Turkish Journal of Ophthalmology最新文献

{"title":"Bilateral Keratoconus in Diffuse Cutaneous Systemic Sclerosis: A Rare Presentation - Is There Any Role of Autoimmunity?","authors":"Soumen Sadhu, Bhaskar Srinivasan, Meena Lakshmipathy, Prema Padmanabhan","doi":"10.4274/tjo.galenos.2025.30377","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2025.30377","url":null,"abstract":"","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"55 2","pages":"109-111"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progressive Loss of Myelinated Retinal Nerve Fibers in a Case of Open-Angle Glaucoma.","authors":"Tristan Jurkiewicz, Théo Lereuil, Philippe Germain, Christophe Zech","doi":"10.4274/tjo.galenos.2025.88027","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2025.88027","url":null,"abstract":"<p><p>Myelinated retinal nerve fibers (MRNFs) result from a developmental anomaly in which ectopic oligodendrocytes myelinate retinal ganglion cell fibers. These fibers typically remain stable over time in the absence of pathology. We identified unilateral MRNFs in a patient during an ophthalmological examination associated with ocular hypertension. Over an 8-year follow-up period, we observed a progressive decrease in the retinal nerve fiber layer and a rarefaction of MRNFs, which we attributed to the lack of regular follow-up and treatment compliance. The absence of neuropathy control in this patient makes this description close to the natural evolution of the disease. Similar progressive disappearance of MRNFs has been observed in cases of Behçet's disease, pituitary adenoma, and open-angle glaucoma. In patients with known MRNFs, their disappearance should alert clinicians to potential optic nerve damage and prompt further examinations to determine the underlying cause.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"55 2","pages":"105-108"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of Eye Examination and Vision Screening in Term Infants Presenting to a Tertiary Hospital in Türkiye.","authors":"Nilüfer Zorlutuna Kaymak, Ayşin Tuba Kaplan, Sibel Öskan Yalçın, Raziye Dönmez Gün, Dilber Çelik Yaprak, Burak Tanyıldız","doi":"10.4274/tjo.galenos.2025.07572","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2025.07572","url":null,"abstract":"<p><strong>Objectives: </strong>Ophthalmic screening is an important part of the medical care of children as some eye abnormalities can lead to irreversible vision loss if not treated in the first few months or years of life. The aim of this study is to evaluate the outcomes of the ophthalmic screening program in term infants aged ≤1 year who presented to a tertiary hospital in Türkiye.</p><p><strong>Materials and methods: </strong>The records of 1,035 infants ≤1 year old who underwent ophthalmic screening between November 2019 and February 2022 were reviewed retrospectively. Demographic and medical details, parental complaints about the infants' eyes, family history of ocular, adnexal, and systemic pathologies, light reactions, red reflex test results, eye movements, blink response to light, fixation and following, noticeable strabismus, conjunctivitis, epiphora, anterior segment and fundus pathologies, and treatments applied were recorded. The referring physician (family physician, pediatrician) and reason for reference were also noted.</p><p><strong>Results: </strong>Abnormal ophthalmological findings were detected in 136 infants (13.14%). The most common finding was congenital nasolacrimal duct obstruction (72.05%), followed by strabismus (8.82%), ptosis (4,41%), absence of following (3.67%), congenital cataract (2.94%), hemangioma of the adnexa (2.94%), nystagmus (2.94%), albino fundus (1.47%), preretinal hemorrhage (1.47%), and coloboma of the iris and choroid (1.47%). We detected abnormal red reflex in 4 infants who were not referred for red reflex abnormality by the referring physician, while another 4 infants referred for red reflex abnormality had no pathology on ocular examinations including the red reflex test.</p><p><strong>Conclusion: </strong>The importance of ophthalmic screening in infants is well appreciated but there are inadequacies in performing and interpreting the red reflex test among family physicians and pediatricians. Efforts should be directed at improving vision screening skills, especially red reflex testing.