Turkish journal of anaesthesiology and reanimation最新文献

{"title":"The Role of microRNA in Anaesthetics-induced Brain Injury: A Narrative Review.","authors":"Elvan Öçmen, Bilge Karaçiçek, Burak İbrahim Arıöz, Hale Aksu, Şermin Genç","doi":"10.4274/TJAR.2025.241739","DOIUrl":"https://doi.org/10.4274/TJAR.2025.241739","url":null,"abstract":"<p><p>Anaesthetics are commonly used agents during medical interventions and surgeries. Exposure to anaesthetic agents in late intrauterine life or early childhood may cause neurodegeneration in developing brains. Neuroapoptosis and neural inhibition provided by several mechanisms and microRNAs (miRNAs) have crucial roles in this milieu. miRNAs have critical roles in response to anaesthetic exposure. Through this review, we performed a systematic search of the PubMed database for studies on the role of anaesthetics in the brain and their relation with miRNAs. The terms \"anesthetic\", \"miRNA\", and \"brain\" were searched. Here we summarized the roles and interactions of miRNAs under exposure to anaesthetics <i>in vivo</i> and <i>in vitro</i> studies. Anaesthetic agents studied included sevoflurane, isoflurane, ketamine, and propofol. Many microRNAs were identified to have regulatory roles in anaesthesia-induced neurotoxicity. The literature study supports the idea that miRNAs play crucial functions in neuroprotection and neurotoxicity in anaesthesia administration. The exact role and implication of miRNA in anaesthesia neurotoxicity needs to be elucidated to gain more knowledge about the area. Several gaps in knowledge should be filled by conducting basic, clinical, and translational analyses in the future to decipher the definite role of miRNAs and their functions in the context of anaesthesia-induced neurotoxicity.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Artificial Intelligence Be Successful as an Anaesthesiology and Reanimation Resident?","authors":"Gökçen Kültüroğlu, Yusuf Özgüner, Savaş Altınsoy, Seyyid Furkan Kına, Ela Erdem Hıdıroğlu, Jülide Ergil","doi":"10.4274/TJAR.2025.251927","DOIUrl":"https://doi.org/10.4274/TJAR.2025.251927","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to compare the performance of artificial intelligence (AI) chatbot ChatGPT with anaesthesiology and reanimation residents at a major hospital in an exam modelled after the European Diploma in Anaesthesiology and Intensive Care Part I.</p><p><strong>Methods: </strong>The annual training exam for residents was administered electronically. One day prior to this, the same questions were posed to an AI language model. During the analysis, the residents were divided into two groups based on their training duration (less than 24 months: Group J; 24 months or more: Group S). Two books and four guides were used as references in the preparation of a 100-question multiple-choice exam, with each correct answer awarded one point.</p><p><strong>Results: </strong>The median exam score among all participants was 70 [interquartile range (IQR) 67-73] out of 100. ChatGPT correctly answered 71 questions. Group J had a median exam score of 67 (IQR 65.25-69), while Group S scored 73 (IQR 70-75) (<i>P</i> < 0.001). Residents with less than 24 months of training performed significantly worse across all subtopics compared to those with more extensive training (<i>P</i> < 0.05). When ranked within the groups, ChatGPT placed eighth in Group J and 47^th in Group S.</p><p><strong>Conclusion: </strong>ChatGPT exhibited a performance comparable to that of a resident in an exam centred on anaesthesiology and critical care. We suggest that by tailoring an AI model like ChatGPT in anaesthesiology and resuscitation, exam performance could be enhanced, paving the way for its development as a valuable tool in medical education.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Prone Position on Right Ventricular Functions in CARDS: Is Survival Predictable when Evaluated Through Transesophageal Echocardiography?","authors":"Dicle Birtane, Zafer Çukurova, Sinan Aşar, Damla Özmen, Gökhan Sertcakacılar, Fatma Nihan Çağlar Turhan","doi":"10.4274/TJAR.2025.241830","DOIUrl":"10.4274/TJAR.2025.241830","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the cardiopulmonary effect during prone position (PP) on right ventricular (RV) recovery in coronavirus disease-2019 related acute respiratory distress syndrome (C-ARDS) through transesophageal echocardiography (TEE).