{"title":"Vancomycin powder as a preventive measure for wound infection in total hip arthroplasty: a prospective cohort study.","authors":"Iskander Mahdi Alardi","doi":"10.36740/WLek/197300","DOIUrl":"https://doi.org/10.36740/WLek/197300","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To compare the results of use of vancomycin powder in the prevention of wound infection in operations of hip replacement that is total to a control group.</p><p><strong>Patients and methods: </strong>Materials and Methods: 40 patients undergoing total hips arthroplasty during period (January 2021 to January 2022). Patients were allocated in a random way into two categories so that one group received vancomycin powder and served a study group; the other group received no such intervention and served as a control group. Patients underwent steps: after completion of surgery, regular closure in layers was done; drain was inserted into sub-muscular layers while vancomycin powder (1 gm) was put in subcutaneous layer before skin closure; drain was closed for two hours and then reopened.</p><p><strong>Results: </strong>Results: Superficial infection was seen in 1 (5.0%) and 2 (10.0%), in vancomycin category & group of control and variation was insignificant statistically (p=1.0). Deep infection was seen in 0 (0.0%) and 3 (15.0%), in vancomycin category and group of control, and variation was insignificant statistically (p=0.231). Wound complication was seen in 2 (10.0%) and 0 (0.0%), in vancomycin group and group of control, respectively and variation was insignificant statistically (p=0.487). Return to operating room was seen in 1 (5.0%) and 1 (5.0%), in vancomycin category and category of control, respectively and variation was insignificant statistically (p=1.0). Peri-prosthetic fracture was not reported.</p><p><strong>Conclusion: </strong>Conclusions: Utilization of powder of vancomycin is safe and efficient way in preventing deep wound infection accompanying total hip arthroplasty but small sample size herein suggested need for further future studies to validate our results.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 2","pages":"342-346"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haider Shahaeed Mohammed, Abdul-Hassan Mahdi Salih, Ali Abid Saadoon
{"title":"Vitamin D status as a laboratory marker of whole spectrum of severity of osteoarthritis of knee.","authors":"Haider Shahaeed Mohammed, Abdul-Hassan Mahdi Salih, Ali Abid Saadoon","doi":"10.36740/WLek/201201","DOIUrl":"https://doi.org/10.36740/WLek/201201","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The aim of our research is to examine any relationship between vitamin D status and knee osteoarthritis.</p><p><strong>Patients and methods: </strong>Materials and Methods: A specimen of 160 individuals presented to medical services in outpatient doctor's office were recruited into evaluations 80 participants with established diagnosis of osteoarthritis of knee chosen as cases and 80 participants without clinical and radiological evidence of knee joint osteoarthritis chosen as controls, both were assessed by meticulous clinical and rheumatologic examination, radiological assessment, and vitamin D quantification. Diagnosis of cases was verified in accordance with American college of rheumatology criteria, for whom both pain and radiological severity were measured.</p><p><strong>Results: </strong>Results: mean age is 69.2570, 96 females, 64 males. F: M ratio is 1.5:1, 85 had subnormal vitamin D while 75 had normal vitamin D level. Majority who were vitamin D insufficient belong to cases 83.5%. Majority of those who have adequate vitamin D level related to control group with significant association P-value 0.0001. Most of cases who were vitamin D insufficient 60 out of 71 have grade 3 and 4 kellegren-Lawrence score of radiological severity with significant association where p-value 0.001, 14 out of 71 and 50 out of 71 case who have vitamin D inadequacy suffering from moderate and severe pain by visual analogue scale subsequently with significant association P value 0.001.</p><p><strong>Conclusion: </strong>Conclusions: vitamin D status had substantial relation with various aspects of severity and perhaps worsening of knee osteoarthritis, emphasizing necessity of promoting the vitamin D quantification in those patients.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 2","pages":"273-280"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rana Murtadha Hasan, Ameena Ryhan Diajil, Noor Mohammed Ali, Fawaz Aswad, Lina Ziyad Tariq
