{"title":"[Immunosuppression, pregnancy and listeriosis].","authors":"Lilian Bostlund Olsen, Pernille Langkjær Gormsen, Britta Blume Dolleris, Anne-Louise Lykke Nielsesen, Hanne Katrine Rosbach, Kurt Fuursted, Lise Lotte Torvin Andersen","doi":"10.61409/V05250386","DOIUrl":"https://doi.org/10.61409/V05250386","url":null,"abstract":"<p><p>In this case report on pregnancy-related listeriosis, two women with inflammatory bowel disease and immunosuppression are presented. Both were treated with intravenous ampicillin for three weeks and gentamicin for three days. Continuous fetal monitoring was performed every 12 hours and ultrasound every 3-4 days. Both infants, born at 37 and 33 weeks, required brief CPAP but were clinically unaffected and survived without sequelae. Infant 1 received antibiotics for one week as the mother was two weeks into her treatment regimen, while infant 2 was not treated as the mother had completed her regimen.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145259247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Elisabet Christensen, Liv Bjerre Juul Nielsen, Søren Roepstorff, Erling Oma Dyrholm
{"title":"Colonileus på grund af galdesten.","authors":"Anna Elisabet Christensen, Liv Bjerre Juul Nielsen, Søren Roepstorff, Erling Oma Dyrholm","doi":"10.61409/V73051","DOIUrl":"https://doi.org/10.61409/V73051","url":null,"abstract":"","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145259222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lilian Bostlund Olsen, Pernille Langkjær Gormsen, Britta Dolleris, Anne-Louise Lykke Nielsesen, Hanne Katrine Rosbach, Kurt Fuursted, Lise Lotte Torvin Andersen
{"title":"[Listeria infection and pregnancy].","authors":"Lilian Bostlund Olsen, Pernille Langkjær Gormsen, Britta Dolleris, Anne-Louise Lykke Nielsesen, Hanne Katrine Rosbach, Kurt Fuursted, Lise Lotte Torvin Andersen","doi":"10.61409/V02250139","DOIUrl":"https://doi.org/10.61409/V02250139","url":null,"abstract":"<p><p>L. monocytogenes causes listeriosis, leading to bacteremia, meningitis, and foeto-maternal disease. This review focuses on foeto-maternal infections, presenting an algorithm for investigation, treatment, and follow-up. Treatment involves at least three weeks of IV aminopenicillin, combined with an aminoglycoside for the first three days. Blood cultures are recommended for all patients, and a lumbar puncture for immunocompromised mothers and all infants. The right time for delivery can be discussed, but induction/delivery after GA 37+0 is proposed, preferably after timely antibiotic treatment.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145259185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[New options in the treatment of chronic cough].","authors":"Ole Hilberg, Sofie Wolsing, Anders Løkke Ottesen","doi":"10.61409/V02240104","DOIUrl":"https://doi.org/10.61409/V02240104","url":null,"abstract":"<p><p>During the last ten years, there has been generated a lot of insights in the mechanisms and pathophysiology behind chronic cough. In some countries, tertiary cough clinics have been established, but not in Denmark. This review finds it is important to have a diagnostic workup that is in balance with the national healthcare system. The neuroplasticity of the brain may enhance cough and cause the cough hypersensitivity syndrome. The development of drugs targeting the P2X3 receptor will hopefully introduce a new era in the treatment of chronic cough.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145259270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Treatment when the epidural catheter breaks].","authors":"Kirsten Lerche Voogd, Nanna Marie Christiansen, Neel Walløe, Torben Slott Jensen, Signe Bruun","doi":"10.61409/V02250107","DOIUrl":"https://doi.org/10.61409/V02250107","url":null,"abstract":"<p><p>Labour epidural analgesia is the gold standard of intrapartum analgesia used in approximately 30% of Danish births. In rare cases, the epidural catheter may break during insertion or removal. This is a case report of a 31-year-old first-time pregnant woman in which the epidural catheter broke during removal. She did not present with any neurological symptoms, but a CT revealed the catheter tip in the ligamentum flavum. Two months postpartum, she was still without any symptoms, and a neurosurgical assessment indicated that surgery was unnecessary.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145259263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Cathrine Christoffersen Ravn, Annemette Geilager Abild-Nielsen, Michael Alan Victor, Harald William Meyer
