Wiadomosci lekarskie最新文献

{"title":"The clinical and pathogenetic manifestations of gastroesophageal reflux disease and obesity and approaches to their diagnosis, treatment, and prevention: current state of the problem (literature review).","authors":"Taras I Griadil, Bohdana V Bezushko, Oleksandr O Dutko, Mykhailo M Lopit","doi":"10.36740/WLek/203909","DOIUrl":"https://doi.org/10.36740/WLek/203909","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The purpose of this study is to review the literature to determine the common pathogenetic mechanisms (PM) between gastroesophageal reflux disease (GERD) and obesity, as well as to analyze the impact of one disease on the other, followed by a review of the basic principles of diagnosis and treatment of patients with a combination of these comorbidities.</p><p><strong>Patients and methods: </strong>Materials and Methods: The literature review included an analysis of articles from the Scopus and Web of Science databases, with a focus on pathogenesis, clinical data, diagnosis and treatment of GERD and obesity. The following keywords were used to find relevant materials on the research topic: \"GERD\", \"obesity\", \"pathogenesis\", \"treatment\", \"clinical trials\".</p><p><strong>Conclusion: </strong>Conclusions: A series of studies have shown that there are risk factors that increase the development of GERD: stress, bad habits, excessive body mass index (BMI), advanced age and lifestyle. At the same time, obesity has similar risk factors to GERD, which in turn prompts the search for correction of common PM, new ways of diagnosis and comprehensive personalized treatment.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 4","pages":"937-942"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practical experience in the surgical treatment of newborns with isolated gastrointestinal perforations based on scientific evidence.","authors":"Olga M Gorbatyuk, Taras V Martyniuk, Andrey A Momotov","doi":"10.36740/WLek/203901","DOIUrl":"https://doi.org/10.36740/WLek/203901","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To share first-hand experience in the surgical treatment of newborns with isolated gastrointestinal perforations.</p><p><strong>Patients and methods: </strong>Materials and Methods: This study examines 71 newborns with perforated peritonitis: 53 (74.65%) had necrotizing enterocolitis, 14 (19.72%) had isolated gastrointestinal perforations, and 4 (5.63%) had other intestinal perforations. Diagnosis involved clinical, laboratory, radiographic, ultrasound, and histological examinations of surgical and autopsy samples.</p><p><strong>Results: </strong>Results: The most significant risk factors for isolated perforations of the gastrointestinal tract in newborns were acute birth asphyxia and pathology of the respiratory system, which required tracheal intubation in 100% of children. Isolated perforations were localized in the stomach (n=6), jejunum (n=3), ileum (n=2), duodenum (n=1), colon (n=2). Morphological features of isolated perforations are as follows: a rapid muscle layer wasting of the wall, sometimes with the absence of muscle fragments; vascular malformations in the submucosal layer of the wall; ulcerous defect without necrotic changes; absence of pneumatosis of the intestinal wall. In isolated perforations, the operation of choice was closure of perforation in 11 children. In 2 patients direct interintestinal anastomoses were performed. Case mortality rate was 21.43% (3 newborns died).</p><p><strong>Conclusion: </strong>Conclusions: 1. Clinical and pathomorphological features of gastrointestinal perforations in newborns indicate that isolated perforations are a separate nosological entity. 2. Isolated perforations of the gastrointestinal tract in newborns are characterized by such clinical differences as distress syndrome, prematurity, early onset, local lesions of a hollow organ, moderate peritonitis, favorable course and prognosis. 3. Isolated perforations are secondary to fibromuscular dysplasia of the wall of a hollow organ, indicating congenital pathology. 4. The operation of choice for isolated perforations is the excision of the edges of the perforation and closure of the perforation. 5. The prognosis for the gastrointestinal isolated perforations is favorable. Mortality was 21,43%.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 4","pages":"894-899"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic challenges of Lisfranc joint injuries: A review of imaging methods.","authors":"Konrad Talarek, Michał Świta, Julia Szewczyk, Anna Szuciak, Karolina Turżańska","doi":"10.36740/WLek/202333","DOIUrl":"https://doi.org/10.36740/WLek/202333","url":null,"abstract":"<p><p>Lisfranc injuries, which affect the tarsometatarsal joint and are relatively rare, have a 20% misdiagnosis rate. This can result in serious complications such as foot instability, degeneration, or chronic pain. Due to the absence of clear diagnostic guidelines, this article reviews existing literature and research to propose an algorithm for identifying potential Lisfranc injuries. The literature review summarizes information on diagnostic methods for Lisfranc complex injuries. It was executed using PubMed, Web of Science, and Google Scholar databases. Scientific publications published between 2016 and 2024 were counted in review and scientific before