Pernille Rønn Hoeck, Lars Vedel Kessing, Anne Katrine Pagsberg, Marie Louise Max Andersen
{"title":"15-year-old girl with bipolar affective disorder treated with ECT.","authors":"Pernille Rønn Hoeck, Lars Vedel Kessing, Anne Katrine Pagsberg, Marie Louise Max Andersen","doi":"10.61409/V02240137","DOIUrl":"https://doi.org/10.61409/V02240137","url":null,"abstract":"<p><p>This case report is about the treatment of a 15-year-old girl who presented with mixed episode of bipolar affective disorder dominated by symptoms of mania. Initial treatment with lithium and multiple antipsychotic medications was not effective and was complicated by uncommon and unwanted side effects. The patient was treated with ECT combined with reduced and discontinued doses of antipsychotics, which resulted in measurable positive effects.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frederik Elbke Hansen, Magnus Ploug, Gitte Maria Jørgensen, John Gásdal Karstensen, Ove B Schaffalitzky de Muckadell, Stig Borbjerg Laursen
{"title":"Endoscopic treatment options in peptic ulcer bleeding.","authors":"Frederik Elbke Hansen, Magnus Ploug, Gitte Maria Jørgensen, John Gásdal Karstensen, Ove B Schaffalitzky de Muckadell, Stig Borbjerg Laursen","doi":"10.61409/V04240254","DOIUrl":"https://doi.org/10.61409/V04240254","url":null,"abstract":"<p><p>This review evaluates the evidence for the use of over-the-scope clips (OTSC), topical haemostatic agents (THA), and prophylactic embolisation (PE) in patients with peptic ulcer bleeding (PUB). The use of OTSC and THA may have the potential to increase the rate of endoscopic haemostasis in PUB not responding to conventional endoscopic treatment. In patients at high risk of recurrent bleeding, the performance of PE after achieving endoscopic haemostasis can reduce the risk of rebleeding and the need for surgery. Implementation of a local treatment protocol including these modalities may improve patient outcomes.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Developmental stuttering in adults.","authors":"Thomas Bauer Mølgaard, Lone Baandrup","doi":"10.61409/V03240229","DOIUrl":"https://doi.org/10.61409/V03240229","url":null,"abstract":"<p><p>Developmental stuttering is characterized by early childhood onset with repetition of syllables, prolongations, and blockades as well as secondary behavioural abnormalities. Early therapy is important while there is no approved pharmacological approach. Studies associate developmental stuttering with dopamin surplus in the striatum causing dysfunction of cortical speech areas. Consequently, antidopaminergic agents are being investigated to improve symptoms. The evidence in adults is comprised of few studies of poor quality but might hold promise as a new treatment option, as argued in this review.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quetiapine-induced urinary retention.","authors":"Stine Norup, Sara Buttrup Rosenquist, Trine Reippuert Knudsen, Mette Viller Thorgaard","doi":"10.61409/V04240243","DOIUrl":"https://doi.org/10.61409/V04240243","url":null,"abstract":"<p><p>A 22-year-old woman, known to have a BMI of 12 kg/m2 and a personality disorder, developed urinary retention on a normal dose of quetiapine. She had earlier tolerated a dose of 800 mg quetiapine without complications. The daily dose was 600 mg in combination with oxazepam and zolpidem. Reduction had no effect. The patient intervened with intermittent urinary catheterization the next 19 months. Normal urinary function returned three days after the last dose of quetiapine 25 mg. This case report shows that patients with a low BMI may be more receptive of the anticholinergic effects of quetiapine.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Asymptomatisk tilfældigt fund af guidewiretip i pulmonalt kar.","authors":"Camilla Engelsmann, Niels Bjørn Dalsgaard, Shailesh Balasaheb Kolekar","doi":"10.61409/V72037","DOIUrl":"10.61409/V72037","url":null,"abstract":"","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Astrid Kerstine Buch, Simon Bernth-Andersen, Jan M Krzak
