Julya Nathalya Felix Chaves, Mathias Reginatto Wrzesinski, Julia da Silva Rauber, Denis Antonio Ferrarin, Marcelo Luis Schwab, Glaucia Denise Kommers, Mariana Martins Flores, Ana Paula da Silva, Angel Ripplinger, Diego Vilibado Beckmann, Alexandre Mazzanti
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Neurological Recovery in 14 Cats With Epidural Lymphoma Treated With Chemotherapy.
The purpose of this study was to evaluate the rate and timing of neurological recovery in cats with epidural lymphoma who were treated with chemotherapy. The study included cats with various degrees of neurological impairment, confirmed diagnosis of lymphoma and spinal cord involvement. At the start of treatment, of the 14 cats diagnosed with lymphoma, 14.3% (n = 2) had ambulatory paraparesis, 14.3% (n = 2) had non-ambulatory paraparesis, 7.1% (n = 1) paraplegia with deep nociception, 50% (n = 7) were paraplegic with absent deep nociception and 14.3% (n = 2) had non-ambulatory tetraparesis. The chemotherapy treatment given was COP in 10 cats, COP and CHOP in 2 cats and CHOP in 2 cats. The number of chemotherapy sessions needed for neurological recovery varied from 1 to 4, with a total of 1-13 sessions per cat. The rate of neurological recovery was satisfactory in 83.3% (10/12) of the cats. This study indicates that cats with epidural lymphoma treated with chemotherapy have an 83.3% likelihood of partial neurological recovery and a 50% chance of full neurological recovery within a period of 7-28 days, regardless of the level of neurological impairment.
期刊介绍：
Veterinary and Comparative Oncology (VCO) is an international, peer-reviewed journal integrating clinical and scientific information from a variety of related disciplines and from worldwide sources for all veterinary oncologists and cancer researchers concerned with aetiology, diagnosis and clinical course of cancer in domestic animals and its prevention. With the ultimate aim of diminishing suffering from cancer, the journal supports the transfer of knowledge in all aspects of veterinary oncology, from the application of new laboratory technology to cancer prevention, early detection, diagnosis and therapy. In addition to original articles, the journal publishes solicited editorials, review articles, commentary, correspondence and abstracts from the published literature. Accordingly, studies describing laboratory work performed exclusively in purpose-bred domestic animals (e.g. dogs, cats, horses) will not be considered.
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