Vector borne and zoonotic diseases最新文献

{"title":"A Comparison of Clinical and Laboratory Features of Crimean-Congo Hemorrhagic Fever in Children and Adults: A Retrospective Single-Center Cohort Study and Literature Review.","authors":"Ilkay Bozkurt, Emine H Erdeniz, Matthew J Riley, Levent Şensoy, Nick J Beeching, Sema Aydogdu, Hakan Leblebicioglu, Gulay Korukluoglu, Tom E Fletcher","doi":"10.1089/vbz.2024.0066","DOIUrl":"10.1089/vbz.2024.0066","url":null,"abstract":"<p><p><b><i>Background:</i></b> Crimean-Congo hemorrhagic fever (CCHF) is a major emerging infectious disease threat, and children are reported to have a milder disease course compared with adults, in contrast to other viral hemorrhagic fevers. The aim of this study was to compare adult and pediatric patients with CCHF to improve understanding of pathogenesis and the natural history of the disease. <b><i>Materials and Methods:</i></b> A retrospective analysis of all children and adults admitted with confirmed CCHF between 2011 and 2020. Epidemiological, clinical, and laboratory features were collated on proformas, together with clinical management details. The Severity Grading Score (SGS) system was used to stratify mortality risk. Data from children were compared with adults in the same center and with other published pediatric cohort studies. <b><i>Results:</i></b> A total of 47 children with a median (ranges) age of 14 (2-17) years and 176 adults with a median (ranges) age of 52 (18-83) years with confirmed CCHF were included. The most frequent symptoms in adults were fever, muscle-joint pain, headache, nausea, and vomiting; the most frequent in children were fever, anorexia, nausea, vomiting, and abdominal pain. Adults had lower lymphocyte and platelet counts and higher liver transaminase and creatinine levels than children. SGS values were lower in children, but 97.9% children received ribavirin compared with 8.5% of adults (<i>p</i> < 0.001), and they had associated longer median lengths of hospital admission (10 vs. 7 days, <i>p</i> < 0.001). Mortality of 1 out of 47 (2.1%) children was similar to 11 other cohorts reported in Türkiye and lower than 13.1% in adults (23/176) in the same center (<i>p</i> = 0.059). <b><i>Conclusions:</i></b> Children have lower CCHF-related mortality, less severe disease, and different clinical syndromes at presentation. The majority of published case definitions for screening for CCHF in the main endemic countries do not differentiate between adults and children and omit four of the five most common presenting features in children.</p>","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"81-91"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishment of Animal Infection Model of <i>Spirometra Mansoni</i> and Identification of <i>Spirometra Mansoni</i> by Enzyme-Linked Immunosorbent Assay.","authors":"Anqi Luo, Shuyu Chen, Mingye He, Xiaoruo Tan, Zhikang Li, Wei Liu, Yisong Liu","doi":"10.1089/vbz.2024.0051","DOIUrl":"10.1089/vbz.2024.0051","url":null,"abstract":"<p><p><b><i>Objective:</i></b> <i>Spirometra mansoni</i> is a crucial zoonotic parasite. Its larvae are more harmful than adult worms due to their ability to migrate through the host's tissues and organs. Therefore, it is necessary to establish an animal model of spargana for observing pathological changes and exploring diagnostic techniques. <b><i>Methods:</i></b> In this study, we infected Kunming mice and cats without any pathogens by feeding sparganum (with the scolex and neck) in order to understand the infection cycle of <i>S. mansoni</i> and explore the preservation host of sparganosis. The infection of <i>S. mansoni</i> was determined by fecal detection and enzyme-linked immunosorbent assay (ELISA). <b><i>Results:</i></b> In the model of cats, the eggs of <i>S. mansoni</i> were found in the feces ten days after the infection. The serum-specific IgG antibodies against <i>S. mansoni</i> were positive in experimental groups (mice and cats), and after sixty days, the S. mansoni worms isolated from experimental groups were collected. <b><i>Conclusion:</i></b> In conclusion, the experimental results show that mice and cats can be stably infected with S. mansoni through feeding sparganum (with the scolex and neck). The infection method of this study has the potential to establish a practical model for investigating the diagnostic process of <i>S. mansoni</i>, laying the groundwork for application and development. ELISA was used to diagnose mice and cats infected with sparganosis mansoni, providing a case for non-invasive identification of animal sparganosis.