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"55 2","pages":"86-91"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Reasons for Discontinuation of Atropine 0.01% in Myopia Management: A Single-Center Retrospective Study from Türkiye.","authors":"Nilay Akagün, Uğur Emrah Altıparmak","doi":"10.4274/tjo.galenos.2025.86584","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2025.86584","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to identify the key factors contributing to non-adherence in patients using 0.01% atropine for progressive myopia control in a specific single-center Turkish population and to propose strategies to enhance adherence.</p><p><strong>Materials and methods: </strong>This retrospective study included 30 patients (mean age: 10.67±3.47 years; age range: 5-16 years; 14 males and 16 females) diagnosed with progressive myopia and prescribed 0.01% atropine treatment in our clinic between January and June 2021. All participants had discontinued 0.01% atropine treatment before completion. The reasons for discontinuation were analyzed using patient records and categorized into factors such as light sensitivity, difficulties with near vision, ocular or systemic side effects, the need for monthly eye drop renewal, and the long treatment duration. Data on patients' age, sex, treatment adherence, and reasons for discontinuation were collected. Statistical analyses were performed using IBM SPSS Statistics software.</p><p><strong>Results: </strong>The treatment discontinuation rate in our patient population was 14.92% (95% confidence interval: 10.23-19.61). The most common reasons for discontinuation were the need for monthly drop renewal (80%), long treatment duration (70%), and light sensitivity (60%). Discontinuation rates did not significantly differ by age group (p>0.05). The need for monthly renewal was more frequently reported as a barrier among female patients. Informed consent procedures had highlighted the long treatment duration and the need for monthly renewal, but these still represented barriers to adherence for some families.</p><p><strong>Conclusion: </strong>To improve adherence to 0.01% atropine treatment for progressive myopia in our patient population, patient education and enhanced support systems are essential. Implementing strategies to address challenges related to monthly renewal and providing better information about the long-term benefits of treatment could help increase adherence rates.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"55 2","pages":"61-66"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Internal Limiting Membrane Peeling on Anatomical and Visual Outcomes in Patients with Macula-Off Retinal Detachment.","authors":"Deniz Bağcı, Cumali Değirmenci, Filiz Afrashi","doi":"10.4274/tjo.galenos.2025.67847","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2025.67847","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the anatomical and visual outcomes of internal limiting membrane (ILM) peeling in patients with macula-involving (\"macula-off\") retinal detachment treated with silicone oil endotamponade.</p><p><strong>Materials and methods: </strong>The study included 19 eyes of 19 patients (Group 1, ILM peeled) and 33 eyes of 32 patients (Group 2, ILM not peeled) who underwent surgery for macula-off retinal detachment at Ege University Department of Ophthalmology. All patients underwent detailed ophthalmological examination and macular optical coherence tomography preoperatively, at postoperative 1 month, and 1 month after silicone removal.</p><p><strong>Results: </strong>The mean age was 60.47±9.9 years in Group 1 and 57.56±10.63 years in Group 2. The average follow-up duration was 9.13±5.29 months. Preoperative visual acuity was 1.6±1.3 logarithm of the minimum angle of resolution (logMAR) in Group 1 and 1.1±0.8 logMAR in Group 2. At postoperative 1 month, visual acuity was 0.8±0.7 logMAR in Group 1 and 0.7±0.7 logMAR in Group 2 (p=0.1). At 1 month postoperatively, epiretinal membrane (ERM) development was not observed in Group 1, while 9 eyes in Group 2 developed ERM. Visual acuity after silicone removal was similar in both groups (p=0.2). Central foveal thickness (μm) and macular volumes (mm³) were comparable in both groups (p>0.05). Three eyes in Group 2 that developed ERM underwent surgery and their visual acuity improved.</p><p><strong>Conclusion: </strong>ILM peeling during vitreoretinal surgery in cases of macula-off retinal detachment may be effective in preventing ERM formation, though it does not result in significant visual improvement. Further studies with longer follow-up and larger patient cohorts are needed.