Tuberculosis and Respiratory Diseases最新文献_第4页

Korean Guidelines for the Management and Antibiotic Therapy in Adult Patients with Hospital-Acquired Pneumonia. 韩国医院获得性肺炎成人患者管理和抗生素治疗指南》。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-01-01 Epub Date: 2024-10-11 DOI: 10.4046/trd.2024.0135

Hayoung Choi, Kyung Hoon Min, Young Seok Lee, Youjin Chang, Bo Young Lee, Jee Youn Oh, Ae-Rin Baek, Jongmin Lee, Kyeongman Jeon

{"title":"Korean Guidelines for the Management and Antibiotic Therapy in Adult Patients with Hospital-Acquired Pneumonia.","authors":"Hayoung Choi, Kyung Hoon Min, Young Seok Lee, Youjin Chang, Bo Young Lee, Jee Youn Oh, Ae-Rin Baek, Jongmin Lee, Kyeongman Jeon","doi":"10.4046/trd.2024.0135","DOIUrl":"10.4046/trd.2024.0135","url":null,"abstract":"Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) are correlated with high morbidity and mortality rates. Guidelines that consider local epidemiologic data are fundamental for identifying optimal treatment strategies. However, Korea has no HAP/VAP guidelines. This study was conducted by a committee of nine experts from the Korean Academy of Tuberculosis and Respiratory Diseases Respiratory Infection Study Group using the results of Korean HAP/VAP epidemiologic studies. Eleven key questions for HAP/VAP diagnosis and treatment were addressed. The Convergence of Opinion on Suggestions and Evidence (CORE) process was used to derive suggestions, and evidence levels and recommendation grades were in accordance with the Grading of Recommendations Assessment Development and Evaluation (GRADE) methodology. Suggestions were made for the 11 key questions pertinent to diagnosis, biomarkers, antibiotics, and treatment strategies for adult patients with HAP/VAP. Using the CORE process and GRADE methodology, the committee generated a series of recommendations for HAP/VAP diagnosis and treatment in the Korean context.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":"69-89"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Miliary Tuberculosis Associated with Klebsiella pneumonia: Managing the Double Whammy of Antimicrobial Resistance. 伴有克雷伯氏菌肺炎的睫状体结核病：抗菌药耐药性的双重打击。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-01-01 Epub Date: 2024-10-30 DOI: 10.4046/trd.2024.0105

Priyavardhan Mishra, Mohit Kondisetti, Anant Patil, Nikhil Sarangdhar, Vijaykumar Gupta

引用次数: 0

Idiopathic Inflammatory Myopathies-Associated Interstitial Lung Disease in Adults. 成人特发性炎症性肌病相关间质性肺病

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-01-01 Epub Date: 2024-09-02 DOI: 10.4046/trd.2024.0072

Mitsuhiro Moda, Toyoshi Yanagihara, Ran Nakashima, Hiromitsu Sumikawa, Shigeki Shimizu, Toru Arai, Yoshikazu Inoue

{"title":"Idiopathic Inflammatory Myopathies-Associated Interstitial Lung Disease in Adults.","authors":"Mitsuhiro Moda, Toyoshi Yanagihara, Ran Nakashima, Hiromitsu Sumikawa, Shigeki Shimizu, Toru Arai, Yoshikazu Inoue","doi":"10.4046/trd.2024.0072","DOIUrl":"10.4046/trd.2024.0072","url":null,"abstract":"Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of autoimmune diseases characterized by muscle involvement and various extramuscular manifestations. Interstitial lung disease (ILD) is one of the most common extramuscular manifestations of IIM and is associated with significant mortality and morbidity. The clinical phenotypes, treatment responses, and prognosis of IIM-ILD are significantly related to myositis-specific antibody (MSA) profiles, with some racial differences. The features associated with MSA in IIM-ILD could also be relevant to cases of ILD where MSA is present but does not meet the criteria for IIM. The anti-melanoma differentiation-associated gene 5 antibody is highly associated with rapidly progressive ILD (RP-ILD), especially in Asian populations, and with characteristic cutaneous manifestations, such as skin ulcers. Radiologically, ground-glass opacities, consolidations, and nonsegmental linear opacities were more predominant than reticular opacities and honeycombing. While the mortality rate is still around 30%, the prognosis can be improved with early intensive therapy with corticosteroids and multiple immunosuppressants. In contrast, anti-aminoacyl-tRNA synthetase (ARS) antibodies are associated with chronic ILD, although RP-ILD is also common. Patients with anti-ARS antibodies often show lung-predominant presentations, with subtle muscle and skin involvement. Radiologically, reticular opacities, with or without consolidation, are predominant and may progress to honeycombing over time. Combination therapy with corticosteroids and a single immunosuppressant is recommended to prevent relapses, which often lead to a decline in lung function and fatal long-term outcomes. Significant advances in immunology and genetics holds promise for fostering more personalized approaches to managing IIMILD.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":"26-44"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond the Spirometry: New Diagnostic Modalities in Chronic Obstructive Pulmonary Disease. 肺活量测定之外：慢性阻塞性肺病的新诊断模式。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-01-01 Epub Date: 2024-09-23 DOI: 10.4046/trd.2024.0040

