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Karnofsky Performance Status Is Associated with Patient and Graft Survival After Liver Retransplantation 肝再移植后Karnofsky性能状态与患者和移植物存活相关。
IF 0.8 4区 医学
Transplantation proceedings Pub Date : 2026-07-01 Epub Date: 2026-06-25 DOI: 10.1016/j.transproceed.2026.06.017
Avesh J. Thuluvath, Helen Zhang, Sharmitha Yerneni, Elizabeth C. Verna
{"title":"Karnofsky Performance Status Is Associated with Patient and Graft Survival After Liver Retransplantation","authors":"Avesh J. Thuluvath,&nbsp;Helen Zhang,&nbsp;Sharmitha Yerneni,&nbsp;Elizabeth C. Verna","doi":"10.1016/j.transproceed.2026.06.017","DOIUrl":"10.1016/j.transproceed.2026.06.017","url":null,"abstract":"<div><h3>Background</h3><div>The impact of Karnofsky Performance Status (KPS), a clinical measure of functional status, on liver retransplantation (re-LT) outcomes, is unknown.</div></div><div><h3>Methods</h3><div>We performed a retrospective analysis of the United Network for Organ Sharing database of adults who underwent re-LT from January 1, 2006, to December 3, 2021, to assess the association between KPS and re-LT outcomes.</div></div><div><h3>Results</h3><div>A total of 3144 re-LT recipients were included (68% male; mean age, 52.5 ± 11.1 years). The mean Model for End-Stage Liver Disease score at re-LT was 27.5 ± 10.6, and the median time between LT and re-LT was 0.30 years. Low KPS (10%-40%) re-LT recipients had a significantly higher risk of mortality (hazard ratio [HR], 1.7; 95% confidence interval [CI], 1.3-2.2; <em>P</em> &lt; .001) and graft failure (HR, 1.5; 95% CI, 1.1-1.9; <em>P</em> = .003) compared to high KPS (80%-100%) re-LT recipients without controlling for other factors. On multivariable analysis, KPS status remained significantly associated with mortality and graft survival. Compared to the high KPS group, the low KPS group had a 1.6-fold higher risk of death (HR, 1.6; 95% CI, 1.2-2.1; <em>P</em> &lt; .01) and a 1.3-fold higher risk of graft failure (HR, 1.3; 95% CI, 1.1-1.8; <em>P</em> = .03). The association between KPS score and re-LT outcomes remained significant regardless of the time between LT and re-LT.</div></div><div><h3>Conclusion</h3><div>Our findings demonstrate that functional status is a significant predictor of re-LT outcomes and should be carefully assessed when determining re-LT candidacy.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"58 6","pages":"Pages 1143-1151"},"PeriodicalIF":0.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148321441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and Validation of a Prognostic Nomogram for Predicting 3-Month Mortality After Liver Transplantation 肝移植术后3个月死亡率预测图的建立和验证。
IF 0.8 4区 医学
Transplantation proceedings Pub Date : 2026-07-01 Epub Date: 2026-06-12 DOI: 10.1016/j.transproceed.2026.04.037
Gongming Zhang, Jing Zhang, Yifei Wang, Baihui Cui, Jing Wang, Yanan Sun, Guangming Li
{"title":"Development and Validation of a Prognostic Nomogram for Predicting 3-Month Mortality After Liver Transplantation","authors":"Gongming Zhang,&nbsp;Jing Zhang,&nbsp;Yifei Wang,&nbsp;Baihui Cui,&nbsp;Jing Wang,&nbsp;Yanan Sun,&nbsp;Guangming Li","doi":"10.1016/j.transproceed.2026.04.037","DOIUrl":"10.1016/j.transproceed.2026.04.037","url":null,"abstract":"<div><h3>Background and aims</h3><div>Identifying patients at high risk of mortality following liver transplantation and implementing timely interventions are essential to reducing fatality rates. This study aimed to develop a prognostic model to predict mortality after liver transplantation, using a nomogram based on specific risk factors.