Turkish Journal of Medical Sciences最新文献

{"title":"Could ERAS protocols be integrated into the national Standards for Quality in Healthcare in Türkiye?","authors":"Mine Gürsaç Çelik, Adem Az, Mehmet Çetin, Neslihan Alkiş","doi":"10.55730/1300-0144.5975","DOIUrl":"10.55730/1300-0144.5975","url":null,"abstract":"","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"55 1","pages":"346-347"},"PeriodicalIF":1.2,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913487/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of empagliflozin on cyclophosphamide-induced neurotoxicity in rats without diabetes.","authors":"Şerife Ezgi Doğan, Şerife Mehlika Kuşkonmaz, Pınar Celepli, Mehmet Şenes, Sema Hücümenoğlu, Cavit Çulha","doi":"10.55730/1300-0144.5943","DOIUrl":"10.55730/1300-0144.5943","url":null,"abstract":"<p><strong>Background/aim: </strong>The objective of this study was to evaluate the effects of empagliflozin on cyclophosphamide-induced neurotoxicity in rats.</p><p><strong>Materials and methods: </strong>A total of 32 male Wistar rats were separated into 4 groups with 8 rats in each: the control group, cyclophosphamide group, empagliflozin group, and cyclophosphamide plus empagliflozin group. At the end of the experiment the rats' brains were removed for biochemical analysis of oxidative stress parameters (malondialdehyde, total sulfhydryl, total oxidant status, and total antioxidant capacity) and histopathological analysis.</p><p><strong>Results: </strong>Total sulfhydryl levels were increased in the empagliflozin group and empagliflozin and cyclophosphamide group compared to the cyclophosphamide group but histopathological findings were not improved. Furthermore, when empagliflozin treatment was used coupled with cyclophosphamide, necrosis was significantly higher.</p><p><strong>Conclusion: </strong>Empagliflozin has no protective effect on cyclophosphamide neurotoxicity, although it may have neurotoxic effects. Clarification of the possible neurotoxic/neuroprotective effects of empagliflozin would be beneficial for diabetic cancer patients who are receiving cyclophosphamide chemotherapy and empagliflozin together.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"55 1","pages":"65-71"},"PeriodicalIF":1.2,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thoracic disc herniations: diagnosis, surgical techniques, and complication insights.","authors":"Mehmet Denizhan Yurtluk, Aydın Sinan Apaydin, Hakan Kina, Khoi D Than","doi":"10.55730/1300-0144.5939","DOIUrl":"10.55730/1300-0144.5939","url":null,"abstract":"<p><p>Thoracic disc herniations (TDHs) are rare conditions, comprising 0.1% to 5% of all reported herniation cases, and affecting up to 1 in 1,000,000 individuals. The mid to lower thoracic spine, particularly between the T11 and T12 vertebrae, is most frequently affected and often associated with trauma. Conditions like Scheuermann's disease can predispose patients to TDHs. This study explores the clinical manifestations, diagnostic methods, surgical techniques, and complications associated with TDHs. Diagnosis relies on magnetic resonance imaging and computed tomography myelography to identify the level and nature of the herniation. Various surgical approaches, including posterolateral, lateral, and anterior, have been implemented, each with specific indications, advantages, and pitfalls. Complications range from lung-associated to neurological deterioration to dural breaches. Clinical presentation primarily includes thoracic back pain. Patients can present with significant neurological deficits depending on the herniation's characteristics, namely giant centrally located. Surgical intervention is indicated in cases of failed conservative treatment or acute trauma with significant cord compression. This review aimed to delve into the literature to provide insights into the clinical manifestations of TDHs, diagnosis, surgical techniques, and associated complications.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"55 1","pages":"17-23"},"PeriodicalIF":1.2,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New index for distinguishing between critical illness myopathy and neuromyopathy: CMAP amplitude/duration index.","authors":"Handan Uzunçakmak Uyanik, Fatma Gökçem Yildiz, Çağrı Mesut Temuçin","doi":"10.55730/1300-0144.5949","DOIUrl":"10.55730/1300-0144.5949","url":null,"abstract":"<p><strong>Background/aim: </strong>Critical illness-associated weakness is a common neuromuscular syndrome that may manifest as critical illness myopathy (CIM), critical illness polyneuropathy (CIP), or an overlapping syndrome known as critical illness polyneuromyopathy (CIPM). Distinguishing between these subtypes can be challenging due to technical issues, patient-related factors such as insufficient cooperation with needle electromyography (EMG) or edema, and the need for sophisticated, time-consuming electrophysiological methods and invasive procedures such as biopsy. This study aimed to contribute to the electrophysiological distinction between CIM and CIPM.