Tuberculosis and Respiratory Diseases最新文献_第3页

Authors´ Response: Additional Analyses of Nutritional Intake and Muscle Strength in Individuals with Airflow Limitation. 作者的回应：对气流受限个体的营养摄入和肌肉力量的额外分析。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-04-01 Epub Date: 2025-02-06 DOI: 10.4046/trd.2024.0184

I Re Heo, Ho Cheol Kim

引用次数: 0

Features of Lung Cyst in Birt-Hogg-Dubé Syndrome from Patients with Multiple Lung Cysts. 多发性肺囊肿患者的 Birt-Hogg-Dubé 综合征肺囊肿特征。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-04-01 Epub Date: 2024-11-25 DOI: 10.4046/trd.2024.0045

Yong Jun Choi, Hye Jung Park, Chi Young Kim, Bo Mi Jung, Jae Hwa Cho, Min Kwang Byun

{"title":"Features of Lung Cyst in Birt-Hogg-Dubé Syndrome from Patients with Multiple Lung Cysts.","authors":"Yong Jun Choi, Hye Jung Park, Chi Young Kim, Bo Mi Jung, Jae Hwa Cho, Min Kwang Byun","doi":"10.4046/trd.2024.0045","DOIUrl":"10.4046/trd.2024.0045","url":null,"abstract":"Background: High-resolution chest computed tomography (CT) is a crucial assessment tool for diagnosing Birt-Hogg-Dubé (BHD) syndrome. This study aimed to analyze differences of lung cysts between BHD and other cystic lung diseases.Methods: From January 2020 to December 2022, patients with multiple lung cysts who underwent chest CT at Gangnam Severance Hospital were included.Results: Over a 3-year period (from January 2020 to December 2022), out of 52,823 patients who underwent a chest CT scan, 301 (0.6%) patients with multiple lung cysts were enrolled in this study. Of enrolled patients, 24 (8.0%) were diagnosed with BHD. In patients with BHD, 95.8% exhibited bilateral cysts, and 83.3% showed basal predominance. The cysts' maximal diameter averaged 32.1 mm (interquartile range, 26.5 to 43.5). Additionally, 95.8% of patients with BHD had diverse cyst sizes and morphologies. Multivariate logistic regression analysis revealed that bilateral cysts (odds ratio [OR], 12.393; 95% confidence interval [CI], 1.613 to 274.682; p=0.038), basal predominance (OR, 8.511; 95% CI, 2.252 to 39.392; p=0.002), maximum diameter (OR, 1.053; 95% CI, 1.009 to 1.108; p=0.032), and diversity of morphology (OR, 19.513; 95% CI, 2.833 to 398.119; p=0.010) were significant factors associated with BHD diagnosis. A multivariate prediction model for BHD diagnosis demonstrated a sensitivity of 95.83%, a specificity of 81.22%, and an area under the receiver operating characteristic curve of 0.951 (95% CI, 0.914 to 0.987).Conclusion: Distinguishing features of lung cysts from other cystic lung diseases include bilateral cysts, basal dominance, large size, and irregular shape.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":"388-398"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding of Patients with Severe COVID-19 Using Lung Ultrasound. 肺部超声对重症COVID-19患者的了解。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-04-01 Epub Date: 2025-01-06 DOI: 10.4046/trd.2024.0025

Seo-Hee Yang, Eun Ju Park, Jung-Hyun Kim, Jin Woo Song, Young-Jae Cho

{"title":"Understanding of Patients with Severe COVID-19 Using Lung Ultrasound.","authors":"Seo-Hee Yang, Eun Ju Park, Jung-Hyun Kim, Jin Woo Song, Young-Jae Cho","doi":"10.4046/trd.2024.0025","DOIUrl":"10.4046/trd.2024.0025","url":null,"abstract":"Background: Lung ultrasound (LUS) has proven valuable in the initial assessment of coronavirus disease 2019 (COVID-19), but its role in detecting pulmonary fibrosis following intensive care remains unclear. This study aims to assess the presence of pulmonary sequelae and fibrosis-like changes using LUS in survivors of severe COVID-19 pneumonia one month after discharge.Methods: We prospectively enrolled patients with severe COVID-19 who required mechanical ventilation in the intensive care unit (ICU) and conducted LUS assessments from admission to the outpatient visit after discharge. We tracked changes in key LUS findings and applied our proprietary LUS scoring system. To evaluate LUS accuracy, we correlated measured LUS values with computed tomography scores.Results: We evaluated B-line presence, pleural thickness, and consolidation in 14 eligible patients. The LUS scores exhibited minimal changes, with values of 19.1, 19.2, and 17.5 at admission, discharge, and the outpatient visit, respectively. Notably, the number of B-lines decreased significantly, from 1.92 at admission to 0.56 at the outpatient visit (p<0.05), while pleural thickness increased significantly, from 2.05 at admission to 2.48 at the outpatient visit (p≤0.05).Conclusion: This study demonstrates that LUS can track changes in lung abnormalities in severe COVID-19 patients from ICU admission through to outpatient follow-up. While pleural thickening and B-line patterns showed significant changes, no correlation was found between LUS and high-resolution computed tomography fibrosis scores. These findings suggest that LUS may serve as a supplementary tool for assessing pulmonary recovery in severe COVID-19 cases.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":"380-387"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Home High-Flow Nasal Cannula in Patients with Chronic Respiratory Failure: A Literature Review and Suggestions for Clinical Practice. 家用高流量鼻插管治疗慢性呼吸衰竭：文献回顾及临床应用建议。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-04-01 Epub Date: 2025-02-18 DOI: 10.4046/trd.2024.0196