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"55 2","pages":"82-85"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Humphrey 24-2 SITA Standard, SITA Fast, and SITA Faster Test Strategies in Patients with Glaucoma.","authors":"Seher Köksaldı, Gül Arıkan, Ömer Faruk Dadaş, Üzeyir Günenç","doi":"10.4274/tjo.galenos.2025.85666","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2025.85666","url":null,"abstract":"<p><strong>Objectives: </strong>To compare 24-2 Swedish Interactive Thresholding Algorithm (SITA) Standard (SS), SITA Fast (SF), and SITA Faster (SFR) tests performed with Humphrey Field Analyzer (HFA3 Model 840, Zeiss) in patients with glaucomatous visual field (VF) defect.</p><p><strong>Materials and methods: </strong>Total of 72 eyes of 72 patients with glaucomatous VF defects were included in the study. Test duration, mean deviation (MD), pattern standard deviation (PSD), visual field index (VFI), and the width and depth of glaucomatous VF defect were compared among the three tests.</p><p><strong>Results: </strong>The most common diagnoses were primary open-angle glaucoma in 45 eyes (62.5%) and pseudoexfoliation glaucoma in 10 eyes (13.9%). Mean test durations for the SS, SF, and SFR tests were 420.38±53.87 s, 275.94±45.52 s, and 191.89±35.48 s, respectively. Test durations were found to be statistically significantly different in all three tests (p<0.001). There was no statistically significant difference between the three tests in terms of MD, width, or depth of glaucomatous VF defect (p=0.211, p=0.762, and p=0.701, respectively). There was a statistically significant difference among the three tests in terms of VFI and PSD values (p=0.008 and p<0.001, respectively).</p><p><strong>Conclusion: </strong>Test duration was found to be shorter in the SFR test when compared to SS and SF tests. However, all three tests were similar in terms of the width and depth of the glaucomatous VF defect.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"55 2","pages":"67-73"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rational Drug Use in Extraocular Surgeries","authors":"Dudu Deniz Açar, Yasemin Aslan Katırcıoğlu","doi":"10.4274/tjo.galenos.2024.55313","DOIUrl":"10.4274/tjo.galenos.2024.55313","url":null,"abstract":"<p><p>Extraocular surgeries include a broad spectrum of procedures such as pterygium excision, removal of conjunctival tumors, and orbital exenteration. The objective of these surgeries is to address various ocular conditions, enhance visual function, and rectify cosmetic concerns. Nonetheless, as with any invasive procedure, these surgeries carry a risk of infection. To curtail this risk, prophylactic antibiotics are commonly used after extraocular surgeries. Administered via topical, oral, or intravenous routes, these antibiotics aim to prevent potential postoperative bacterial infections. The selection of these antibiotics is guided by their efficacy against prevalent pathogens associated with ocular infections, including <i>Staphylococcus epidermidis</i> and <i>Pseudomonas aeruginosa</i>. The choice of antibiotic, its route of administration, and duration of therapy can vary depending on the specifics of the surgery and individual patient risk factors. Moreover, in the context of extraocular surgeries, specific agents such as mitomycin C (MMC), interferon (IFN) alpha-2b, and 5-fluorouracil serve unique roles extending beyond infection prevention. MMC, an antitumor agent, aids in averting scarring and fibrosis in procedures like pterygium and glaucoma surgeries. IFN alpha-2b, with its antiviral and antiproliferative properties, is utilized to decrease the recurrence of conjunctival and corneal neoplasias postoperatively. This review examines the current understanding of prophylactic antibiotic use in certain extraocular surgeries and the role of antibiotics and some specific agents in enhancing surgical outcomes.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":" ","pages":"92-98"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"West Nile Virus Chorioretinitis: First Case with Ocular Involvement in Türkiye.","authors":"Özlem Özkan, Anıl Akdeniz, Ziya Ayhan, Arzu Nazlı, Ali Osman Saatci","doi":"10.4274/tjo.galenos.2025.05673","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2025.05673","url":null,"abstract":"<p><p>A 59-year-old man who experienced severe visual loss in the right eye for two days following a febrile illness (high fever lasting for 15 days) presented to our center for a second opinion. On examination, his Snellen best corrected visual acuity (BCVA) was 1/10 in the right eye and 9/10 in the left eye. On fundoscopy, we observed a few track-like, cream-colored linear lesions in the superior fundus of the left eye and a small whitish foveal discoloration together with a temporally pallid disc in the right eye. On autofluorescence imaging, there were some scattered