</p><p><strong>Materials and methods: </strong>A new index was designed based on distal compound muscle action potential (CMAP) amplitude and negative peak duration values. Comparative and receiver operating characteristic curve analyses were performed on the parameters of patients with CIM and CIPM, as well as between patient groups and controls.</p><p><strong>Results: </strong>The median and ulnar CMAP index cut-off values for distinguishing between CIM and CIPM were determined to be 0.35 and 0.51, respectively. Values below these cut-off points support a diagnosis of CIPM while higher values indicate CIM. The best parameter for distinguishing both CIM and CIPM patients from healthy controls was the peroneal CMAP index, with a cut-off value of 0.45.</p><p><strong>Conclusion: </strong>The CMAP index can be easily calculated from CMAP values obtained during routine nerve conduction studies. This index may serve as a practical and guiding method for differentiating between CIM and CIPM, contributing to the electrophysiological diagnosis of critically ill patients, and particularly those with unreliable sensory nerve action potentials and needle EMG examinations.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"55 1","pages":"112-120"},"PeriodicalIF":1.2,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does CD47 expression have prognostic significance in classical Hodgkin lymphoma?","authors":"Aydan Kiliçarslan, Gülnaz Kurt Çevik, Mehmet Doğan, Ayşegül Aksoy Altinboğa, Funda Ceran, Gülşah Efecik, Mine Bakanay Öztürk","doi":"10.55730/1300-0144.5958","DOIUrl":"10.55730/1300-0144.5958","url":null,"abstract":"<p><strong>Background/aim: </strong>Hodgkin lymphoma (HL) is highly treatable, but new chemotherapy agents are needed for patients with progression or recurrence. CD47 regulates antiphagocytic activity by signaling through the signal regulatory protein alpha (SIRPα) pathway on macrophages. This study aimed to assess the expression of CD47 in HL cases and explore its relationship with Epstein-Barr virus (EBV) status and the International Prognostic Index (IPI).</p><p><strong>Materials and methods: </strong>One hundred twenty patients diagnosed with classical HL, characterized by the presence of Hodgkin and Reed-Sternberg (HRS) cells, and for whom IPI scores were available were included. Their demographic data and EBV status were retrieved from hospital records. CD47 immunohistochemical expression in HRS cells was evaluated based on its prevalence and intensity. The product of these two values was used to calculate the CD47 expression score.</p><p><strong>Results: </strong>Of the 120 patients, 76 (63.33%) were male and 44 (36.66%) were female, with an average age of 38.77 years. EBV ISH test results were available for 93 patients, of which 48 (51.61%) were positive. CD47 expression was 67% on average, and patients were categorized based on CD47 expression scores of ≤6 and >6 and IPI scores of ≤2 and >2. No significant relationship was found between CD47 expression score and age (p: 0.990), sex (p: 0.086), EBV status (p: 0.374), or IPI score (p: 0.805). However, higher IPI scores were significantly associated with increased EBV positivity (p: 0.041).</p><p><strong>Conclusion: </strong>CD47 was widely expressed, but no significant relationship with clinical parameters was observed. Further studies are required to validate its role as a biomarker.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"55 1","pages":"203-208"},"PeriodicalIF":1.2,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between uncoupling protein 1 (UCP1) levels and psoriasis.","authors":"Fikret Akyürek, Fatma Tuncez Akyürek, Fatma Şengül Bağ","doi":"10.55730/1300-0144.5960","DOIUrl":"10.55730/1300-0144.5960","url":null,"abstract":"<p><strong>Background/aim: </strong>Psoriasis is a common chronic autoimmune skin disease. Comorbidities increase the mortality risk of the disease. The aim of this study was to investigate the changes in uncoupling protein 1 (UCP1) level in psoriasis patients and evaluate its possible role in the pathogenesis of the disease, focusing on disease severity (Psoriasis Area and Severity Index), dyslipidemia, inflammation, and cardiovascular risk.</p><p><strong>Materials and methods: </strong>This study included 30 psoriasis patients and 30 healthy individuals as a control group. Serum UCP1 was measured using an ELISA test kit. The laboratory results of psoriasis patients and healthy controls were compared.</p><p><strong>Results: </strong>UCP1 level was a significant candidate marker for the prediction of psoriatic disease (AUC: 0.708, 95% CI: 0.577-0.819, p = 0.002) with sensitivity of 66.67%, specificity of 76.67%, negative predictive value of 69.7%, and positive predictive value of 74.1%. Simple logistic regression analysis showed that an individual with a UCP1 value below 7.561 had a 73% lower probability (OR: 0.27, 95% CI: 0.08-0.94, p = 0.039) of developing psoriasis than an individual with a UCP1 value above 7.561. Among the biochemical parameters, the high-sensitivity C-reactive protein and triglyceride levels of the patients were significantly higher compared to those of the healthy controls while their high-density lipoprotein levels were lower.