therapy consists of limb amputation followed by carboplatin chemotherapy. A minority of dogs have limb-sparing treatments including stereotactic body radiation therapy (SBRT) or surgery. SBRT has a high incidence of pathologic fracture (41%-80% of cases) following treatment, which often results in amputation or euthanasia. Prophylactic bone stabilisation following SBRT has not been recommended due to high complication rates. The IlluminOss system (IS) is an intramedullary implant consisting of a light-curable polymer within an inflatable balloon catheter, which is approved in humans for traumatic fractures and prevention of fractures secondary to bone metastases. We performed a study to assess the safety and feasibility of using the IS following SBRT in six dogs with suspected appendicular osteosarcoma. The IS was placed the day after completion of SBRT. Five of six dogs received adjuvant carboplatin chemotherapy. The IS was well tolerated with no implant-associated infections or immediate post-operative complications occurring. Pathologic fractures occurred in four dogs with a median fracture-free interval of 107 days. Three dogs ultimately underwent amputation due to pathologic fractures. No other post-operative complications occurred. The median survival time was 156 days. These findings suggest that the IS may be a palliative option for dogs following SBRT, but further research to optimise use in the dog and evaluation of the use of the IS with ancillary fixation is necessary.</p>","PeriodicalId":23693,"journal":{"name":"Veterinary and comparative oncology","volume":" ","pages":"611-620"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13456591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148228546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Volumetric Modulated Arc Therapy and Fixed-Field Intensity-Modulated Radiotherapy for Canine Prostatic Carcinoma Using a 4.3 Gy × 10-Fraction Protocol: A Dosimetric Planning Study.","authors":"MyoungHun Kim, InSeong Jeong, KiDong Eom, JaeHwan Kim","doi":"10.1111/vco.70073","DOIUrl":"10.1111/vco.70073","url":null,"abstract":"<p><p>Advancements in radiotherapy, including intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT), have reduced radiation-induced toxicities, enabling hypofractionated protocols to be feasible for treating intrapelvic tumours in dogs. This study aimed to determine the optimal planning technique for canine prostatic carcinoma using a radiotherapy protocol delivering 43 Gy in 10 fractions. Four techniques were compared-two full arcs (2FA), two partial arcs (2PA), 9-field IMRT (9F) and 7-field IMRT (7F). Computed tomography datasets from 22 dogs were analysed. While the conformity index did not differ significantly among techniques, IMRT demonstrated significantly lower homogeneity index than VMAT. IMRT yielded the lowest rectal normal tissue complication probabilities (NTCPs), maximum dose (Dmax) and V45, whereas 2PA achieved the lowest mean dose (Dmean) and V10, V15, V20, V25 and V30. Additionally, IMRT showed significantly lower NTCPs and V20, V25 and V30 for the colon; NTCPs and V20, V25, V30 and V35 for the small intestine; and Dmax, V20, V25 and V45 for the bladder. For the urethra, IMRT showed the lowest Dmax and V45, whereas 2PA demonstrated the lowest Dmean and V10, V15 and V20. The spinal cord (Dmean, V10, V15) and cauda equina (Dmean, Dmax, V10, V15 and V20) were best spared with 2PA. However, 2PA resulted in the highest femoral head NTCPs, Dmean, Dmax and V20, V25 and V30. IMRT showed significantly greater monitor units and beam-on time than VMAT, especially with 9F. In conclusion, under the predefined and unaltered planning objective and constraints used in this study, IMRT showed more favourable OAR sparing and improved dose homogeneity than VMAT. Among the IMRT techniques, 7F may be preferred over 9F due to reduced beam-on time and monitor units. However, these findings reflect the specific equipment, planning setting and optimisation approach applied in this study and different planner, systems or optimisation strategies may yield different results. Therefore, treatment planning should be individualised according to patient-specific dosimetric characteristics.