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The Brown University Psychopharmacology Update最新文献

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Discontinuation of antipsychotics initiated in hospital improves older-adult outcomes 在医院停用抗精神病药物可改善老年人的预后
The Brown University Psychopharmacology Update Pub Date : 2025-08-04 DOI: 10.1002/pu.31351
{"title":"Discontinuation of antipsychotics initiated in hospital improves older-adult outcomes","authors":"","doi":"10.1002/pu.31351","DOIUrl":"https://doi.org/10.1002/pu.31351","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paternal exposure to valproate not linked to child neurodevelopmental disorders 父亲接触丙戊酸盐与儿童神经发育障碍无关
The Brown University Psychopharmacology Update Pub Date : 2025-08-04 DOI: 10.1002/pu.31353
{"title":"Paternal exposure to valproate not linked to child neurodevelopmental disorders","authors":"","doi":"10.1002/pu.31353","DOIUrl":"https://doi.org/10.1002/pu.31353","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oveporexton improves sleep outcomes in patients with narcolepsy overporexton改善发作性睡病患者的睡眠结果
The Brown University Psychopharmacology Update Pub Date : 2025-08-04 DOI: 10.1002/pu.31348
{"title":"Oveporexton improves sleep outcomes in patients with narcolepsy","authors":"","doi":"10.1002/pu.31348","DOIUrl":"https://doi.org/10.1002/pu.31348","url":null,"abstract":"<p>The orexin receptor 2-selective agonist oveporexton improved sleep- and wakefulness-related measures in a dose-dependent fashion relative to placebo in adults with narcolepsy type 1, a Phase 2 study has found. Most adverse events associated with oveporexton were mild to moderate, with no reports of suicidality.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clozapine-associated pneumonia Clozapine-associated肺炎
The Brown University Psychopharmacology Update Pub Date : 2025-08-04 DOI: 10.1002/pu.31346
Y. W. Francis Lam Pharm.D., FCCP
{"title":"Clozapine-associated pneumonia","authors":"Y. W. Francis Lam Pharm.D., FCCP","doi":"10.1002/pu.31346","DOIUrl":"https://doi.org/10.1002/pu.31346","url":null,"abstract":"<p>Despite clozapine's recognized efficacy for patients with treatment-resistant schizophrenia, most clinicians are aware that it can cause such serious adverse effects as agranulocytosis, seizures, myocarditis, obstipation, and orthostatic hypotension. Less well known are clinical reports and research suggesting an increased risk of pneumonia (Cepaityte et al., 2021). Other than dosage reduction, there has been little guidance on prevention of clozapine-associated pneumonia, or whether clozapine can be reinstated after its resolution.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 9","pages":"2-6"},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Your Medication Information 您的用药信息
The Brown University Psychopharmacology Update Pub Date : 2025-07-01 DOI: 10.1002/pu.31343
{"title":"Your Medication Information","authors":"","doi":"10.1002/pu.31343","DOIUrl":"https://doi.org/10.1002/pu.31343","url":null,"abstract":"<p>Memantine (generic) Namenda (brand)</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 8","pages":"9-10"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144519904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Esketamine's effects in combination with SSRI vs. SNRI show differences 艾氯胺酮联合SSRI与SNRI的效果存在差异
The Brown University Psychopharmacology Update Pub Date : 2025-07-01 DOI: 10.1002/pu.31332
{"title":"Esketamine's effects in combination with SSRI vs. SNRI show differences","authors":"","doi":"10.1002/pu.31332","DOIUrl":"https://doi.org/10.1002/pu.31332","url":null,"abstract":"<p>A retrospective cohort study has found that while esketamine is effective in combination with an antidepressant in patients with treatment-resistant depression, effects differ based on antidepressant class. Patients receiving esketamine with a serotonin-norepinephrine reuptake inhibitor (SNRI) showed improvement on more measures in comparison with the combination of esketamine and a selective serotonin reuptake inhibitor (SSRI). Study results were published online April 2, 2025, in <i>JAMA Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 8","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144520020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GLP-1s, SGLT2s associated with lower risk of Alzheimer's disease glp -1， SGLT2s与降低阿尔茨海默病风险相关
The Brown University Psychopharmacology Update Pub Date : 2025-07-01 DOI: 10.1002/pu.31339
{"title":"GLP-1s, SGLT2s associated with lower risk of Alzheimer's disease","authors":"","doi":"10.1002/pu.31339","DOIUrl":"https://doi.org/10.1002/pu.31339","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144520024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Herpes zoster vaccine has protective effect against dementia 带状疱疹疫苗对痴呆有保护作用
The Brown University Psychopharmacology Update Pub Date : 2025-07-01 DOI: 10.1002/pu.31338
{"title":"Herpes zoster vaccine has protective effect against dementia","authors":"","doi":"10.1002/pu.31338","DOIUrl":"https://doi.org/10.1002/pu.31338","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144520023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A second Phase 3 trial affirms efficacy of cytisinicline for smoking cessation 第二项3期试验证实了cytisinicline戒烟的有效性
The Brown University Psychopharmacology Update Pub Date : 2025-07-01 DOI: 10.1002/pu.31334
{"title":"A second Phase 3 trial affirms efficacy of cytisinicline for smoking cessation","authors":"","doi":"10.1002/pu.31334","DOIUrl":"https://doi.org/10.1002/pu.31334","url":null,"abstract":"<p>Smokers receiving the plant-based alkaloid cytisinicline with behavioral support showed significantly higher smoking abstinence rates compared with those receiving placebo with behavioral support, a Phase 3 replication trial has found. The incidence of adverse events was similar between the cytisinicline and placebo groups.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 8","pages":"3-4"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144520026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Review suggests need to monitor blood pressure in youths receiving ADHD medications 回顾建议需要监测接受ADHD药物治疗的青少年的血压
The Brown University Psychopharmacology Update Pub Date : 2025-07-01 DOI: 10.1002/pu.31336
{"title":"Review suggests need to monitor blood pressure in youths receiving ADHD medications","authors":"","doi":"10.1002/pu.31336","DOIUrl":"https://doi.org/10.1002/pu.31336","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144520021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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