Turkish Journal of Ophthalmology最新文献_第2页

Unilateral Papilledema with Bilateral Optic Nerve Sheath Distension: A Case Report. 单侧乳头水肿伴双侧视神经鞘扩张：病例报告

Turkish Journal of Ophthalmology Pub Date : 2024-08-28 DOI: 10.4274/tjo.galenos.2024.87243

Raghda Shawky El-Gendy, Ahmad Shehata Abd El-Hamid, Ayman El-Sayed Ali Galhom, Nihal Adel Hassan, Ehab Mahmoud Ghoneim

引用次数: 0

Multimodal Imaging Characteristics and Diagnostic Value of Choroidal Nodules in Patients with Neurofibromatosis Type 1. 神经纤维瘤病 1 型患者脉络膜结节的多模态成像特征和诊断价值。

Turkish Journal of Ophthalmology Pub Date : 2024-06-28 DOI: 10.4274/tjo.galenos.2024.48017

Nargiz Ahmadova, Mustafa Kayabaşı, Seher Köksaldı, Eda Hümaz, Ali Osman Saatci

{"title":"Multimodal Imaging Characteristics and Diagnostic Value of Choroidal Nodules in Patients with Neurofibromatosis Type 1.","authors":"Nargiz Ahmadova, Mustafa Kayabaşı, Seher Köksaldı, Eda Hümaz, Ali Osman Saatci","doi":"10.4274/tjo.galenos.2024.48017","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2024.48017","url":null,"abstract":"Objectives: Yasunari nodules are choroidal lesions observed in patients diagnosed with neurofibromatosis type 1 (NF-1) and characterized by relatively irregular dome-shaped, plaque-like, or patchy boundaries. The present study examines the multimodal imaging characteristics of Yasunari nodules and their value in the diagnosis of NF-1.Materials and methods: Medical records including optical coherence tomography (OCT), enhanced depth imaging OCT, infrared reflectance (IR) imaging, OCT angiography, and color fundus images of NF-1 patients who were examined at the Department of Ophthalmology in Dokuz Eylül University Faculty of Medicine between January 2022 and December 2023 were retrospectively reviewed for the presence of Yasunari nodules.Results: A total of 54 eyes of 27 patients were included in the study. At least one choroidal nodule was detected on IR imaging in 52 eyes (96.3%). In 31 (72.1%) of the 43 eyes (79.6%) with available high-quality OCT angiography images, choroidal nodules were observed as areas showing a flow deficit in the choriocapillaris layer. Of the total 54 eyes included, Lisch nodules without choroidal nodules were observed in 2 eyes (3.7%). In 16 eyes (29.6%), Lisch nodules were not detected despite the presence of choroidal nodules. Both Lisch nodules and choroidal nodules were detected in the other 36 eyes (66.7%).Conclusion: Yasunari nodules are frequently observed in NF-1 cases and can be easily detected with multimodal imaging techniques, especially IR imaging. The ability to visualize choroidal nodules before the appearance of Lisch nodules demonstrates the importance of Yasunari nodules in the diagnosis of NF-1.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ocular Manifestations of Fabry Disease: Report from a Tertiary Eye Care Center in Türkiye. 法布里病的眼部表现：来自土耳其一家三级眼科中心的报告。

Turkish Journal of Ophthalmology Pub Date : 2024-06-28 DOI: 10.4274/tjo.galenos.2024.09482

İlayda Korkmaz, Sema Kalkan Uçar, Hüseyin Onay, Eser Yıldırım Sözmen, Mahmut Çoker, Melis Palamar

