Alexandra F Belotta, Shannon Beazley, Matthew Hutcheson, Monique Mayer, Hugues Beaufrère, Sally Sukut
{"title":"Comparison of sedation and general anesthesia protocols for <sup>18</sup>F-FDG-PET/CT studies in dogs and cats: Musculoskeletal uptake and radiation dose to workers.","authors":"Alexandra F Belotta, Shannon Beazley, Matthew Hutcheson, Monique Mayer, Hugues Beaufrère, Sally Sukut","doi":"10.1111/vru.13439","DOIUrl":"https://doi.org/10.1111/vru.13439","url":null,"abstract":"<p><p>In veterinary medicine, PET/CT scans are generally performed with the patient under general anesthesia. The aim of this prospective crossover study was to compare the musculoskeletal uptake of <sup>18</sup>F-FDG and radiation doses to workers during PET/CT studies of healthy dogs and cats between sedation and general anesthesia. Volume and maximal standard uptake values (SUVmax) values of abnormal <sup>18</sup>F-FDG uptake in the skeletal musculature, presence of misregistration artifact, and radiation doses to workers for each PET/CT study were recorded. Sedation was associated with increased volume of <sup>18</sup>F-FDG uptake in the musculature of the thoracic limbs (p = .01), cervical (p = .02), and thoracic (p = .03) spine. Increased volume and SUVmax of the musculature assessed altogether were associated with the lighter degree of sedation (p = .04 for both). A significant decrease in the odds of misregistration artifact was observed for anesthetized animals in comparison with sedated (OR: 0.0, 95% CI: 0.0-0.0, p = .01). Radiation doses to workers were significantly higher for sedation compared with general anesthesia (p = .01) and for the anesthesia technician compared with the nuclear medicine technologist (p = .01). Use of sedation for PET/CT studies in dogs and cats is feasible. However, it is associated with increased physiologic musculoskeletal uptake of <sup>18</sup>F-FDG in the thoracic limbs, cervical, and thoracic spine, with increased frequency of misregistration artifact, and with increased radiation doses to workers. These limitations can be overcome by recognition of the uptake pattern and monitoring/rotation of the involved staff at institutions where a high caseload is expected.</p>","PeriodicalId":23581,"journal":{"name":"Veterinary Radiology & Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pablo Espinosa Mur, Ryan Appleby, Kathryn L Phillips, Ameet Singh, Gabrielle Monteith, Lindsey J Gilmour, Erin Keenihan, Lise Daniaux, Alex Zur Linden
{"title":"Radiographic findings in dogs with 360 degrees gastric dilatation and volvulus.","authors":"Pablo Espinosa Mur, Ryan Appleby, Kathryn L Phillips, Ameet Singh, Gabrielle Monteith, Lindsey J Gilmour, Erin Keenihan, Lise Daniaux, Alex Zur Linden","doi":"10.1111/vru.13445","DOIUrl":"https://doi.org/10.1111/vru.13445","url":null,"abstract":"<p><p>Gastric dilatation and volvulus (GDV) is a life-threatening emergency that requires urgent intervention. Radiographic features associated with 360-GDV in dogs have not been investigated. The aim of this retrospective observational study is to describe radiographic features and clinical variables in dogs affected with 360-GDV and to report agreement rates between different radiologists. We also report the sensitivity and specificity of radiographs to diagnose 360-GDV in dogs. Confirmed 360-GDV cases were retrieved, and the radiographic findings were compared with dogs presenting with gastric dilatation (GD) and 180-GDV. Images were reviewed and graded by three blinded board-certified radiologists. A total of 16 dogs with confirmed 360-GDV were identified. The median age was 10 years old (2-13 years). The sensitivity for detection of 360-GDV ranged between 43.7% and 50%, and the specificity between 84.6% and 92.1%. Interobserver agreement on final diagnosis was substantial (Kappa = 0.623; 0.487-0.760, 95% CI). The highest agreement rate was in cases of 180-GDV (87%), followed by the GD cases (72%) and 360-GDV (46%). Severe esophageal distension and absence of small intestinal dilation were the only radiographic features specifically associated with 360-GDV. A similar pyloric position was found between GD and 360-GDV. Additional radiographic variables that could help differentiate GD from 360-GDV include the degree of gastric distension and the peritoneal serosal contrast. Two cases with 360-GDV were misdiagnosed by the three radiologists as GD. In conclusion, radiographically, 360-GDV cases can reassemble GD and vice versa. Radiologists and clinicians should be aware of the low sensitivity of radiographs for the detection of 360-GDV.</p>","PeriodicalId":23581,"journal":{"name":"Veterinary Radiology & Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bethany Guy, Paul Freeman, Sam Khan, Marie-Aude Genain
