Turkish journal of anaesthesiology and reanimation最新文献

{"title":"The Potential Renoprotective Effect of Sugammadex in Renal Ischemia-reperfusion Injury.","authors":"Vildan Kölükçü, Mehtap Gürler Balta, Ahmet Tuğrul Şahin, Ali Genç, Velid Unsal, Fatih Fırat, Fikret Gevrek, Asiye Yancı, Ahmet Burak Gürpınar","doi":"10.4274/TJAR.2025.251887","DOIUrl":"10.4274/TJAR.2025.251887","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to evaluate the effectiveness of sugammadex on renal tissue for against ischemia-reperfusion injury.</p><p><strong>Methods: </strong>Twenty-one Wistar albino strain female rats were divided into three groups. The first group functioned as the control cohort for comparison. In Groups 2 and 3, a renal ischemia-reperfusion model was established. Moreover, following the cessation of ischemia, the rats in Group 3 were intravenously administered sugammadex at a dose of 4 mg kg^-1. Blood and tissue samples were subsequently collected for analysis.</p><p><strong>Results: </strong>Biochemical analyses revealed a notable increase in the enzymatic activities of glutathione peroxidase and superoxide dismutase in Group 3 relative to Group 2 (<i>P</i> < 0.001 and <i>P</i>=0.015, respectively). Additionally, the concentration of malondialdehyde was found to be significantly reduced in Group 3 relative to Group 2 (<i>P</i>=0.004). Group 3 exhibited a substantial decrease in tumor necrosis factor-alpha, interleukin 6, and interleukin 1 beta levels when compared to Group 2 (<i>P</i>=0.021, <i>P</i>=0.006, and <i>P</i>=0.016 respectively). Group 2 exhibited the highest concentrations of neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 (<i>P</i> < 0.001 and <i>P</i>=0.015, respectively). Similarly, the histopathologic tissue damage was the most prominent in Group 2 (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Sugammadex plays a protective role against ischaemia-reperfusion injury in renal tissue.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Application of Regional Anaesthesia in Türkiye: National Survey Study.","authors":"Elvin Kanat, Zeynep Çağıran, Nezih Sertöz","doi":"10.4274/TJAR.2025.251900","DOIUrl":"https://doi.org/10.4274/TJAR.2025.251900","url":null,"abstract":"<p><strong>Objective: </strong>This study was designed to determine why anaesthesiologists working in various institutions in our country prefer current regional anaesthesia methods and to evaluate the use and prevalence of ultrasonography in these methods.</p><p><strong>Methods: </strong>A questionnaire created on SurveyMonkey.com was sent electronically or face-to-face to anaesthesiology and reanimation physicians working in different provinces of our country, and they were asked to fill it out. The survey was intended to be administered to at least 200 volunteer anaesthesiologists. The questionnaire consisted of 34 questions, including demographic characteristics, neuraxial block and peripheral nerve block (PNB) applications, drug choices, preferences in paediatric cases, training, and safety measures.</p><p><strong>Results: </strong>A total of 215 anaesthesiologists participated in our questionnaire. 39.2% were working in a university hospital, and 38.2% were working in a training and research hospital. PNB training was received by 89.2% of the participants during specialty training. For analgesic purposes, the interscalene block was preferred for shoulder surgery (57.4%), the axillary block for elbow, forearm, and hand surgery (49.8%), the erector spinae plane block for thoracic surgery (33.8%), and the transverse abdominis and rectus block for open abdominal surgery (51.5%).</p><p><strong>Conclusion: </strong>Regional anaesthesia is an essential part of multimodal analgesia and is used both as an anaesthetic and analgesic in routine practice. In recent years, many new techniques have been utilized as a result of advancements. However, for these to be implemented in practice, up-to-date information should be closely followed, and anaesthetists should be supported in terms of training and equipment.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Preoperative Duration of Fasting on the Intravascular Volume Status of Children Older than 5 Years of Age: A Prospective, Observational Study.","authors":"Beliz Bilgili, Tümay Umuroğlu","doi":"10.4274/TJAR.2025.251934","DOIUrl":"https://doi.org/10.4274/TJAR.2025.251934","url":null,"abstract":"<p><strong>Objective: </strong>Preoperative fasting is a common practice aiming to reduce the risk of pulmonary aspiration during anaesthesia. It is advised to avoid fasting times longer than 6 hours in all children, whenever possible. Prolonged fasting can be uncomfortable for children and may lead to dehydration and other negative outcomes. The primary outcome of the study was the relationship between preoperative duration of fasting and cardiac index (CI) variability, used as a surrogate for intravascular volume status after the induction of anaesthesia, in paediatric patients undergoing surgery.