this period. Lisfranc complex injuries, especially subtle cases, are frequently missed due to both patient oversight and physician error. In diagnostic trials, tools like traditional X-rays or CT scans are commonly employed, however MRIs and ultrasounds are often overlooked. Weight-bearing X-rays and weight-bearing CT could be promising due to their high sensitivity. Appropriate patient interview and physical examination along with imaging are essential points for making an accurate diagnosis. It is important to diagnose Lisfranc injuries to prevent the development of serious complications. Greater patient awareness and a comprehensive diagnostic approach by doctors are key to improving detection rates. Subtle Lisfranc injuries are the greatest diagnostic challenge. Weight-bearing CT scans and radiographs could be very helpful in identifying these injuries. Further research is needed to optimize the use of these imaging methods.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 3","pages":"626-633"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression in older adults.","authors":"Kamila Kwiatkowska, Nataliia Fedorenko, Silvija Ille, Artur Jakubiak","doi":"10.36740/WLek/202719","DOIUrl":"https://doi.org/10.36740/WLek/202719","url":null,"abstract":"<p><p>Depression is an increasingly common disease in elderly. It affects almost every sphere of senior life and is a socio-medical challenge for the modern world. Unfortunately, it is rarely diagnosed in this age group, which concerns the use of pharmacological and therapeutic intervention. The complex etiology and comorbidity of somatic diseases makes diagnosis difficult because depressive symptoms are attributed to the underlying disease. Often, the lack of treatment and ignoring the symptoms by the patient and their relatives can contribute to suicide behavior of seniors. The phenomenon of population aging is observed all over the world. The average lifespan of people is increasing, which means an increase in the number of people in senior age. Depression affects more and more elderly people. Lack of interest from family and society, illnesses, loneliness, isolation make seniors experience depressive disorders more often. It is worth taking a closer look at the problem of depression among the elderly and implementing appropriate actions to minimize the problem. The key role is played by educating society about the characteristic symptoms of depression in old age and preventing its occurrence, among others by activating the elderly.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 3","pages":"639-642"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Educational program to asses and promote knowledge of Al-Zahraa hospital nurses about trichomoniasis disease, Al-Najaf city.","authors":"Wijdan Dhaidan Shnain Al-Abbas, Rehab Lafta Mohammad, Kawther Alqaseer, Ohood Aqeed Radhi","doi":"10.36740/WLek/201339","DOIUrl":"10.36740/WLek/201339","url":null,"abstract":"<p><strong>Objective: </strong>Aim: This study included implementing an educational program to evaluate and promote nurses' knowledge of trichomoniasis disease which caused by Trichomonas vaginalis parasite.</p><p><strong>Patients and methods: </strong>Materials and Methods: 100 randomly samples of nurses working in different units in Al-Zahraa Hospital - Najaf City, Iraq. This semi-experimental study was performed. The study was conducted from December 2023 until April 2024. It included a sample of different ages, gender and experience, working in different units in the hospital, married and unmarried, as well as those living in urban and rural areas.</p><p><strong>Results: </strong>Results: The results show the total rating of sample knowledge concerning Trichomoniasis in primary test was a moderate with a mean (0.57) and the mean of next test was a good (0.84), also the results observed a highly significant difference (P <0.01) between pre-test and post-test assessments. In addition, according to their Socio-Demographic Characteristics, the study showed no significant difference in the knowledge scores in the next test.</p><p><strong>Conclusion: </strong>Conclusion: This study concluded that there was an improvement in knowledge after the program for all nurses.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 2","pages":"316-327"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical manifestation, laboratory and instrumental characteristics of infants born to mothers with a complicated anamnesis.","authors":"Olesya M Horlenko, Yuriy Yu Chuhran, Gabriella B Kossey, Viktoria V Ivano, Mariya A Derbak, Volodymyr D Symulyk, Lybov Yu Pushkash","doi":"10.36740/WLek/203889","DOIUrl":"10.36740/WLek/203889","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To improve early diagnosis by analyzing the pathological pattern of ≪mother-newborn≫ in newborns.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study group included newborns with a diagnosis of \"Infection specific to the perinatal period, unspecified\" (P39,9, n=64), born to mothers (age 31,31 ± 2,08 years) with a complicated diagnosis and a control group (n=31) of infants.