</p><p><strong>Methods: </strong>This prospective study included 30 moderate-to-severe C-ARDS patients who were treated with PP in the first 48 h of invasive mechanical ventilation support. It was evaluated with TEE three times: before PP (T₀f), the first hour of PP (T₁), and the first hour of returning to the supine position (T₀ + 24 h) (T₂) after 23 hours of PP treatment. RV end-diastolic area/left ventricular (LV) end-diastolic area (RVEDA/LVEDA), tricuspid annular plane systolic excursion (TAPSE) and LV end-systolic eccentricity index were preferred RV evaluations as primary outcomes. Pulmonary effects of PP were evaluated as a secondary outcome, including PaO₂/FiO₂, driving pressure (dP), static compliance (Cstat), mechanical ventilation parameters, and their association with 28-day survival. Tissue DO₂ was examined as a secondary outcome, and it was calculated using the measured cardiac output through TEE.</p><p><strong>Results: </strong>With the cardiopulmonary effect of PP, the decrease in RVEDA/LVEDA, the increase in TAPSE, PaO₂/FiO₂, and Cstat, and the decrease in dP were statistically significant (<i>P</i> < 0.05). The Cstat value associated with 28-day survival showed decreased mortality for each unit increase. The Cstat cut-off value, which was statistically significant for survival, was 37.</p><p><strong>Conclusion: </strong>PP can improve RV recovery and oxygenation, but it isn't always accompanied by increased survival. An increase in the Cstat may improve survival without the development of RV dysfunction while maintaining heart-lung interaction.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":"53 2","pages":"53-61"},"PeriodicalIF":0.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative Practice Patterns of Anaesthesiologists Surrounding Glucagon-Like Peptide-1 (GLP-1) Agonist Medications.","authors":"Meghan Brennan, Sabrina H Han, Kyle Ockerman, Sonia D Mehta, Heather J Furnas, Frederik Heath, Patricia Mars, Audrey Klenke, Sarah C Sorice-Virk","doi":"10.4274/TJAR.2025.241653","DOIUrl":"10.4274/TJAR.2025.241653","url":null,"abstract":"<p><strong>Objective: </strong>Aspiration of gastric contents during induction of anaesthesia is a rare but well-recognized complication with high morbidity and mortality risk. Patients at highest risk include those with full stomachs, diabetes, hiatal hernias, gastrointestinal obstructions, severe gastroesophageal reflux, and known delayed gastric emptying. Recently, the use of glucagon-like peptide-1 (GLP-1) agonists has expanded rapidly, including their application in cosmetic weight loss. This drug class suppresses glucagon release after meals, thereby delaying gastric emptying over an undefined duration. For patients taking these medications in the perioperative period, the effect on overall aspiration risk is unknown. This survey details the current practice pattern of anaesthesiologists regarding GLP-1 agonists.</p><p><strong>Methods: </strong>An IRB-approved 30-question, uncompensated survey was distributed to 30,096 self-reported actively practicing United States members of the American Society of Anesthesiologists (ASA). The survey collected demographic information, practice information, and included questions about the management of patients taking GLP-1 agonists. To ensure participant confidentiality, no identifiable information was collected.</p><p><strong>Results: </strong>The survey response rate was 5.98%, with 1,801 surveys returned. Ninety-seven percent of respondents indicated familiarity with GLP-1 agonists, and eighty-one percent indicated they had not personally witnessed complications in patients taking GLP-1 agonists. Most respondents indicated perioperative aspiration as the largest concern and the most commonly reported witnessed complication. 62% reported having \"some\" to \"a lot\" of experience providing anaesthesia to patients taking these medications. Most respondents reported NPO guidelines consistent with current ASA practice guidelines.</p><p><strong>Conclusion: </strong>The majority of anaesthesiologists report perioperative aspiration as their highest concern for patients taking this class of medications.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":"53 2","pages":"42-52"},"PeriodicalIF":0.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endotracheal Tube Size Estimation in Paediatric Patients: A Head-to-head Comparison of Accuracy Between Ultrasonography and Age-based Formula.","authors":"Archan Jayantbhai Bhut, Kalyani Nilesh Patil, Sarita Swami","doi":"10.4274/TJAR.2025.241822","DOIUrl":"10.4274/TJAR.2025.241822","url":null,"abstract":"<p><strong>Objective: </strong>In the paediatric population, the selection of an appropriately sized endotracheal tube (ETT) is extremely important not only to ensure adequate ventilation but also to avoid post-extubation stridor and stenosis. Conventionally, formulas based on age, height, or weight are used to determine the most appropriate size. In this study, we compared ultrasonography (USG) and age-based formula for predicting the best microcuff ETT size in paediatric patients aged 1-5 years.