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Diabetic retinopathy. 糖尿病视网膜病变。
Ugeskrift for laeger Pub Date : 2024-09-09 DOI: 10.61409/V04240246
Jakob Grauslund, Nis Andersen, Jens Andresen, Toke Bek, Sara Brandi, Javad Hajari, Søren Tang Knudsen, Caroline Schmidt Laugesen, Majbrit Lind, Mette Slot Nielsen, Katja Schielke, Yousif Subhi
{"title":"Diabetic retinopathy.","authors":"Jakob Grauslund, Nis Andersen, Jens Andresen, Toke Bek, Sara Brandi, Javad Hajari, Søren Tang Knudsen, Caroline Schmidt Laugesen, Majbrit Lind, Mette Slot Nielsen, Katja Schielke, Yousif Subhi","doi":"10.61409/V04240246","DOIUrl":"https://doi.org/10.61409/V04240246","url":null,"abstract":"<p><p>Diabetic retinopathy (DR) is the most common complication in patients with diabetes, and screening for sight-threatening end-stages is indicated to avoid severe visual loss. Screening of DR is nationally implemented in Denmark according to evidence-based national guidelines, which includes the use of individualised screening intervals. Treatment is indicated for proliferative DR and diabetic macular oedema, and treatment modalities include retinal laser therapy, intravitreal angiostatic therapy, and vitrectomy. In this review, we summarise the current guidelines for screening and treatment of DR in Denmark.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Homecare, home monitoring, and hospital-at-home. 家庭护理、家庭监控和医院上门服务。
Ugeskrift for laeger Pub Date : 2024-09-09 DOI: 10.61409/V02240158
Thea Kølsen Fischer, Tatjana Jessen Sandreva, Maria Normand Larsen, Maja Kjær Rasmussen, Thyge Lynghøj Nielsen, Maria Lund Christensen, Jeff Kirk Svane, Kristian Kidholm, Charlotte Demuth von Sydow
{"title":"Homecare, home monitoring, and hospital-at-home.","authors":"Thea Kølsen Fischer, Tatjana Jessen Sandreva, Maria Normand Larsen, Maja Kjær Rasmussen, Thyge Lynghøj Nielsen, Maria Lund Christensen, Jeff Kirk Svane, Kristian Kidholm, Charlotte Demuth von Sydow","doi":"10.61409/V02240158","DOIUrl":"https://doi.org/10.61409/V02240158","url":null,"abstract":"<p><p>The Danish healthcare system is currently undergoing a transformation towards increased use of virtual healthcare services. In this review, we propose a structured risk-stratified model to delineate the differences between homecare, homemonitoring, and hospital-at-home, while discussing their current status and addressing barriers hindering the widespread adoption and scaling of home-based care incl. technological limitations, regulatory complexities, and cultural considerations. We advocate for establishing a national central support function to expedite the shift towards home-based care.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Common efficacy measures and measurement instruments lead to more meaningful clinical research. 通用的疗效测量方法和测量工具有助于开展更有意义的临床研究。
Ugeskrift for laeger Pub Date : 2024-09-09 DOI: 10.61409/V12230799
Dorthe B Berthelsen, Linea Rishøj Thorlacius, Bente Villumsen, Gregor Be Jemec, Robin Christensen
{"title":"Common efficacy measures and measurement instruments lead to more meaningful clinical research.","authors":"Dorthe B Berthelsen, Linea Rishøj Thorlacius, Bente Villumsen, Gregor Be Jemec, Robin Christensen","doi":"10.61409/V12230799","DOIUrl":"https://doi.org/10.61409/V12230799","url":null,"abstract":"<p><p>This review describes that a core outcome set (COS) represents a consensus-based minimum set of outcomes to be collected and reported in clinical trials involving a particular disease or population. A COS serves as a guideline for global consensus on which outcome domains should be collected in all clinical trials. After defining what to measure, it becomes crucial to reach consensus on how to measure it. This includes the selection of appropriate outcome measurement instruments with credible measurement properties and interpretable thresholds of meaning.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aberrant left atrial chorda in a patient with mitral regurgitation requiring surgery. 一名二尖瓣反流患者左心房绒毛异常，需要手术治疗。
Ugeskrift for laeger Pub Date : 2024-09-09 DOI: 10.61409/V02240132
Marie Øbo Larsen, Frederik Thorgaard Uttenthal, Gennady V Atroshchenko
{"title":"Aberrant left atrial chorda in a patient with mitral regurgitation requiring surgery.","authors":"Marie Øbo Larsen, Frederik Thorgaard Uttenthal, Gennady V Atroshchenko","doi":"10.61409/V02240132","DOIUrl":"10.61409/V02240132","url":null,"abstract":"<p><p>We present a rare case of an 84-year-old woman with a left atrial chorda. She was admitted with heart failure and echocardiography revealed severe mitral valve insufficiency due to chordal rupture and prolapse of the posterior leaflet. In addition, a left atrial chorda was diagnosed, attached to the anterior leaflet, restricting the valve and contributing to the insufficiency. The patient underwent surgery with the removal of the atrial chorda and insertion of two neochordae and mitral annuloplasty with a ring. Postoperative echocardiography showed a well-functioning valvuloplasty.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe poisoning with semi-synthetic cannabinoids. 半合成大麻素严重中毒。
Ugeskrift for laeger Pub Date : 2024-09-09 DOI: 10.61409/V04240241
Nanna Reiter, Kristian Linnet, Natasja Østermark Andersen, Brian Schou Rasmussen, Marie Klose Nielsen, Karen Reenberg Eriksen, Dorte Fris Palmqvist