</p><p><strong>Methods: </strong>Prospective, observational study that included patients over 5 years of age, scheduled for surgery. Passive leg-raising-induced CI variability was evaluated for fluid responsiveness and intravascular volume after anaesthesia induction. Patients were termed fluid responders (Rs) if an increase in CI of >10% was obtained after passive leg raising, and non-responders (NRs) if the CI variability was <10%. CI and aortic peak velocity (V_peak) were measured through the suprasternal notch via an ultrasonic cardiac output monitor.</p><p><strong>Results: </strong>There were 32 Rs and 53 (NRs). The mean duration of fasting for Rs was 11.53±2.61, while NR had a mean duration of fasting of 10.6±2.93 hours, showing an insignificant difference. Aortic V_peak change was significantly higher in Rs (0.24±0.17) compared to NRs (0.03±0.13) (<i>P</i> < 0.001). Duration of fasting showed no significant correlation with CI variability and peak aortic velocity.</p><p><strong>Conclusion: </strong>With this study method, it was observed that preoperative fasting time had no effect on intraoperative intravascular volume.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Clinical and Radiological Comparison of Intradiscal Ozone and Ozone + PRP Therapy Results in Patients with Intervertebral Disc Degeneration.","authors":"Gülseli Berivan Sezen, Osman Boyalı, Burak Karip, Selman Aktaş, Eyüp Can Savrunlu, Mourat Chasan, Necati Kaplan, Erdinç Civelek, Serdar Kabataş","doi":"10.4274/TJAR.2025.241831","DOIUrl":"https://doi.org/10.4274/TJAR.2025.241831","url":null,"abstract":"<p><strong>Objective: </strong>This retrospective study aimed to evaluate and compare the clinical efficacy of intradiscal ozone therapy (OT) against a combination therapy of ozone and platelet-rich plasma (PRP) in patients diagnosed with intervertebral disc degeneration (IVDD).</p><p><strong>Methods: </strong>The study included a cohort of 50 patients, divided equally into two groups of 25, who received either intradiscal OT or ozone + PRP combination therapy between February 2022 and February 2023. The sample comprised 20 females and 30 males, with ages ranging from 19 to 76 years (mean age 48.8). Pain intensity was measured using the visual analog scale (VAS), while disability levels were assessed using the oswestry disability index (ODI) prior to treatment and at 1, 3, and 6 months post-treatment. Additionally, lumbar magnetic resonance imaging was conducted at the 3-month mark post-treatment, with evaluations based on the Pfirrmann disc degeneration classification.</p><p><strong>Results: </strong>Significant improvement in both VAS and ODI scores was observed in both treatment groups (<i>P</i> < 0.001). The ozone + PRP combination therapy group exhibited no statistically significant difference in VAS and ODI scores compared to the ozone-only group (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>Intradiscal OT and the ozone + PRP combination therapy represent effective minimally invasive treatment options for patients suffering from IVDD, yielding substantial clinical benefits with minimal side effects. That is why it is suggested as a potential preferred therapeutic approach prior to the consideration of surgical interventions.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of microRNA in Anaesthetics-induced Brain Injury: A Narrative Review.","authors":"Elvan Öçmen, Bilge Karaçiçek, Burak İbrahim Arıöz, Hale Aksu, Şermin Genç","doi":"10.4274/TJAR.2025.241739","DOIUrl":"https://doi.org/10.4274/TJAR.2025.241739","url":null,"abstract":"<p><p>Anaesthetics are commonly used agents during medical interventions and surgeries. Exposure to anaesthetic agents in late intrauterine life or early childhood may cause neurodegeneration in developing brains. Neuroapoptosis and neural inhibition provided by several mechanisms and microRNAs (miRNAs) have crucial roles in this milieu. miRNAs have critical roles in response to anaesthetic exposure. Through this review, we performed a systematic search of the PubMed database for studies on the role of anaesthetics in the brain and their relation with miRNAs. The terms \"anesthetic\", \"miRNA\", and \"brain\" were searched. Here we summarized the roles and interactions of miRNAs under exposure to anaesthetics <i>in vivo</i> and <i>in vitro</i> studies. Anaesthetic agents studied included sevoflurane, isoflurane, ketamine, and propofol. Many microRNAs were identified to have regulatory roles in anaesthesia-induced neurotoxicity. The literature study supports the idea that miRNAs play crucial functions in neuroprotection and neurotoxicity in anaesthesia administration. The exact role and implication of miRNA in anaesthesia neurotoxicity needs to be elucidated to gain more knowledge about the area. Several gaps in knowledge should be filled by conducting basic, clinical, and translational analyses in the future to decipher the definite role of miRNAs and their functions in the context of anaesthesia-induced neurotoxicity.