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[ADHD and problematic substance use]. [注意力缺陷多动症和有问题的药物使用]。
Ugeskrift for laeger Pub Date : 2025-05-12 DOI: 10.61409/V01250005
Simon Hjerrild, Sanne Wissing, Tine Holm
{"title":"[ADHD and problematic substance use].","authors":"Simon Hjerrild, Sanne Wissing, Tine Holm","doi":"10.61409/V01250005","DOIUrl":"https://doi.org/10.61409/V01250005","url":null,"abstract":"<p><p>Attention Deficit Hyperactivity Disorder (ADHD) often coexists with problematic substance use, such as harmful use or dependency. In this review, studies estimate a 21% prevalence of ADHD among individuals with problematic substance use, who often exhibit earlier substance initiation, faster dependency transitions, and higher relapse risks. Diagnosis and treatment are challenging due to overlapping symptoms and comorbidities, but integrated, case-managed approaches combining psychosocial, pharmacological, and therapeutic interventions show promise in improving outcomes for this vulnerable population.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The importance of gender and age for symptoms and epidemiology of ADHD]. 性别和年龄对ADHD症状和流行病学的重要性。
Ugeskrift for laeger Pub Date : 2025-05-12 DOI: 10.61409/V11240761
Andreas Hoff, Helene Speyer
{"title":"[The importance of gender and age for symptoms and epidemiology of ADHD].","authors":"Andreas Hoff, Helene Speyer","doi":"10.61409/V11240761","DOIUrl":"https://doi.org/10.61409/V11240761","url":null,"abstract":"<p><p>ADHD is a descriptive diagnosis encompassing diverse symptom profiles with unclear etiology and varying prevalence estimates. This review outlines that evidence suggests diagnostic and treatment practices differ by age and gender, with a marked increase in adult diagnoses and higher treatment rates-especially among women-than cohort studies predict. This may indicate overdiagnosis. Given the diagnostic uncertainty and risk of overtreatment, particularly with rising societal performance demands, more stringent diagnostic criteria and individualised treatment approaches are recommended.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Non-pharmacological interventions for ADHD]. [ADHD的非药物干预]。
Ugeskrift for laeger Pub Date : 2025-05-12 DOI: 10.61409/V11240798
Niels Bilenberg, Aida Bikic, Anne Mette Lange
{"title":"[Non-pharmacological interventions for ADHD].","authors":"Niels Bilenberg, Aida Bikic, Anne Mette Lange","doi":"10.61409/V11240798","DOIUrl":"https://doi.org/10.61409/V11240798","url":null,"abstract":"<p><p>ADHD is a common neurodevelopmental disorder with a negative impact on life trajectory. While medication is the most evidence-based treatment, multimodal intervention is strongly recommended. This review focuses on non-pharmacological interventions for ADHD that have been investigated in recent reviews and meta-analyses. In an individualised case management approach, it may be relevant to include interventions that are not (yet) evidence-based if personal factors indicate benefit. Clinicians should continuously monitor responses to interventions and adjust or add interventions to optimise outcomes.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Overlap between PTSD, ADHD, and narcolepsy]. [PTSD， ADHD和嗜睡症的重叠]。
Ugeskrift for laeger Pub Date : 2025-05-12 DOI: 10.61409/V10240757
Tania Mariager, Helene Speyer, Laura Ponsaing
{"title":"[Overlap between PTSD, ADHD, and narcolepsy].","authors":"Tania Mariager, Helene Speyer, Laura Ponsaing","doi":"10.61409/V10240757","DOIUrl":"https://doi.org/10.61409/V10240757","url":null,"abstract":"<p><p>This case report describes the diagnosis of ADHD in a 29-year-old woman suffering from psychiatric and metabolic conditions and type 2 diabetes, receiving treatment for severe PTSD. She developed excessive daytime sleepiness, which, due to diagnostic overshadowing, initially was attributed to her psychiatric illness, delaying diagnosis and treatment. This jeopardized her daily life due to incidents of sudden sleep attacks and much longer sleeping times. The diagnosis of narcolepsy type 2 was given based on polysomnography, multiple sleep latency tests, and examination of the cerebrospinal fluid. Treatment with methylphenidate was successful in reducing her excessive daytime sleepiness and, to some extent, her excessive need to sleep.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Risk of cardiovascular disease associated with ADHD treatment]. [与ADHD治疗相关的心血管疾病风险]。
Ugeskrift for laeger Pub Date : 2025-05-12 DOI: 10.61409/V11240840
Anders Holt, Morten Lamberts, Hanne Elberling, Helene Gjervig Hansen
{"title":"[Risk of cardiovascular disease associated with ADHD treatment].","authors":"Anders Holt, Morten Lamberts, Hanne Elberling, Helene Gjervig Hansen","doi":"10.61409/V11240840","DOIUrl":"https://doi.org/10.61409/V11240840","url":null,"abstract":"<p><p>Risk of cardiovascular side effects associated with the agonistic effect on the sympathetic nervous system provided by the medical treatment of ADHD is continuously debated. Any causal relationship has yet to be proven but observational findings suggest an increased risk of cardiovascular disease associated with treatment - especially higher doses over longer periods. Follow-up with clinical assessment, blood pressure, and resting heart rate is advised. Electrocardiograms and measurements of lipid- and HbA1c levels might also often be advisable in adults, as argued in this review.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[ADHD and personality disorders]. [多动症和人格障碍]。
Ugeskrift for laeger Pub Date : 2025-05-12 DOI: 10.61409/V02250082
Erik Simonsen, Janne Walløe Vilmar, Mickey Kongerslev
{"title":"[ADHD and personality disorders].","authors":"Erik Simonsen, Janne Walløe Vilmar, Mickey Kongerslev","doi":"10.61409/V02250082","DOIUrl":"https://doi.org/10.61409/V02250082","url":null,"abstract":"<p><p>ADHD and personality disorders, like emotional unstable personality disorder and dissocial personality disorder, overlap to some extent but they also commonly co-occur in clinical populations. Prevalences, key issues in differential diagnosis, and the different aetiological background of the two categories are presented in this review. In depth, clinical diagnostic evaluation of both disorder syndromes, not only based on use of questionnaires, is needed to sufficiently distinct the separate main categories. In case of co-occurrence treatment, recommendations of both disorders and social support should be considered to achieve a patient-centered approach of the specific needs.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stigningen i ADHD-diagnoser kalder på faglig refleksion og forskningsmæssig oprustning.