</div></div><div><h3>Methods</h3><div>The study included 1951 liver transplant recipients, divided into a training group (n = 1366) and a validation group (n=585) through stratified cluster sampling. Nine key factors were considered for the prognostic model: Child-Pugh score, MELD score, extended Intensive Care Unit stays over seven days, catheter-related bloodstream infections, delayed graft function, intraperitoneal hemorrhages, pulmonary infections, renal failure, and vascular complications. Lasso regression and Boruta feature selection were applied to identify the most important predictors. The model's effectiveness was evaluated using ROC curves, calibration plots, decision curve analysis, and internal validation.</div></div><div><h3>Results</h3><div>The model achieved an area under the curve of 0.824 in the training group and 0.774 in the validation group. Calibration plots showed good alignment with the ideal diagonal line, indicating robust predictive accuracy. Decision curve analysis demonstrated various levels of clinical benefit across a range of risk thresholds (3%-81%).</div></div><div><h3>Conclusions</h3><div>This nomogram, despite its limitations from the <u>retrospective cohort</u>, proves to be a valuable tool for predicting mortality outcomes in liver transplant recipients. It helps healthcare professionals identify high-risk patients who require urgent interventions following transplantation.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"58 6","pages":"Pages 1114-1124"},"PeriodicalIF":0.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148240882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Renal Outcomes in HBsAg-Positive Living Kidney Donors: A Retrospective Cohort Study hbsag阳性活体肾供者的肾脏预后:一项回顾性队列研究。
IF 0.8 4区 医学
Transplantation proceedings Pub Date : 2026-07-01 Epub Date: 2026-06-18 DOI: 10.1016/j.transproceed.2026.06.001
Xia Huang, Saifu Yin, Tao Lin
{"title":"Renal Outcomes in HBsAg-Positive Living Kidney Donors: A Retrospective Cohort Study","authors":"Xia Huang,&nbsp;Saifu Yin,&nbsp;Tao Lin","doi":"10.1016/j.transproceed.2026.06.001","DOIUrl":"10.1016/j.transproceed.2026.06.001","url":null,"abstract":"<div><h3>Background</h3><div>The utilization of hepatitis B surface antigen-positive (HBsAg+) living kidney donors is a strategy to expand the donor pool. However, concerns regarding their renal safety after nephrectomy persist due to the potential impact of chronic HBV infection on the solitary kidney.</div></div><div><h3>Methods</h3><div>In this retrospective cohort study, we analyzed 415 living kidney donors, including 31 (7.5%) who were HBsAg+. Donors were followed for a mean duration of 46.81 months (HBsAg+ group) and 42.10 months (HBsAg- group). The primary outcome was the change in renal function, assessed by serum creatinine levels and the incidence of an estimated glomerular filtration rate (eGFR) below 45 mL/min/1.73m². Multivariable linear regression was used to identify factors associated with post-donation renal function change.</div></div><div><h3>Results</h3><div>Baseline characteristics were comparable. At the last follow-up, there was no significant difference in serum creatinine between HBsAg+ and HBsAg- donors (81.65 µmol/L vs. 81.64 µmol/L, <em>p</em> = .996). The increase in creatinine from baseline was slightly greater in the HBsAg+ group (12.53 µmol/L vs. 11.08 µmol/L), but this difference was not statistically significant (<em>p</em> = .060). The incidence of low eGFR (&lt;45 mL/min/1.73m²) was low in both groups (3.2% vs. 0.5%, <em>p</em> = .543), with no cases of end-stage kidney disease. Multivariable analysis confirmed that HBsAg+ status was not an independent predictor of serum creatinine increase (Estimate 1.42, 95% CI: -0.16 to 3.01; <em>p</em> = .078), whereas hypertension (Estimate 1.89, <em>p</em> = .039) and diabetes (Estimate 3.28, <em>p</em> = .016) were significant predictors.</div></div><div><h3>Conclusion</h3><div>Over an intermediate-term follow-up, carefully selected HBsAg+ living kidney donors did not exhibit a significantly higher risk of renal impairment compared to HBsAg- donors. HBsAg positivity itself was not an independent risk factor for renal function decline.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"58 6","pages":"Pages 1022-1026"},"PeriodicalIF":0.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148280792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Passenger Lymphocyte Syndrome Following Minor ABO-incompatible Liver Transplantation: A Case Report 轻微abo血型不相容肝移植后乘客淋巴细胞综合征1例报告。
