Emilie Grønlund, Lærke Lund, Tina Vilsbøll, Sofie Hædersdal
{"title":"Modern insulin treatment for type 2 diabetes.","authors":"Emilie Grønlund, Lærke Lund, Tina Vilsbøll, Sofie Hædersdal","doi":"10.61409/V03240172","DOIUrl":"https://doi.org/10.61409/V03240172","url":null,"abstract":"<p><p>This review summarises the current and possible future insulin treatment of type 2 diabetes. The type 2 diabetes treatment guidelines prioritise a person-centred approach with various options before insulin addressing cardiorenal protection. Long-acting daily insulin injections are warranted in severe hyperglycaemia or when glycaemic targets are not met. Insulin, when possible, should be combined with other agents to lower insulin dosage, weight gain and hypoglycaemia. Once-weekly insulin offers a promising treatment, reducing injection burden, enhancing treatment satisfaction, and lowering the risk of severe hypoglycaemia, potentially improving type 2 diabetes management.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefan Cobanovic, Daniel Kondziella, Lasse Wille, Steven Haugbøl
{"title":"Ischaemic apoplexy caused by syphilis.","authors":"Stefan Cobanovic, Daniel Kondziella, Lasse Wille, Steven Haugbøl","doi":"10.61409/V01240040","DOIUrl":"https://doi.org/10.61409/V01240040","url":null,"abstract":"<p><p>Syphilis is a sexually transmitted disease caused by the spirochaete Treponema pallidum. Patients with untreated syphilis can develop meningovascular syphilis at any stage of the disease. This is a case report of a 44-year-old man displaying two instances of acute vertigo and lateralized paraesthesia. MRI showed infarctions in the left thalamus and capsula interna. Subsequent investigations including cerebral spinal fluid analysis revealed a diagnosis of neurosyphilis. The patient was treated intravenously with benzylpenicillin and ceftriaxone with complete clinical remission.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anne Gerdes, Iben Fasterholdt, Benjamin Sb Rasmussen
{"title":"AI ethics in healthcare.","authors":"Anne Gerdes, Iben Fasterholdt, Benjamin Sb Rasmussen","doi":"10.61409/V09230600","DOIUrl":"https://doi.org/10.61409/V09230600","url":null,"abstract":"<p><p>Artificial Intelligence (AI) holds promise in improving diagnostics and treatment. Likewise, AI is anticipated to mitigate the impacts of staff shortages in the healthcare sector. However, realising the expectations placed on AI requires a substantial effort involving patients and clinical domain experts. Against this setting, this review examines ethical challenges related to the development and implementation of AI in healthcare. Furthermore, we introduce and discuss various approaches, guidelines, and standards that proactively aim to address ethical challenges.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Kønsfordelingen blandt korresponderende forfattere i Ugeskrift for Læger – rimelig med plads til forbedring.","authors":"Thomas Benfield","doi":"10.61409/V205188","DOIUrl":"https://doi.org/10.61409/V205188","url":null,"abstract":"","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lotte Ørneborg Rodkjær, Pernille Skovlund, Jeanette Finderup, Anne Poder Petersen, Anne Wilhøft Kristensen, Bente Skovsby Toft, Gitte Susanne Rasmussen, Louise Engelbrecht Buur, Nanna Rolving, Tina Wang Vedelø, Annesofie Lunde Jensen
{"title":"Involvement of patients in the research process.","authors":"Lotte Ørneborg Rodkjær, Pernille Skovlund, Jeanette Finderup, Anne Poder Petersen, Anne Wilhøft Kristensen, Bente Skovsby Toft, Gitte Susanne Rasmussen, Louise Engelbrecht Buur, Nanna Rolving, Tina Wang Vedelø, Annesofie Lunde Jensen","doi":"10.61409/V10230668","DOIUrl":"https://doi.org/10.61409/V10230668","url":null,"abstract":"<p><p>Healthcare research emphasises involvement of patients in the research process, recognizing that this can enhance the relevance, quality, and implementation of research. This article highlights the need for more systematic planning to successfully involve patients in research projects and provides guidance on key aspects that researchers should consider in the planning of involving patients in research. The article accentuates the importance of establishing clear frameworks and guidelines to promote transparency and facilitate implementation.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sofie Willemoes Carstensen, Kenn Dornonville de la Cour, Paul Peterslund
