The Brown University Psychopharmacology Update最新文献

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Review questions sustained efficacy of esketamine in treatment-resistant depression 回顾艾氯胺酮对难治性抑郁症的持续疗效
The Brown University Psychopharmacology Update Pub Date : 2025-04-29 DOI: 10.1002/pu.31310
{"title":"Review questions sustained efficacy of esketamine in treatment-resistant depression","authors":"","doi":"10.1002/pu.31310","DOIUrl":"https://doi.org/10.1002/pu.31310","url":null,"abstract":"<p>Results of a systematic review and meta-analysis suggest that esketamine has only modest efficacy in the treatment of adults with treatment-resistant depression, with initial improvement diminishing after the first few days. The results also suggest no effect of esketamine on suicidality.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 6","pages":"3"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143884135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term dopamine receptor blockade not linked to psychotic relapse 长期多巴胺受体阻断与精神病复发无关
The Brown University Psychopharmacology Update Pub Date : 2025-04-29 DOI: 10.1002/pu.31308
{"title":"Long-term dopamine receptor blockade not linked to psychotic relapse","authors":"","doi":"10.1002/pu.31308","DOIUrl":"https://doi.org/10.1002/pu.31308","url":null,"abstract":"<p>A cohort study has found that long-term use of dopamine D2 receptor antagonists was not associated with increased risk of breakthrough psychosis in patients with first-­episode schizophrenia. Risk of relapse within the cohort decreased over time, the investigators reported. Study results were published online Feb. 19, 2025, in the <i>American Journal of Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 6","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143884067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antidepressant use linked to cognitive decline in patients with dementia 抗抑郁药的使用与痴呆症患者认知能力下降有关
The Brown University Psychopharmacology Update Pub Date : 2025-04-29 DOI: 10.1002/pu.31314
{"title":"Antidepressant use linked to cognitive decline in patients with dementia","authors":"","doi":"10.1002/pu.31314","DOIUrl":"https://doi.org/10.1002/pu.31314","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 6","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143884105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Your Medication Information 您的用药信息
The Brown University Psychopharmacology Update Pub Date : 2025-04-29 DOI: 10.1002/pu.31319
{"title":"Your Medication Information","authors":"","doi":"10.1002/pu.31319","DOIUrl":"https://doi.org/10.1002/pu.31319","url":null,"abstract":"<p>Paliperidone (generic) – Invega (brand)</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 6","pages":"9-10"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143884097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study suggests benefit of continuing antipsychotic during pregnancy 研究表明怀孕期间持续服用抗精神病药物有益
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31303
{"title":"Study suggests benefit of continuing antipsychotic during pregnancy","authors":"","doi":"10.1002/pu.31303","DOIUrl":"https://doi.org/10.1002/pu.31303","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"6-8"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravenous hydroxyzine shows promise for treatment of delirium 静脉注射羟嗪有望治疗谵妄
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31305
{"title":"Intravenous hydroxyzine shows promise for treatment of delirium","authors":"","doi":"10.1002/pu.31305","DOIUrl":"https://doi.org/10.1002/pu.31305","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study finds low correspondence between known genetic variations and treatment targets 研究发现,已知基因变异与治疗目标之间的相关性较低
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31304
{"title":"Study finds low correspondence between known genetic variations and treatment targets","authors":"","doi":"10.1002/pu.31304","DOIUrl":"https://doi.org/10.1002/pu.31304","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psilocybin-assisted therapy leads to personality shifts in patients with alcohol use disorder 裸盖菇素辅助治疗导致酒精使用障碍患者的人格转变
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31300
{"title":"Psilocybin-assisted therapy leads to personality shifts in patients with alcohol use disorder","authors":"","doi":"10.1002/pu.31300","DOIUrl":"https://doi.org/10.1002/pu.31300","url":null,"abstract":"<p>Adults with alcohol use disorder who received two sessions of psilocybin-assisted therapy demonstrated personality shifts toward normalization of abnormal trait expression, a secondary analysis of a randomized trial has found. A decrease in impulsiveness was found to be associated with reduced drinking post-treatment, with the strongest effect for psilocybin-treated individuals who had engaged in moderate- or high-risk drinking before treatment.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"3-4"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive study of GLP-1 effects suggests neuropsychiatric benefits 综合研究表明GLP-1对神经精神有益处
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31301
{"title":"Comprehensive study of GLP-1 effects suggests neuropsychiatric benefits","authors":"","doi":"10.1002/pu.31301","DOIUrl":"https://doi.org/10.1002/pu.31301","url":null,"abstract":"<p>A study evaluating the effects of glucagon-like peptide-1 (GLP-1) receptor agonists on 175 health outcomes found an association with lower risk of substance use, psychotic, and neurocognitive disorders in patients diagnosed with diabetes. Conversely, use of GLP-1 drugs was associated with higher risk of gastrointestinal disorders.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"4-5"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Your Medication Information 您的用药信息
The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI: 10.1002/pu.31306
{"title":"Your Medication Information","authors":"","doi":"10.1002/pu.31306","DOIUrl":"https://doi.org/10.1002/pu.31306","url":null,"abstract":"<p>Donepezil (generic) - Aricept (brand)</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 5","pages":"9-10"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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