hyperautofluorescent patchy areas bilaterally and, most notably, several hyperautofluorescent track-like lines in the left eye. A complete systemic evaluation was carried out and a blood sample was sent via the Provincial Health Directorate for West Nile virus (WNV) polymerase chain reaction and immunoglobulin (Ig) M and G testing. IgM and IgG antibodies were detected by immunofluorescence assay. The diagnosis was bilateral WNV chorioretinopathy. Magnetic resonance imaging of the brain ruled out any central nervous system involvement. A right intravitreal ranibizumab injection was administered for the intraretinal edema. A month later, Snellen BCVA was 2/10 in the right eye 10/10 in the left. Hyperautofluorescent lesions were no longer detectable in either eye but the right optic disc still appeared pallid. Clinicians should suspect WNV horioretinitis in cases presenting with characteristic fundus lesions and a history of febrile illness.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"55 2","pages":"99-104"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oculoplastic Challenges in Patients with Glaucoma.","authors":"Serdar Bayraktar, Kübra Serbest Ceylanoğlu, Emine Şen","doi":"10.4274/tjo.galenos.2024.67124","DOIUrl":"https://doi.org/10.4274/tjo.galenos.2024.67124","url":null,"abstract":"<p><p>Glaucoma is typically a disease that occurs in advanced age, requiring lifelong monitoring and treatment with topical medications, laser procedures, or surgery. Patients with glaucoma may also experience oculoplastic issues due to the natural aging process or as a result of glaucoma treatment or surgery. Eyelid surgery in these individuals can lead to complications and undesirable results. Therefore, it is crucial for oculoplastic surgeons to be aware of the incidence and risk factors associated with oculoplastic problems specific to glaucoma patients. Understanding these potential complications is essential for taking necessary precautions and achieving successful surgical outcomes. The purpose of this review is to raise awareness among ophthalmologists specializing in oculoplasty and glaucoma and to contribute to the quality of life of glaucoma patients.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics and Analysis of Spontaneous Consecutive Exotropia in Children with Refractive Accommodative Esotropia.","authors":"Aysel Pelit, Nazife Sefi Yurdakul","doi":"10.4274/tjo.galenos.2024.68745","DOIUrl":"10.4274/tjo.galenos.2024.68745","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the clinical characteristics and risk factors associated with spontaneous consecutive exotropia (ScXT) in children diagnosed with refractive accommodative esotropia (RAET).</p><p><strong>Materials and methods: </strong>A retrospective analysis of medical records was conducted on 19 patients who demonstrated a spontaneous transition from RAET to exotropia (XT). Patients who received strabismus surgery or botulinum toxin injection were excluded from the study. The control group consisted of 31 age-matched patients with RAET who demonstrated successful optical alignment at both near and distance. The ophthalmological examination findings of the study and control groups were compared. Independent two-sample t-test and Pearson's chi-square test were used to evaluate the data of the patients.</p><p><strong>Results: </strong>The study examined patients diagnosed with RAET who developed consecutive XT. Among them, 15 (78.9%) were female and 4 (21.1%) were male. The mean age at esotropia (ET) onset was 22.68 months (standard deviation [SD]: 12.91). The control group consisted of 16 (51.6%) female and 15 (48.4%) male patients, with a mean age at ET onset of 25.09 months (SD: 15.47). Mean age at onset did not differ between the groups (p=0.55). The mean interval between ET onset and appearance of XT was 7.53 years (SD: 1.49). Cycloplegic refraction measurements taken during the initial examination indicated that the study group exhibited greater degrees of hypermetropia in their right (p=0.01) and left (p=0.04) eyes than did the control group. Furthermore, the incidence of inferior oblique muscle overaction was higher among the study group (p=0.03).</p><p><strong>Conclusion: </strong>The findings indicate that patients with high hypermetropic refraction values should be monitored for an extended period due to the increased risk of developing subsequent XT. Concomitant inferior oblique overaction can increase the risk of ScXT.</p>","PeriodicalId":23373,"journal":{"name":"Turkish Journal of Ophthalmology","volume":"55 1","pages":"6-10"},"PeriodicalIF":0.0,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}