</p>","PeriodicalId":23693,"journal":{"name":"Veterinary and comparative oncology","volume":" ","pages":"515-531"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13456614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Raman Spectroscopy for Differentiating High- and Low-Grade Canine Cutaneous Mast Cell Tumours.","authors":"José Catarino, Susana Silva, Susana Novais, Joana Santos, Rita Payan-Carreira, Pedro Faísca, Joana Reis","doi":"10.1111/vco.70083","DOIUrl":"10.1111/vco.70083","url":null,"abstract":"<p><p>Canine cutaneous mast cell tumours (MCTs) demonstrate variable clinical behaviour. Histological grading remains the primary prognostic approach, but some low-grade tumours behave aggressively, and interobserver variability persists. This underscores the need for complementary and objective biomarkers. Raman spectroscopy (RS) is a non-destructive optical technique based on the inelastic scattering of monochromatic light capable of detecting subtle biochemical changes in tissues. This exploratory study evaluates whether RS could differentiate low-grade from high-grade cutaneous MCTs based on characteristic vibrational signatures. Eighteen canine cutaneous mast cell tumours were graded according to the Kiupel two-tier system, comprising 10 low-grade and 8 high-grade cases. Formalin-fixed tumour samples were analysed, yielding a total of 68 Raman spectra. Spectra were acquired with a 785 nm laser, pre-processed using baseline correction, and normalized to the 1007 cm^-1 phenylalanine band. Data normality was tested with the Shapiro-Wilk test, and group comparisons used the Mann-Whitney U test (α = 0.05). The 1007 cm^-1 band showed no significant difference between Low- and High-Grade tumours (p = 0.068), validating its use for normalization. Conversely, the 860 cm^-1 tyrosine-associated band was significantly higher in high-grade tumours (p = 0.033). Ratios normalized to the 1007 cm^-1 peak consistently discriminated between grades, with significantly higher values in low-grade tumours across multiple spectral regions-particularly 1007/1299 and 1007/1301-1320 (all p < 0.05). Overall, RS identified distinct biochemical fingerprints between tumour grades in canine cutaneous MCTs, especially in spectral regions associated with amino acids, lipids, and nucleic acids. These findings support the potential of RS as a complementary tool for MCT characterization and encourage further validation in larger cohorts with clinical outcome data.</p>","PeriodicalId":23693,"journal":{"name":"Veterinary and comparative oncology","volume":" ","pages":"621-630"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13456598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abstracts from the ESVONC Annual Congress, 21-23 May 2026.","authors":"","doi":"10.1111/vco.70095","DOIUrl":"10.1111/vco.70095","url":null,"abstract":"","PeriodicalId":23693,"journal":{"name":"Veterinary and comparative oncology","volume":"24 Suppl 2 ","pages":"4-26"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149018175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical Exposures, DNA Methylation and Whole Blood DNA Damage in Pet Golden Retrievers.","authors":"Ashleigh N Tindle, Mark E Berres, Lauren Baker, Zhuonan Wu, Brenna Swafford, Julia Labadie, Lauren A Trepanier","doi":"10.1111/vco.70066","DOIUrl":"10.1111/vco.70066","url":null,"abstract":"<p><p>Canine multicentric lymphoma (CL) is a common and typically fatal cancer among dogs. Although certain breeds have a higher incidence of CL, its environmental risk factors remain uncertain. Exposures to herbicides and volatile organic compounds (VOCs) associate with non-Hodgkin lymphoma in people. These exposures also correlate with measurable in vivo DNA strand breaks in dogs, even at estimated systemic concentrations that do not reach genotoxic thresholds. Herbicides and VOCs can also exert genotoxicity through differential DNA methylation. We therefore hypothesised that higher chemical exposures would be associated with differential global and gene-specific methylation in the blood of pet golden retrievers, and that differential gene-specific methylation would be further associated with measured DNA strand breaks and oxidised DNA damage. We performed Oxford Nanopore sequencing in 24 of 60 dogs from a recent case-control study within the Golden Retriever Lifetime Study cohort, selected based on the highest and lowest quintiles of estimated aggregate herbicide and VOC exposures. Contrary to our initial hypothesis, higher estimated chemical exposures were associated with relatively lower promoter methylation of antioxidant genes (median 0.335 versus 0.374; p = 0.007) and 8-oxoguanine DNA repair genes (median 0.254 versus 0.294; p = 0.007). This pattern could represent a compensatory response to chemical exposures rather than a driver of DNA damage. Follow-up studies are needed to determine whether these modest promoter methylation differences correspond to biologically meaningful increases in gene expression, antioxidant status and DNA repair capacity.