{"title":"Ocular Manifestations of Fabry Disease: Report from a Tertiary Eye Care Center in Türkiye.","authors":"İlayda Korkmaz, Sema Kalkan Uçar, Hüseyin Onay, Eser Yıldırım Sözmen, Mahmut Çoker, Melis Palamar","doi":"10.4274/tjo.galenos.2024.09482","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2024.09482","url":null,"abstract":"Objectives: To report ocular manifestations in patients with Fabry disease (FD) from a tertiary eye care center in Türkiye.Materials and methods: This prospective, cross-sectional study included 30 eyes of 15 patients with FD. The diagnosis of FD was made based on a combination of clinical findings, genetic analysis, and biochemical evaluation. All participants underwent a detailed ophthalmic examination with special focus on the typical ocular features of FD (cornea verticillata, conjunctival aneurysms, cataract, retinal vessel tortuosity).Results: The mean age was 45±17 years (range: 22-75 years), with a female/male ratio of 2:3. All patients had tortuous conjunctival vessels and 12 patients (80%) had conjunctival aneurysms. Cornea verticillata was present in 10 patients (66.6%), lens opacification in 4 patients (26.6%), and retinal vascular tortuosity in 8 patients (53.3%). All patients had at least two different ocular findings; most (3 heterozygotes/7 hemizygotes) had a combination of corneal verticillata and conjunctival vessel abnormality. The conjunctiva, cornea, and retina were affected together in 5 hemizygous patients (33.3%). One hemizygous patient had all FDrelated ocular manifestations in both eyes.Conclusion: To our knowledge, this study is the first to describe the ocular manifestations of FD in the Turkish population. Although cornea verticillata is considered a hallmark of FD, it was absent in approximately one-third of patients. Moreover, cataract, another well-known feature of FD, was present in only 26.6% of the patients. Conjunctival vascular abnormality alone seems to be quite rare in FD, although it often accompanies other ocular manifestations. Therefore, recognition of other mild findings and special consideration of their associations may increase the diagnostic value of ocular findings in FD.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orbital Cerebrospinal Fluid Leak After Dog Bite: A Case Report 被狗咬伤后眼眶脑脊液漏：病例报告。

Turkish Journal of Ophthalmology Pub Date : 2024-06-28 Epub Date: 2024-05-31 DOI: 10.4274/tjo.galenos.2024.45087

Bilal Bahadır Akbulut, Elif Bolat

引用次数: 0

Could Triglyceride-Glucose Index, a Predictor of Atherosclerosis, Be Associated with Retinal Vein Occlusion? 作为动脉粥样硬化预测指标的甘油三酯-葡萄糖指数是否与视网膜静脉闭塞有关？

Turkish Journal of Ophthalmology Pub Date : 2024-06-28 DOI: 10.4274/tjo.galenos.2024.69841

Zeynep Katipoğlu, Meydan Turan

{"title":"Could Triglyceride-Glucose Index, a Predictor of Atherosclerosis, Be Associated with Retinal Vein Occlusion?","authors":"Zeynep Katipoğlu, Meydan Turan","doi":"10.4274/tjo.galenos.2024.69841","DOIUrl":"10.4274/tjo.galenos.2024.69841","url":null,"abstract":"Objectives: The triglyceride-glucose (TyG) index is a sign of atherosclerosis in cardiovascular diseases. The TyG index is thought to have clinical significance for the assessment of vascular damage. In this study we aimed to demonstrate the connection between the TyG index and retinal vein occlusion (RVO).Materials and methods: This case-control observational study involved 492 participants aged 40-90, admitted to the ophthalmology outpatient clinic of our hospital. TyG index was calculated using the formula: ln(fasting TG [mg/dL] × fasting plasma glucose [mg/dL]/2).Results: The RVO group included 387 patients (181 women and 206 men) and the control group included 115 patients (61 women and 54 men). The average patient age was 62.9±11.1 years in the RVO group and 56.7±8.7 years in the control group. The TyG index was higher in the RVO group (8.9±0.7) than in the control group (8.8±0.6). This difference was statistically significant (p=0.04). The correlation was statistically significant when evaluated according to age and sex by multivariate logistic regression analysis (odds ratio: 1.45, confidence interval: 1.03- 2.02, p=0.03).Conclusion: The TyG index is a novel atherogenicity index that is derived from routine blood tests and can be used to determine the risk of RVO in at-risk individuals with a simple calculation. Therefore, the TyG index could help as a reliable guide to identify individuals at RVO with high risk and initiate early intervention.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Presentation of Carotid-Cavernous Fistula and Outcomes of Endovascular Balloon Embolization 颈动脉海绵瘘的临床表现和血管内球囊栓塞术的疗效

Turkish Journal of Ophthalmology Pub Date : 2024-06-28 Epub Date: 2024-06-10 DOI: 10.4274/tjo.galenos.2024.32457

