{"title":"Varenicline improves abstinence from vaping in young users","authors":"","doi":"10.1002/pu.31363","DOIUrl":"https://doi.org/10.1002/pu.31363","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antimicrobial exposure and risk of depression","authors":"Y. W. Francis Lam Pharm.D., FCCP","doi":"10.1002/pu.31357","DOIUrl":"https://doi.org/10.1002/pu.31357","url":null,"abstract":"<p>Recent research findings have provided increasing evidence of a “gut-brain axis” that facilitates “communication” between the gut microbiome and the brain. For example, studies have suggested differences in gut flora composition and fecal microbiota in patients with major depressive disorder when compared with healthy controls (Cryan et al., 2019). Despite the increasing volume of data, and the well-known fact that antibiotics disrupt healthy gut flora, few studies have addressed the potential modulating effect of antibiotic exposure on mental health, including depressive illness.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review finds GLP-1s have favorable psychiatric safety profile","authors":"","doi":"10.1002/pu.31345","DOIUrl":"https://doi.org/10.1002/pu.31345","url":null,"abstract":"<p>Use of glucagon-like peptide 1 (GLP-1) receptor agonists in patients with diabetes and/or obesity did not increase risk of psychiatric adverse effects or worsening depressive symptoms, a systematic review and meta-analysis has found. Use of GLP-1s in these populations also improved several quality-of-life outcomes. Results of the review and meta-analysis were published online May 14, 2025, in <i>JAMA Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 9","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study finds no link between prenatal antidepressant exposure and childhood depression","authors":"","doi":"10.1002/pu.31347","DOIUrl":"https://doi.org/10.1002/pu.31347","url":null,"abstract":"<p>Adjusted analyses in a U.S. cohort study found that children exposed in utero to antidepressants were at no higher risk of onset of depression or anxiety than youths whose mothers did not use antidepressants or used the medications in the year before pregnancy. The results suggested that underlying maternal depression is a greater predictor of a childhood depressive diagnosis than antidepressant exposure.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Suicidality and psychotropic drugs: Another perspective","authors":"Lawrence H. Price M.D.","doi":"10.1002/pu.31350","DOIUrl":"https://doi.org/10.1002/pu.31350","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antipsychotics linked to reduced suicide risk in patients with schizophrenia","authors":"","doi":"10.1002/pu.31352","DOIUrl":"https://doi.org/10.1002/pu.31352","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to emotional stimuli weaker in SSRI users compared with psilocybin","authors":"","doi":"10.1002/pu.31349","DOIUrl":"https://doi.org/10.1002/pu.31349","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 9","pages":"6-8"},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study finds gabapentinoid treatment does not elevate risk of self-harm","authors":"","doi":"10.1002/pu.31344","DOIUrl":"https://doi.org/10.1002/pu.31344","url":null,"abstract":"<p>A population-based case series study has found that patients taking gabapentin or pregabalin did not experience an elevated risk of self-harm during treatment. Risk of self-harm was elevated during pre- and post-treatment periods, the investigators found. Study results were published online April 30, 2025 in <i>The BMJ</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 9","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}