{"title":"一名乌克兰武装部队士兵在装填弹药时发生十二指肠球囊溃疡。","authors":"Anatoly A Avramenko, Anna K Magdenko","doi":"10.36740/WLek/208989","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Aim: Conduct an analysis and provide a pathophysiological justification for the case of the formation of an ulcer of the duodenal bulb in a 27-year-old soldier of the Armed Forces of Ukraine.</p><p><strong>Patients and methods: </strong>Materials and Methods: After collecting the anamnesis, the patient underwent a comprehensive examination, which included step-by-step pH-metry, esophagogastroduodenoscopy, testing for Helicobacter pylori infection (HP) (urease test and microscopic examination of stained smears-prints) in 4 topographic zones of the stomach, and histological examination of the gastric mucosa in the same zones.</p><p><strong>Results: </strong>Results: When collecting a family history, it was found that relatives on one male line - father and grandfather - suffered from ulcer disease. It was established that on the eve of an exacerbation, which lasted 3 weeks, the soldier helped load a car, repeatedly lifting boxes with ammunition up to 20 kg to a height of 1.5 m. During pH-metry it was found that the acidity level of gastric juice corresponded to the basal normacidity of total. During esophagogastroduodenoscopy the following diagnosis was made: \"Ulcer of the duodenal bulb in the active stage (in the middle third, along the back wall, 1.5 x 0.8 cm, the ulcer defect is covered with gray fibrin). Erythematous duodenogastropathy. Indirect signs of pancreatopathy.\" The presence of chronic gastritis in the active stage in the patient was confirmed by the results of histological examination of the gastric mucosa. The type of gastritis (non-atrophic) was confirmed by testing for HP infection, which revealed a high concentration of the active form of bacteria - (+++) in all 4 topographic zones of the stomach.</p><p><strong>Conclusion: </strong>Conclusions: Stress associated with participation in military operations led to the active reproduction of Helicobacter pylori infection and, accordingly, an increase in \"residual\" ammonia in the stomach cavity. Heavy physical exertion, which was accompanied by a sharp contraction of the muscles of the anterior abdominal wall, created a \"bellows\" effect, which concentrated the \"residual\" ammonia in the cavity of the duodenal bulb and led to the formation of an ulcer.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"78 7","pages":"1298-1301"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A case of duodenal bulb ulcer formation in a soldier of the ukrainian armed forces during ammunition loading.\",\"authors\":\"Anatoly A Avramenko, Anna K Magdenko\",\"doi\":\"10.36740/WLek/208989\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Aim: Conduct an analysis and provide a pathophysiological justification for the case of the formation of an ulcer of the duodenal bulb in a 27-year-old soldier of the Armed Forces of Ukraine.</p><p><strong>Patients and methods: </strong>Materials and Methods: After collecting the anamnesis, the patient underwent a comprehensive examination, which included step-by-step pH-metry, esophagogastroduodenoscopy, testing for Helicobacter pylori infection (HP) (urease test and microscopic examination of stained smears-prints) in 4 topographic zones of the stomach, and histological examination of the gastric mucosa in the same zones.</p><p><strong>Results: </strong>Results: When collecting a family history, it was found that relatives on one male line - father and grandfather - suffered from ulcer disease. It was established that on the eve of an exacerbation, which lasted 3 weeks, the soldier helped load a car, repeatedly lifting boxes with ammunition up to 20 kg to a height of 1.5 m. During pH-metry it was found that the acidity level of gastric juice corresponded to the basal normacidity of total. During esophagogastroduodenoscopy the following diagnosis was made: \\\"Ulcer of the duodenal bulb in the active stage (in the middle third, along the back wall, 1.5 x 0.8 cm, the ulcer defect is covered with gray fibrin). Erythematous duodenogastropathy. Indirect signs of pancreatopathy.