</p><p><strong>Results: </strong>Results: Clinical manifestations in newborns mainly included involvement of the central nervous system (57,8%), cardiovascular system (12,0%), congenital heart defects (2,8%), jaundice (11,0%), hepatosplenomegaly (5,2%), exanthema (9,0%), hypothermia (70,6%). Markers of inflammatory response confirmed an increase in the level of IL-1, a significant increase in IL-6 levels, the level of IL-8 in the studied contingent also significantly differs from the data of the control group, the level γ-IFN also exceeded the reference values by 2,4 times. Hypoxic-ischemic encephalopathy was detected in 63 infants (57,8%) and intracranial hemorrhage was diagnosed in 25 (22,9%) infants.</p><p><strong>Conclusion: </strong>Conclusions: The values of cytokine profile parameters (IL-1, IL-6, IL-8, IL-10) on the first day of life varied within the reference values, but with significant differences from the values of the control group, which were 9,24; 20; 11 times, respectively. The levels of inflammatory mediators (γ-IFN, procalcitonin, neopterin, TNF-α, Pg E2) significantly differed from the data of the control group and exceeded the upper limit of reference values by 2,4; 40; 8,9; 25; 3,5 times, respectively.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 4","pages":"783-789"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Method of conservative treatment of chronic venous insufficiency and post-thrombophlebitic syndrome of the lower extremities.","authors":"Anatolii B Zubakha, Serhii V Malyk, Iryna O Chorna, Oleksii V Storozhenko, Mykola I Kravtsiv, Tetiana A Skotarenko, Roman A Yaroshenko","doi":"10.36740/WLek/205363","DOIUrl":"https://doi.org/10.36740/WLek/205363","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To develop of a new complex of conservative techniques that eliminate clinical manifestations of chronic venous insufficiency, preserve the ability to work and improve the quality of life of patients, being the main method of preoperative preparation and postoperative rehabilitation in some patients.</p><p><strong>Patients and methods: </strong>Materials and Methods: The article describes clinical and practical recommendations for the diagnosis and treatment of patients with chronic venous insufficiency (CVI) and post-thrombophlebitic syndrome (PTS) of the lower extremities. The treatment of these pathologies should take into account the variability and combination of symptoms, comorbidities, as well as the patient's work activity and socioeconomic factors that may affect the modification of classical treatment regimens.</p><p><strong>Results: </strong>Results: The examination and treatment of patients with this pathology has been carried out at the surgical department of the Poltava Central District Clinical Hospital since 2019 year. On the basis of a complex ultrasound examination with the determination of reflux in the deep and superficial veins of the lower extremities and horizontal reflux in the perforating veins, patients were divided into two groups. The first group consisted of 28 (57.1%) patients with superficial and the second group of 16 (42.9%) patients with deep venous hypertension.</p><p><strong>Conclusion: </strong>Conclusions: The main component of the conservative treatment of this pathology (CVI and PTS) is compression therapy, venotonics, medicines that improve microcirculation in the affected tissues, laser therapy, salves and gels were used locally, depending on the phase of the wound process, in case of trophic changes.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 5","pages":"1032-1036"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in cervical cancer epidemiology and vaccination coverage in Ukraine.","authors":"Viktor V Semenov, Lilia V Kriachkova, Adriana E Boată, Marius M Geantă","doi":"10.36740/WLek/205358","DOIUrl":"https://doi.org/10.36740/WLek/205358","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To evaluate regional aspects of cervical cancer epidemiology and adherence to vaccination in Ukraine.</p><p><strong>Patients and methods: </strong>Materials and Methods: The data about cervical cancer age-standardised incidence rate in 2014-2019 in Ukraine was obtained from the archives of National Cancer Registry of Ukraine. The data about vaccination coverage were obtained from the reports by the Centre of Public Health of Ukraine.</p><p><strong>Results: </strong>Results: The average cervical cancer age-standardised incidence rate in Ukraine in 2014-2019 was 14.9 per 100,000. Zhytomyr, Khmelnytskyi and Kirovohrad oblasts exhibited values 20% above the national level. The general trend of cervical cancer incidence at the national level in 2014-2019 was declining (from 15.0 to 14.1). Kyiv, Mykolaiv, Sumy and Chernihiv oblasts exhibited increasing trends in age-standardised incidence rate (>20%). The average zero-dose children proportion in Ukraine in 2016 -2024 was 30.3%. Vaccination coverage in Ukraine has been improving over the observation period in all oblasts.</p><p><strong>Conclusion: </strong>Conclusions: Ukraine in 2014-2019 was characterised by the decreasing cervical cancer age-standardised incidence rate. Vaccination coverage in Ukraine in 2016-2024 has been improving, which increases the likelihood of a good response to the planned HPV vaccination campaign. Several regions with deviations from the national levels of cervical cancer incidence and vaccination coverage were identified.