{"title":"[Private exposure and elimination of environmental triggers in mother and son with hypersensitivity pneumonitis].","authors":"Laura Cathrine Christoffersen Ravn, Annemette Geilager Abild-Nielsen, Michael Alan Victor, Harald William Meyer","doi":"10.61409/V04250279","DOIUrl":"https://doi.org/10.61409/V04250279","url":null,"abstract":"<p><p>Hypersensitivity pneumonitis (HP) is an inflammatory lung disease caused by an immune reaction to inhaled antigens. This case report describes a rare occurrence of HP in a mother and her adult son living together. The 59-year-old mother and her 18-year-old son developed HP due to exposure to mold and bird feathers. Both were treated with prednisolone, and the environmental triggers were eliminated. This case highlights the importance of identifying environmental triggers, ensuring follow-up, and considering non-occupational exposures in the HP diagnosis and management of HP.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 40","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Functional testosterone deficiency in relative energy deficiency in sport].","authors":"Loa Nordkap, Nasima Zuhal Olawi, Niels Jørgensen","doi":"10.61409/V10240663","DOIUrl":"https://doi.org/10.61409/V10240663","url":null,"abstract":"<p><p>Relative energy deficiency in sport (REDs) is a syndrome describing dysfunction in normal physiology related to the term \"negative energy availability\" because of a mismatch between energy consumption and expenditure in sport. A disruption of the hypothalamic-pituitary-testes axis, resulting in testosterone deficiency, seems like the dominant feature in males. REDs-associated testosterone deficiency is functional, and treatment should aim towards reducing training and increasing energy consumption, as argued in this review. Testosterone treatment should not be initiated.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 40","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Acute abdomen with findings of pneumococcal peritonitis].","authors":"Marlene Aagaard Hansen, Michelle Meier","doi":"10.61409/V04250301","DOIUrl":"https://doi.org/10.61409/V04250301","url":null,"abstract":"<p><p>A healthy 20-year-old man was admitted with abdominal pain and fever. He had signs of peritoneal irritation, and blood tests showed elevated infection markers. Laparoscopy revealed purulent peritonitis of unclear cause. Blood cultures grew Streptococcus pneumoniae. He improved rapidly with antibiotics. This case highlights a rare manifestation of pneumococcal disease - peritonitis in an unusual subject; a young, previously healthy patient without risk factors. Following recovery, he was vaccinated against pneumococci.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 40","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Seponering af blodtrykssænkende medicin hos ældre – primum non nocere.","authors":"Bo Christensen","doi":"10.61409/V05250377","DOIUrl":"https://doi.org/10.61409/V05250377","url":null,"abstract":"","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 40","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charlotte Vallentin Rosenstock, Henning Bay Nielsesn
{"title":"[Frailty should be assessed before surgery].","authors":"Charlotte Vallentin Rosenstock, Henning Bay Nielsesn","doi":"10.61409/V03250198","DOIUrl":"https://doi.org/10.61409/V03250198","url":null,"abstract":"<p><p>The surgical population is ageing, and preoperative surgical evaluation is limited in its risk prediction ability of perioperative complications. Increasing age results in an increased risk of frailty. Guidelines suggest that frailty should be assessed before surgery. Different frailty scales are described as suggestions for risk-stratification. The frail patient should be offered shared decision-making prior to surgery. Preoperative optimisation programs, i.e. prehabilitation, may benefit patients with frailty, but further research studies examining these perspectives are warranted, as argued in this review.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 40","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}