{"title":"The effect of midline shift on survival time in dogs with structural brain disease diagnosed on MRI.","authors":"Bethany Guy, Paul Freeman, Sam Khan, Marie-Aude Genain","doi":"10.1111/vru.13450","DOIUrl":"https://doi.org/10.1111/vru.13450","url":null,"abstract":"<p><p>The effect of midline shift identified on brain MRI on survival time in dogs with structural brain disease is relatively unknown. This retrospective single-centered cohort study reviewed medical and imaging data of 77 dogs with structural brain lesions evident on MRI. Images were reviewed for the presence of midline shift, brain edema, foramen magnum herniation, and ventriculomegaly. Kaplan-Meier method and Cox regression analysis were undertaken to compare survival between dogs with and without midline shift. Midline shift was present in 40 of 77 (52%) dogs and absent in 37 of 77 (48%). Univariate analysis revealed that dogs with midline shift had a median survival time of 34.5 days (95% CI, 4-108 days) compared with 241 days (95% CI, 133,- days) in dogs without midline shift (hazard ratio = 2.67, 95% CI, 1.5-4.49). Multivariate Cox regression analysis revealed a hazard ratio of 3.6 (95% CI, 1.7-7.6; P-value < .001) for dogs with midline shift. Shorter median survival times remained significant in all groups after segregation based on etiological diagnosis. The significantly shorter survival times observed herein for dogs with midline shifts, regardless of etiologic cause, provide further evidence that midline shift holds value as a negative prognostic factor in diagnostic imaging.</p>","PeriodicalId":23581,"journal":{"name":"Veterinary Radiology & Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kayla Le, Victoria Riggs, Seng Wai Yap, Martina Ernestova, Kimberley Sebastian
{"title":"Computed tomographic features of severe horn infection in a male Scimitar-horned oryx (Oryx dammah).","authors":"Kayla Le, Victoria Riggs, Seng Wai Yap, Martina Ernestova, Kimberley Sebastian","doi":"10.1111/vru.13440","DOIUrl":"https://doi.org/10.1111/vru.13440","url":null,"abstract":"<p><p>A 3-year-old male Scimitar-horned oryx presented for evaluation of an acutely deformed right horn with right head tilt and right facial pain. Computed tomographic evaluation revealed an increased volume of central fluid/soft tissue attenuation with gas-attenuating foci within the right horn. The right horn was amputated at the right horn base. Imaging and histopathologic features were consistent with emphysematous osteomyelitis. Following treatment, the patient returned to normal behavior. This is the first veterinary report describing the computed tomographic features of a horn infection in a Scimitar-horned oryx.</p>","PeriodicalId":23581,"journal":{"name":"Veterinary Radiology & Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142393686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maxime Vandersmissen, Laurence Evrard, Alexandre Charles, Fabrice Audigié, Valeria Busoni
{"title":"Diagnostic imaging findings in lame Warmblood horses with bone injuries of the medial proximal phalanx glenoid cavity.","authors":"Maxime Vandersmissen, Laurence Evrard, Alexandre Charles, Fabrice Audigié, Valeria Busoni","doi":"10.1111/vru.13449","DOIUrl":"https://doi.org/10.1111/vru.13449","url":null,"abstract":"<p><p>This retrospective study aims to describe baseline and follow-up imaging findings in subchondral and trabecular bone damage occurring outside of the sagittal groove in the proximal phalanx (P1) glenoid in a case series of lame Warmblood horses. Thirteen lame horses (16 forelimbs) with standing magnetic resonance imaging (sMRI) evidence of nonsagittal groove glenoid subchondral and trabecular bone injury of P1 as the main lesion were included. All injuries were located at the medial aspect of the P1 glenoid. At sMRI, changes included subchondral bone plate thickening and trabecular sclerosis, bone marrow edema-like signal, subchondral bone resorption (11/16), and new bone production (8/16). Subchondral bone resorption in the transverse plane was linear (8/11), round (2/11), or ill-defined (1/11). Sclerosis, bone resorption, and new bone production were seen radiographically in 10, 4, and 5 limbs, respectively. All limbs had concurrent metacarpal condyle sMRI imaging abnormalities, osteophytosis, and joint effusion. Follow-up sMRIs were obtained in 8 of 16 limbs, five of which showing progression of the resorptive lesion. One horse encountered a comminuted fracture of the affected P1 18 months after the follow-up sMRI examination. The imaging appearance of the medial glenoid bone injuries of P1 in this case series is consistent with chronic bone overload. The linear configuration of bone resorption seen in eight lesions suggests short, incomplete stress fractures, which is supported by the ultimate catastrophic fracture occurring in one case.</p>","PeriodicalId":23581,"journal":{"name":"Veterinary Radiology & Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142393687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ellen Law, Linda Wright, Margareta Uhlhorn, Elin Hernlund, Carolina Nilemo, Marie Rhodin