</p><p><strong>Conclusion: </strong>According to the sensitivity (66.67%) and specificity (76.67%) of UCP1, it may be a valuable candidate marker in the diagnosis of psoriasis patients in symptomatic and asymptomatic phases. Further work is needed to substantiate these findings.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"55 1","pages":"215-222"},"PeriodicalIF":1.2,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic mutations and prognostic indicators in differentiated thyroid cancer: a molecular perspective.","authors":"Halim Özçevik, Müge Öner Tamam, Gündüzalp Buğrahan Babacan, Selma Şengiz Erhan, Merve Nur Acar Tayyar, Biray Ertürk","doi":"10.55730/1300-0144.5944","DOIUrl":"10.55730/1300-0144.5944","url":null,"abstract":"<p><strong>Background/aim: </strong>The aim of this study was to investigate the relationship between the presence of the BRAF, HRAS, NRAS, and KRAS gene mutations and the development of dedifferentiation (iodine-refractory disease) and extrathyroidal disease in patients with differentiated thyroid carcinoma (DTC).</p><p><strong>Materials and methods: </strong>The patient group included 77 adults classified as intermediate or high-risk according to the American Thyroid Association's 2015 guidelines who underwent total thyroidectomy followed by radioiodine I-131 (RAI) therapy between June 2014 and December 2022. Clinical data were collected via the hospital information system, including the number of surgeries and RAI treatments and the levels of thyroglobulin (Tg), anti-thyroglobulin, and thyroid-stimulating hormone. The histopathological subtypes of DTC were reevaluated, and mutation analyses of the BRAF, KRAS, NRAS, and HRAS genes were performed using real-time polymerase chain reaction (PCR). Statistical analyses were conducted using Medcalc software, with p < 0.05 considered significant.</p><p><strong>Results: </strong>Of the 77 patients, most had classical papillary thyroid carcinoma, while others represented various subtypes. No mutations were found in BRAF K601E/V600_K601, KRAS G12x-G13D, or NRAS G12-G13; however, NRAS Q61x was found in one patient, HRAS Q61x in 12, and BRAFV600E/Ec in 36. A significant relationship was observed between HRAS Q61x mutation and disease response, alongside a significant association between gene mutations and iodine-refractory disease development (p = 0.0004). A ROC curve analysis indicated a 49.2 ng/mL threshold for Tg with 75% sensitivity and 94.1% specificity.</p><p><strong>Conclusion: </strong>The findings suggest that the HRAS Q61x gene mutation is significantly associated with iodine-resistant disease. It may serve as a prognostic biomarker in early-stage thyroid cancer and aid in disease monitoring in metastatic patients.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"55 1","pages":"72-81"},"PeriodicalIF":1.2,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new formula for predicting the actual volume of parathyroid adenoma in patients with primary hyperparathyroidism.","authors":"İbrahim Kilinç, Mustafa Oruç, Serap Ulusoy, Ali Coşkun, Mehmet Kiliç","doi":"10.55730/1300-0144.5945","DOIUrl":"10.55730/1300-0144.5945","url":null,"abstract":"<p><strong>Background/aim: </strong>Knowing adenoma volume in patients with primary hyperparathyroidism is useful for surgeons during parathyroidectomy. The primary aim of our study was to identify the most accurate method for calculating adenoma volume. Our secondary aim was to determine the relationship between adenoma volume and preoperative biochemical parameters (parathyroid hormone [PTH] and calcium levels).</p><p><strong>Material and methods: </strong>The medical histories of 75 patients who underwent surgery for a single parathyroid adenoma were prospectively collected. After excision, the adenomas were placed in water-filled syringes, and their actual volume was determined according to the amount of water displaced. The radiological volume of the adenomas was calculated using the ellipsoid body formula according to the ultrasonographic dimensions. The PTH and calcium levels of the patients were retrieved from the patients' hospital records.</p><p><strong>Results: </strong>The calculated radiological volumes correlated with the actual adenoma volumes, but there were significant differences between the two measurements. A new formula was developed based on actual volumes and radiological volumes. A positive correlation was found between the adenoma volumes and the preoperative PTH and calcium levels.</p><p><strong>Conclusion: </strong>Adenoma volume calculated using a mathematical formula based on ultrasound measurements does not accurately reflect the actual volume. Higher preoperative calcium and PTH levels are associated with larger adenoma size.