</p>","PeriodicalId":23693,"journal":{"name":"Veterinary and comparative oncology","volume":" ","pages":"433-443"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13456616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147723729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cabazitaxel Demonstrates Potent Antitumour Activity Against Canine Large-Cell Alimentary Lymphoma In Vitro and In Vivo.","authors":"Kosei Sakai, Nana Suzuki, Masaru Furuya, Hiroshi Ohta, Satoshi Kameshima, Shunsuke Shimamura","doi":"10.1111/vco.70080","DOIUrl":"10.1111/vco.70080","url":null,"abstract":"<p><p>Canine large-cell alimentary lymphoma (LCAL) is an aggressive malignancy with limited effective treatment options and a poor prognosis. In a preliminary drug screening study using three canine LCAL cell lines (CLC, Ema, and Nody-1), the taxane cabazitaxel (CBZ) was identified as a promising candidate drug. This study aimed to evaluate the antitumour effects of CBZ in vitro and in vivo and determine its potential as a novel therapeutic candidate for canine LCAL. Cell viability, tubulin polymerisation, cell cycle distribution, and apoptosis were assessed in CLC, Ema, and Nody-1 cells following treatment with CBZ or vehicle control. In addition, the effect of CBZ was evaluated in a xenotransplantation mouse model established using CLC cells. CBZ reduced cell viability across all cell lines in a dose-dependent manner, with sub-nanomolar half-maximal inhibitory concentrations. A tubulin polymerisation assay demonstrated that CBZ increased polymerised tubulin levels, indicating microtubule stabilisation. CBZ treatment induced G2/M cell cycle arrest and significantly increased apoptotic cell populations, accompanied by decreased procaspase-3 levels and increased cleaved caspase-3 expression. In vivo, CBZ treatment reduced ascites accumulation and significantly prolonged survival relative to the vehicle control. These findings suggest that CBZ induces G2/M cell cycle arrest and caspase-dependent apoptosis through tubulin stabilisation and suppresses tumour progression in vivo. CBZ represents a promising therapeutic candidate for canine LCAL.</p>","PeriodicalId":23693,"journal":{"name":"Veterinary and comparative oncology","volume":" ","pages":"593-600"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13456607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148144681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Messenger RNA From Canine Cytology Lymph Node Specimens Can Be Utilised for Gene Expression Profiling Using Digital RNA Counting.","authors":"McKenzie Olsen, Emily Rout, Kelly Hughes, Janna Yoshimoto, Anne Avery, R Adam Harris","doi":"10.1111/vco.70078","DOIUrl":"10.1111/vco.70078","url":null,"abstract":"<p><p>Gene expression profiling (GEP) is being used with increasing frequency to characterise canine tumours, but canine samples are often not collected in a medium to preserve RNA. Cytology samples from human tumours have been shown to provide adequate RNA for GEP using NanoString nCounter technology, suggesting a similar approach might be viable for canine samples. Determine the quantity and quality of RNA extracted from canine cytology slides, evaluate the time frame for RNA integrity and assess the utility of performing GEP with extracted RNA. Cytological specimens were derived from reactive lymph nodes (n = 10) and lymphoma cases (n = 34) and characterised via flow cytometry or PCR for antigen receptor rearrangements. RNA was extracted from stained and unstained lymph node cytology slides using a RNeasy Mini Kit and subsequently evaluated for quality and quantity. GEP was carried out using nCounter technology with the NanoString Canine IO Panel. Extracted RNA from lymphoma and reactive cytology samples generated concentrations ranging from 27.5 to 543.9 ng/μL (median: 168.5 ng/μL; interquartile range (IQR): 108.15-275.95 ng/μL). RNA integrity numbers (RINs) ranged from 1.0 to 7.2 (median: 2.9; IQR: 2.10-4.45) and DV200 values ranged from 50.5% to 93.2% (median: 81.65%; IQR: 71.95%-87.85%). RIN and DV200 values were highest for extractions within 7 days of sample collection. GEP revealed overexpression of 17 genes in lymphoma samples such as MYC, TERT and BRCA2. Canine lymph node cytologic specimens provide sufficient RNA quality for GEP. The nCounter Canine IO Panel demonstrates the utility of cytology specimens for evaluating gene expression.</p>","PeriodicalId":23693,"journal":{"name":"Veterinary and comparative oncology","volume":" ","pages":"568-577"},"PeriodicalIF":1.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13456604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148043867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}