{"title":"Clinical characteristics of temporomandibular disorders in a sample of Iraqi patients.","authors":"Rana Murtadha Hasan, Ameena Ryhan Diajil, Noor Mohammed Ali, Fawaz Aswad, Lina Ziyad Tariq","doi":"10.36740/WLek/197186","DOIUrl":"10.36740/WLek/197186","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To evaluate the symptoms and indicators that people with TMD experience and encourage them to seek treatment at an academic oral medicine clinic.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study includes temporomandibular joint patients who visited the oral medicine clinic at the University of Baghdad's College of Dentistry between October 2021 and May 2022. The information was gathered from temporomandibular joint patients' medical records.</p><p><strong>Results: </strong>Results: In the research herein, 323 patients in total were included, females 234(72.4%) and 89(27.6%) males, the patient's mean age was (31.38 ± 14.085), and there was no discernible gender difference in mean age. In this study, the most prevalent temporomandibular joint signs and symptoms were temporomandibular joint clicking 73.6% with no significant difference between females and males. In comparison, dislocation is the least prevalent and the most prevalent muscle spasm was the masseter muscle with a percentage of 50.4%) while the sternocleidomastoid muscle is the least one.</p><p><strong>Conclusion: </strong>Conclusions: The research results demonstrated a significant prevalence of temporomandibular joint disorder and the necessity of preventing it to improve the overall well-being of people in general.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 1","pages":"143-147"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tetiana O Timokhina, Olena V Anoprienko, Natalia I Gryg, Andrii A Boiko, Ihor M Kolodka
{"title":"Psychological and social aspects of the life of patients with periodontal and maxillofacial diseases.","authors":"Tetiana O Timokhina, Olena V Anoprienko, Natalia I Gryg, Andrii A Boiko, Ihor M Kolodka","doi":"10.36740/WLek/197121","DOIUrl":"10.36740/WLek/197121","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To analyze the impact of concurrent periodontal and maxillofacial diseases on the mental state and quality of life of patients aged 18-60 years for future comprehensive rehabilitation.</p><p><strong>Patients and methods: </strong>Materials and Methods: A total of 61 patients (aged 28-60 years) with periodontal diseases and concomitant maxillofacial disorders were studied. All patients had a dental examination, accompanied by assessments of anxiety, depression, and self-esteem with the Hospital Anxiety and Depression Scale (HADS), the Dembo-Rubinstein self-assessment method, and the Chaban Quality of Life Scale (CQLS).</p><p><strong>Results: </strong>Results: The analysis of the HADS A score revealed that 31.1% of patients had a clinical level of anxiety, whereas 41% of patients had a subclinical level of anxiety. Based on the HADS D score, 21.3% of patients had a clinical level of depression, whereas 50.8% had a subclinical level of depression. The aspects of appearance, health, and confidence are highly correlated with patients' mental well-being. The quality of life assessment indicates that the majority of patients with concurrent periodontal and maxillofacial diseases experience a low or moderate quality of life.</p><p><strong>Conclusion: </strong>Conclusions: Patients with periodontal and maxillofacial diseases require not only dental care but also comprehensive rehabilitation, since appearance and physical health have a major impact on their quality of life.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 1","pages":"28-34"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bohdan A Kotelyukh, Oleksandr Movchan, Serhii Teslia, Dmitro Shtonda
{"title":"Prospects of osteosynthesis with fixators based on magnesium alloys, mechanical and physiological properties. The state of the problem at the current stage.","authors":"Bohdan A Kotelyukh, Oleksandr Movchan, Serhii Teslia, Dmitro Shtonda","doi":"10.36740/WLek/197141","DOIUrl":"10.36740/WLek/197141","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The aim of this work is to analyze the available scientific information regarding to the prospects of metal-osteosynthesis with biodegradable fixators based on magnesium alloys.</p><p><strong>Patients and methods: </strong>Materials and Methods: A set of general and special methods of scientific knowledge are used in the article. Search and analysis of full-text articles and scientific publications - carried out in databases of systematic reviews of MEDLINE, PubMed, Web of Science, Google Scholar, Scopus.</p><p><strong>Conclusion: </strong>Conclusions: Magnesium-based implants contribute to a tissue regeneration and healing during degradation and do not require removal. This allows you to avoid the second surgical intervention and reduces treatment costs. That is why the development and implementation of biodegradable fixators for osteosynthesis is of great importance.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 1","pages":"162-167"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rasha Farhood Medlool, Karar Nadhum Obaid Aljabry, Majid Kadhum Hussain
