Turkish translation, validity, and reliability of the European organization for research and treatment of cancer quality of life-high dose chemotherapy29 in patients undergone hematopoietic stem cell transplantation.

IF 1 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Turkish Journal of Medical Sciences Pub Date : 2025-04-17 eCollection Date: 2025-01-01 DOI:10.55730/1300-0144.6001

Vesile Yildiz Kabak, Sevilay Karahan, Elifcan Aladağ Karakulak, Tülin Düger, Songül Atasavun Uysal, Fulya Ipek Erdem, Hakan Göker

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Abstract

Background/aim: Our aim was to investigate psychometric properties of the Turkish version of the European organization for research and treatment of cancer quality of life-high dose chemotherapy29 (EORTC QLQ-HDC29) in patients treated with hematopoietic stem cell transplantation (HSCT).

Materials and methods: Patients between the ages of 18 and 65 years and undergone HSCT were included. The European organization for research and treatment of cancer quality of life questionnaire-cancer30 the Eastern cooperative oncology group performance score, and the functional assessment of cancer therapy-bone marrow transplant were used to determine convergent validity. Reliability was assessed through the calculation of Cronbach's alpha and intra-class correlation coefficient (ICC) values.

Results: Totally 151 patients were included. The convergent validity analysis between the EORTC QLQ-HDC29 and the other variables revealed significant, low to strong correlations (p < 0.05). The test-retest reliability of the questionnaire was excellent (ICC values ranged from 0.886 to 1.000). The internal consistency values were acceptable except for the "Worries/Anxiety" and "Inpatient Issues" scales (ranged from 0.175 to 0.985).

Conclusion: The reliability and validity of Turkish version of the EORTC QLQ-HDC29 was feasible and acceptable in patients treated with HSCT. Further research is required to ascertain the psychometric properties of the EORTC QLQ-HD29.

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欧洲研究和治疗癌症生活质量组织的土耳其语翻译、有效性和可靠性——造血干细胞移植患者的高剂量化疗y29。

背景/目的：我们的目的是研究土耳其版的欧洲癌症生活质量研究和治疗组织高剂量化疗y29 （EORTC QLQ-HDC29）在接受造血干细胞移植（HSCT）治疗患者中的心理测量特性。材料和方法：纳入年龄在18 ~ 65岁之间并接受过HSCT的患者。采用欧洲癌症研究与治疗组织生活质量问卷-cancer30、东方合作肿瘤组绩效评分和肿瘤治疗-骨髓移植功能评估来确定收敛效度。通过计算Cronbach's alpha和类内相关系数（ICC）值来评估信度。结果：共纳入151例患者。EORTC QLQ-HDC29与其他变量的收敛效度分析显示显著的、低到强的相关性（p < 0.05）。问卷的重测信度极好（ICC值为0.886 ~ 1.000）。除“担忧/焦虑”和“住院问题”量表（范围为0.175 ~ 0.985）外，内部一致性值均可接受。结论：土耳其版EORTC QLQ-HDC29的信度和效度在接受HSCT治疗的患者中是可行和可接受的。需要进一步的研究来确定EORTC QLQ-HD29的心理测量特性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Turkish Journal of Medical Sciences 医学-医学：内科

CiteScore

4.60

自引率

4.30%

发文量

143

审稿时长

3-8 weeks

期刊介绍： Turkish Journal of Medical sciences is a peer-reviewed comprehensive resource that provides critical up-to-date information on the broad spectrum of general medical sciences. The Journal intended to publish original medical scientific papers regarding the priority based on the prominence, significance, and timeliness of the findings. However since the audience of the Journal is not limited to any subspeciality in a wide variety of medical disciplines, the papers focusing on the technical details of a given medical subspeciality may not be evaluated for publication.