Turkish Journal of Medical Sciences最新文献

{"title":"Production and characterization of Zn- and Cu-doped Y2O3-Al2O3-SiO2 (YAS) glass microspheres.","authors":"Fatma Ünal, Batur Ercan","doi":"10.55730/1300-0144.5888","DOIUrl":"https://doi.org/10.55730/1300-0144.5888","url":null,"abstract":"<p><strong>Background/aim: </strong>Y₂O₃-Al₂O₃-SiO₂ (YAS) glass microspheres are currently used in radioembolization treatment. However, abscess formation can occur following this treatment. This study aims to endow YAS glass microspheres with antibacterial properties to address the abscesses forming in patients after radioembolization treatment.</p><p><strong>Materials and methods: </strong>In this study, undoped YAS glass microspheres and those doped with antibacterial agents zinc (Zn) and/or copper (Cu) were successfully fabricated using a sol-gel derived method.</p><p><strong>Results: </strong>After heat treatment, the microspheres exhibited an amorphous structure. Additionally, the incorporation of Zn and/or Cu dopants did not alter the patterns observed in the X-ray diffraction analysis. Fourier transform infrared spectroscopy analysis detected Si-O-Si, Al-O-Al, and Y-O band vibrations within the structure. The presence of Zn and Cu dopants was confirmed through X-ray photoelectron spectroscopy analysis. Scanning electron microscopy revealed that all samples possessed a regular microsphere morphology, with average particle sizes ranging from 6 to 50 μm. These average particle sizes were further confirmed using a mastersizer.</p><p><strong>Conclusion: </strong>The antibacterial agent-doped YAS glass microspheres show promise in combating infections that occur following radioembolization treatment.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"54 5","pages":"1092-1101"},"PeriodicalIF":1.2,"publicationDate":"2024-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11518404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trend shift in proximal humeral fracture treatment: a detailed review of national shoulder arthroplasty data.","authors":"İbrahim Bozkurt, İbrahim Kaya, Umut Öktem, Sinan Yilmaz, Naim Ata, Mustafa Mahir Ülgü, Şuayip Birinci, Fatih Karaaslan, İzzet Bingöl, Durmuş Ali Öçgüder","doi":"10.55730/1300-0144.5884","DOIUrl":"https://doi.org/10.55730/1300-0144.5884","url":null,"abstract":"<p><strong>Background/aim: </strong>This study aimed to scrutinize nationwide utilization trends of shoulder arthroplasty for proximal humerus fractures (PHFs) using a comprehensive national surgical database.</p><p><strong>Materials and methods: </strong>A retrospective study was conducted with 4181 patients who underwent shoulder arthroplasty due to PHF between 2016 and 2022 using national health records. They are grouped as hemiarthroplasty (HA), anatomical total shoulder arthroplasty (TSA), and reverse shoulder arthroplasty (RSA). The patients' demographic data, length of hospital stay, revision histories, transfusion rates, mortality data, trends in arthroplasty methods over the years, the distribution of cases by hospital characteristics and geographical regions were analyzed.</p><p><strong>Results: </strong>Treatment with HA was administered to 22.1% of patients, TSA to 30.2%, and RSA to 47.7%. The lowest revision rate was observed after HA (4.3%), while higher rates were recorded after TSA (7.9%) and RSA (7.4%) (p = 0.019). It was observed that there was a significant increasing trend in RSA rates and a decreasing trend in HA and TSA rates over time (p < 0.001).</p><p><strong>Conclusion: </strong>From 2016 to 2022, there appears to have been a significant increase in the utilization of RSA for the arthroplasty treatment of proximal humeral fractures in Türkiye, and it is used more frequently than HA. However, revision rates after RSA are still higher than those after HA.</p><p><strong>Level of evidence: </strong>Level III, retrospective cohort study.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"54 5","pages":"1052-1059"},"PeriodicalIF":1.2,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11518356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of rigid and elastic registration methods in software-based targeted prostate biopsy: a multicenter cohort study.","authors":"Serhat Çetin, Serdar Çelik, Murat Yavuz Koparal, Güven Aslan, Sertaç Yazici, Bahadır Şahin, Sinan Sözen, Levent Türkeri","doi":"10.55730/1300-0144.5916","DOIUrl":"10.55730/1300-0144.5916","url":null,"abstract":"<p><strong>Background/aim: </strong>This study aims to compare the success rates of rigid registration (RR) and elastic registration (ER) systems in diagnosing all cancers and clinically significant prostate cancer (csPC) in software-based targeted prostate biopsies (TPBs) by performing matching analysis.