</p>","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"133-141"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142509149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antiparasitic Effects of Niosomal Formulations of Curcumin and Silymarin Against <i>Toxoplasma gondii In Vitro</i>.","authors":"Hiba Riyadh Al-Abodi","doi":"10.1089/vbz.2024.0044","DOIUrl":"10.1089/vbz.2024.0044","url":null,"abstract":"<p><p><b><i>Background:</i></b> Toxoplasmosis is caused by infection with <i>Toxoplasma gondii.</i> No Symptoms in healthy people. Notably, very dangerous symptoms in immunocompromised, or patients with immune diseases. Previous research has shown that the parasite's resistance to drugs continues to emerge and has indicated this resistance as a cause for concern. In this context, researchers have a great responsibility to search for alternative treatments, as well as to develop existing ones. Essentially, this improves the therapeutic efficacy of drugs and prevents the emergence of resistance to them. The present study aims to evaluate antitoxoplasma effects of niosomal loaded curcumin and silymarin and their synergistic effects with clindamycin against <i>T. gondii</i> RH strain <i>in vitro</i>. <b><i>Materials and Methods</i></b>: Experiments were conducted on the tachyzoites of <i>T. gondii</i> RH-strain, based on: the free and nieosomal compounds of curcumin and silymarin, in addition to the drug clindamycin. Data were collected to estimate parasite viability during exposure to the therapeutic compounds under study using a special MTT assay ((3-(4, 5-dimethylthiazolyl-2)-2,5-diphenyltetrazolioum bromide) assay: is a colorimetric assay for measuring cellular growth) kit provided by (Bio Idea Company, Tehran, Iran). Hence, the effect of the therapeutic compounds on the parasite load was studied using the quantitative molecular technique real-time PCR. <b><i>Results:</i></b> The results indicate that the combination of N-silymarin and N-curcumin with clindamycin has active synergistic effects against <i>T. gondii</i> leading to complete elimination of the parasite. Data revealed that curcumin and silymarin in both their free and nisomal forms had inhibitory effects on the parasite, and minimal toxic effects on normal cells. <b><i>Conclusions</i></b>: The results highlight the successful synergistic effect of clindamycin and the niosomal compounds curcumin and silymarin in completely eradicating the <i>T. gondii</i> RH-strain. This finding contributes positively to the field of safe and effective treatments.</p>","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"125-132"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Burden of <i>Acinetobacter baumannii</i> Among Pet Dogs and Cats with Respiratory Illness Outside the Healthcare Facilities: A Possible Public Health Concern.","authors":"Alaa A Shaker, Ahmed Samir, Hala M Zaher, Khaled A Abdel-Moein","doi":"10.1089/vbz.2024.0082","DOIUrl":"10.1089/vbz.2024.0082","url":null,"abstract":"<p><p><b><i>Background:</i></b> Researchers paid more attention to nosocomial <i>Acinetobacter baumannii</i> in veterinary hospitals worldwide; however, the research scope toward community-acquired <i>A. baumannii</i> infections among animals is largely ignored. Therefore, the current study aimed to investigate the role of diseased dogs and cats suffering from respiratory illness in transmission of community-acquired <i>A. baumannii</i> infection and its public health threat. <b><i>Materials and methods:</i></b> Oral swabs were collected from 154 pet animals with respiratory signs, including 80 cats and 74 dogs (outpatient visits). The obtained swabs were cultured on CHROMagar™ MH Orientation media for isolation of <i>A. baumannii</i>, and identification of suspected isolates was conducted via Gram staining, conventional biochemical tests, and molecular detection of the <i>bla</i>_OXA-51-like gene. Antimicrobial susceptibility testing of <i>A. baumannii</i> isolates was carried out using the disc diffusion method. <b><i>Results:</i></b> Overall, 10 (6.5%) out of 154 diseased pet animals were positive for <i>A. baumannii</i>, where 6 (8.1%) and 4 (5%) dogs and cats were positive, respectively. Multidrug-resistant (MDR) <i>A. baumannii</i> was found in 3.9% of the examined animals. The phylogenetic tree analysis revealed that the obtained sequences from dogs and cats were closely related to human and animal sequences. <b><i>Conclusion:</i></b> The occurrence of MDR <i>A. baumannii</i> among dogs and cats suffering from respiratory illness highlights the potential role of pet animals in the dissemination of MDR <i>A. baumannii</i> in the community.