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 5","pages":"999-1005"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of education and labour integration of master's graduates in public health: an insider's perspective.","authors":"Tetiana S Gruzieva, Nataliia V Hrechyshkina, Yurii B Yashchenko, Hanna V Inshakova","doi":"10.36740/WLek/205374","DOIUrl":"https://doi.org/10.36740/WLek/205374","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To determine the opinions of master's graduates in Public Health regarding the quality of the educational process and its impact on employment and further professional activities.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study utilized bibliosemantic, sociological, medical-statistical methods, and content analysis. The research materials included scientific publications, national-level regulatory legal acts, WHO programme documents, and sociological research questionnaires. The programme involved sociological surveys of graduates of the Master's Programme in Public Health. Statistical processing of sociological survey results was carried out by calculating the standard error and confidence interval.</p><p><strong>Results: </strong>Results: Anonymous surveys revealed that 94.1% of the 2024 graduates of the Master's Programme in Public Health at Bogomolets National Medical University were employed. Their assessment of the quality of educational services was high (82.4%) and fairly high (17.6%), which was ensured by obtaining in-depth theoretical knowledge (93.8%), acquiring essential practical skills (93.8%), and developing the necessary competencies (100%). High learning outcomes were achieved due to the quality of the educational programme content (98.3%), the possibility of forming an individual learning trajectory, modern teaching methods (88.2%), the high qualification of teaching staff (100%), practical orientation (94.1%), integration of education and research (94.1%), adherence to academic integrity (94.1%), an adequate educational environment (82.4%), and comprehensive student support (94.1%-100%). The feedback from master's graduates serves as an essential foundation for improving the training process for public health professionals.</p><p><strong>Conclusion: </strong>Conclusions: Master's graduates in Public Health highly evaluate the quality of the educational programme and the overall educational process, emphasising their positive and decisive impact on employment. The obtained data allow for a comprehensive assessment of learning outcomes, the dissemination of best practices, and the resolution of problematic issues. Additionally, they help determine ways to improve the Master's Programme in Public Health and the educational process in general to ensure the competitiveness of graduates.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 5","pages":"1078-1083"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teaching clinical communication skills in Ukraine: a cross-sectional study.","authors":"Iurii L Kuchyn, Kateryna Yu Bielka, Olena I Kefeli-Ianovska, Ganna S Trepet, Lesya V Lymar","doi":"10.36740/WLek/205694","DOIUrl":"https://doi.org/10.36740/WLek/205694","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To analyze the Ukrainian medical graduates' self-assessment of communicative competence, review the Ukrainian medical education related to teaching clinical communication, and to suggest ways of improving fostering clinical communication skills.</p><p><strong>Patients and methods: </strong>Materials and Methods: A descriptive literature review was done. The authors held a cross-sectional study using a convenience sample study in 2024 with the Bogomolets NMU 190 medical PhD students and practicing physicians, who were questioned to evaluate their clinical communication skills. The participants were offered a 12-item questionnaire regarding the clinical communicative competence, with open- and close-ended questions. The survey results were processed using statistical methods of grouping, generalization (in absolute and relative terms), and comparison. For relative values, standard errors and confidence intervals (95%) were calculated. The probability of difference between observation groups was determined using chi-square test (χ2). Open-ended questions were analyzed using the qualitative description method.</p><p><strong>Results: </strong>Results: Among eligible 700 individuals, 190 individuals participated in the study, including 120 medical PhD students and 70 practicing physicians. Total majority could not recollect being taught medical communication during their undergraduate studies. Only 16% have heard about the SPIKES protocol. The analysis of the open-ended questions revealed answer clusters, in which the respondents associated clinical communicative competence with language skills, emotional self-control and polite behavior. This could be caused by learning the communication course at the Language or Psychology Departments.</p><p><strong>Conclusion: </strong>Conclusions: Clinical communication skills are underestimated in the medical curriculum, taught by non-clinical departments. The Ukrainian education needs integration of the clinical communication course into practice course, to be taught by practicing physicians, which, in its turn, requires training Ukrainian clinical teachers by European communication protocols.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 5","pages":"1052-1057"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}