Tayyaba Gul Malik, Muhammad Moin

{"title":"Clinical Presentation of Carotid-Cavernous Fistula and Outcomes of Endovascular Balloon Embolization","authors":"Tayyaba Gul Malik, Muhammad Moin","doi":"10.4274/tjo.galenos.2024.32457","DOIUrl":"10.4274/tjo.galenos.2024.32457","url":null,"abstract":"Objectives: To describe the clinical presentation of carotico-cavernous fistula (CCF) and outcomes of endovascular balloon embolization in a tertiary care center in a developing country.Materials and methods: This retrospective interventional case series included 18 patients who underwent endovascular balloon embolization from 2019 to 2022 at Lahore General Hospital in Lahore, Pakistan. The analyzed data consisted of age, gender, cause and type of CCF, clinical presentation, diagnostic technique used, intervention, and the results of two-month follow-up. Patients with incomplete records and coil embolization were excluded. Digital subtraction angiography was done in all cases followed by endo-arterial balloon embolization. Procedures were carried out under general anesthesia via femoral artery approach. A single balloon was sufficient to close the fistula in all cases.Results: There were 18 patients who met the inclusion criteria. Sixteen patients had direct CCF, and the mean age of the patients was 27.2±12.6 years. The commonest cause of CCF was trauma, and the mean time of presentation after trauma was 7.89±7.19 months. The male-to-female ratio was 8:1. Preoperative visual acuity was worse than 6/60 in 8 patients, between 6/60 and 6/18 in 7 patients, and better than 6/18 in 3 patients. The mean intraocular pressure was 16.06±3.37 mmHg preoperatively and 14.83±3.49 mmHg postoperatively (p=0.005). Endovascular embolization was successful in 15 patients (83.3%). One patient developed epidural hematoma as a complication of the procedure, which was drained later. There was no mortality related with the procedure.Conclusion: Balloon embolization via the femoral artery is an efficient technique in direct as well as indirect CCF. It is safe and simple with very good results if performed in a timely manner.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endogenous Endophthalmitis Caused by Aspergillus lentulus in an Immunocompromised Patient with Lung Cancer 一名免疫力低下的肺癌患者因曲霉菌引起的内源性眼内炎。

Turkish Journal of Ophthalmology Pub Date : 2024-06-28 Epub Date: 2024-06-11 DOI: 10.4274/tjo.galenos.2024.44045

Mustafa Kayabaşı, Ziya Ayhan, Banu Lebe, Ayşe Aydan Özkütük, Meltem Söylev Bajin, Arzu Nazlı, Eyüp Sabri Uçan, Aziz Karaoğlu, Ali Osman Saatci

{"title":"Endogenous Endophthalmitis Caused by Aspergillus lentulus in an Immunocompromised Patient with Lung Cancer","authors":"Mustafa Kayabaşı, Ziya Ayhan, Banu Lebe, Ayşe Aydan Özkütük, Meltem Söylev Bajin, Arzu Nazlı, Eyüp Sabri Uçan, Aziz Karaoğlu, Ali Osman Saatci","doi":"10.4274/tjo.galenos.2024.44045","DOIUrl":"10.4274/tjo.galenos.2024.44045","url":null,"abstract":"A 78-year-old man with a history of lung cancer, chemotherapy, radiotherapy, and coronavirus disease 2019 infection experienced visual deterioration of two-weeks’ duration in his right eye. There was multifocal, yellowish-white retinitis foci, vascular engorgement, and scattered intraretinal hemorrhages extending from posterior pole to retinal periphery in the right eye, whereas the left eye was normal. Intravitreal vancomycin, ceftazidime, clindamycin, and dexamethasone were given for endogenous endophthalmitis initially. Vitreous culture confirmed the presence of Aspergillus lentulus, and he was treated with intravitreal amphotericin-B and voriconazole injections together with systemic amphotericin-B, voriconazole, posaconazole, and micafungin therapy. During follow-up, vitreoretinal surgery was performed because of rhegmatogenous retinal detachment, and he received one additional cycle of chemotherapy due to recurrence of the cancer. Although the retina was attached, enucleation was eventually required due to painful red eye. Atypical squamous cells beneath the neurosensory retina suggesting metastasis were noted on histopathological examination. Timely ocular examination is crucial for any immunocompromised patient having ocular symptoms. High level of suspicion for a fungal etiology is a must in these patients.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and Safety of the Modified Cretan Protocol in Patients with Post-LASIK Ectasia 改良克里特方案对激光角膜切割术后异位症患者的疗效和安全性。

Turkish Journal of Ophthalmology Pub Date : 2024-06-28 Epub Date: 2024-06-10 DOI: 10.4274/tjo.galenos.2024.82342