IF 0.8 4区 医学
Transplantation proceedings Pub Date : 2026-06-01 Epub Date: 2026-05-17 DOI: 10.1016/j.transproceed.2026.04.022
Styliani Tsoukala , Georgios C. Sotiropoulos , Nicoletta Rapti , Sevasti Ampelioti , Konstantinos Sarantos , Ioanna Stergiou , Dimitrios Xanthis , Pavlos Vernikos , Elisabeth Paramythiotou
{"title":"Passenger Lymphocyte Syndrome Following Minor ABO-incompatible Liver Transplantation: A Case Report","authors":"Styliani Tsoukala ,&nbsp;Georgios C. Sotiropoulos ,&nbsp;Nicoletta Rapti ,&nbsp;Sevasti Ampelioti ,&nbsp;Konstantinos Sarantos ,&nbsp;Ioanna Stergiou ,&nbsp;Dimitrios Xanthis ,&nbsp;Pavlos Vernikos ,&nbsp;Elisabeth Paramythiotou","doi":"10.1016/j.transproceed.2026.04.022","DOIUrl":"10.1016/j.transproceed.2026.04.022","url":null,"abstract":"<div><h3>Background</h3><div>Passenger lymphocyte syndrome (PLS) is a graft-versus-host immune complication after solid organ or hematopoietic stem cell transplantation, typically arising from minor ABO or Rh incompatibility. It is caused by the transfer of viable donor B lymphocytes that produce alloantibodies against recipient red blood cell (RBC) antigens. The syndrome presents as delayed, immune-mediated hemolysis and can be clinically significant.</div></div><div><h3>Case Presentation</h3><div>We report a 51-year-old woman (blood group B/Rh-positive) who underwent liver transplantation from a blood group O/Rh-positive donor. On postoperative day 9, she developed jaundice and a significant drop in hemoglobin, with no overt clinical signs of hemorrhage. Liver biopsy revealed moderate T-cell mediated rejection and laboratory workup confirmed immune-mediated hemolysis, consistent with PLS. Management included donor compatible red blood cell transfusion, corticosteroids, intensified immunosuppression, and monoclonal antibodies (rituximab), which resulted in stabilization and subsequent resolution of hemolysis.</div></div><div><h3>Conclusions</h3><div>Although rare, PLS should be considered in the differential diagnosis of early post-transplant anemia. Prompt recognition and appropriate transfusion strategy, with immunomodulatory therapy in severe cases, are crucial for favorable outcomes.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"58 5","pages":"Pages 903-906"},"PeriodicalIF":0.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147966108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commercial Aviation as an Alternative to Charter Flights in Liver Transplantation: A Case Report 商用航空替代包机进行肝移植:一例报告。
IF 0.8 4区 医学
Transplantation proceedings Pub Date : 2026-06-01 Epub Date: 2026-05-16 DOI: 10.1016/j.transproceed.2026.03.027
Ralph Cutler Quillin III, Achintya Kaw, Muhammad Bilal Moeen-Ud-Din, Christine E. Haugen
{"title":"Commercial Aviation as an Alternative to Charter Flights in Liver Transplantation: A Case Report","authors":"Ralph Cutler Quillin III,&nbsp;Achintya Kaw,&nbsp;Muhammad Bilal Moeen-Ud-Din,&nbsp;Christine E. Haugen","doi":"10.1016/j.transproceed.2026.03.027","DOIUrl":"10.1016/j.transproceed.2026.03.027","url":null,"abstract":"<div><div>The transition to the acuity circle liver allocation system has increased transportation distance, cold ischemia time, and procurement costs. The increase in procurement cost is largely due to a higher reliance on charter flights. Although charter flights are flexible, they are expensive and have a considerable environmental impact. At the same