Turkish Journal of Ophthalmology最新文献

{"title":"Out of Sight, Out of Chamber: PreserFlo^® MicroShunt Dislocation Following Office-Based Needling.","authors":"Rocío García-Risco, Tetiana Goncharova Simón, Marc Tort, Paula Garcia Valentin, Cristina Parés Alfonso, Paul Gerard Buck Espel, Laura Sánchez Vela, Marta Castany","doi":"10.4274/tjo.galenos.2026.47808","DOIUrl":"10.4274/tjo.galenos.2026.47808","url":null,"abstract":"","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"56 3","pages":"203-207"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148319189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refractive and Visual Outcomes in Unilateral Duane Retraction Syndrome: Influence of Ocular Motility.","authors":"Barbaros Hayrettin Ünlü, Özlem Ural Fatihoğlu, Ceren Durmaz Engin, Aylin Yaman, Ayşe Tülin Berk","doi":"10.4274/tjo.galenos.2026.79815","DOIUrl":"10.4274/tjo.galenos.2026.79815","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the refractive profiles and clinical characteristics of affected and fellow eyes in unilateral Duane retraction syndrome (DRS), emphasize subtype-related variations, and assess the impact of motility restriction and ocular findings on refractive status.</p><p><strong>Materials and methods: </strong>This retrospective cross-sectional study included 191 patients with unilateral DRS, comprising type I (n=162), type II (n=7), and type III (n=22). Best-corrected visual acuity (BCVA), cycloplegic autorefraction, astigmatism classification, and ocular alignment/motility findings were analyzed across DRS subtypes.</p><p><strong>Results: </strong>The mean age at examination was 6.67±7.13 years, and 62.3% of the patients were female. Amblyopia was observed in 23.0% of patients, anisometropia in 18.6%, and abnormal head posture in 52.7% of patients. Esotropia (42.0%) was more prevalent than exotropia (11.7%), and the majority of patients (61.4%) exhibited grade 4 horizontal limitation. Compared with fellow eyes, DRS eyes exhibited a substantially lower BCVA (p<0.001), higher spherical power (p=0.025), and greater cylindrical power (p<0.001). In both DRS (60.7%) and non-DRS (72.3%) eyes, the predominant pattern was with-the-rule astigmatism. There were no discernible variations in astigmatism subtypes among motility limitation grades or DRS subtypes. The cylindrical refractive error was independently associated with abnormal head posture (p=0.007) and horizontal deviation type (p=0.029) according to multiple regression analysis.</p><p><strong>Conclusion: </strong>Unilateral DRS is characterized by diminished visual function and increased refractive error, with cylindrical outcomes affected by head posture and type of deviation. The findings highlight the importance of integrating motility parameters into refractive evaluation and surgical planning in DRS.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"56 3","pages":"158-165"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of the Non-Invasive Tear Break-Up Time Cut-Off Point for Diagnosis of Dry Eye Disease and Its Correlation with Other Dry Eye Tests.","authors":"Ece Yalçındağ, Ziya Akıngöl, Elif Bağatur Vurgun, Semra Akkaya Turhan, Ebru Toker","doi":"10.4274/tjo.galenos.2026.99690","DOIUrl":"10.4274/tjo.galenos.2026.99690","url":null,"abstract":"<p><strong>Objectives: </strong>To determine optimal cut-off values for first and average non-invasive tear break-up time (NIBUT-f and NIBUT-av, respectively) in dry eye disease (DED), as well as evaluate their correlation with other tests.</p><p><strong>Materials and methods: </strong>This retrospective study included 46 patients with DED and 35 healthy controls. All subjects were assessed using the Ocular Surface Disease Index questionnaire. NIBUT measurements and meibography images were obtained using the Sirius topography device. The conventional diagnostic tests Schirmer-I, tear break-up time (TBUT), ocular surface staining (OSS), Marx line score, and lid wiper epitheliopathy (LWE) grade were performed.</p><p><strong>Results: </strong>The cut-off values of NIBUT-f and NIBUT-av for DED diagnosis were identified as 10.7 and 12.2 seconds, respectively. The area under the curve (AUC) was 0.93 (95% confidence interval [CI]: 0.889-0.992) for NIBUT-f and 0.92 (95% CI: 0.872-0.985) for NIBUT-av. For the differentiation between evaporative and mixed DED subtypes, the NIBUT-av cut-off value was 7.2 seconds, with an AUC of 0.63 (95% CI: 0.512-0.743). NIBUT-av showed a positive correlation with TBUT (p<0.001, r=0.905) and Schirmer-I (p<0.001, r=0.403) but a negative correlation with OSS (p<0.001, r=-0.700), meibomian gland loss (p<0.001, r=-0.601), LWE grade (p<0.001, r=-0.597), and Marx line score (p<0.001, r=-0.539).