{"title":"Severe poisoning with semi-synthetic cannabinoids.","authors":"Nanna Reiter, Kristian Linnet, Natasja Østermark Andersen, Brian Schou Rasmussen, Marie Klose Nielsen, Karen Reenberg Eriksen, Dorte Fris Palmqvist","doi":"10.61409/V04240241","DOIUrl":"10.61409/V04240241","url":null,"abstract":"<p><p>Recently, semi-synthetic cannabinoids have entered the illegal market and are produced to mimic the psychoactive effects of tetrahydrocannabinol (THC). This is a case report of a 19-year-old man, who was hospitalized due to severe sedation, hypotension and tachy- and bradycardia after ingestion of the semi-synthetic cannabinoids hexahydrocannabinol (HHC) and hexahydrocannabiphorol (HHC-P) mixed in food. HHC-P, HHC and metabolites were identified in blood samples. The amount of semi-synthetic cannabinoids in illegal products can be high, which can explain the described prolonged clinical effects.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cervical spondylotic myelopathy. 颈椎病。
Ugeskrift for laeger Pub Date : 2024-09-02 DOI: 10.61409/V02240149
David Alw Cant, Simon Bøtker Kongsvad Andersen, Kristian Høy
{"title":"Cervical spondylotic myelopathy.","authors":"David Alw Cant, Simon Bøtker Kongsvad Andersen, Kristian Høy","doi":"10.61409/V02240149","DOIUrl":"https://doi.org/10.61409/V02240149","url":null,"abstract":"<p><p>Cervical spondylotic myelopathy (CSM) is a progressive degenerative condition of the cervical spine and the most common cause of spinal cord injury in adults >55 years of age. Degenerative changes in the spine lead to spinal cord compression, resulting in symptoms such as gait instability, loss of dexterity in the hands, weakness, and sensory deficits. Diagnosis is delayed by 2,2-6,3 years and includes clinical examination and imaging such as MRI. Management of CSM is primarily surgical treatment. This review highligths the importance of early recognition and appropriate treatment in optimising patient outcomes.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Helbrede, lindre, trøste – også ved skizofreni. 治疗、舒缓、安慰--也适用于精神分裂症。
Ugeskrift for laeger Pub Date : 2024-09-02 DOI: 10.61409/V205189
Poul Videbech
{"title":"Helbrede, lindre, trøste – også ved skizofreni.","authors":"Poul Videbech","doi":"10.61409/V205189","DOIUrl":"https://doi.org/10.61409/V205189","url":null,"abstract":"","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rhinitis medicamentosa. 药物性鼻炎
Ugeskrift for laeger Pub Date : 2024-09-02 DOI: 10.61409/V04240252
Joachim Birk Munksgaard, Jacob Jessen Christensen, Kasper Aanæs
{"title":"Rhinitis medicamentosa.","authors":"Joachim Birk Munksgaard, Jacob Jessen Christensen, Kasper Aanæs","doi":"10.61409/V04240252","DOIUrl":"https://doi.org/10.61409/V04240252","url":null,"abstract":"<p><p>Sales of over-the-counter decongestant nasal sprays in Denmark from 2011 to 2023 have doubled. This article highlights the potential risks associated with prolonged use of decongestant nasal sprays, such as rhinitis medicamentosa. We conclude that there is an urgent need for increased patient education on proper use and possible side effects of over-the-counter decongestant nasal sprays, as well as a need for more substantial data on side effects related to decongestant nasal sprays to guide health authorities in future regulation.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The prognosis of schizophrenia. 精神分裂症的预后。
Ugeskrift for laeger Pub Date : 2024-09-02 DOI: 10.61409/V02240156
Marie Starzer, Helene Gjervig Hansen, Carsten Hjorthøj, Nikolai Albert, Merete Nordentoft
{"title":"The prognosis of schizophrenia.","authors":"Marie Starzer, Helene Gjervig Hansen, Carsten Hjorthøj, Nikolai Albert, Merete Nordentoft","doi":"10.61409/V02240156","DOIUrl":"https://doi.org/10.61409/V02240156","url":null,"abstract":"<p><p>Psychotic and negative symptoms are core features of schizophrenia but knowledge on the long-term course of these symptoms is lacking. While antipsychotics improve psychotic symptoms, they have limited effect on negative symptoms. Specialized early interventions like OPUS show great effects while ongoing but long-term follow-up indicates no lasting disease-modifying effects. 18% of patients achieved clinical recovery, and 40% obtained symptom remission after 20 years, but high mortality rates and continuous negative symptoms constitute an unmet treatment need, as argued in this review.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D-assisted surgery for reconstruction in the head and neck area. 头颈部重建的 3D 辅助手术。
Ugeskrift for laeger Pub Date : 2024-09-02 DOI: 10.61409/V04240267
Lasse Østrup Petersen, Birgitte Jul Kiil, Søren Dührr Gade, Anders Mølggard Jakobsen, Andreas Engel Krag
{"title":"3D-assisted surgery for reconstruction in the head and neck area.","authors":"Lasse Østrup Petersen, Birgitte Jul Kiil, Søren Dührr Gade, Anders Mølggard Jakobsen, Andreas Engel Krag","doi":"10.61409/V04240267","DOIUrl":"https://doi.org/10.61409/V04240267","url":null,"abstract":"<p><p>Preoperative virtual surgical planning and the use of 3D-printed patient-specific models and cutting guides are increasingly being used in the reconstruction of mandibular defects with a free bone flap. This technology offers several advantages over conventional surgery, such as reduced operating time, reduced bone flap ischaemia time, and the ability to perform more complex and precise reconstructions. This review presents the evidence supporting 3D-assisted surgery for mandibular defect reconstruction and discusses the utilisation of commercial vendors versus in-house 3D-printing solutions.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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