</p><p><strong>Materials and methods: </strong>The data of 2061 patients from six centers where software-based TPB is performed were used. All cancer and csPC detection rates of the RR and ER systems were compared following Mahalanobis distance matching with the propensity score caliper method. Logistic regression analysis was applied to identify factors predicting clinically insignificant prostate cancer (ciPC) and csPC diagnoses. Additionally, the International Society of Urological Pathology Grade Group (ISUP GG) upgrade rates of RR and ER systems were compared between biopsy and radical prostatectomy pathologies.</p><p><strong>Results: </strong>The matched sample included 157 RR and 157 ER patients. No statistically significant difference was found between ER and RR in terms of csPC detection rate (28.0% vs. 22.3% respectively, p = 0.242). The detection rate of all cancers by ER compared to RR was found to be significantly higher (54.8% vs. 35.7% respectively p < 0.001,). No statistically significant difference was found between the ER and RR groups regarding pathological upgrade (39.7% vs. 24.2% respectively, p = 0.130). In the logistic regression analysis performed to determine the factors predicting ciPC, decreased prostate volume and ER system use were found to be independent predictive factors.</p><p><strong>Conclusion: </strong>While the detection rate of csPC was similar for the RR and ER systems, the detection rate of all cancers and ciPC was significantly higher with the ER systems.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"54 6","pages":"1327-1334"},"PeriodicalIF":1.2,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11673674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the biomarker potential and molecular targets of TIGD1 in lung cancer using bioinformatics.","authors":"Merve Gülsen Bal Albayrak, Tuğcan Korak, Murat Kasap, Gürler Akpinar","doi":"10.55730/1300-0144.5920","DOIUrl":"10.55730/1300-0144.5920","url":null,"abstract":"<p><strong>Background/aim: </strong>Lung cancer, a predominant contributor to cancer mortality, is characterized by diverse etiological factors, including tobacco smoking and genetic susceptibilities. Despite advancements, particularly in nonsmall-cell lung cancer (NSCLC), therapeutic options for lung squamous cell carcinoma (LUSC) are limited. Transposable elements (TEs) and their regulatory proteins, such as tigger transposable element derived (TIGD) family proteins, have been implicated in cancer development. TIGD1, upregulated in various cancers, including LUSC, lacks a defined function. The aim of our study was to elucidate the biological functions, associated pathways, and interacting proteins of TIGD1.</p><p><strong>Materials and methods: </strong>The GSE229260 microarray dataset was investigated using the GEO2R tool to identify the differentially expressed genes (DEGs) in TIGD1 silenced in A549 lung cancer cells in contrast to controls. Enrichment analyses and protein-protein interaction (PPI) network construction were performed to uncover key pathways using KEGG and STRING analyses. Hub genes were determined through the intersection of DEGs with lung cancer-related genes via Cytoscape software and the cytoHubba plug-in, and their functions were analyzed. Immune and stromal scores of hub genes were also evaluated using the ESTIMATE algorithm.</p><p><strong>Results: </strong>Analyzing microarray data from TIGD1-silenced A549 NSCLC cells, a total of 13 upregulated DEGs and 1 downregulated DEGs were identified. The TIGD1-associated DEGs revealed significant involvement in crucial molecular pathways, including the PI3K/AKT, FOXO, and p53 signaling pathways. The hub genes AKT1, BRAF, SRC, GAPDH, CCND1, CDKN2A, CTNNB1, KRAS, MYC, and TP53 emerged as central regulators of cell proliferation, apoptosis, and protein metabolism. The hub genes exhibited negative correlations with immune and stromal components in the tumor microenvironment, suggesting their potential as biomarkers for lung cancer therapy.</p><p><strong>Conclusion: </strong>This study elucidates the potential functions of TIGD1 in lung cancer and identifies promising biomarker candidates associated with TIGD1 gene expression, presenting potential therapeutic targets for lung cancer therapies.