</p>","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"118-124"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Toscana Virus Antibodies in Residents of Bulgaria: A Nationwide Study Following the Pandemic of COVID-19.","authors":"Iva Trifonova, Kim Ngoc, Teodora Gladnishka, Elitsa Panayotova, Evgenia Taseva, Vladislava Ivanova, Iva Vladimirova, Eleonora Kuteva, Iva Christova","doi":"10.1089/vbz.2024.0050","DOIUrl":"10.1089/vbz.2024.0050","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Toscana virus (TOSV) is an arthropod-borne virus transmitted by sandflies and is mainly found in countries around the Mediterranean basin. In this article, we present the findings of a seroprevalence study on TOSV in Bulgaria. We aim to assess the current epidemiological situation regarding TOSV in the country and raise clinical awareness. <b><i>Methods:</i></b> Serum samples (<i>n</i> = 1892) were collected in December 2023. Serological tests were performed using a commercial anti-TOSV ELISA kit. <b><i>Results:</i></b> Specific immunoglobulin G (IgG) antibodies were detected in 6.4% (121/1892) of the participants. A significantly higher seropositivity rate was found in the age group over 65 years compared with the age groups 18-29 and 40-64 (11.8% vs. 3.9% vs. 3.4%), as well as in males compared with females (8.0% vs. 5.3%). The seroprevalence rates in districts ranged from 0% to 18.5%. Higher seropositivity was found in the southern and northern regions. <b><i>Conclusions:</i></b> The seroprevalence rate of TOSV in Bulgaria, found in this study, is a significant decrease compared with the seropositivity rate of 24.5% reported in the country in 2018. The reasons for this are unknown and could possibly be related to the COVID-19 pandemic and the constantly changing environmental conditions. There is also a possibility that the higher seropositivity detected in 2018 together with the rise in clinical cases reported from endemic countries around that time might have been due to an unrecognized TOSV outbreak taking place in this period. Continued clinical awareness and surveillance are necessary for recognition and management of potential cases of TOSV neuroinfection, especially during summer.</p>","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"142-147"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coinfection with Orthohantavirus and <i>Leptospira</i> spp. in Rats Collected from Markets in Indonesia.","authors":"Kozue Miura, James Chambers, Naohiro Takahashi, Harimurti Nuradji, Nlp Indi Dharmayanti, Susanti, Parriantariksina Randusari, Susan M Noor, Rahmat Setya Adji, Muharam Saepulloh, Sumarningsih, Kumiko Yoshimatsu, Nobuo Koizumi","doi":"10.1089/vbz.2023.0170","DOIUrl":"10.1089/vbz.2023.0170","url":null,"abstract":"<p><p><b><i>Background:</i></b> Rats are an important reservoir animal for several zoonotic pathogens worldwide, including hantaviruses and Leptospira spp., which are the causative agents of hemorrhagic fever with renal syndrome, hantavirus cardiopulmonary syndrome, and leptospirosis. Although a previous study indicated a high frequency of antihantaviral antibodies in patients with acute fever in Indonesia, circulating hantaviruses and their reservoir animals in the country remain limited. <b><i>Materials and Methods:</i></b> The presence of hantavirus in rats captured in the urban area of Bogor, Indonesia, from which Leptospira spp. were isolated using PCR, followed by DNA sequencing. Immunohistochemical analyses were performed to detect hantaviral and leptospiral antigens in rat kidney tissues. <b><i>Results:</i></b> Seoul of Orthohantavirus seoulense (SEOV) RNA was detected from 24 of 80 Rattus norvegicus (30%). SEOV and Leptospira coinfection was detected in 10 of 80 rats (12.5%). Immunohistochemistry revealed that hantavirus antigens were positively stained in the interstitial capillaries and cells, whereas Leptospira antigens were stained in the luminal side of the renal tubules. <b><i>Conclusion:</i></b> This study revealed a high prevalence of SEOV and SEOV and Leptospira coinfection among rats in the urban areas of Bogor, Indonesia, indicating a potential risk of rat-borne zoonotic diseases in the area.