Youjin Chang, Moon Seong Baek, Sei Won Kim, Su Hwan Lee, Jung Soo Kim, So Young Park, Jin Woo Kim, Jae Hwa Cho, Sunghoon Park

{"title":"Home High-Flow Nasal Cannula in Patients with Chronic Respiratory Failure: A Literature Review and Suggestions for Clinical Practice.","authors":"Youjin Chang, Moon Seong Baek, Sei Won Kim, Su Hwan Lee, Jung Soo Kim, So Young Park, Jin Woo Kim, Jae Hwa Cho, Sunghoon Park","doi":"10.4046/trd.2024.0196","DOIUrl":"10.4046/trd.2024.0196","url":null,"abstract":"High-flow nasal cannula (HFNC) is a noninvasive respiratory support system that delivers air that is heated at 31°C-38°C, humidified 100%, and oxygen-enriched at a constant high flow rate of 15-60 L/min. Because of its numerous physiological benefits, convenience, and minimal side effects, HFNC has been increasingly used over the past decade in patients with acute hypoxemic respiratory failure, yet the clinical benefits of long-term HFNC remain uncertain. Several studies have suggested its potential use as an alternative home oxygen therapy for patients with chronic stable lung diseases, such as chronic obstructive pulmonary disease (COPD), interstitial lung disease, and bronchiectasis. The use of long-term home HFNC in patients with chronic respiratory failure is an emerging area with promising potential. Despite limited clinical research, this review aims to describe the physiology of HFNC use and summarize the current evidence on its long-term application, to provide healthcare providers with insights and perspectives on the potential role of long-term home HFNC.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":"264-277"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacologic Therapies for Preventing Chronic Obstructive Pulmonary Disease Exacerbations: A Comprehensive Review. 预防COPD恶化的药物治疗：一项综合综述。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-04-01 Epub Date: 2025-02-04 DOI: 10.4046/trd.2024.0170

Hyun Woo Lee

{"title":"Pharmacologic Therapies for Preventing Chronic Obstructive Pulmonary Disease Exacerbations: A Comprehensive Review.","authors":"Hyun Woo Lee","doi":"10.4046/trd.2024.0170","DOIUrl":"10.4046/trd.2024.0170","url":null,"abstract":"Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by acute exacerbations that accelerate disease progression, increase hospitalizations, and elevate mortality. Effective management focuses on preventing these exacerbations owing to their significant impact on long-term outcomes. This review compiles current evidence regarding pharmacologic interventions aimed at reducing exacerbations, which include inhaled therapies, oral treatments, and novel agents. Established inhaled agents, such as long-acting beta-agonists, long-acting muscarinic antagonists, and combinations of inhaled corticosteroids, are fundamental, with the personalized selection based on patient-specific factors like blood eosinophil levels and history of exacerbations. Oral treatments, including roflumilast and azithromycin, confer additional benefits for patients with particular characteristics, such as chronic bronchitis or frequent exacerbations. Roflumilast effectively reduces exacerbations as a phosphodiesterase 4 (PDE-4) inhibitor in conjunction with inhaled therapies, while azithromycin provides anti-inflammatory and antimicrobial properties, particularly advantageous for elderly former smokers. Innovative therapies such as ensifentrine, a dual PDE-3/4 inhibitor, and dupilumab, which targets type 2 inflammation, demonstrate potential for lowering exacerbations in specific subgroups. This body of evidence endorses a personalized, phenotype-driven approach to COPD management, aimed at optimizing therapeutic strategies to decrease exacerbation frequency and enhance patient outcomes.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":"216-227"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Korean Guidelines for Diagnosis and Management of Idiopathic Nonspecific Interstitial Pneumonia. 韩国特发性非特异性间质性肺炎诊断和治疗指南。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-04-01 Epub Date: 2025-01-06 DOI: 10.4046/trd.2024.0168