Jin Hwa Song, Youlim Kim

引用次数: 0

Clinical Profiles of Multidrug-Resistant and Rifampicin-Monoresistant Tuberculosis in Korea, 2018-2021: A Nationwide Cross-Sectional Study. 2018-2021年韩国耐多药结核病和耐利福平单耐药结核病的临床概况：一项全国性横断面研究。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-01-01 Epub Date: 2024-09-23 DOI: 10.4046/trd.2024.0049

Jinsoo Min, Yousang Ko, Hyung Woo Kim, Hyeon-Kyoung Koo, Jee Youn Oh, Doosoo Jeon, Taehoon Lee, Young-Chul Kim, Sung Chul Lim, Sung Soon Lee, Jae Seuk Park, Ju Sang Kim

{"title":"Clinical Profiles of Multidrug-Resistant and Rifampicin-Monoresistant Tuberculosis in Korea, 2018-2021: A Nationwide Cross-Sectional Study.","authors":"Jinsoo Min, Yousang Ko, Hyung Woo Kim, Hyeon-Kyoung Koo, Jee Youn Oh, Doosoo Jeon, Taehoon Lee, Young-Chul Kim, Sung Chul Lim, Sung Soon Lee, Jae Seuk Park, Ju Sang Kim","doi":"10.4046/trd.2024.0049","DOIUrl":"10.4046/trd.2024.0049","url":null,"abstract":"Background: This study aimed to identify the clinical characteristics of multidrug-resistant/ rifampicin-resistant tuberculosis (MDR/RR-TB) in the Republic of Korea.Methods: Data of notified people with tuberculosis between July 2018 and December 2021 were retrieved from the Korea Tuberculosis Cohort database. MDR/RR-TB was further categorized according to isoniazid susceptibility as follows: multidrug-resistant tuberculosis (MDR-TB), rifampicin-monoresistant tuberculosis (RMR-TB), and RR-TB if susceptibility to isoniazid was unknown. Multivariable logistic regression analysis was conducted to identify the factors associated with MDR/RR-TB.Results: Between 2018 and 2021, the proportion of MDR/RR-TB cases among all TB cases and TB cases with known drug susceptibility test results was 2.1% (502/24,447). The proportions of MDR/RR-TB and MDR-TB cases among TB cases with known drug susceptibility test results were 3.3% (502/15,071) and 1.9% (292/15,071), respectively. Among all cases of rifampicin resistance, 31.7% (159/502) were RMR-TB and 10.2% (51/502) were RR-TB. Multivariable logistic regression analyses revealed that younger age, foreigners, and prior tuberculosis history were significantly associated with MDR/ RR-TB.Conclusion: Rapid identification of rifampicin resistance targeting the high-risk populations, such as younger generations, foreign-born individuals, and previously treated patients are necessary for patient-centered care.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":"159-169"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive Strategies for Preoperative Pulmonary Risk Evaluation and Management. 术前肺部风险评估和管理的综合策略。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-01-01 Epub Date: 2024-10-30 DOI: 10.4046/trd.2024.0118