</p>","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"43-48"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Bartonella</i> Species in Small Mammals in Turkey: <i>Bartonella bilalgolemii</i> sp. nov. Isolated from a Ural Field Mouse (<i>Apodemus uralensis</i>).","authors":"Bekir Çelebi, Rita Zgheib, Ahmet Karataş, Cahit Babür, İbrahim Mehmet Ali Öktem, Ferhat Matur, Mustafa Sözen, Bernard Davoust, Oleg Mediannikov, Pierre-Edouard Fournier","doi":"10.1089/vbz.2024.0026","DOIUrl":"10.1089/vbz.2024.0026","url":null,"abstract":"<p><p><b><i>Background:</i></b> The genus <i>Bartonella</i> is composed of Gram-negative, fastidious, facultative intracellular bacteria that can cause bacteremia in mammals and various disorders in humans. Rodents have been reported as reservoirs of more than 30 <i>Bartonella</i> species, seven of which cause zoonotic infections. <b><i>Materials and Methods:</i></b> In the present study, the isolation of <i>Bartonella</i> sp. was attempted from 150 spleen samples from 13 rodent species (mostly <i>Apodemus</i> species) from three geographically different regions in Turkey. <b><i>Results:</i></b> <i>Bartonella</i> sp. was successfully isolated from 65 of these 150 samples (43%). The prevalences of <i>Bartonella</i> sp. in tested rodents in the regions of Giresun, Yozgat, and Burdur were 68%, 44%, and 16%, respectively. Using polymerase chain reaction/sequence analysis of the citrate synthase-coding gene (<i>gltA</i>), Bartonellaisolates were classified seven species including <i>B. taylorii</i>, <i>B. grahamii</i>, <i>B. birtlesii</i>, <i>B. mastomydis</i>, and three putatively new <i>Bartonella</i> species. We performed further identification techniques for one of the three <i>Bartonella</i> species that were different from the validated <i>Bartonella</i> species according to the <i>gltA</i> sequence analysis. <b><i>Conclusion:</i></b> Here, we report the genomic and phenotypic characterization of <i>Bartonella</i> sp. strain G70 that was isolated from the splenic tissue of an <i>Apodemus uralensis</i> (Pallas 1881), the Ural field mouse, captured in the Giresun region of northeastern Turkey. <i>Bartonella</i> sp. strainG70 (RSKK 22001) was characterized by whole genome and partial gene (<i>gltA</i>, 16S ribosomal RNA) sequencing and comparison, scanning electron microscopy, biochemical tests, and matrix-assisted laser desorption ionization time-of-flight mass spectrometry. This novel <i>Bartonella</i> is a Gram-negative, rod-shaped bacterium and has neither flagella nor pili. The genome from strain G70 was 1,606,969-bp-long with a G + C content of 35.7%. <i>Bartonella rochalimae</i> was found to be the closest phylogenetic relative of strain G70 (OrthoANI = 90.5%, digital DNA-DNA hybridization = 41.4%). We therefore propose that this new species be named <i>Bartonella bilalgolemii</i> sp. nov. with strain G70^T as the type strain.</p>","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"60-70"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brucellosis Coinfecting with Liver Hydatid Cyst: Case Report and Literature Review of Zoonoses Coinfection of Human Brucellosis.","authors":"Dai Peijun, Shen Weiwei, Pu Zhongshu","doi":"10.1089/vbz.2024.0062","DOIUrl":"10.1089/vbz.2024.0062","url":null,"abstract":"<p><p><b><i>Background:</i></b> Brucellosis is a major global public health problem. Brucellosis usually coinfects with zoonoses because of their similar reservoir and infection routes. <b><i>Materials and Methods:</i></b> Here, we present a patient who was diagnosed with coinfecting with liver cyst and brucellosis. <b><i>Results:</i></b> A 57-year-old female farmer was hospitalized with right hip joint pain approximately 4 weeks earlier. The patient reported a history of hydatid cysts and a family history of brucellosis. Abdominal computerized tomography and ultrasonography revealed a liver hydatid cyst. The standard agglutination test titer of Wright's test was 1:100. Computerized tomography and magnetic resonance imaging revealed brucellosis hip arthritis. The patient was treated with a combination of doxycycline, rifampicin, and cefotaxime. The symptoms immediately improved. The patient was well and asymptomatic during the 6-month follow-up. We reviewed the literature on other zoonoses superinfection with brucellosis. <b><i>Conclusion:</i></b> Brucellosis coinfects with multiple zoonosis organisms and poses a serious health threat to humans. Awareness of possible brucellosis coinfection with other zoonoses, especially professionally exposed persons in endemic regions, is warranted.