Ugeskrift for laeger Pub Date : 2025-05-12 DOI: 10.61409/V04250335
Simon Hjerrild
{"title":"Stigningen i ADHD-diagnoser kalder på faglig refleksion og forskningsmæssig oprustning.","authors":"Simon Hjerrild","doi":"10.61409/V04250335","DOIUrl":"https://doi.org/10.61409/V04250335","url":null,"abstract":"","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Untreated arthritis urica can cause foot ulcers and amputations in patients with diabetes]. [未经治疗的尿关节炎会导致糖尿病患者的足部溃疡和截肢]。
Ugeskrift for laeger Pub Date : 2025-05-05 DOI: 10.61409/V11240823
Mie Cecilie Hall Jensen, Bjarke Risgaard, Hanne Trap Wolf
{"title":"[Untreated arthritis urica can cause foot ulcers and amputations in patients with diabetes].","authors":"Mie Cecilie Hall Jensen, Bjarke Risgaard, Hanne Trap Wolf","doi":"10.61409/V11240823","DOIUrl":"https://doi.org/10.61409/V11240823","url":null,"abstract":"<p><p>This case report describes an 88-year-old male with severe tophaceous gouty arthritis, diabetes, and kidney impairment. Over 20 years, the patient experienced recurrent gout attacks and developed tophaceous deposits, some of which ulcerated. Walking was severely impaired by foot deformities, pain, and chronic foot ulcers. Despite multiple consultations and radiological evidence of gout, no urate-lowering therapy was prescribed. Finally, microscopic analysis of foot ulcer debris identified urate crystals, confirming gout. The patient was then started on allopurinol therapy.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Rehabilitation of alien hand syndrome]. [异手综合征的康复]。
Ugeskrift for laeger Pub Date : 2025-05-05 DOI: 10.61409/V10240672
Rose Stevens, Anne Louise Vandsø Svenningsen, Charlotte Olesen, Rikke Middelhede
{"title":"[Rehabilitation of alien hand syndrome].","authors":"Rose Stevens, Anne Louise Vandsø Svenningsen, Charlotte Olesen, Rikke Middelhede","doi":"10.61409/V10240672","DOIUrl":"10.61409/V10240672","url":null,"abstract":"<p><p>Alien hand syndrome (AHS) is a rare neurological condition characterized by involuntary and uncontrollable movements of an upper limp. Based on clinical presentation and affected brain region, AHS has three variants: frontal, callosal and posterior. Treatment of AHS is based on anecdotal reports and includes clonazepam, botulinum toxin injections, cognitive behavioural therapy, visuospatial coaching, distracting tasks and mirror box therapy. In this case report, we present two patients admitted to rehabilitation with AHS after an ischaemic stroke. One of them received mirror box therapy.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Treatment of rheumatoid arthritis with janus kinase inhibitors]. [用janus激酶抑制剂治疗类风湿性关节炎]。
Ugeskrift for laeger Pub Date : 2025-05-05 DOI: 10.61409/V09240651
Pernille Holme Thorhauge, Lars Løkke Ottesen, Niels Lomborg
{"title":"[Treatment of rheumatoid arthritis with janus kinase inhibitors].","authors":"Pernille Holme Thorhauge, Lars Løkke Ottesen, Niels Lomborg","doi":"10.61409/V09240651","DOIUrl":"https://doi.org/10.61409/V09240651","url":null,"abstract":"<p><p>Rheumatoid arthritis (RA) is a frequent systemic inflammatory polyarthritis. In recent years, considerable knowledge has been gained in the treatment and diagnosis field. This review will address RA in general, focusing on the effect of the newest treatment option: janus kinase (JAK) inhibitors. Furthermore, using JAK inhibitors to treat RA in a Danish context will be discussed. In conclusion, JAK inhibitor treatment is an effective treatment for rheumatoid arthritis - however, potential serious side effects and a high price limit its use.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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