\\\" The presence of chronic gastritis in the active stage in the patient was confirmed by the results of histological examination of the gastric mucosa. The type of gastritis (non-atrophic) was confirmed by testing for HP infection, which revealed a high concentration of the active form of bacteria - (+++) in all 4 topographic zones of the stomach.</p><p><strong>Conclusion: </strong>Conclusions: Stress associated with participation in military operations led to the active reproduction of Helicobacter pylori infection and, accordingly, an increase in \\\"residual\\\" ammonia in the stomach cavity. Heavy physical exertion, which was accompanied by a sharp contraction of the muscles of the anterior abdominal wall, created a \\\"bellows\\\" effect, which concentrated the \\\"residual\\\" ammonia in the cavity of the duodenal bulb and led to the formation of an ulcer.</p>\",\"PeriodicalId\":23643,\"journal\":{\"name\":\"Wiadomosci lekarskie\",\"volume\":\"78 7\",\"pages\":\"1298-1301\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Wiadomosci lekarskie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36740/WLek/208989\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Wiadomosci lekarskie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36740/WLek/208989","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
目的:对乌克兰武装部队一名27岁士兵十二指肠球部溃疡形成的病例进行分析并提供病理生理学依据。患者和方法:材料和方法:患者收集记忆后,对患者进行全面检查,包括分步ph测定、食管胃十二指肠镜检查、胃4个地形带幽门螺杆菌感染检查(脲酶试验和镜检染色涂片-指纹),并对同一区域的胃粘膜进行组织学检查。结果:结果:在收集家族史时,发现父系和祖父系均有溃疡病史。据证实,在持续3周的恶化前夕,这名士兵帮助装载一辆汽车,多次将装有20公斤弹药的箱子抬到1.5米的高度。在ph测定中发现,胃液的酸度水平与总酸度的基础正常酸度相对应。食管胃十二指肠镜检查诊断如下:活动期十二指肠球部溃疡(位于中间三分之一,沿后壁,1.5 x 0.8 cm,溃疡缺损被灰色纤维蛋白覆盖)。红斑的duodenogastropathy。胰腺病变的间接迹象。”经胃黏膜组织学检查证实,患者在活动期存在慢性胃炎。胃炎类型(非萎缩性)通过HP感染检测确认,HP感染显示在胃的所有4个地形带中都有高浓度的活性形式细菌-(+++)。结论:参与军事行动的应激导致幽门螺杆菌感染的活跃繁殖,从而导致胃内“残留”氨的增加。剧烈的体力消耗,伴随着前腹壁肌肉的急剧收缩,产生了“风箱”效应,将“残余”氨集中在十二指肠球腔中,导致溃疡的形成。
A case of duodenal bulb ulcer formation in a soldier of the ukrainian armed forces during ammunition loading.
Objective: Aim: Conduct an analysis and provide a pathophysiological justification for the case of the formation of an ulcer of the duodenal bulb in a 27-year-old soldier of the Armed Forces of Ukraine.
Patients and methods: Materials and Methods: After collecting the anamnesis, the patient underwent a comprehensive examination, which included step-by-step pH-metry, esophagogastroduodenoscopy, testing for Helicobacter pylori infection (HP) (urease test and microscopic examination of stained smears-prints) in 4 topographic zones of the stomach, and histological examination of the gastric mucosa in the same zones.
Results: Results: When collecting a family history, it was found that relatives on one male line - father and grandfather - suffered from ulcer disease. It was established that on the eve of an exacerbation, which lasted 3 weeks, the soldier helped load a car, repeatedly lifting boxes with ammunition up to 20 kg to a height of 1.5 m. During pH-metry it was found that the acidity level of gastric juice corresponded to the basal normacidity of total. During esophagogastroduodenoscopy the following diagnosis was made: "Ulcer of the duodenal bulb in the active stage (in the middle third, along the back wall, 1.5 x 0.8 cm, the ulcer defect is covered with gray fibrin). Erythematous duodenogastropathy. Indirect signs of pancreatopathy." The presence of chronic gastritis in the active stage in the patient was confirmed by the results of histological examination of the gastric mucosa. The type of gastritis (non-atrophic) was confirmed by testing for HP infection, which revealed a high concentration of the active form of bacteria - (+++) in all 4 topographic zones of the stomach.
Conclusion: Conclusions: Stress associated with participation in military operations led to the active reproduction of Helicobacter pylori infection and, accordingly, an increase in "residual" ammonia in the stomach cavity. Heavy physical exertion, which was accompanied by a sharp contraction of the muscles of the anterior abdominal wall, created a "bellows" effect, which concentrated the "residual" ammonia in the cavity of the duodenal bulb and led to the formation of an ulcer.