Yong Suk Jo, Hyun-Kyung Lee, Sun Hyo Park, Joon Sung Joh, Hye Jin Jang, Jong Sun Park

{"title":"Korean Guidelines for Diagnosis and Management of Idiopathic Nonspecific Interstitial Pneumonia.","authors":"Yong Suk Jo, Hyun-Kyung Lee, Sun Hyo Park, Joon Sung Joh, Hye Jin Jang, Jong Sun Park","doi":"10.4046/trd.2024.0168","DOIUrl":"https://doi.org/10.4046/trd.2024.0168","url":null,"abstract":"Idiopathic nonspecific interstitial pneumonia (iNSIP) is recognized as a distinct entity among various types of idiopathic interstitial pneumonias. It is identified histologically by the nonspecific interstitial pneumonia pattern. A diagnosis of iNSIP is feasible once secondary causes or underlying diseases are ruled out. Usually presenting with respiratory symptoms such as shortness of breath and cough, iNSIP has a subacute or chronic course. It predominantly affects females aged 50 to 60 years who are non-smokers. Key imaging findings on chest high-resolution computed tomography include bilateral reticular opacities in lower lungs, traction bronchiectasis, reduced lung volumes and, ground-glass opacities. Abnormalities are typically diffuse across both lungs with subpleural distributions. Treatment often involves systemic steroids, either alone or in combination with other immunosuppressants, although evidence supporting effectiveness of these treatments is limited. Prognosis is generally more favorable for iNSIP than for idiopathic pulmonary fibrosis, with many studies reporting a 5-year survival rate above 70%. Antifibrotic agents should be considered in a condition, termed progressive pulmonary fibrosis, where pulmonary fibrosis progressively worsens.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":"88 2","pages":"237-246"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Park 7. Sarcoidosis. 韩国肺间质性疾病的诊断和管理指南：Park 7。结节病。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-04-01 DOI: 10.4046/trd.2024.0202

Eun Joo Lee, Yangjin Jegal, Dong Won Park, Jimyung Park, Jun-Pyo Myong, Ji-Hyun Lee, Bo Hyoung Kang

{"title":"Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Park 7. Sarcoidosis.","authors":"Eun Joo Lee, Yangjin Jegal, Dong Won Park, Jimyung Park, Jun-Pyo Myong, Ji-Hyun Lee, Bo Hyoung Kang","doi":"10.4046/trd.2024.0202","DOIUrl":"https://doi.org/10.4046/trd.2024.0202","url":null,"abstract":"Sarcoidosis is a granulomatous inflammatory disease of unknown etiology that can affect the entire body, but respiratory tract involvement is most common. In radiological findings, bilateral hilar and mediastinal lymph node enlargement is the most common finding, and when lung parenchyma is involved, findings such as micronodules, ground-glass shadows, reticular shadows, and fibrosis are seen. Biopsies for histological diagnosis are mainly performed on lymph nodes or lungs, and mediastinal lymph node biopsies are done via endobronchochial ultrasound-guided fine needle aspiration. Pathological findings are characterized by non-caseating, non-necrotizing granulomas, and in Korea, differentiation from tuberculosis is especially important. The natural history of sarcoidosis is very variable, with approximately two-thirds of subjects showing spontaneous remission and only 10-30% of patients showing a chronic or progressive form. The most important factor in determining treatment is whether there is a risk of death, organ failure, or loss of quality of life. Glucocorticosteroids are the mainstay of treatment, and if the disease progresses despite treatment, or if glucocorticosteroids cannot be reduced or cannot be used, immunosuppressants such as methotrexate and azathioprine can be considered. Response to glucocorticosteroids treatment is good, and most of the patients stabilize or improve, with a low mortality rate around 3-5%.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of Artificial Intelligence in Thoracic Radiology: A Narrative Review. 人工智能在胸部放射学中的应用：人工智能在胸部放射学中的应用：叙述性综述（人工智能在胸部放射学中的应用）。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-04-01 Epub Date: 2024-12-17 DOI: 10.4046/trd.2024.0062

Woo Hyeon Lim, Hyungjin Kim

引用次数: 0

Kernel Conversion Improves the Correlation between the Extent of Emphysema and Clinical Parameters in Chronic Obstructive Pulmonary Disease: A Multicenter Cohort Study. 核转换改善COPD患者肺气肿程度与临床参数的相关性：一项多中心队列研究。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-04-01 Epub Date: 2025-02-04 DOI: 10.4046/trd.2024.0166

Tai Joon An, Youlim Kim, Hyun Lee, Hyeon-Kyoung Koo, Naoya Tanabe, Kum Ju Chae, Kwang Ha Yoo