Burak Tanrıverdi, Özge Saraç, Berke Temel, Esra Dağ Şeker, Nurullah Çağıl

{"title":"Efficacy and Safety of the Modified Cretan Protocol in Patients with Post-LASIK Ectasia","authors":"Burak Tanrıverdi, Özge Saraç, Berke Temel, Esra Dağ Şeker, Nurullah Çağıl","doi":"10.4274/tjo.galenos.2024.82342","DOIUrl":"10.4274/tjo.galenos.2024.82342","url":null,"abstract":"Objectives: To investigate the clinical efficacy and safety of the modified Cretan protocol in patients with post-laser in situ keratomileusis ectasia (PLE).Materials and methods: In this retrospective study, 26 eyes of 16 patients with PLE were treated with the modified Cretan protocol (combined transepithelial phototherapeutic keratectomy and accelerated corneal collagen cross-linking). Visual, refractive, tomographic, and aberrometric outcomes and point spread function (PSF) were recorded preoperatively and at 6, 12, and 24 months after treatment.Results: Both uncorrected and best corrected visual acuity were stable at 24 months postoperatively compared to baseline (from 0.89±0.36 to 0.79±0.33 logarithm of the minimum angle of resolution [LogMAR] and 0.31±0.25 to 0.24±0.19 LogMAR, respectively, p>0.05 for all values). The mean K1, K2, Kmean, thinnest corneal thickness, and spherical aberration at baseline were 45.76±5.75 diopters (D), 48.62±6.17 D, 47.13±5.89 D, 433.16±56.86 μm, and -0.21±0.63 μm respectively. These values were reduced to 42.86±6.34 D, 45.92±6.74 D, 44.21±6.4 D, 391.07±54.76 μm, and -0.51±0.58 μm at 24 months postoperatively (p<0.001, p=0.002, p<0.001, p=0.001, and p=0.02, respectively). The mean spherical equivalent, manifest cylinder, Kmax, central corneal thickness, other corneal aberrations (root mean square, trefoil, coma, quatrefoil, astigmatism), and PSF remained stable (p>0.05 for all variables), while anterior and posterior elevation were significantly improved at 24 months postoperatively (p<0.001 and p=0.02, respectively). No surgical complications occurred during the 24-month follow-up.Conclusion: The modified Cretan protocol is a safe and effective treatment option for PLE patients that provides visual stabilization and significant improvement in topographic parameters during the 24-month follow-up. Further studies are needed to support our results.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tissue Engineering and Ophthalmology. 组织工程与眼科。

Turkish Journal of Ophthalmology Pub Date : 2024-06-28 DOI: 10.4274/tjo.galenos.2024.49779

Canan Aslı Utine, Sinan Güven

引用次数: 0

The Effect of Conjunctiva-Müller Muscle Resection on Tear Oxidative Stress Levels in Patients with Blepharoptosis 结膜-缪勒肌切除术对眼睑下垂患者泪液氧化应激水平的影响

Turkish Journal of Ophthalmology Pub Date : 2024-06-28 Epub Date: 2024-06-05 DOI: 10.4274/tjo.galenos.2024.02697

Seda Sert, Ceyhun Arıcı, Burak Mergen, Özlem Balcı Ekmekçi

{"title":"The Effect of Conjunctiva-Müller Muscle Resection on Tear Oxidative Stress Levels in Patients with Blepharoptosis","authors":"Seda Sert, Ceyhun Arıcı, Burak Mergen, Özlem Balcı Ekmekçi","doi":"10.4274/tjo.galenos.2024.02697","DOIUrl":"10.4274/tjo.galenos.2024.02697","url":null,"abstract":"Objectives: To examine changes in tear oxidative stress levels and tear film functions in patients with blepharoptosis and dermatochalasis following conjunctiva-Müller muscle resection (CMMR) and blepharoplasty surgeries.Materials and methods: This prospective study included 32 healthy controls and 62 patients with blepharoptosis or dermatochalasis. CMMR surgery was performed in 20 eyes and upper blepharoplasty was performed in 42 eyes. Tear oxidative stress markers (8-hydroxy-2’-deoxyguanosine [8-OHdG] and 4-hydroxy-2-nonenal [4-HNE]) were quantified by enzyme-linked immunosorbent assay and tear film functions were evaluated preoperatively and at 1 and 6 months postoperatively. The same assessments were performed in the control group at the same time points.Results: Preoperative tear 8-OHdG and 4-HNE levels were lower in healthy controls (52.8±13.5 ng/mL and 27.8±6.4 ng/mL, respectively) compared to patients with dermatochalasis (86.1±37.2 ng/mL and 29.8±11.1 ng/mL, respectively) and blepharoptosis (90.4±39.3 ng/mL and 43.1±4.2 ng/mL, respectively) (p<0.001). 8-OHdG levels were increased at 1 month after CMMR, while both markers were decreased 1 month postoperatively in the blepharoplasty group (p=0.034). Schirmer 1 and OSDI scores did not change throughout the visits in both patient groups, but a temporary decrease in tear break-up time (TBUT) was observed after CMMR (p=0.017).Conclusion: Dermatochalasis and blepharoptosis were associated with higher tear oxidative stress levels. CMMR surgery caused a temporary decrease in TBUT scores and an increase in oxidative stress in the first postoperative month.","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0