{"title":"Hypoechoic ultrasonographic findings in the patellar ligaments are common in riding and trotting horses in training (116 cases).","authors":"Ellen Law, Linda Wright, Margareta Uhlhorn, Elin Hernlund, Carolina Nilemo, Marie Rhodin","doi":"10.1111/vru.13446","DOIUrl":"https://doi.org/10.1111/vru.13446","url":null,"abstract":"<p><p>Patellar ligament (PL) injuries are increasingly being reported in horses, but few studies have described the normal PL ultrasonographic appearance in horses. The aims of this prospective observational study were to describe the ultrasonographic appearance of the PLs and infrapatellar fat pad in a population of horses in training and to relate the ultrasonographic findings to objectively measured movement asymmetry. B-mode and color Doppler ultrasonographic examination of the PLs and infrapatellar fat pad in both hind limbs and objective gait analyses were performed on the 116 riding and trotting horses included in the study. The association between ultrasonographic findings, horse age, and movement asymmetry during the trot was then investigated. Distinct or diffuse hypoechoic regions were commonly found in the intermediate PL (24/116; 20.7%), especially in the caudal aspect of the mid-third of the ligament. The infrapatellar fat pad had a hypoechoic striated appearance in all horses except one, in which it was hyperechoic. No association was found between ultrasonographic findings in the PLs and infrapatellar fat pad and lameness. It is important to recognize that there is biological variation in PL appearance, which may or may not be associated with pain in this area, therefore emphasizing the use of local analgesia to determine the location of the lameness.</p>","PeriodicalId":23581,"journal":{"name":"Veterinary Radiology & Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142393688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diego Darley Velasquez Piñeros, Aymara Eduarda de Lima, Anderson Fernando de Souza, Rubens Peres Mendes, Maurício José Bittar, Silvio Henrique de Freitas, Thiago Bernardino, Rodrigo Romero Corrêa
{"title":"Radiographic anatomy of the nasal conchal bullae and conchal sinuses in mature horses.","authors":"Diego Darley Velasquez Piñeros, Aymara Eduarda de Lima, Anderson Fernando de Souza, Rubens Peres Mendes, Maurício José Bittar, Silvio Henrique de Freitas, Thiago Bernardino, Rodrigo Romero Corrêa","doi":"10.1111/vru.13442","DOIUrl":"https://doi.org/10.1111/vru.13442","url":null,"abstract":"<p><p>The dorsal and ventral nasal conchal bullae and conchal sinuses are part of the complex equine paranasal sinus system and are commonly affected by secondary sinusitis. However, the radiographic anatomy of the conchal sinuses is poorly reported in the literature. The present study aimed to describe the radiographic anatomical characteristics of the nasal conchal bullae and conchal sinuses in mature horses. Six equine cadaveric heads without sinus or dental disorders were studied. A maxillary sinusotomy was performed to identify the dorsal and ventral nasal conchal bullae and conchal sinuses, allowing the application of radiopaque contrast medium in these structures. Afterward, the same projections were repeated. Laterolateral views allowed an adequate visualization of nasal conchal bullae and conchal sinuses; however, they overlapped the same contralateral structure. In the latero30°dorsal- lateroventral oblique view, the same structures were easily recognizable, but in an oblique view, the structures were projected dorsally in relation to the contralateral one. The dorsoventral view allowed partial visualization of the dorsal conchal bullae and dorsal sinuses, but it was not possible to identify the ventral conchal sinus and ventral conchal bullae. The offset dorsoventral view helped in the identification of the dorsal conchal bullae and dorsal conchal sinus, also achieving visualization of the medial region of the ventral conchal sinus and ventral conchal bullae. The use of contrast medium, added to the anatomical dissection, allowed a better radiographic identification of the sinuses and conchal bullae. The combination of different radiographic views is recommended for the evaluation of these structures.</p>","PeriodicalId":23581,"journal":{"name":"Veterinary Radiology & Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142376110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasonographic assessment of equine metacarpal cartilage thickness is more accurate than computed tomographic arthrography.","authors":"Seamus Hoey, Ursula Fogarty, Hester McAllister, Antonella Puggioni, Brian Cloak, Hélène Richard, Cliona Skelly, Sheila Laverty","doi":"10.1111/vru.13444","DOIUrl":"https://doi.org/10.1111/vru.13444","url":null,"abstract":"<p><p>Articular cartilage can be directly imaged using ultrasonography. The fetlock is a common site of osteochondrosis, with the sagittal ridge of the third metacarpal bone most commonly affected. In osteochondrosis, cartilage thickening may be an initial finding. This postmortem study investigated the ability of ultrasonography to accurately measure the dorsodistal articular cartilage of the third metacarpal bone in young horses, compared to computed tomographic arthrography (CTA) and histological measurements. A total of 33 metacarpophalangeal joints from 18 horses between the ages of 12 days and 10 months old were imaged ultrasonographically and with CTA and sectioned and measured using histology. Imaging measurements were made by two observers. Despite overall weak agreement between ultrasonography and histology, the best agreement was at the distal aspect of the sagittal ridge of the third metacarpal bone. Interobserver agreement at this site was also moderate. CTA showed poor agreement overall with histology. Cartilage thickness decreased with age on ultrasonography, CTA, and histology. In conclusion, ultrasonography is a more accurate imaging modality than CTA in the assessment of cartilage in young horses.