{"title":"Kernel Conversion Improves the Correlation between the Extent of Emphysema and Clinical Parameters in Chronic Obstructive Pulmonary Disease: A Multicenter Cohort Study.","authors":"Tai Joon An, Youlim Kim, Hyun Lee, Hyeon-Kyoung Koo, Naoya Tanabe, Kum Ju Chae, Kwang Ha Yoo","doi":"10.4046/trd.2024.0166","DOIUrl":"10.4046/trd.2024.0166","url":null,"abstract":"Background: Computed tomography (CT) scans are utilized to assess emphysema, a prominent phenotype of chronic obstructive pulmonary disease (COPD). Variability in CT protocols and equipment across hospitals can impact accuracy. This study aims to implement kernel conversion across different CT settings and evaluate changes in the correlation between the emphysema index pre- and post-kernel conversion, along with clinical measures in COPD patients.Methods: Data were extracted from the Korea COPD Subgroup Study database, which included CT scan images from 484 COPD patients. These images underwent kernel conversion. Emphysema extent was quantified using the percentage of low-attenuation areas (%LAA-950) determined by a deep learning-based program. The correlation between %LAA-950 and clinical parameters, including lung function tests, the modified Medical Research Council (mMRC), 6-minute walking distance (6MWD), COPD assessment test (CAT), and the St. George's Respiratory Questionnaire for COPD (SGRQ-c), was analyzed. Subsequently, these values were compared across various CT settings.Results: A total of 484 participants were included. Kernel conversion significantly reduced the variance in %LAA-950 values (before vs. after: 12.6±11.0 vs. 8.8±11.9). Post-kernel conversion, %LAA-950 demonstrated moderate correlations with forced expiratory volume in 1 second (r=-0.41), residual volume/total lung capacity (r=0.42), mMRC (r=0.25), CAT score (r=0.12), SGRQ-c (r=0.21), and 6MWD (r=0.15), all of which were improved compared to the unconverted dataset (all p<0.01).Conclusion: CT images processed through kernel conversion enhance the correlation between the extent of emphysema and clinical parameters in COPD.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":"303-309"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Better Chemotherapeutic Response of Small Cell Lung Cancer in Never Smokers than in Smokers. 从不吸烟者比吸烟者对小细胞肺癌的化疗反应更好。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-04-01 Epub Date: 2025-02-11 DOI: 10.4046/trd.2024.0056

Ha-Young Park, Hyung-Joo Oh, Hwa Kyung Park, Joon-Young Yoon, Chang-Seok Yoon, Bo Gun Kho, Tae-Ok Kim, Hong-Joon Shin, Chul-Kyu Park, Yong-Soo Kwon, Yu-Il Kim, Sung-Chul Lim, Young-Chul Kim, In-Jae Oh

{"title":"Better Chemotherapeutic Response of Small Cell Lung Cancer in Never Smokers than in Smokers.","authors":"Ha-Young Park, Hyung-Joo Oh, Hwa Kyung Park, Joon-Young Yoon, Chang-Seok Yoon, Bo Gun Kho, Tae-Ok Kim, Hong-Joon Shin, Chul-Kyu Park, Yong-Soo Kwon, Yu-Il Kim, Sung-Chul Lim, Young-Chul Kim, In-Jae Oh","doi":"10.4046/trd.2024.0056","DOIUrl":"10.4046/trd.2024.0056","url":null,"abstract":"Background: Small cell lung cancer (SCLC) is called 'smoker's disease' because it is strongly associated with smoking and most cases occur in smokers. However, it can also occur in never smokers. We investigated the clinical features of never smokers with SCLC and compared their treatment outcomes with those of smokers with SCLC.Methods: We retrospectively reviewed the clinical data of patients who had proven SCLC and had received chemotherapy at a single cancer center between July 2002 and April 2021.Results: Of 1,643 patients, 1,416 (86.2%) were enrolled in this study. A total of 162 (11.4%) and 1,254 (88.6%) patients were never smokers and smokers, respectively. There were more female never smokers than smokers (n=130; 80.2% vs. 79, 6.3%, p=0.000), and the incidence of ischemic heart disease was lower among never smokers than among smokers (4/1,416, [2.5%] vs. 83/1,416 [6.6%], p=0.036). Never smokers showed less symptoms at diagnosis than smokers (80.9% vs. 87.2%, p=0.037); however, they showed more toxicity after first-line treatment (61.7% vs. 47.8%, p=0.001). The objective response rate (ORR) was significantly higher in never smokers (74.1% vs. 59.6%, p=0.000). In the multivariate analysis, never smoking and second-line treatment were associated with a better ORR. However, progression-free survival and overall survival were not significantly different between never smokers and smokers.Conclusion: In conclusion, never smokers accounted for 11.4% of patients with SCLC. They had distinguishing clinical characteristics and showed better chemotherapeutic responses than smokers.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":"334-341"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0