</p><p><strong>Conclusion: </strong>NIBUT is a highly sensitive and specific non-invasive diagnostic tool for DED that correlates with other ocular surface and meibomian gland function tests.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"56 3","pages":"148-157"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Dietary Nutritional Profile in Turkish Patients with Age-Related Macular Degeneration.","authors":"Bengi Demirayak, Erdinç Bozkurt, Hatice Nur Tarakçıoğlu, Tuğba Aydoğan Gezginaslan, Murat Karapapak, Sadık Altan Özal, Özen Ayrancı Osmanbaşoğlu, Sezin Özdoğan Erku, Mehmet Erdoğan, Nihat Sayın, Mine Öztürk, Abdullah Ağın, Tahsin Uzundede, Akın Çakır, Abdullah Özkaya","doi":"10.4274/tjo.galenos.2026.26641","DOIUrl":"10.4274/tjo.galenos.2026.26641","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the dietary nutritional profile according to the suggestions of the Age-Related Eye Disease Study 2 (AREDS2) in Turkish patients with age-related macular degeneration (AMD).</p><p><strong>Materials and methods: </strong>The study included patients diagnosed with non-neovascular AMD in one or both eyes and who underwent routine follow-up in retina clinics at tertiary centers in İstanbul between May 12 and May 27, 2025. An ocular nutrition questionnaire prepared according to AREDS2 suggestions was translated into Turkish. The survey was conducted among our cohort after its reproducibility and validity were confirmed. Consumption of fish-shellfish, hazelnut-walnut-peanut, eggs, leafy greens, red pepper, carrot-pumpkin, and peppers-green tea-strawberry-citrus (eicosapentaenoic acid, docosahexaenoic acid, omega 3, lutein, zeaxanthin, beta-carotene, and antioxidant-rich foods, respectively), micronutrient supplementation, smoking, physical activity, anxiety about vision loss, education level, and monthly income were recorded.</p><p><strong>Results: </strong>A total of 530 patients from 7 clinics who answered all questions were evaluated. Adequate consumption of omega-3-rich foods consumption was reported by 19.3% of participants, whereas 57.2% reported no fish intake in the last week. Adequate consumption of foods rich in lutein/zeaxanthin, beta-carotene, and antioxidants was reported by 63.6%, 41.7%, and 4.7% of patients, respectively, and regular micronutrient supplementation was reported by 35.5%. Of the patients, 23.6% reported high anxiety about vision loss, 69.8% reported elementary or lower education, and 64.9% had a 20,000 TRY or lower monthly income. Micronutrient intake was positively associated with anxiety (p=0.0001) and education (p=0.02) but not with monthly income (p=0.1).</p><p><strong>Conclusion: </strong>According to this first report in Turkish patients with AMD which was evaluated nutrition profile based on AREDS2 suggestions, patients showed low adherence to AREDS recommendations for micronutrient intake and lifestyle modifications. Awareness among patients and ophthalmologists needs improvement.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"56 3","pages":"180-186"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148319208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modification of the Temporal Inverted Internal Limiting Membrane Flap in Macular Hole Surgery: Envelope Technique","authors":"Sinan Tatlıpınar","doi":"10.4274/tjo.galenos.2026.20269","DOIUrl":"10.4274/tjo.galenos.2026.20269","url":null,"abstract":"<p><p>This case report aims to present a modification of the temporal inverted internal limiting membrane (ILM) flap technique in macular hole surgery. The inverted ILM flap technique was first described in 2010 and was shown to yield superior functional and anatomical outcomes in large macular holes compared to traditional ILM peeling. However, flap displacement can be a major concern with the inverted ILM flap technique. In the first case, a failed large macular hole after temporal inverted ILM flap surgery was reoperated, and flap displacement was observed as the reason for failure. The displaced ILM flap was inverted again and the superior corner of the flap was tucked under the small ILM defect in the upper nasal macular area to stabilize it. Hence, it is called as “envelope modification”. Another patient with rhegmatogenous retinal detachment with coexistent macular hole underwent vitrectomy surgery with silicone oil. The retina was attached postoperatively, and the macular hole was closed with a flat-open pattern. During silicone oil removal, the envelope modification was used and the hole closed. Both patients had visual improvement. Although the inverted ILM flap technique is very effective for large macular holes, the modification described here may further improve the success rate.