{"title":"The impact of estrogen receptor β gene polymorphisms on the atherogenic index and coronary artery disease in Iraqi population.","authors":"Rasha Farhood Medlool, Karar Nadhum Obaid Aljabry, Majid Kadhum Hussain","doi":"10.36740/WLek/199561","DOIUrl":"10.36740/WLek/199561","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To study the impact of the estrogen receptor beta polymorphisms rs4986938 (AluI) and rs1256049 (RsaI) on ischemic heart disease as well as the atherogenic index in Iraqi population.</p><p><strong>Patients and methods: </strong>Materials and Methods: A case-control research study was conducted on a sample of Coronary artery disease patients in addition to a group of normal individuals. Serum lipid concentrations were measured in the participants, and the ER gene (rs1256049, rs4986938) was genotyped by PCR- RFLP.</p><p><strong>Results: </strong>Results: Atherogenic serum lipid concentrations increased significantly in Coronary artery disease patients relative to the control group. Genotyping of the estrogen receptor β gene forrs4986938 SNP revealed a significant (OR=2.79, P=0.000) elevation of the GA genotype carriers in Coronary artery disease versus the control groups. The genotype analysis of thers1256049 SNP failed to exhibit a significant variation. Atherogenic index and serum lipid concentration markedly elevated with these polymorphisms.</p><p><strong>Conclusion: </strong>Conclusions: The polymorphisms of ESRβ rs4986938, (not for rs1256049) was associated with risk of Coronary artery disease and implicated in changes of serum lipid concentrations and atherogenic index in Iraqi population. Additional studies of ESRβ genetic variation and risk of CVD are warranted.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 1","pages":"148-155"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hameeda Hadi Abdulwahid, Abeer Hussein, Mazin Hamid Oda
{"title":"The pharmacogenomic biomarkers and clinical effect of FSHR gene variants on female infertility.","authors":"Hameeda Hadi Abdulwahid, Abeer Hussein, Mazin Hamid Oda","doi":"10.36740/WLek/200331","DOIUrl":"10.36740/WLek/200331","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The aims of this study are to detect the genetic polymorphisms of FSHR rs6166 (C> T) and rs6165 (C> T) gene particularly that associated with the response to FSH treatment and their effects on the pathogenesis of infertility in Iraqi women.</p><p><strong>Patients and methods: </strong>Materials and Methods: 210 Iraqi women, aged 20 to 34, who had just been diagnosed with infertility were included in this prospective case control research, whereas the control group consisted of 50 clinically healthy women who were free of any disorders. Following the guidelines for inclusion and exclusion in the study, each of the participating women saw a gynecologist to confirm. The time frame for this From November 2021 to June 2022, the investigation was carried out.</p><p><strong>Results: </strong>Results: The findings of this study in infertile women, clearly indicates that multiple genotypes of FSHR gene particularly (rs6166) (C>T) and (rs6165) (C>T), that include the homozygous wild genotype (CC), homozygous mutant (TT) and heterozygous (CT) genotype. The T allele was significantly increased (P<0.05) in poor responder infertile women for both rs6166 and rs6165 in FSHR which associated significantly with poor response to FSH in Iraqi infertile women.</p><p><strong>Conclusion: </strong>Conclusions: Polymorphisms in FSHR gene may be associated with decrease in response to FSH treatment and it was associated with pathogenesis of infertility in Iraqi women/ Kerbala province.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 1","pages":"90-99"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olha I Okhrimenko, Mariia M Rohovenko, Olena Yu Pop, Alla V Marchuk, Iryna Ya Hrynyk, Larisa L Stakhova, Svitlana I Bilozerska
{"title":"Coping behavior of students as a means of overcoming stressful situations under martial law.","authors":"Olha I Okhrimenko, Mariia M Rohovenko, Olena Yu Pop, Alla V Marchuk, Iryna Ya Hrynyk, Larisa L Stakhova, Svitlana I Bilozerska","doi":"10.36740/WLek/201320","DOIUrl":"https://doi.org/10.36740/WLek/201320","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The aim is to study the peculiarities of students' coping behavior in stressful situations under martial law.</p><p><strong>Patients and methods: </strong>Materials and Methods: During the 2023-2024 academic year, the research was conducted based among 3rd-year students (n = 82) aged 20-22 years, including women (n = 42) and men (n = 40). Research methods: bibliosemantic, diagnostic, system analysis and generalization, statistical. The diagnostic work involved using the following methods: \"Coping Inventory for Stressful Situations\" and \"Strategic Approach to Coping Scale.\"</p><p><strong>Results: </strong>Results: It has been found that the problem of students being in a stressful situation of war is directly related to their coping behavior. It has been found that female students' indicators of emotion-oriented coping strategies are more pronounced than those of male students (p 0.05) high level of expression of the following models of behavior to overcome stressful phenomena: search for social support (women - 57.1 %; men - 55.0 %), social contact (women - 54.8 %; men - 52.5 %), precautionary actions (women - 52.4 %; men - 50.0 %).