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"54 6","pages":"1369-1380"},"PeriodicalIF":1.2,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11673667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of written asthma action plan among asthma patients in Türkiye: a multicenter, cross-sectional, descriptive study.","authors":"Kurtuluş Aksu, Gürgün Tuğçe Vural Solak, Pınar Mutlu, Levent Cem Mutlu, Görkem Vayişoğlu Şahin, Burcu Yormaz, Aylin Çapraz, Ezgi Erdem Türe, Yavuzalp Solak, Funda Aksu","doi":"10.55730/1300-0144.5910","DOIUrl":"10.55730/1300-0144.5910","url":null,"abstract":"<p><strong>Background/aim: </strong>There is currently no data from Türkiye on whether, following a diagnosis of asthma, patients are given an asthma action plan to implement. There is also no data on whether patients can manage their treatment based on the provided asthma action plans. The present study aimed to determine the use of asthma action plans in Türkiye and the awareness levels of patients about these plans.</p><p><strong>Materials and methods: </strong>A multicenter, cross-sectional descriptive study was conducted in the outpatient immunology, allergy, and pulmonology clinics of secondary and tertiary healthcare centers. Adult asthmatics filled out a case registration form regarding age, sex, educational status, duration of asthma, and smoking history. Subjects answered the Global Initiative for Asthma (GINA) assessment of control questions, indicated whether they had previously been offered an asthma action plan, and if they had received one, whether they benefited from it.</p><p><strong>Results: </strong>Data from 265 asthmatic adults (mean age: 48.4 years, standard deviation: 13.4 years), including 194 (73.2%) females were analyzed. The asthma of 212 (80.0%) patients was controlled, and was uncontrolled in 53 (20.0%) patients. An asthma action plan had been mentioned to 91 (34.3%) of the 265 patients. Among these 91 patients, 85 (93.4%) had been given a written asthma action plan, and 85 (93.4%) stated that they had benefited from the plan. The rate of being given an asthma action plan was significantly lower for illiterate patients than for patients with any education (p < 0.001).</p><p><strong>Conclusion: </strong>The rate of mentioning an asthma action plan to asthmatic patients is low. However, almost all patients who received an asthma action plan benefitted significantly from the plan. Thus, it is important to give asthmatic patients an action plan, ideally in written form.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"54 6","pages":"1281-1285"},"PeriodicalIF":1.2,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11673651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BRAF inhibitor candidate molecule usnic acid might use both intrinsic and extrinsic pathways of apoptosis.","authors":"Burcu Pelin Büyük, Demet Cansaran Duman, Türker Duman","doi":"10.55730/1300-0144.5890","DOIUrl":"https://doi.org/10.55730/1300-0144.5890","url":null,"abstract":"<p><strong>Background/aim: </strong>Melanoma is one of the most aggressive cancers and treatment methods commonly used for patients with skin cancer include checkpoint and BRAF/MEK inhibitors, traditional chemotherapy drugs, radiation, and adjuvant treatment methods. Due to the resistance and toxic effects that patients develop against the drugs, an effective treatment method has not been developed for melanoma yet. In this study we evaluated the anticancer effect of usnic acid (UA) on A-375 melanoma cells and human epidermal melanocytes using the xCELLigence real-time cell analysis system.</p><p><strong>Materials and methods: </strong>To determine the cell death pathway through which UA exerts its antiproliferative effect, its potential for apoptotic effects was investigated. Caspase-3 and caspase-9 enzyme assays and the expression analysis of 84 genes from the apoptosis pathway were carried out in UA-treated and nontreated A-375 cells.</p><p><strong>Results: </strong>UA was found to have an antiproliferative effect on A-375 cells while it did not have a cytotoxic effect on human epidermal melanocytes. UA treatment led to statistically significant increases in both caspase-3 and caspase-9 enzyme activities. Moreover, the expression levels of 61 genes (mainly proapoptotic genes) were increased and the expression levels of 23 genes (mainly antiapoptotic genes) were decreased in response to UA treatment. This effect might have developed through both the extrinsic and intrinsic apoptosis pathways; however, the extrinsic pathway was more pronounced.</p><p><strong>Conclusion: </strong>As a result of the obtained findings, it could be concluded that UA might be a promising candidate drug molecule for melanoma treatment in the future through topical application or encapsulation with nanocarriers.