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Artificial Intelligence Be Successful as an Anaesthesiology and Reanimation Resident?","authors":"Gökçen Kültüroğlu, Yusuf Özgüner, Savaş Altınsoy, Seyyid Furkan Kına, Ela Erdem Hıdıroğlu, Jülide Ergil","doi":"10.4274/TJAR.2025.251927","DOIUrl":"https://doi.org/10.4274/TJAR.2025.251927","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to compare the performance of artificial intelligence (AI) chatbot ChatGPT with anaesthesiology and reanimation residents at a major hospital in an exam modelled after the European Diploma in Anaesthesiology and Intensive Care Part I.</p><p><strong>Methods: </strong>The annual training exam for residents was administered electronically. One day prior to this, the same questions were posed to an AI language model. During the analysis, the residents were divided into two groups based on their training duration (less than 24 months: Group J; 24 months or more: Group S). Two books and four guides were used as references in the preparation of a 100-question multiple-choice exam, with each correct answer awarded one point.</p><p><strong>Results: </strong>The median exam score among all participants was 70 [interquartile range (IQR) 67-73] out of 100. ChatGPT correctly answered 71 questions. Group J had a median exam score of 67 (IQR 65.25-69), while Group S scored 73 (IQR 70-75) (<i>P</i> < 0.001). Residents with less than 24 months of training performed significantly worse across all subtopics compared to those with more extensive training (<i>P</i> < 0.05). When ranked within the groups, ChatGPT placed eighth in Group J and 47^th in Group S.</p><p><strong>Conclusion: </strong>ChatGPT exhibited a performance comparable to that of a resident in an exam centred on anaesthesiology and critical care. We suggest that by tailoring an AI model like ChatGPT in anaesthesiology and resuscitation, exam performance could be enhanced, paving the way for its development as a valuable tool in medical education.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Prone Position on Right Ventricular Functions in CARDS: Is Survival Predictable when Evaluated Through Transesophageal Echocardiography?","authors":"Dicle Birtane, Zafer Çukurova, Sinan Aşar, Damla Özmen, Gökhan Sertcakacılar, Fatma Nihan Çağlar Turhan","doi":"10.4274/TJAR.2025.241830","DOIUrl":"10.4274/TJAR.2025.241830","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the cardiopulmonary effect during prone position (PP) on right ventricular (RV) recovery in coronavirus disease-2019 related acute respiratory distress syndrome (C-ARDS) through transesophageal echocardiography (TEE).</p><p><strong>Methods: </strong>This prospective study included 30 moderate-to-severe C-ARDS patients who were treated with PP in the first 48 h of invasive mechanical ventilation support. It was evaluated with TEE three times: before PP (T₀f), the first hour of PP (T₁), and the first hour of returning to the supine position (T₀ + 24 h) (T₂) after 23 hours of PP treatment. RV end-diastolic area/left ventricular (LV) end-diastolic area (RVEDA/LVEDA), tricuspid annular plane systolic excursion (TAPSE) and LV end-systolic eccentricity index were preferred RV evaluations as primary outcomes. Pulmonary effects of PP were evaluated as a secondary outcome, including PaO₂/FiO₂, driving pressure (dP), static compliance (Cstat), mechanical ventilation parameters, and their association with 28-day survival. Tissue DO₂ was examined as a secondary outcome, and it was calculated using the measured cardiac output through TEE.</p><p><strong>Results: </strong>With the cardiopulmonary effect of PP, the decrease in RVEDA/LVEDA, the increase in TAPSE, PaO₂/FiO₂, and Cstat, and the decrease in dP were statistically significant (<i>P</i> < 0.05). The Cstat value associated with 28-day survival showed decreased mortality for each unit increase. The Cstat cut-off value, which was statistically significant for survival, was 37.</p><p><strong>Conclusion: </strong>PP can improve RV recovery and oxygenation, but it isn't always accompanied by increased survival. An increase in the Cstat may improve survival without the development of RV dysfunction while maintaining heart-lung interaction.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":"53 2","pages":"53-61"},"PeriodicalIF":0.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative Practice Patterns of Anaesthesiologists Surrounding Glucagon-Like Peptide-1 (GLP-1) Agonist Medications.","authors":"Meghan Brennan, Sabrina H Han, Kyle Ockerman, Sonia D Mehta, Heather J Furnas, Frederik Heath, Patricia Mars, Audrey Klenke, Sarah C Sorice-Virk","doi":"10.4274/TJAR.2025.241653","DOIUrl":"10.4274/TJAR.2025.241653","url":null,"abstract":"<p><strong>Objective: </strong>Aspiration of gastric contents during induction of anaesthesia is a rare but well-recognized complication with high morbidity and mortality risk. Patients at highest risk include those with full stomachs, diabetes, hiatal hernias, gastrointestinal obstructions, severe gastroesophageal reflux, and known delayed gastric emptying. Recently, the use of glucagon-like peptide-1 (GLP-1) agonists has expanded rapidly, including their application in cosmetic weight loss. This drug class suppresses glucagon release after meals, thereby delaying gastric emptying over an undefined duration. For patients taking these medications in the perioperative period, the effect on overall aspiration risk is unknown. This survey details the current practice pattern of anaesthesiologists regarding GLP-1 agonists.