{"title":"Bilateral femoral hernia in a five-year-old boy.","authors":"Astrid Kerstine Buch, Simon Bernth-Andersen, Jan M Krzak","doi":"10.61409/V03240160","DOIUrl":"https://doi.org/10.61409/V03240160","url":null,"abstract":"<p><p>Bilateral femoral hernia is extremely rare in children. The diagnosis is challenging, and it often requires multiple surgeries before the correct treatment can be provided. In this case report, a five-year-old boy had two surgeries on suspicion of a right-sided inguinal hernia, but no hernia was found. After the second operation, the suspicion of a hernia was still present. This led to a diagnostic laparoscopy, where a bilateral femoral hernia was found. Laparoscopic McVay procedure was performed on both sides with minor modifications, which consisted of hernia sac plication and fixation to fortify the abdominal wall.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Louise Elkjær Fløe, Astrid Næraa Høeg Vendelsøe, Lars Henrik Jensen, Mette Stie, Peter Hjorth, Jens Søndergaard, Anna Mygind, Poul Videbech, Jesper Grau Eriksen, Terese Myhre Bentson, Josefine Maria Bruun, Søren Paaske Johnsen, Mette Asbjørn Neergaard
{"title":"Patients with cancer and pre-existing severe mental disorder.","authors":"Louise Elkjær Fløe, Astrid Næraa Høeg Vendelsøe, Lars Henrik Jensen, Mette Stie, Peter Hjorth, Jens Søndergaard, Anna Mygind, Poul Videbech, Jesper Grau Eriksen, Terese Myhre Bentson, Josefine Maria Bruun, Søren Paaske Johnsen, Mette Asbjørn Neergaard","doi":"10.61409/V09230604","DOIUrl":"https://doi.org/10.61409/V09230604","url":null,"abstract":"<p><p>Patients with cancer and pre-existing severe mental disorder, which include moderate to severe depression, bipolar disorder and schizophrenia, are known to have reduced life expectancy and are less likely to get recommended cancer treatment. Barriers at patient-, provider- and system level have been identified, e.g. lack of identification of psychiatric comorbidity, shortage of stabilising psychiatric symptoms and fragmentation of the healthcare system. Patient-centered, interdisciplinary and cross-sectorial healthcare interventions have shown a high potential to improve the cancer care, as argued in this review.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiac involvement in eosinophilic granulomatosis with polyangiitis.","authors":"Michella Dinithi Peiris, Lotte Saaby, Keld-Erik Byg","doi":"10.61409/V02240141","DOIUrl":"https://doi.org/10.61409/V02240141","url":null,"abstract":"<p><p>This case report describes a 40-year-old male patient with severe cardiac failure due to eosinophilic granulomatosis with polyangiitis (EGPA) and myocarditis. The fast diagnostic approach with cardiac MRI (CMR) and immunosuppressive treatment with glucocorticoid and cyclophosphamide near-normalized the patient's cardiac function. Myocarditis due to EGPA is rare, however life-threatening, so a systematic approach and early CMR should be considered in patients with known asthma presenting with eosinophilia and cardiac involvement.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jakob Mejdahl Bentin, Lars Arendt-Nielsen, Asger Reinstrup Bihlet
{"title":"Placebo effect in clinical practice.","authors":"Jakob Mejdahl Bentin, Lars Arendt-Nielsen, Asger Reinstrup Bihlet","doi":"10.61409/V02240121","DOIUrl":"10.61409/V02240121","url":null,"abstract":"<p><p>The term placebo poses challenges in definition, language and use in research and clinical settings. Placebo extends beyond inactive substances, and modern exploration has revealed complex neurobiological, psychological, and social factors influencing placebo mechanisms. With knowledge of the placebo effect, clinicians can assess and enhance the effectiveness of the most optimal treatments. Future research should explore ethical ways of promoting placebo effects, aligning with broader goals in medical practice, as argued in this review.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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