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"54 5","pages":"1116-1126"},"PeriodicalIF":1.2,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11518357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Duple-MONDNet: duple deep learning-based mobile net for motor neuron disease identification.","authors":"Sony Helen, Joseph Jawhar","doi":"10.55730/1300-0144.5952","DOIUrl":"10.55730/1300-0144.5952","url":null,"abstract":"<p><strong>Background/aim: </strong>Motor neuron disease (MND) is a devastating neuron ailment that affects the motor neurons that regulate muscular voluntary actions. It is a rare disorder that gradually destroys aspects of neurological function. In general, MND arises as a result of a combination of natural, behavioral, and genetic influences. However, early detection of MND is a challenging task and manual identification is time-consuming. To overcome this, a novel deep learning-based duple feature extraction framework is proposed for the early detection of MND.</p><p><strong>Materials and methods: </strong>Diffusion tensor imaging tractography (DTI) images were initially analyzed for color and textural features using dual feature extraction. Local binary pattern (LBP)-based methods were used to extract textural data from images by examining nearby pixel values. A color information feature was then added to the LBP-based feature during the classification phase for extracting color features. A flattened image was then fed into the MONDNet for classifying normal and abnormal cases of MND based on color and texture features.</p><p><strong>Results: </strong>The proposed deep MONDNet is suitable because it achieved a detection rate of 99.66% and can identify MND in its early stages.</p><p><strong>Conclusion: </strong>The proposed mobile net model achieved an overall F1 score of 13.26%, 6.15%, 5.56%, and 5.96% compared to the BPNN, CNN, SVM-RFE, and MLP algorithms, respectively.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"55 1","pages":"140-151"},"PeriodicalIF":1.2,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between microbiota awareness, nutrition literacy, and health literacy among adolescents.","authors":"İzzet Ülker, Muhammet Ali Aydin, Metin Yildiz, Gönül Gökçay, Ayşe Elkoca, Mehmet Salih Yildirim, Abraham Tanimowo, Dursun Alper Yilmaz","doi":"10.55730/1300-0144.5871","DOIUrl":"https://doi.org/10.55730/1300-0144.5871","url":null,"abstract":"<p><strong>Background/aim: </strong>Microbiota awareness, nutritional literacy, and health literacy levels in adolescents have a significant impact on their health and well-being. This research was conducted to examine the relationship between microbiota awareness, nutrition literacy, and health literacy in adolescents.</p><p><strong>Material and methods: </strong>This research was structured with a descriptive-correlational design. The study population comprised adolescents aged 10-19 years, living in Türkiye (n = 739), between June 2022 and February 2024. Data were analyzed using SPSS 22.0, G*Power 3.1, and R programming language 4.1.3.</p><p><strong>Results: </strong>The total effect of the health literacy variable on nutritional literacy was 0.2311, and this was statistically significant at a 95% confidence interval (CI) (p < 0.05). In terms of the health literacy variable, the direct effect of the nutrition literacy variable on the microbiota awareness variable was 0.2888, and this was statistically significant at the 95% CI (p < 0.05). In terms of the nutritional literacy variable, the direct effect of the health literacy variable on the microbiota awareness variable was 0.1707, and this was statistically significant at the 95% CI (p < 0.05). Nutrition literacy had a partial mediating role in the effect of health literacy on microbiota awareness (lower limit CI: 0.045; upper limit CI: 0.0894). The most accurate prediction of machine learning approaches to predict microbiota awareness was made with random forest with shapley additive explanations values, and the most important variable that should be in the model to predict the microbiota awareness variable was the nutrition literacy variable.</p><p><strong>Conclusion: </strong>Microbiota awareness increased as health literacy and nutrition literacy increased. In the machine learning approach prediction, the most important variables affecting microbiota awareness were health literacy and nutritional literacy. Longitudinal studies on microbiota awareness are recommended.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"54 5","pages":"938-948"},"PeriodicalIF":1.2,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11518376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of combined deep and superficial serratus anterior block with thoracic paravertebral block for postoperative pain in patients undergoing video-assisted thoracoscopic surgery.","authors":"Gülay Ülger, Musa Zengin, Onur Küçük, Ramazan Baldemir, Oya Kaybal, Mehtap Tunç, Hilal Sazak, Ali Alagöz","doi":"10.55730/1300-0144.5881","DOIUrl":"https://doi.org/10.55730/1300-0144.5881","url":null,"abstract":"<p><strong>Background/aim: </strong>Thoracic paravertebral block (TPVB) is a well-established procedure for the management of postoperative pain in patients undergoing video-assisted thoracic surgery (VATS). In recent years, there have been studies suggesting that fascial plane blocks may be an alternative to TPVB. The objective of our study was to determine the efficacy of combined deep and superficial serratus anterior block (C-SAPB) as an alternative to TPVB in the management of postoperative analgesia in VATS.