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The Brown University Psychopharmacology Update最新文献

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Study finds no link between prenatal acetaminophen exposure and child neurodevelopmental disorders 研究发现产前对乙酰氨基酚暴露与儿童神经发育障碍之间没有联系
The Brown University Psychopharmacology Update Pub Date : 2026-09-02 DOI: 10.1002/pu.31500
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引用次数: 0
Combining CBT with esketamine effective in reducing suicidal ideation CBT联合艾氯胺酮可有效降低自杀意念
The Brown University Psychopharmacology Update Pub Date : 2026-09-02 DOI: 10.1002/pu.31502
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引用次数: 0
Antipsychotic discontinuation in pregnancy worsens risk of relapse 妊娠期停用抗精神病药物会加重复发风险
The Brown University Psychopharmacology Update Pub Date : 2026-09-02 DOI: 10.1002/pu.31503
{"title":"Antipsychotic discontinuation in pregnancy worsens risk of relapse","authors":"","doi":"10.1002/pu.31503","DOIUrl":"https://doi.org/10.1002/pu.31503","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic drug monitoring of sertraline and clinical response 舍曲林治疗药物监测及临床反应
The Brown University Psychopharmacology Update Pub Date : 2026-09-02 DOI: 10.1002/pu.31496
Y. W. Francis Lam Pharm.D., FCCP
{"title":"Therapeutic drug monitoring of sertraline and clinical response","authors":"Y. W. Francis Lam Pharm.D., FCCP","doi":"10.1002/pu.31496","DOIUrl":"https://doi.org/10.1002/pu.31496","url":null,"abstract":"<p>Variability in drug exposure and response among individual patients can occur because of numerous factors, including age, sex, metabolic capacity, medication adherence, and the presence and magnitude of interactions with concurrently administered drugs. For decades, therapeutic drug monitoring with drug concentration determinations has been used to evaluate whether variability in drug exposure might be related to significant differences in therapeutic response to psychotropics (Hart et al., 2024; Kang &amp; Lee, 2009).</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 10","pages":"2-3"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ecopipam results in improvement in Tourette syndrome symptoms in Phase 3 trial 在3期试验中，Ecopipam改善了抽动秽语综合征的症状
The Brown University Psychopharmacology Update Pub Date : 2026-09-02 DOI: 10.1002/pu.31494
{"title":"Ecopipam results in improvement in Tourette syndrome symptoms in Phase 3 trial","authors":"","doi":"10.1002/pu.31494","DOIUrl":"https://doi.org/10.1002/pu.31494","url":null,"abstract":"<p>The novel selective dopamine D1 receptor antagonist ecopipam resulted in clinically meaningful improvement in the severity of tics in patients with Tourette syndrome, a Phase 3 trial has found. Ecopipam resulted in no significant changes in metabolic measures and no reports of movement disorders, the investigators reported. Study results were published online May 26, 2026 in <i>JAMA Neurology</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 10","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Many individuals with eating disorders are using GLP-1 medications 许多饮食失调患者正在使用GLP-1药物
The Brown University Psychopharmacology Update Pub Date : 2026-09-02 DOI: 10.1002/pu.31498
{"title":"Many individuals with eating disorders are using GLP-1 medications","authors":"","doi":"10.1002/pu.31498","DOIUrl":"https://doi.org/10.1002/pu.31498","url":null,"abstract":"<p>Individuals with eating disorders are using glucagon-like peptide-1 (GLP-1) receptor agonists at a substantially higher rate than the general population, an analysis of an ongoing cross-sectional study has concluded. The analysis found a 32.1% lifetime prevalence of GLP-1 use among adults with an eating disorder.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stimulant misuse among adults declining; high-frequency use remains a concern 成人兴奋剂滥用下降；高频使用仍然是一个问题
The Brown University Psychopharmacology Update Pub Date : 2026-09-02 DOI: 10.1002/pu.31501
{"title":"Stimulant misuse among adults declining; high-frequency use remains a concern","authors":"","doi":"10.1002/pu.31501","DOIUrl":"https://doi.org/10.1002/pu.31501","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cohort study finds post-trauma benzodiazepine use does not increase PTSD risk 队列研究发现创伤后使用苯二氮卓类药物不会增加PTSD风险
The Brown University Psychopharmacology Update Pub Date : 2026-09-02 DOI: 10.1002/pu.31497
{"title":"Cohort study finds post-trauma benzodiazepine use does not increase PTSD risk","authors":"","doi":"10.1002/pu.31497","DOIUrl":"https://doi.org/10.1002/pu.31497","url":null,"abstract":"<p>Use of benzodiazepines within 30 days of having experienced a mass traumatic event does not increase long-term risk of post-traumatic stress disorder (PTSD), a retrospective cohort study has concluded. Both earlier and later purchasers of benzodiazepines in the studied 30-day period showed lower risk of PTSD at 12 months than non-purchasers.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Initiating SSRIs in antipsychotic users carries cardiac risk 抗精神病药物使用者启动ssri类药物有心脏风险
The Brown University Psychopharmacology Update Pub Date : 2026-09-02 DOI: 10.1002/pu.31504
{"title":"Initiating SSRIs in antipsychotic users carries cardiac risk","authors":"","doi":"10.1002/pu.31504","DOIUrl":"https://doi.org/10.1002/pu.31504","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis recommends greater transparency in FDA reporting of negative trials 分析建议FDA报告负面试验时提高透明度
The Brown University Psychopharmacology Update Pub Date : 2026-09-02 DOI: 10.1002/pu.31495
{"title":"Analysis recommends greater transparency in FDA reporting of negative trials","authors":"","doi":"10.1002/pu.31495","DOIUrl":"https://doi.org/10.1002/pu.31495","url":null,"abstract":"<p>The process that led to the Food and Drug Administration's (FDA's) eventual approval of gepirone extended release (ER) for the treatment of major depressive disorder illustrates that the agency's regulatory flexibility can result in approval of drugs with questionable benefits, stated authors of a newly published special communication. The academicians suggested that the FDA should include in product labeling for approved drugs information on all of a drug's efficacy trials, including negative trials. Their report was published online June 24, 2026 in <i>JAMA Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 10","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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