</p><p><strong>Methods: </strong>One hundred eighteen patients, aged 1 to 5 years, with American Society of Anesthesiologists, classifications of I or II, were included. After standard general anaesthesia protocols, the subglottic diameter was assessed by USG. Intubation was performed using ETT size according to age-based formula. The best clinical fit was determined after the leak test. The internal and external diameters of the ETTs were predicted by both methods and correlated with the best-fit ETT sizes used during the procedures using Pearson's correlation. Cohen's kappa was used for statistical agreement between two methods.</p><p><strong>Results: </strong>USG had a significantly higher correlation with the best-fit model as compared to the age-based formula, with 99.2% and 77.1% agreement rates. The best-fit ETT showed a better correlation with the USG-guided estimate (r = 0.994, <i>P</i> < 0.001). The Cohen's Kappa value of 0.986 showed a statistically significantly higher agreement between USG-guided estimate and best-fit ETT.</p><p><strong>Conclusion: </strong>USG-guided estimation of subglottic diameter is a better predictor for optimally sized microcuff ETT than the age-based formula in the paediatric age group of 1-5 years. 22% of tube changes could have been prevented with ultrasound-guidance as a primary approach for estimating ETT size.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":"53 2","pages":"69-76"},"PeriodicalIF":0.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Hybrid Technique Using Video Laryngoscope-assisted Flexible Bronchoscopy to Facilitate Endotracheal Intubation in Children with Anticipated Difficult Airway: A Case Series.","authors":"K Gunasekaran, Reesha Joshi, Pradeep Karunagaran, V S G Yachendra","doi":"10.4274/TJAR.2024.241587","DOIUrl":"10.4274/TJAR.2024.241587","url":null,"abstract":"<p><p>We present a case series using a hybrid technique of video laryngoscope-assisted flexible bronchoscopy to facilitate endotracheal intubation in children with anticipated difficult airway. This series describes the management of difficult airways in four paediatric cases using the hybrid technique: two cases of Apert syndrome scheduled for cranial remodelling with orbito-facial advancement, one case of an incomplete cleft palate and retrognathia scheduled for palatoplasty, and another case of Parry Romberg syndrome scheduled for a reconstructive procedure. This case series aims to highlight the value of the hybrid technique as a safe and effective intubation modality in paediatric difficult airways.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":"53 2","pages":"77-81"},"PeriodicalIF":0.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anaesthesia Considerations on Paediatric Neurosurgery.","authors":"Rudin Domi, Filadelfo Coniglione, Asead Abdyli, Gentian Huti, Krenar Lilaj, Federico Bilotta","doi":"10.4274/TJAR.2024.241698","DOIUrl":"10.4274/TJAR.2024.241698","url":null,"abstract":"<p><p>Paediatric neurosurgery has seen significant increases and improvements because of advancements in technology and monitoring techniques. This type of surgery presents unique challenges to the anaesthesiology team because of the general characteristics of paediatric patients and the complexity of the procedures. Managing paediatric patients undergoing complex neurosurgery requires profound knowledge of age-related normal physiology and the principles of common paediatric neuroanaesthesia. This review focuses on updated information about various critical topics in paediatric neurophysiology, bleeding management, acute pain treatment, intraoperative neuromonitoring, the specifics of the sitting position, and the general principles of paediatric neuroanaesthesia.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":"53 2","pages":"34-41"},"PeriodicalIF":0.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenging Perioperative Management of a MEN2A Syndrome Patient Complicated by Eisenmenger Syndrome.","authors":"Amit Rastogi, Gaurav Agarwal, Sumit Sachan, Aditya Kapoor, Preeti Dabadghao","doi":"10.4274/TJAR.2025.241768","DOIUrl":"10.4274/TJAR.2025.241768","url":null,"abstract":"<p><p>Multiple endocrine neoplasia type 2A (MEN2A), is associated with pheochromocytoma and medullary carcinoma of the thyroid. A surgical procedure in these patients can be complicated if they have any congenital heart disease (CHD). Nowadays, CHD patients are increasingly presenting at advanced age for non-cardiac surgeries, posing unique challenges to anesthesiologists. We hereby present a 44-year-old male with Eisenmenger syndrome (ES) and MEN2A, scheduled for bilateral adrenal excision and thyroidectomy. Patients with ES require meticulous and goal-directed management during non-cardiac surgery, depending upon pulmonary hypertension, cyanosis, and right ventricular dysfunction.