Hyo Jin Lee, Hyun Woo Lee

{"title":"Comprehensive Strategies for Preoperative Pulmonary Risk Evaluation and Management.","authors":"Hyo Jin Lee, Hyun Woo Lee","doi":"10.4046/trd.2024.0118","DOIUrl":"10.4046/trd.2024.0118","url":null,"abstract":"Postoperative pulmonary complications (PPCs) significantly increase morbidity and mortality in surgical patients, particularly those with pulmonary conditions. PPC incidence varies widely, influenced by factors such as surgery type, patient age, smoking status, and comorbid conditions, including chronic obstructive pulmonary disease (COPD) and congestive heart failure. While preoperative pulmonary function tests and chest radiographs are crucial for lung resection surgery, their use should be judiciously tailored to individual risk profiles. Effective risk stratification models, such as the American Society of Anesthesiologists classification, Arozullah respiratory failure index, Gupta Calculators, and Assess Respiratory Risk in Surgical Patients in Catalonia (ARISCAT) model, play a key role in predicting PPCs. Key strategies to diminish PPCs include preoperative optimization of respiratory conditions, smoking cessation, and respiratory rehabilitation. In patients with COPD and asthma, it is crucial to maintain optimal disease control through inhaled therapies, systemic corticosteroids, and tailored preoperative respiratory exercises. Anemia and hypoalbuminemia are significant predictors of PPCs and require meticulous management. The choice and duration of anesthesia also notably influence PPC risk, with regional anesthesia being preferable to general anesthesia when possible. Comprehensive preoperative evaluations and tailored interventions are essential for enhancing surgical outcomes and reducing PPC incidence. Additional studies involving domestic patients are necessary to refine national guidelines for managing those at risk of PPCs.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":"90-108"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Air Pollution and Interstitial Lung Disease. 空气污染与间质性肺病。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-01-01 Epub Date: 2024-11-14 DOI: 10.4046/trd.2024.0116

Yong Suk Jo, Jin Woo Song

{"title":"Air Pollution and Interstitial Lung Disease.","authors":"Yong Suk Jo, Jin Woo Song","doi":"10.4046/trd.2024.0116","DOIUrl":"10.4046/trd.2024.0116","url":null,"abstract":"This review article explores the multifaceted relationship between air pollution and interstitial lung diseases (ILDs), particularly focusing on idiopathic pulmonary fibrosis, the most severe form of fibrotic ILD. Air pollutants are mainly composed of particulate matter, ozone (O3), nitrogen dioxide (NO2), carbon monoxide (CO), and sulfur dioxide (SO2). They are recognized as risk factors for several respiratory diseases. However, their specific effects on ILDs and related mechanisms have not been thoroughly studied yet. Emerging evidence suggests that air pollutants may contribute to the development and acute exacerbation of ILDs. Longitudinal studies have indicated that air pollution can adversely affect the prognosis of disease by decreasing lung function and increasing mortality. Lots of in vitro, in vivo , and epidemiologic studies have proposed possible mechanisms linking ILDs to air pollution, including inflammation and oxidative stress induced by exposure to air pollutants, which may induce mitochondrial dysfunction, promote cellular senescence, and disrupt normal epithelial repair processes. Despite these findings, effective interventions to mitigate effects of air pollution on ILD are not well established yet. This review emphasizes the urgent need to address air pollution as a key environmental risk factor for ILDs and calls for further studies to clarify its effects and develop preventive and therapeutic strategies.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":"45-55"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis and Treatment of Latent Tuberculosis Infection in Adults in South Korea. 韩国成人潜伏肺结核感染的诊断和治疗

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-01-01 Epub Date: 2024-10-04 DOI: 10.4046/trd.2024.0122

Kyung-Wook Jo, Young Soon Yoon, Hyung Woo Kim, Joong-Yub Kim, Young Ae Kang

引用次数: 0

Association of Nutritional Intake with Physical Activity and Handgrip Strength in Individuals with Airflow Limitation. 气流受限患者的营养摄入与体力活动和握力的关系

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-01-01 Epub Date: 2024-10-11 DOI: 10.4046/trd.2024.0017

I Re Heo, Tae Hoon Kim, Jong Hwan Jeong, Manbong Heo, Sun Mi Ju, Jung-Wan Yoo, Seung Jun Lee, Yu Ji Cho, Yi Yeong Jeong, Jong Deog Lee, Ho Cheol Kim