time, advances in controlled hypothermic preservation have extended safe preservation times and may allow broader use of ground and commercial air travel as cost-conscious alternatives to charter flights. We report a case of a donor liver preserved with contemporary hypothermic technology was transported using a commercial airline flight. A 52-year-old donor underwent donation after circulatory death with normothermic regional perfusion. The liver was preserved using the LIVERguard system and transported 356 nautical miles on a commercial flight. Total transportation costs were 14,152 dollars, compared to an estimated 19,000 dollars for a comparable charter flight with ground transfer. LIVERguard preservation time was 9 hours 30 minutes, followed by 4 hours 42 minutes of hypothermic machine perfusion, for a total cold ischemia time of 16 hours 48 minutes. The recipient was a 61-year-old female with metabolic dysfunction associated steatohepatitis and a MELD score of 21. The postoperative course was complicated only by a GI bleed. She had excellent early allograft function and was discharged home on postoperative day 15. This case suggests that commercial flights, paired with advanced hypothermic preservation, can provide a viable, cost effective, and environmentally favorable alternative to charter flights while maintaining organ quality under current allocation practices.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"58 5","pages":"Pages 925-927"},"PeriodicalIF":0.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147960554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“Construction and Evaluation of a Nomogram for Unplanned Readmission Within 1 Year After Kidney Transplantation: Based on Lasso-Logistic Regression Model” 肾移植术后1年内非计划再入院Nomogram构建与评价:基于Lasso-Logistic回归模型
IF 0.8 4区 医学
Transplantation proceedings Pub Date : 2026-06-01 Epub Date: 2026-05-23 DOI: 10.1016/j.transproceed.2026.04.016
Parth Aphale, Himanshu Shekhar, Shashank Dokania
{"title":"“Construction and Evaluation of a Nomogram for Unplanned Readmission Within 1 Year After Kidney Transplantation: Based on Lasso-Logistic Regression Model”","authors":"Parth Aphale,&nbsp;Himanshu Shekhar,&nbsp;Shashank Dokania","doi":"10.1016/j.transproceed.2026.04.016","DOIUrl":"10.1016/j.transproceed.2026.04.016","url":null,"abstract":"","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"58 5","pages":"Page 948"},"PeriodicalIF":0.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148007733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strong False-Positive Pretransplant Flow Cytometric Crossmatch Induced by Non-HLA Autoantibodies in a Nonsensitized Renal Transplant Candidate 非hla自身抗体在非致敏肾移植候选人中诱导的强假阳性移植前流式细胞术交叉配型
IF 0.8 4区 医学
Transplantation proceedings Pub Date : 2026-06-01 Epub Date: 2026-05-19 DOI: 10.1016/j.transproceed.2026.04.023
Bo Young Yoon , Ae Jung Kang , Young Soo Chung , In Hwa Jeong
{"title":"Strong False-Positive Pretransplant Flow Cytometric Crossmatch Induced by Non-HLA Autoantibodies in a Nonsensitized Renal Transplant Candidate","authors":"Bo Young Yoon ,&nbsp;Ae Jung Kang ,&nbsp;Young Soo Chung ,&nbsp;In Hwa Jeong","doi":"10.1016/j.transproceed.2026.04.023","DOIUrl":"10.1016/j.transproceed.2026.04.023","url":null,"abstract":"<div><div>Flow cytometric crossmatch (FCXM) is a sensitive method for detecting donor-specific antibodies in kidney transplantation; however, false-positive results may occur in the absence of HLA antibodies. We report a case of a 46-year-old nonsensitized male kidney transplant candidate who demonstrated persistent strong T-cell FCXM positivity despite repeatedly negative HLA antibody screening by single antigen bead assay. Complement-dependent cytotoxicity crossmatch was negative for both T and B lymphocytes. The patient had no history of prior sensitizing events, including transfusion, transplantation, or