</p>","PeriodicalId":23581,"journal":{"name":"Veterinary Radiology & Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142376111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kreig Embriano, Merrilee Holland, Kayla M Corriveau, Eric Hofmeister, Jess McCarthy
{"title":"Shear-wave elastography of canine patellar tendons in healthy dogs and the influence of stifle joint angle.","authors":"Kreig Embriano, Merrilee Holland, Kayla M Corriveau, Eric Hofmeister, Jess McCarthy","doi":"10.1111/vru.13447","DOIUrl":"https://doi.org/10.1111/vru.13447","url":null,"abstract":"<p><p>Elastography is a sonographic modality that measures tissue stiffness, a mechanical property of tissues, and a biomarker for disease. Canine musculoskeletal application to the patellar tendon has been limited to semiqualitative strain elastography. This prospective study aimed to quantitatively evaluate patellar tendon stiffness using shear-wave elastography with a color map superimposed over the tendon, a propagation map for quality control, and measurements at specific regions of interest in 16 clinically normal sedated dogs weighing 25 kg or greater. Tendon stiffness using shear-wave elastography (SWE) was assessed at different stifle angles and in three regions to determine if angle and location affected stiffness. All dogs were screened with general and orthopedic exams, lateral stifle radiographs, and patellar tendon 2D ultrasound. Shear-wave elastography was performed from a long axis at various stifle angles at the proximal, middle, and distal tendon segments. Quality diagnostic SWE results varied significantly with stifle angle, and 150° of extension was the only angle found to be clinically useful based on the ease of obtaining measurable results and a quality control propagation wave. Patellar tendons were primarily stiff with a red color elastogram. The proximal and middle segments, measured at various angles, had a mean SWE velocity of 7.32 ± 0.90 m/s. Tendon stiffness did not differ along tendon length when measured in greater extension. However, stiffness decreased in the middle segment of the tendon at 150° when compared with 120°. This study establishes a quantitative baseline of normal patellar tendon stiffness to compare with pathologic states.</p>","PeriodicalId":23581,"journal":{"name":"Veterinary Radiology & Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeryl Jones, Ahmed Ali, Cerano Harrison, Guillermo Rimoldi
{"title":"Radiographic, computed tomographic, and histologic characteristics of bone for clinically normal laying hens in a free-range housing system.","authors":"Jeryl Jones, Ahmed Ali, Cerano Harrison, Guillermo Rimoldi","doi":"10.1111/vru.13443","DOIUrl":"https://doi.org/10.1111/vru.13443","url":null,"abstract":"<p><p>Laying hens are increasingly being kept in backyard flocks and considered family pets; however, diagnostic imaging characteristics of bone for clinically normal backyard hens are currently limited. This prospective, descriptive study was to describe radiographic, computed tomographic, and histologic characteristics of bone for a group of clinically normal laying hens housed in conditions comparable to those of backyard flocks. Sixteen 60-week-old Lohmann Brown laying hens were included. Hens were housed in a free-range unit with outdoor access at a university research and teaching farm. Hens were defined as clinically normal by the farm manager and a veterinary researcher in laying hen behavior and welfare. Findings from the horizontal beam, left lateral, sternal radiographs (n = 16), postmortem, and whole-body CT scans (n = 4) were recorded by a veterinary radiologist and a research technician. Histologic findings for sternal, femoral, and tibiotarsal bone samples (n = 5) were recorded by a veterinary pathologist. The most frequent radiographic findings for the sternal carina (keel bone) were smoothly marginated concave deviations of the ventral margin and caudal section fractures. Multiple punctate mineral opacities (PMOs) were present in radiographs and CT images for all hens and were involved in the sternal carina and multiple other bones in the axial and appendicular skeleton. No bone abnormalities were identified in any histologic sections where PMOs were radiographically detected. Authors propose that PMOs are normal radiographic and CT findings in the bones of mature, laying hens and may represent temporary calcium reservoirs formed during osteoclastic activities.</p>","PeriodicalId":23581,"journal":{"name":"Veterinary Radiology & Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}