</p><p><strong>Materials and methods: </strong>The patients were divided into two groups: the TPVB group and the C-SAPB group. Both groups were administered the same dose of local anesthetics. Multimodal analgesia was achieved for the groups. The primary outcome measure was visual analog scale (VAS) pain scores recorded within the first 48 h of the postoperative period in each group. The secondary outcomes were analgesic requirement, rescue analgesics, complications rate, and postoperative patient satisfaction.</p><p><strong>Results: </strong>Thirty patients with C-SAPB and 30 patients with TPVB were analysed. VAS rest and VAS coughing scores were similar between the groups (p > 0.05). Demographic and side effect conditions, total morphine use, additional analgesic needs, vital parameters, block procedure time, and patient satisfaction were also similar between the groups (p > 0.05). Additionally, although block application times were comparable, the time was slightly shorter in C-SAPB.</p><p><strong>Conclusion: </strong>Similar analgesic efficacy was observed between C-SAPB and TPVB. TPVB maintains its place among the first choices in VATS. The efficacy of C-SAPB is comparable to that of TPVB. While the duration of C-SAPB application is not a significant factor, the brief nature of the procedure and its straightforward administration suggest that it may be an effective method.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"54 5","pages":"1021-1032"},"PeriodicalIF":1.2,"publicationDate":"2024-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11518326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing depression, anxiety, stress, and occupational decision regret levels among resident physicians working at Ankara University Faculty of Medicine Hospital.","authors":"Emrah Emiral, Baris Ors, Nergis Cantürk","doi":"10.55730/1300-0144.5875","DOIUrl":"https://doi.org/10.55730/1300-0144.5875","url":null,"abstract":"<p><strong>Background/aim: </strong>Physicians work under high levels of stress due to factors such as excessive workload, emotional factors, and economic variables. This leads to various health problems such as depression, burnout, fatigue, and hopelessness, resulting in decreased interest in a medical career and an increase in career choice regret.</p><p><strong>Materials and methods: </strong>The study included 300 volunteer resident physicians from Ankara University Medical Faculty Hospital. The data for the research were collected using a survey form prepared by reviewing the literature. The survey consisted of three parts, which questioned the physicians' sociodemographic characteristics and professional choices, including the Depression Anxiety Stress Scale-Short Form (DASS-21) items and the Decision Regret Scale.</p><p><strong>Results: </strong>Of the physicians, 216 (72.0%) chose the medical faculty due to personal preference. The percentage of those who were not regretful about their career choice was 14.3% (n = 43). Those not regretful about their career choice had fewer years in the profession than the others. According to the categorical assessment of the DASS-21, 73.7% (n = 221) of the physicians had depressive symptoms ranging from mild to severe, 78.7% (n = 236) had anxiety symptoms ranging from mild to severe, and 57.7% (n = 173) had stress symptoms ranging from mild to severe.</p><p><strong>Conclusion: </strong>Mental health problems such as depression, anxiety, and stress were common among the resident physicians independent of their sociodemographic characteristics, and this was also associated with the level of career regret. Improving working conditions and personal benefits, addressing economic and other issues for physicians, ensuring their well-being, preventing the development of mental health problems, and early screening and rehabilitation for those affected not only have personal benefits but also contribute positively to job satisfaction, strengthen the patient-physician relationship, and have a significant impact on healthcare services.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"54 5","pages":"970-978"},"PeriodicalIF":1.2,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11518353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}