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"55 1","pages":"82-86"},"PeriodicalIF":1.2,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outbreak of bacteremia caused by <i>Ralstonia insidiosa</i> isolated from a contaminated blood gas syringe.","authors":"Elif Ayça Şahin, Özge Özgen Top, Pınar Aysert Yildiz, Elif Seren Tanriverdi, Hasan Selçuk Özger, Barış Otlu, Özlem Güzel Tunçcan, Murat Dizbay, Ayşe Kalkanci, Kayhan Çağlar","doi":"10.55730/1300-0144.5967","DOIUrl":"10.55730/1300-0144.5967","url":null,"abstract":"<p><strong>Background/aim: </strong><i>Ralstonia</i> species are opportunistic, waterborne microorganisms known for their ability to survive and proliferate in a wide range of water-based environments. They can contaminate solutions used for patient care and cause hospital outbreaks due to contaminated solutions. The aim of this study was to investigate the source and clonal relationship of <i>Ralstonia insidiosa</i> bacteremia detected in 28 patients between August and December 2021, as part of an unusual outbreak.</p><p><strong>Materials and methods: </strong>Active prospective surveillance studies were conducted, and environmental samples, including saline, antiseptic, and antibiotic solutions, injectors, arterial blood gas syringes, tap water, and hand soap, were collected from wards to determine the source of the outbreak. An arbitrary-primed polymerase chain reaction (AP-PCR) genotyping method was used to determine the clonal relationship between the isolates.</p><p><strong>Results: </strong>All the samples were cultured, and <i>R. insidiosa</i> was isolated from arterial blood gas syringes with the same location and time-based identifier (LOT number). All the arterial blood gas syringes were recalled from the hospital departments and sent back to the manufacturer. The outbreak was reported to the national health authorities. Clonal analysis between isolates from the patients and the blood gas syringes was performed using AP-PCR. It was observed that the <i>R. insidiosa</i> isolates were monoclonal and identical.</p><p><strong>Conclusion: </strong>It was concluded that these contaminated arterial blood gas syringes caused the <i>R. insidiosa</i> bacteremia, especially in immunocompromised patients.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"55 1","pages":"265-270"},"PeriodicalIF":1.2,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of ivermectin on nerve regeneration following sciatic injury in mice: the consequences of dietary high fructose.","authors":"Ezgi Deniz Arikan, Barışcan Çimen, Ayşe Ece Gezen Yilmaz, Elif Akaydin, Berkay Alpay, Deniz Ekin Erbaş, Erblina Nikshiqi, Sevda F Müftüoğlu, Yıldırım Sara","doi":"10.55730/1300-0144.5971","DOIUrl":"10.55730/1300-0144.5971","url":null,"abstract":"<p><strong>Background/aim: </strong>Peripheral nerve injuries (PNIs) are debilitating disorders affecting predominantly the younger generation, often leading to significant disabilities. Current treatment strategies are inadequate for addressing the complex nature of these injuries. Peripheral nerve healing and functional recovery are crucial components of both pathophysiology and therapeutic approaches. High fructose corn syrup (HFCS) is a sweetener frequently used in several beverages and foods. It is associated with several metabolic disturbances including insulin resistance and may impair nerve healing. This study investigated the therapeutic role of ivermectin on nerve regeneration following sciatic nerve injury and evaluated motor and sensorial functions together with histopathological evaluation. Additionally, we aimed to compare nerve healing between animals that consume HFCS and those that do not.</p><p><strong>Materials and methods: </strong>Forty-eight male Swiss albino mice were randomly divided into six groups, with three consuming HFCS-42 (11% v/v) and the other three regular tap water for 8 weeks. On day 28, sciatic nerve injury (SNI) was caused in all groups. Ivermectin (1 mg/kg) or gabapentin (30 mg/kg) treatments were administered to selected groups. Body weight, blood glucose, motor function (rotarod, open field test), and thermal-mechanical sensorial functions were assessed weekly. Finally, insulin levels were measured and histopathological samples were taken.</p><p><strong>Results: </strong>Eight weeks of HFCS consumption impaired mechanical and thermal sensory functions and resulted in histopathologically poor nerve repair. Ivermectin resulted in improved sensorial and faster motor function recovery in the HFCS groups. Elevated plasma insulin levels/HOMA-IR values were diminished by ivermectin in the HFCS groups. In the ivermectin non-HFCS group, histopathology revealed accelerated healing and higher scores in total. Ivermectin also ameliorated mechanical sensation loss after SNI along with cold sensation.</p><p><strong>Conclusion: </strong>Ivermectin accelerated sensorial and motor nerve recovery, resulting in faster nerve healing alongside improved insulin resistance, suggesting it might serve as a potential foundation for developing a new treatment for nerve regeneration after injury.</p>","PeriodicalId":23361,"journal":{"name":"Turkish Journal of Medical Sciences","volume":"55 1","pages":"299-312"},"PeriodicalIF":1.2,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}