Gustav Østerlund Larsen, Krista Dybtved Kjærgaard, Christian Daugaard Peters
{"title":"[Difelikefalin for severe chronic kidney disease-associated pruritus in a patient in dialysis].","authors":"Gustav Østerlund Larsen, Krista Dybtved Kjærgaard, Christian Daugaard Peters","doi":"10.61409/V09240621","DOIUrl":"https://doi.org/10.61409/V09240621","url":null,"abstract":"<p><p>In this case report, a 72-year-old male haemodialysis patient with severe chronic kidney disease-associated pruritus (CKD-aP) was given difelikefalin (DFK) 50 μg × 3/week after unsuccessful standard therapy including fatty cream, steroids, antihistamines, gabapentinoids, and UV-light. CKD-aP was verified by a dermatologist before DFK was given. After three weeks, CKD-aP had improved markedly. The worst itch numeric rate scale (range: 0-10) dropped to 0 from 7-8 prior to DFK. DFK caused drowsiness which disappeared when the treatment was paused. DFK dose was then reduced to 25 μg × 3/week which was well tolerated. The skin healed, except for scars caused by scratching.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Torkveret hydrosalpinx som sjælden årsag til akutte mavesmerter.","authors":"Julie Milbak, Anna Aabakke","doi":"10.61409/V72073","DOIUrl":"https://doi.org/10.61409/V72073","url":null,"abstract":"","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ditte Nortov Schreiner, Xiong Xie, Robert Gvozdenovic
{"title":"[The MR scan of triangular fibrocartilaginous complex injuries].","authors":"Ditte Nortov Schreiner, Xiong Xie, Robert Gvozdenovic","doi":"10.61409/V05240362","DOIUrl":"https://doi.org/10.61409/V05240362","url":null,"abstract":"<p><p>This review examines whether MRI can reliably replace wrist arthroscopy in diagnosing TFCC injuries of the ulnar wrist, based on 18 articles selected through PubMed, Embase, and Cochrane Library. MRI shows improvement in diagnosing TFCC injuries, and the predictive values of MRI get significantly better by using tools like post-processing techniques, contrast, and pathological markers. However, MRI is unreliable as an independent diagnostic tool for TFCC lesions that need surgical treatment. More well-designed studies are required to determine this diagnostic modality's clinical relevance.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Uroplania and multiple abscesses in the lower extremity after ureteral rupture].","authors":"Lauge Bundvad, Nessn Azawi","doi":"10.61409/V07240460","DOIUrl":"https://doi.org/10.61409/V07240460","url":null,"abstract":"<p><p>This is a case report of non-traumatic ureteral rupture caused by a 12-mm obstructing ureteral stone. A male patient in the mid-50's developed uroplania and multiple abscesses in the left lower extremity. To treat the infection, he underwent multiple procedures alternately at urological and orthopaedic departments. Ureteral rupture is a potentially dangerous disorder that therefore requires accelerated diagnostics and often a multidisciplinary treatment.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Gastric volvulus].","authors":"Katrin Manzenreiter, Mette Astrup Tolver","doi":"10.61409/V03240233","DOIUrl":"https://doi.org/10.61409/V03240233","url":null,"abstract":"<p><p>Gastric volvulus is a condition that brings diagnostically difficulties due to various symptoms. It can be an easily missed diagnosis, which can have severe consequences in acute cases with gastric necrosis, perforation, and sepsis. The gold standard for diagnosis and treatment is a CT scan followed by surgical treatment with gastropexy.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[New treatment strategies in assisted reproduction].","authors":"Cecilia Kiehn Myrup, Nathalie Friis Wang, Kristine Løssl, Anja Pinborg","doi":"10.61409/V06240389","DOIUrl":"https://doi.org/10.61409/V06240389","url":null,"abstract":"<p><p>This review elucidates the roles of vitrification and blastocyst culture in assisted reproductive technology. Vitrification exploits ultra-fast cooling rates to preserve embryos and avoid cell-damaging ice crystals. With the cultivation of the embryo to the blastocyst stage, survival- and pregnancy rates are now comparable to those achieved with fresh embryos. This has provided numerous advantages, and this review will focus on the management of ovarian hyperstimulation syndrome, the use of gonadotropin-releasing hormone-agonist trigger, elective single embryo transfer, and preimplantation genetic testing.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Muligheder og udfordringer ved behandling af kronisk insomni.","authors":"Marie Kim Wium-Andersen","doi":"10.61409/V10240729","DOIUrl":"https://doi.org/10.61409/V10240729","url":null,"abstract":"","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Urinary incontinence cured by inguinoscrotal hernia operation].","authors":"Binyamin Sikander, Lars Lund, Jacob Rosenberg","doi":"10.61409/V05240310","DOIUrl":"https://doi.org/10.61409/V05240310","url":null,"abstract":"<p><p>This case report is about an atypical incarcerated right-sided inguinoscrotal hernia with bladder involvement and secondary urinary incontinence in a male in his mid-70s. The patient had no lower urinary tract symptoms but underwent a herniotomy, revealing bladder involvement. Post-surgery showed no signs of urinary incontinence, and most probably bladder distortion caused continuous urine seepage. Inguinoscrotal hernias with bladder involvement are rare and usually asymptomatic. CT scans can diagnose bladder involvement preoperatively.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Cognitive behavioural therapy for chronic insomnia].","authors":"Ellen Berggreen Jochumsen, Anne Mette Kelstrup","doi":"10.61409/V06240390","DOIUrl":"https://doi.org/10.61409/V06240390","url":null,"abstract":"<p><p>Chronic insomnia is a frequently occurring problem, and the number of Danes who experience sleep problems is increasing. Cognitive behavioural therapy for insomnia (CBT-i) as argued in this review is recommended as the first choice of treatment either face-to-face or digitally. Pharmacological treatment should only be used if CBT-i is not sufficient. The effect of CBT-i has been investigated in several meta-analyses and systematic reviews, the effect is found to be good and the recommendation for using CBT-i is strong. Digital CBT-i programs have been developed, and here the efficacy is also found to be good.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Malignant tumour from a ceruminous adenoma in the ear canal].","authors":"Joachim Aidt Becker, Søren Foghsgaard","doi":"10.61409/V10240715","DOIUrl":"https://doi.org/10.61409/V10240715","url":null,"abstract":"<p><p>In this case report, a 77-year-old man presented in 2016 with a tumour in the ear canal. A biopsy revealed a benign ceruminous adenoma, which was surgically removed. The tumour recurred in 2019 and 2022, with each recurrence surgically removed and confirmed as benign. In December 2023, the patient developed facial paralysis and diagnostic imaging showed an infiltrating tumour. A biopsy revealed an exceedingly rare malignant ceruminous adenocarcinoma. The tumour was deemed inoperable and the patient was referred to radiotherapy. Prior biopsies were re-evaluated and were shown to be identical to the 2023 malignancy.</p>","PeriodicalId":23428,"journal":{"name":"Ugeskrift for laeger","volume":"187 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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