{"title":"Association of Nutritional Intake with Physical Activity and Handgrip Strength in Individuals with Airflow Limitation.","authors":"I Re Heo, Tae Hoon Kim, Jong Hwan Jeong, Manbong Heo, Sun Mi Ju, Jung-Wan Yoo, Seung Jun Lee, Yu Ji Cho, Yi Yeong Jeong, Jong Deog Lee, Ho Cheol Kim","doi":"10.4046/trd.2024.0017","DOIUrl":"10.4046/trd.2024.0017","url":null,"abstract":"Background: We investigated whether nutritional intake is associated with physical activity (PA) and handgrip strength (HGS) in individuals with airflow limitation.Methods: This study analyzed data from the 2014 and 2016 Korean National Health and Nutrition Examination Survey. We assessed total protein intake (g/day), caloric intake (kcal/day), and other nutritional intakes, using a 24-hour dietary recall questionnaire. HGS was measured three times for each hand using a digital grip strength dynamometer, and PA was assessed as health-enhancing PA. Airflow limitation was defined as a forced expiratory volume/forced vital capacity ratio of 0.7 in individuals over 40 years of age. Participants were categorized into groups based on their PA levels and HGS measurements: active aerobic PA vs. non-active aerobic PA, and normal HGS vs. low HGS.Results: Among the 622 individuals with airflow limitation, those involved in active aerobic PA and those with higher HGS had notably higher total food, calorie, water, protein, and lipid intake. The correlations between protein and caloric intake with HGS were strong (correlation coefficients=0.344 and 0.346, respectively). The forest plots show that higher intakes of food, water, calories, protein, and lipids are positively associated with active aerobic PA, while higher intakes of these nutrients are inversely associated with low HGS. However, in the multivariate logistic regression analysis, no significant associations were observed between nutritional intake and active aerobic PA or HGS.Conclusion: Nutritional intake was found to not be an independent factor associated with PA and HGS. However, the observed correlations suggest potential indirect effects that warrant further investigation.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":"120-129"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dry Medical Thoracoscopy with Artificial Pneumothorax Induction Using Veress Needle. 使用维雷斯针进行人工气胸诱导的干式医疗胸腔镜检查。

IF 2.5

Tuberculosis and Respiratory Diseases Pub Date : 2025-01-01 Epub Date: 2024-11-14 DOI: 10.4046/trd.2024.0029

Nai-Chien Huan, Sze Shyang Kho, Larry Ellee Nyanti, Hema Yamini Ramarmuty, Muhammad Aklil Abd Rahim, Rong Lih Ho, Shan Min Lo, Siew Teck Tie, Kunji Kannan Sivaraman Kannan

{"title":"Dry Medical Thoracoscopy with Artificial Pneumothorax Induction Using Veress Needle.","authors":"Nai-Chien Huan, Sze Shyang Kho, Larry Ellee Nyanti, Hema Yamini Ramarmuty, Muhammad Aklil Abd Rahim, Rong Lih Ho, Shan Min Lo, Siew Teck Tie, Kunji Kannan Sivaraman Kannan","doi":"10.4046/trd.2024.0029","DOIUrl":"10.4046/trd.2024.0029","url":null,"abstract":"Background: In the absence of significant pleural effusion, conventional medical thoracoscopy (MT) is often not feasible due to the risk of lung injury. Dry MT mitigates these risks by inducing artificial pneumothorax through needle insufflation or blunt dissection. Although the Veress needle is commonly used by surgeons to create pneumoperitoneum before laparoscopic surgeries, its application in dry MT has not been widely reported in recent times.Methods: We report on a series of 31 patients who underwent dry MT with artificial pneumothorax induction using Veress needle under thoracic ultrasonography (TUS) guidance. A procedure was considered technically successful if it met all the following criteria: successful pneumothorax induction, allowing smooth insertion of the semi-rigid thoracoscope; absence of immediate significant procedural-related complications; and no delayed complications such as persistent air leaks, defined as leakage lasting more than 5 days necessitating extended chest tube placement.Results: Complete pneumothorax induction was achieved in 25 cases, resulting in an 80.6% technical success rate; however, biopsies were successfully performed in all cases. The most frequent histopathological diagnoses were malignancy (n=9, 29.0%), followed by inflammatory pleuritis (n=8, 25.8%) and tuberculosis (n=8, 25.8%). No procedural complications were reported.Conclusion: These results indicate that TUS-guided dry MT utilizing a Veress needle is technically feasible and secure when performed by experienced MT practitioners in TUS.","PeriodicalId":23368,"journal":{"name":"Tuberculosis and Respiratory Diseases","volume":" ","pages":"181-189"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0