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":" ","pages":"198-202"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148139006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional or Dysfunctional Epiphora? A Reminder for Refined Terminology","authors":"Bülent Yazıcı, Meryem Altın Ekin","doi":"10.4274/tjo.galenos.2026.77378","DOIUrl":"10.4274/tjo.galenos.2026.77378","url":null,"abstract":"","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":" ","pages":"72-73"},"PeriodicalIF":0.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13112508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply.","authors":"Murat Erbezci, Zühal Özen Tunay, Taylan Öztürk","doi":"10.4274/tjo.galenos.2026.45837","DOIUrl":"10.4274/tjo.galenos.2026.45837","url":null,"abstract":"","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"56 2","pages":"146-147"},"PeriodicalIF":0.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13112500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Syphilitic Uveitis in HIV-Positive and -Negative Patients: A Multicenter Cohort Study.","authors":"Kübra Özdemir Yalçınsoy, Murat Oklar, Merve İnanç Tekin, Hilal Eser-Öztürk, Sedat Özmen, Nilüfer Zorlutuna Kaymak, Burak Tanyıldız, Pınar Çakar Özdal","doi":"10.4274/tjo.galenos.2026.39267","DOIUrl":"10.4274/tjo.galenos.2026.39267","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the clinical manifestations and visual outcomes of patients with syphilitic uveitis, and to compare these features based on human immunodeficiency virus (HIV) infection status.</p><p><strong>Materials and methods: </strong>The records of patients diagnosed with syphilitic uveitis between 2014 and 2024 were analyzed retrospectively. Demographics, history, ocular examination findings, syphilis and HIV serology, lumbar puncture test, treatment approaches, and best-corrected visual acuity (BCVA) results of all patients were documented.</p><p><strong>Results: </strong>A total of 51 eyes of 33 patients were included in the study. Twenty-seven patients (82%) were male, with a mean age of 44 years (range, 21-69). HIV co-infection was present in 39% of the patients (all male). Prior to presentation, 9 patients (27%) had received an incorrect diagnosis or inappropriate treatment. The most common form of syphilitic uveitis was panuveitis (63%), followed by posterior uveitis (31%). Anterior segment inflammation and optic nerve involvement were observed at higher rates in patients with HIV co-infection (p<0.05). All patients received systemic penicillin therapy, and 51% received systemic corticosteroids. Visual acuity improved significantly after treatment in all patients (p<0.01). HIV co-infection status was not associated with age, laterality, lumbar puncture findings, the development of ocular complications, or baseline and final BCVA outcomes (p>0.05).</p><p><strong>Conclusion: </strong>Syphilitic uveitis is an important clinical entity due to its broad spectrum of ocular manifestations. In this study, severe intraocular inflammatory findings, including panuveitis and optic nerve involvement, were more frequently observed in patients with HIV co-infection. However, HIV co-infection did not influence final visual acuity or the rate of ocular complication development.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"56 2","pages":"98-109"},"PeriodicalIF":0.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13112509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor Re: Preferred Retinal Locus in Juvenile Macular Dystrophy.","authors":"Shyam Sundar Sah, Abhishek Kumbhalwar","doi":"10.4274/tjo.galenos.2026.65259","DOIUrl":"10.4274/tjo.galenos.2026.65259","url":null,"abstract":"","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"56 2","pages":"145-146"},"PeriodicalIF":0.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13112511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suture Revision for the Management of Postoperative Intraocular Pressure Spike Following Cyclodialysis Repair in Chronic Five-Year Hypotony.","authors":"Ali Mert Koçer, Bekir Eren Aksoy","doi":"10.4274/tjo.galenos.2026.35559","DOIUrl":"10.4274/tjo.galenos.2026.35559","url":null,"abstract":"","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"56 2","pages":"131-134"},"PeriodicalIF":0.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13112502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}