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":"53 2","pages":"82-86"},"PeriodicalIF":0.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation and Translation of the 3D-CAM to Turkish in Surgical Intensive Care Patients.","authors":"Sinem Sarı, Pelin Dilsiz, Tuna Eker, Samet Şahin, Meltem Derya Şahin, Bilge Doğan, Pakize Özçiftçi, Halil Özcan, Ayşenur Dostbil, Mehmet Sinan İyisoy, Oğuz Turan, Fatma Taşkın, Didar Kyenshilik, Meryem Kazaylek, İlker İnce, Alparslan Turan","doi":"10.4274/TJAR.2025.251888","DOIUrl":"10.4274/TJAR.2025.251888","url":null,"abstract":"<p><strong>Objective: </strong>Delirium is a common condition that can significantly worsen a patient's clinical status. Timely and accurate detection of this often-overlooked condition is essential for effective prevention and treatment. This study aims to validate the Turkish version of the 3-Minute Diagnostic Interview for Confusion Assessment-defined Delirium (3D-CAM-TR), which has been culturally adapted for surgical intensive care patients.</p><p><strong>Methods: </strong>This study was conducted in surgical intensive care units and wards at three academic hospitals, including 133 surgical intensive care patients. The 3D-CAM was culturally adapted and translated into Turkish. The 3D-CAM-TR was administered by trained clinicians from the first to the third postoperative day. During this period, delirium diagnosis was made by experienced psychiatrists using the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria as the reference standard. All assessors were blinded to each other's assessment results. The 3D-CAM delirium diagnosis was compared with the reference standard in all patients.</p><p><strong>Results: </strong>A total of 133 adult patients were assessed over three consecutive days, findings in 399 paired assessments. Compared to the DSM- 5-based reference standard, the sensitivity and specificity of the 3D-CAM-TR assessment were found to be 95% and 97%, respectively, for rater 1, and 93% and 99%, respectively, for rater 2, with good inter-rater reliability (Kappa coefficient=0.898, confidence interval=0.84, 0.96).</p><p><strong>Conclusion: </strong>Our resultings indicate that the 3D-CAM-TR is a dependable and precise instrument for assessing delirium in postoperative intensive care patients.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":"53 2","pages":"62-68"},"PeriodicalIF":0.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Incidence of Hemi-Diaphragmatic Paralysis Following Infraclavicular and Supraclavicular Approaches for Brachial Plexus Block: A Randomized Controlled Study.","authors":"Aruna Parameswari, Anisha Pauline Paul, Krithika U","doi":"10.4274/TJAR.2025.241648","DOIUrl":"10.4274/TJAR.2025.241648","url":null,"abstract":"<p><strong>Objective: </strong>With the regional anaesthetic technique used for brachial plexus block, the phrenic nerve (C3-C5) can be blocked due to its anatomical proximity to the brachial plexus and the effect of a significant volume of local anaesthetic deposited near the nerve roots. The goal of this study was to compare the incidence of hemi-diaphragmatic paralysis (HDP) following infraclavicular and supraclavicular approaches for brachial plexus block, using a low-volume local anaesthetic.</p><p><strong>Methods: </strong>A total of 60 patients were enrolled in this study: 30 patients were assigned to the supraclavicular brachial plexus block group, and 30 patients were assigned to the infraclavicular brachial plexus block group. Under aseptic precautions and ultrasound guidance, both groups received 20 mL of 0.5% bupivacaine. The diaphragmatic excursion was measured using ultrasound before the block and 2 hours afterward in the postoperative care unit. A reduction in excursion of more than 75% compared with pre-block values was considered complete paralysis, whereas a reduction of 25-75% was considered partial paralysis.</p><p><strong>Results: </strong>Infraclavicular brachial plexus block (3.33%) had a lower incidence of HDP compared with supraclavicular brachial plexus block (36.66%). The complications in both groups were not significant, and there was no need to use general anaesthesia.</p><p><strong>Conclusion: </strong>The incidence of phrenic nerve palsy in the supraclavicular and infraclavicular brachial plexus groups was low, with a lower incidence of HDP in the infraclavicular group.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":"53 1","pages":"20-27"},"PeriodicalIF":0.6,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}