pregnancy. To exclude assay interference, serum pretreatment with EDTA, serial dilution, heat inactivation, and dithiothreitol was performed, and no clinically relevant HLA donor-specific antibodies were identified. Extended non-HLA antibody screening revealed multiple autoantibodies, including antibodies against viemtin, leucine-rich repeat transmembrane protein 2, tubulin alpha-1B chain, and CD36. These non-HLA autoantibodies were considered the most likely cause of the isolated T-cell FCXM positivity. This case highlights the diagnostic challenge posed by discordant crossmatch results and emphasizes the importance of considering non-HLA antibodies in the interpretation of FCXM. Identification of non-HLA antibody-mediated FCXM positivity may help avoid unnecessary exclusion of transplant candidates and support more informed immunologic risk assessment in pretransplant evaluation.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"58 5","pages":"Pages 886-889"},"PeriodicalIF":0.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147978004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-Anastomotic Bronchial Stenosis Leading to Dual Lobar Collapse and Ex Vacuo Pleural Effusion: A Case Report 非吻合口支气管狭窄致双叶塌陷及胸腔积液1例。
IF 0.8 4区 医学
Transplantation proceedings Pub Date : 2026-06-01 Epub Date: 2026-05-26 DOI: 10.1016/j.transproceed.2026.04.027
Sanya Chandna , Atul Mehta , Michael Machuzak , Usman Ahmad , Marc Gillinov
{"title":"Non-Anastomotic Bronchial Stenosis Leading to Dual Lobar Collapse and Ex Vacuo Pleural Effusion: A Case Report","authors":"Sanya Chandna ,&nbsp;Atul Mehta ,&nbsp;Michael Machuzak ,&nbsp;Usman Ahmad ,&nbsp;Marc Gillinov","doi":"10.1016/j.transproceed.2026.04.027","DOIUrl":"10.1016/j.transproceed.2026.04.027","url":null,"abstract":"<div><h3>Background</h3><div>Bronchial stenosis is a common airway complication following lung transplantation. Complete obstruction may result in “vanishing bronchus syndrome,” a rare occurrence that typically affects the bronchus intermedius and causes the collapse of the right middle and lower lobes. While the condition predominantly involves the right lung, it can affect any bronchopulmonary segment.</div><div>We present a case where bronchial stenosis led to the subsequent collapse of 2 independent lobes - the right upper and middle lobes. The volume loss resulted in ex vacuo pleural effusion.</div></div><div><h3>Case Report</h3><div>A 61-year-old male underwent a bilateral sequential lung transplant for rheumatoid arthritis-induced interstitial lung disease. A month later, he was hospitalized with shortness of breath. Imaging revealed bilateral pleural effusion for which he underwent decortication and pleurodesis. Follow-up surveillance bronchoscopies identified narrowing of the right upper and middle lobe bronchi, necessitating balloon dilation and lobar stent placement. During the subsequent 5-year period, the patient underwent several balloon dilations and stent replacements, which were complicated by the distal migration of the stents. This eventually led to the collapse of the right upper and middle lobes, as well as the development of ex vacuo pleural effusion.</div></div><div><h3>Conclusion</h3><div>This case demonstrates an unusual anatomic pattern of vanishing bronchus affecting 2 independent lobes despite treatment of early acute rejection. Although aggressive multimodal bronchoscopic management, including balloon dilation and stenting, failed to prevent complete lobar collapse complicated by stent migration and ex vacuo pleural effusion, the patient has achieved 87-month survival with FEV1 maintained at 79% predicted, demonstrating that acceptable long-term outcomes remain possible.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"58 5","pages":"Pages 944-947"},"PeriodicalIF":0.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148038705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Maintenance Hemodialysis Patient With Normal Perfused Renal Allograft Presenting With Hematuria and Fever: A Case Report 维持血液透析患者正常灌注同种异体肾移植出现血尿和发热1例报告。
