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The Brown University Psychopharmacology Update最新文献

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Long-term study confirms safety of esketamine for treatment-resistant depression 长期研究证实艾氯胺酮治疗难治性抑郁症的安全性
The Brown University Psychopharmacology Update Pub Date : 2025-09-09 DOI: 10.1002/pu.31360
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引用次数: 0
Cohort study finds glucocorticoids increase risk of anxiety, depression 队列研究发现糖皮质激素会增加焦虑、抑郁的风险
The Brown University Psychopharmacology Update Pub Date : 2025-09-09 DOI: 10.1002/pu.31359
{"title":"Cohort study finds glucocorticoids increase risk of anxiety, depression","authors":"","doi":"10.1002/pu.31359","DOIUrl":"https://doi.org/10.1002/pu.31359","url":null,"abstract":"<p>A population-based cohort study using both self-controlled and target trial emulation approaches has reported an association between use of oral glucocorticoids and increased risk of adverse psychiatric outcomes. Use of glucocorticoids was found to be associated with higher risk of depressive, bipolar, and anxiety disorders but did not increase risk of suicidality.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Second-line strategies more effective than dose optimization in depression treatment 二线策略治疗抑郁症比剂量优化更有效
The Brown University Psychopharmacology Update Pub Date : 2025-09-09 DOI: 10.1002/pu.31358
{"title":"Second-line strategies more effective than dose optimization in depression treatment","authors":"","doi":"10.1002/pu.31358","DOIUrl":"https://doi.org/10.1002/pu.31358","url":null,"abstract":"<p>Alternative second-line treatments for major depressive disorder led to higher response and remission rates in comparison to commonly used dose optimization in a randomized trial. The combination of a selective serotonin reuptake inhibitor (SSRI) and psychotherapy resulted in the lowest prevalence of adverse events among the studied second-line strategies.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 10","pages":"3-4"},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Semaglutide shows favorable safety profile in patients receiving clozapine 西马鲁肽在接受氯氮平治疗的患者中显示出良好的安全性
The Brown University Psychopharmacology Update Pub Date : 2025-09-09 DOI: 10.1002/pu.31361
{"title":"Semaglutide shows favorable safety profile in patients receiving clozapine","authors":"","doi":"10.1002/pu.31361","DOIUrl":"https://doi.org/10.1002/pu.31361","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Augmentation with pramipexole efficacious for treatment-resistant depression 普拉克索增强治疗难治性抑郁症有效
The Brown University Psychopharmacology Update Pub Date : 2025-09-09 DOI: 10.1002/pu.31355
{"title":"Augmentation with pramipexole efficacious for treatment-resistant depression","authors":"","doi":"10.1002/pu.31355","DOIUrl":"https://doi.org/10.1002/pu.31355","url":null,"abstract":"<p>Augmenting antidepressant treatment with the dopamine D2/D3 receptor agonist pramipexole led to improvement in depressive symptoms relative to placebo at 12 weeks in patients with treatment-resistant depression, a randomized trial has found. Treatment discontinuation due to adverse events was more prevalent in the pramipexole group, investigators reported. Study results were published online June 29, 2025, in <i>Lancet Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 10","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study generally supports telehealth for ADHD medication prescribing 研究普遍支持远程医疗的ADHD药物处方
The Brown University Psychopharmacology Update Pub Date : 2025-09-09 DOI: 10.1002/pu.31364
{"title":"Study generally supports telehealth for ADHD medication prescribing","authors":"","doi":"10.1002/pu.31364","DOIUrl":"https://doi.org/10.1002/pu.31364","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fremanezumab effective for comorbid migraine and depression Fremanezumab对合并偏头痛和抑郁症有效
The Brown University Psychopharmacology Update Pub Date : 2025-09-09 DOI: 10.1002/pu.31366
{"title":"Fremanezumab effective for comorbid migraine and depression","authors":"","doi":"10.1002/pu.31366","DOIUrl":"https://doi.org/10.1002/pu.31366","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Weakened benefits of ADHD drugs over time reflect broader treated population 随着时间的推移，ADHD药物的疗效减弱反映了更广泛的治疗人群
The Brown University Psychopharmacology Update Pub Date : 2025-09-09 DOI: 10.1002/pu.31356
{"title":"Weakened benefits of ADHD drugs over time reflect broader treated population","authors":"","doi":"10.1002/pu.31356","DOIUrl":"https://doi.org/10.1002/pu.31356","url":null,"abstract":"<p>A cohort study using Swedish national data has found that while use of medication treatments for attention-deficit hyperactivity disorder (ADHD) consistently reduced risk of self-harm, unintentional injury, and other adverse outcomes, these associations weakened in later years of the study. Investigators theorized that higher prescribing rates over time incorporated more individuals with less severe symptoms. Study results were published online June 25, 2025, in <i>JAMA Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 10","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simvastatin does not improve depression in patients with comorbid obesity 辛伐他汀不能改善合并肥胖患者的抑郁
The Brown University Psychopharmacology Update Pub Date : 2025-09-09 DOI: 10.1002/pu.31362
{"title":"Simvastatin does not improve depression in patients with comorbid obesity","authors":"","doi":"10.1002/pu.31362","DOIUrl":"https://doi.org/10.1002/pu.31362","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145011997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Your Medication Information 您的用药信息
The Brown University Psychopharmacology Update Pub Date : 2025-09-09 DOI: 10.1002/pu.31367
{"title":"Your Medication Information","authors":"","doi":"10.1002/pu.31367","DOIUrl":"https://doi.org/10.1002/pu.31367","url":null,"abstract":"<p>Paroxetine immediate release (generic) Paxil (brand)</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 10","pages":"9-10"},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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