</p>","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"74-77"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathogen and Host Associations of Soft Ticks Collected in South Texas.","authors":"Sarah E Mays Maestas, Lauren P Maestas, Phillip E Kaufman","doi":"10.1089/vbz.2023.0135","DOIUrl":"10.1089/vbz.2023.0135","url":null,"abstract":"<p><p><b><i>Background:</i></b> Soft ticks (Family: Argasidae) are vectors of relapsing fever <i>Borrelia</i> in the United States and are potential vectors of African swine fever virus, a pathogen that could have a devastating effect on the U.S. swine industry if introduced to the U.S. mainland. Much of the tick-borne disease research in the U.S. focuses on hard ticks, and less is known about the ecology of soft ticks. Some soft tick species found in the southern U.S. have a wide host range and may feed on cattle, swine, native and exotic ungulates, small mammals, reptiles, and humans. Because the feeding habit of most soft tick species involves taking short, repeated blood meals that may include multiple host species, pathogen transmission among hosts is a concern both for human and animal health. <b><i>Materials and Methods:</i></b> Sampling was carried out at four locations in south Texas using dry ice traps placed in or near animal burrows and other sheltering cracks and crevasses that may provide refuge for soft ticks. Collected ticks were identified and subsequently screened for <i>Rickettsia</i> and <i>Borrelia</i> species and for host bloodmeal detection using conventional polymerase chain reaction and Sanger sequencing for pathogen and host species identification. <b><i>Results:</i></b> In total, 256 ticks of two Ornithodorinae species were screened. <i>Borrelia</i> species were identified in three samples. Bloodmeal detections were made in 22 tick specimens, representing eight vertebrate host species. <b><i>Conclusions:</i></b> Results demonstrate that the soft tick species detected herein feed on a range of wildlife hosts in south Texas and are associated with agents of human disease.</p>","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"34-42"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating the Landscape of Tick Diversity: Integrating Molecular Approaches for Enhanced Control Measures.","authors":"Donath Damian","doi":"10.1089/vbz.2024.0052","DOIUrl":"10.1089/vbz.2024.0052","url":null,"abstract":"<p><p>The emergence and spread of infectious diseases, particularly zoonotic diseases originating from wildlife, pose significant threats to global health and economy. This review examines the pivotal role of ticks as vectors in transmitting pathogens to humans, livestock, and wildlife and the use of molecular techniques in their identification. Tick infestations result in economic losses through reduced animal productivity, anemia, and quality deterioration of hides. Furthermore, ticks serve as reservoirs for a wide range of pathogens including viruses, bacteria, fungi, protozoa, and nematodes, contributing to the transmission of diseases such as Crimean-Congo hemorrhagic fever, tick-borne encephalitis, and African swine fever among others. The interface between wildlife, livestock, and humans facilitates the transmission of zoonotic pathogens, exacerbated by nomadic and pastoralist lifestyles that promote interactions between wildlife and domestic animals. This movement of animals across landscapes enhances the dispersion of tick vectors, increasing the risk of pathogen exposure for diverse populations. Historically, tick identification in sub-Saharan Africa has relied on morphological characteristics despite limitations such as species overlap and variability. Molecular techniques offer a more precise means of species identification, providing critical data for effective tick and pathogen management strategies. Integrating molecular approaches into tick research enhances our understanding of tick diversity, distribution patterns, and pathogen dynamics. This knowledge is essential for developing targeted interventions to mitigate the impact of tick-borne diseases on public and veterinary health worldwide.</p>","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"1-13"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}