IF 0.8 4区 医学
Transplantation proceedings Pub Date : 2026-06-01 Epub Date: 2026-05-21 DOI: 10.1016/j.transproceed.2026.03.028
Chen Shiyao , Zhou Hou'an , Wang Xiaoxing , Bi Rui , Gao Jiandong
{"title":"A Maintenance Hemodialysis Patient With Normal Perfused Renal Allograft Presenting With Hematuria and Fever: A Case Report","authors":"Chen Shiyao ,&nbsp;Zhou Hou'an ,&nbsp;Wang Xiaoxing ,&nbsp;Bi Rui ,&nbsp;Gao Jiandong","doi":"10.1016/j.transproceed.2026.03.028","DOIUrl":"10.1016/j.transproceed.2026.03.028","url":null,"abstract":"<div><h3>Background</h3><div>Hematuria and renal dysfunction after kidney transplantation often indicate acute rejection, vascular complications, or infection. Ultrasonography, being non-invasive, convenient, and radiation-free, is a primary imaging tool. Contrast-enhanced ultrasound (CEUS) is a sensitive technique for assessing microcirculatory perfusion in the renal allograft. This report describes a 43-year-old male presenting with fever and elevated creatinine six years post-transplant. Color Doppler showed no significant abnormality in the allograft, and CEUS revealed normal perfusion. However, the patient had reached end-stage renal disease (blood urea nitrogen 35.59 mmol/L, serum creatinine 1023.70 μmol/L, cystatin C 7.80 mg/L) and had been on maintenance hemodialysis for over 4 months. The 24-hour urine output at admission was minimal (∼10 mL, used for testing), showing significant hematuria and infection (red blood cells 2700.00/μL, white blood cells 1528.00/μL, urinary microalbumin 103.10 mg/L, urinary creatinine 1287.20 μmol/L). Allograft ultrasound revealed no stones, masses, or obvious lesions. This case highlights a potential dissociation between allograft perfusion status and functional outcome – specifically, normal perfusion despite severe dysfunction and failure – suggesting a unique scenario that warrants further investigation into the mechanisms of transplant kidney dysfunction.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"58 5","pages":"Pages 868-870"},"PeriodicalIF":0.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147990621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to Letter to the Editor Regarding Anti-inflammatory Effects and Pharmacokinetics of Bupivacaine in Transversus Abdominis Plane Block for Living Liver Donors Transplantation Proceedings, 57, 1095–1103 (2025) 关于布比卡因在活体肝移植中的抗炎作用和药代动力学的回复。中华医学杂志,57,1095-1103 (2025)
IF 0.8 4区 医学
Transplantation proceedings Pub Date : 2026-06-01 Epub Date: 2026-06-04 DOI: 10.1016/j.transproceed.2026.04.018
Mehmet Ridvan Yalin , Mehmet Ali Erdogan , Muharrem Ucar , Muhammed Mehdi Uremis , Yusuf Ziya Colak , Emine Ozdemir , Yilmaz Ugur , Ulku Ozgul , Selim Erdogan , Osman Kacmaz , Duygu Demiroz , Huseyin Ilksen Toprak
{"title":"Response to Letter to the Editor Regarding Anti-inflammatory Effects and Pharmacokinetics of Bupivacaine in Transversus Abdominis Plane Block for Living Liver Donors Transplantation Proceedings, 57, 1095–1103 (2025)","authors":"Mehmet Ridvan Yalin ,&nbsp;Mehmet Ali Erdogan ,&nbsp;Muharrem Ucar ,&nbsp;Muhammed Mehdi Uremis ,&nbsp;Yusuf Ziya Colak ,&nbsp;Emine Ozdemir ,&nbsp;Yilmaz Ugur ,&nbsp;Ulku Ozgul ,&nbsp;Selim Erdogan ,&nbsp;Osman Kacmaz ,&nbsp;Duygu Demiroz ,&nbsp;Huseyin Ilksen Toprak","doi":"10.1016/j.transproceed.2026.04.018","DOIUrl":"10.1016/j.transproceed.2026.04.018","url":null,"abstract":"","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"58 5","pages":"Page 951"},"PeriodicalIF":0.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148154040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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