</p><p><strong>Methods: </strong>An IRB-approved 30-question, uncompensated survey was distributed to 30,096 self-reported actively practicing United States members of the American Society of Anesthesiologists (ASA). The survey collected demographic information, practice information, and included questions about the management of patients taking GLP-1 agonists. To ensure participant confidentiality, no identifiable information was collected.</p><p><strong>Results: </strong>The survey response rate was 5.98%, with 1,801 surveys returned. Ninety-seven percent of respondents indicated familiarity with GLP-1 agonists, and eighty-one percent indicated they had not personally witnessed complications in patients taking GLP-1 agonists. Most respondents indicated perioperative aspiration as the largest concern and the most commonly reported witnessed complication. 62% reported having \"some\" to \"a lot\" of experience providing anaesthesia to patients taking these medications. Most respondents reported NPO guidelines consistent with current ASA practice guidelines.</p><p><strong>Conclusion: </strong>The majority of anaesthesiologists report perioperative aspiration as their highest concern for patients taking this class of medications.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":"53 2","pages":"42-52"},"PeriodicalIF":0.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Hybrid Technique Using Video Laryngoscope-assisted Flexible Bronchoscopy to Facilitate Endotracheal Intubation in Children with Anticipated Difficult Airway: A Case Series.","authors":"K Gunasekaran, Reesha Joshi, Pradeep Karunagaran, V S G Yachendra","doi":"10.4274/TJAR.2024.241587","DOIUrl":"10.4274/TJAR.2024.241587","url":null,"abstract":"<p><p>We present a case series using a hybrid technique of video laryngoscope-assisted flexible bronchoscopy to facilitate endotracheal intubation in children with anticipated difficult airway. This series describes the management of difficult airways in four paediatric cases using the hybrid technique: two cases of Apert syndrome scheduled for cranial remodelling with orbito-facial advancement, one case of an incomplete cleft palate and retrognathia scheduled for palatoplasty, and another case of Parry Romberg syndrome scheduled for a reconstructive procedure. This case series aims to highlight the value of the hybrid technique as a safe and effective intubation modality in paediatric difficult airways.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":"53 2","pages":"77-81"},"PeriodicalIF":0.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endotracheal Tube Size Estimation in Paediatric Patients: A Head-to-head Comparison of Accuracy Between Ultrasonography and Age-based Formula.","authors":"Archan Jayantbhai Bhut, Kalyani Nilesh Patil, Sarita Swami","doi":"10.4274/TJAR.2025.241822","DOIUrl":"10.4274/TJAR.2025.241822","url":null,"abstract":"<p><strong>Objective: </strong>In the paediatric population, the selection of an appropriately sized endotracheal tube (ETT) is extremely important not only to ensure adequate ventilation but also to avoid post-extubation stridor and stenosis. Conventionally, formulas based on age, height, or weight are used to determine the most appropriate size. In this study, we compared ultrasonography (USG) and age-based formula for predicting the best microcuff ETT size in paediatric patients aged 1-5 years.</p><p><strong>Methods: </strong>One hundred eighteen patients, aged 1 to 5 years, with American Society of Anesthesiologists, classifications of I or II, were included. After standard general anaesthesia protocols, the subglottic diameter was assessed by USG. Intubation was performed using ETT size according to age-based formula. The best clinical fit was determined after the leak test. The internal and external diameters of the ETTs were predicted by both methods and correlated with the best-fit ETT sizes used during the procedures using Pearson's correlation. Cohen's kappa was used for statistical agreement between two methods.</p><p><strong>Results: </strong>USG had a significantly higher correlation with the best-fit model as compared to the age-based formula, with 99.2% and 77.1% agreement rates. The best-fit ETT showed a better correlation with the USG-guided estimate (r = 0.994, <i>P</i> < 0.001). The Cohen's Kappa value of 0.986 showed a statistically significantly higher agreement between USG-guided estimate and best-fit ETT.</p><p><strong>Conclusion: </strong>USG-guided estimation of subglottic diameter is a better predictor for optimally sized microcuff ETT than the age-based formula in the paediatric age group of 1-5 years. 22% of tube changes could have been prevented with ultrasound-guidance as a primary approach for estimating ETT size.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":"53 2","pages":"69-76"},"PeriodicalIF":0.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}