{"title":"Familial accumulation of death associated with general anaesthesia.","authors":"Sofie Willemoes Carstensen, Kenn Dornonville de la Cour, Paul Peterslund","doi":"10.61409/V01240044","DOIUrl":"10.61409/V01240044","url":null,"abstract":"<p><p>This is a case report of a 66-year-old male patient with spinocerebellar ataxia type 1 and a family history of anaesthesia-related death was anaesthetised with total intravenous anaesthesia and neuromuscular blockade for laparoscopic cholecystectomy. Anaesthesia and surgery were uneventful. In the post-anesthesia care unit, the patient developed acute respiratory distress and was admitted to the intensive care unit (ICU) for mechanical ventilation. He recovered respiratorically and was released from the ICU after four days. Risks associated with anaesthesia in patients with neurodegenerative disorders should be considered before performing surgery.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kaziwa B Rasoul, Lennart Friis-Hansen, Christian Bjørn Poulsen
{"title":"Smudge cells.","authors":"Kaziwa B Rasoul, Lennart Friis-Hansen, Christian Bjørn Poulsen","doi":"10.61409/V11230714","DOIUrl":"https://doi.org/10.61409/V11230714","url":null,"abstract":"<p><p>Smudge cells can be defined as ruptured or destroyed cells - most commonly lymphocytes where cytoplasm and nuclei get smudged during smear test of the patient's blood/preparation of slides. When finding smudge cells, it is recommended to control the lab work frequently. If a persistent or higher number of smudge cells are found during 3 months, it should lead to a referral to the hematologist. The purpose of this review is to give an overview of smudge cells and conditions in which they can be found, as well as management of the findings.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sille Brændsgaard Nørfjand, Christina Aarenstrup Daugaard, Mette Søndergaard Deleuran
{"title":"Syphilis.","authors":"Sille Brændsgaard Nørfjand, Christina Aarenstrup Daugaard, Mette Søndergaard Deleuran","doi":"10.61409/V01240049","DOIUrl":"10.61409/V01240049","url":null,"abstract":"<p><p>This is a case report of 51-year-old male patient with various symptoms including skin rashes, sensory disturbances, and non-cicatricial hair loss. Despite previous tests, the cause remained elusive until a dermatological examination revealed signs of syphilis. The patient's history, including his sexual relationships, became key in confirming the diagnosis, leading to treatment for neurosyphilis. With a rising incidence of syphilis in Denmark, this case highlights the importance of considering syphilis as a potential diagnosis across medical specialities because of the diverse and challenging clinical manifestations.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martine Siw Nielsen, Maria Bisgaard Borup, Jens Kjeldsen, Michael Stenger, Anders Rørbæk Madsen, Henrik Schmidt, Torkell Ellingsen, Jesper Rømhild Davidsen
{"title":"Cough-induced laryngeal oedema requiring ventilator.","authors":"Martine Siw Nielsen, Maria Bisgaard Borup, Jens Kjeldsen, Michael Stenger, Anders Rørbæk Madsen, Henrik Schmidt, Torkell Ellingsen, Jesper Rømhild Davidsen","doi":"10.61409/V12230792","DOIUrl":"10.61409/V12230792","url":null,"abstract":"<p><p>This case report describes laryngeal oedema occurring in a 35-year-old woman with chronic bowel-associated dermatosis-arthritis syndrome, and stenosis of the left main bronchus. The oedema was attributed to persistent cough exacerbated by delayed treatment and intubation-related irritation. Evaluations ruled out inflammatory, autoimmune, and malignant causes. Literature lacks on specific descriptions of cough-induced laryngeal oedema, emphasizing the need for a multidisciplinary approach and early intervention in complex cases to prevent severe hospitalizations in patients with known serious conditions and symptom exacerbation.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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