</p><p><strong>Conclusion: </strong>Conclusions: The effectiveness of any coping strategy depends on the current situation in students' lives and their existing personal resources. In stressful situations, students' coping behavior is effective, and the following coping strategies are rational: emotion-oriented, search for social support, and problem-oriented. This confirms students' productive personal standpoint, allowing them to adapt to any stressful situation under martial law.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 2","pages":"281-287"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mykola I Kravtsiv, Maxym O Dudchenko, Dmytro M Ivashchenko, Mykola P Shevchuk, Oleh H Krasnov, Tamara V Horodova-Andrieieva, Olexandr M Liulka
{"title":"Role of diagnostic laparoscopy in abdominal disorders with uncertain diagnosis: a rare case report.","authors":"Mykola I Kravtsiv, Maxym O Dudchenko, Dmytro M Ivashchenko, Mykola P Shevchuk, Oleh H Krasnov, Tamara V Horodova-Andrieieva, Olexandr M Liulka","doi":"10.36740/WLek/200416","DOIUrl":"https://doi.org/10.36740/WLek/200416","url":null,"abstract":"<p><p>Female patient was hospitalized in the surgical of the Municipal Enterprise \"2nd City Clinical Hospital of Poltava City Council\" (Poltava, Ukraine) in 2023. The patient underwent a complete general clinical examination, a plain radiograph of the abdominal cavity, fibrogastroduodenoscopy, colonoscopy, ultrasound of the abdominal organs, CT scan of the abdominal organs. Diagnostic laparoscopy was performed to make a final diagnosis. A plain radiography of the abdominal cavity revealed no pathology. Ultrasound of the abdominal organs revealed a pelvic mass. A computed tomography scan revealed damage to the pelvic organs in the form of a neoplasm and an enlargement of the left ovary. The preliminary diagnosis was a pelvic tumor, tumor of the left ovary. Diagnostic laparoscopy was performed to make the diagnosis. A rounded formation was defined in Douglas space. The capsule of the formation was opened and pus was released. The abscess wall was opened, and a foreign body (gauze pad) was removed from the cavity. The patient was discharged from the hospital in satisfactory condition on the fifth day after surgery. The case we examined emphasizes that when assessing the nature of an intra-abdominal neoplasm, it is necessary to remember about foreign bodies, especially in patients after surgical interventions. Diagnostic laparoscopy is a technically advanced and minimally invasive procedure for the diagnosis and treatment of intra-abdominal gossypiboma.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 2","pages":"479-486"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alaa Abd Al-Hussain Naem, Mona N Al-Terehi, Fadhaa Abdulameer Ghafil, Sahar Majeed, Najah Rayish Hadi, Defaf Al-Mudafer
{"title":"Influence of different factors (duration of disease, gender, education, patients' history, job and age) in metformin response in type 2 diabetes mellitus patient.","authors":"Alaa Abd Al-Hussain Naem, Mona N Al-Terehi, Fadhaa Abdulameer Ghafil, Sahar Majeed, Najah Rayish Hadi, Defaf Al-Mudafer","doi":"10.36740/WLek202407108","DOIUrl":"10.36740/WLek202407108","url":null,"abstract":"<p><strong>Objective: </strong>Aim: This study aims to evaluate how various factors affect various aspects of glycemic control in individuals with type 2 diabetes who are undergoing metformin treatment.</p><p><strong>Patients and methods: </strong>Materials and Methods: A cross-sectional study involved 150 participants who met specific criteria, including being aged between 30 and 70, having a type 2 diabetes diagnosis, and using 1000 mg of metformin as the monotherapy for at least three months. Collected data encompassed various measures, such as levels of glycated hemoglobin (HbA1c), fasting blood glucose concentrations, fasting serum insulin levels, Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), and insulin sensitivity.</p><p><strong>Results: </strong>Results: Our research reveals that when it comes to factors such as several socio-demographic variables, there is no statistically significant difference (p-value ≥ 0.05) between patients who exhibit a positive response to metformin and those who do not. Nevertheless, distinctions were noted in patients' previous history and the duration of their illness, which did influence their treatment response.</p><p><strong>Conclusion: </strong>Conclusions: Glycemic parameters in individuals with type 2 diabetes can be impacted by a range of factors, such as age, gender, and occupation also it's important to note that these outcomes influenced by additional variables like the adherence for medication, and the existence of diabetes-related complications.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"77 7","pages":"1356-1363"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142143397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}