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The Brown University Psychopharmacology Update最新文献

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GLP-1s among most effective in reducing weight in antipsychotic-treated patients glp -1在抗精神病治疗患者中减肥最有效
The Brown University Psychopharmacology Update Pub Date : 2026-10-02 DOI: 10.1002/pu.31510
{"title":"GLP-1s among most effective in reducing weight in antipsychotic-treated patients","authors":"","doi":"10.1002/pu.31510","DOIUrl":"https://doi.org/10.1002/pu.31510","url":null,"abstract":"<p>A systematic review and network meta-analysis encompassing 95 studies has found considerable variation among pharmacological interventions to reduce weight in antipsychotic-treated patients with schizophrenia. The glucagon-like peptide-1 (GLP-1) receptor agonists semaglutide, liraglutide, and exenatide were among the medications found to be associated with the greatest weight reduction with the highest-certainty evidence.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 11","pages":"3-4"},"PeriodicalIF":0.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Your Medication Information 您的用药信息
The Brown University Psychopharmacology Update Pub Date : 2026-10-02 DOI: 10.1002/pu.31516
{"title":"Your Medication Information","authors":"","doi":"10.1002/pu.31516","DOIUrl":"https://doi.org/10.1002/pu.31516","url":null,"abstract":"<p>Vilazodone (generic) Viibryd (brand)</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 11","pages":"9-10"},"PeriodicalIF":0.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proof-of-concept study suggests interleukin inhibition could improve depressive symptoms 概念验证研究表明，抑制白细胞介素可以改善抑郁症状
The Brown University Psychopharmacology Update Pub Date : 2026-10-02 DOI: 10.1002/pu.31513
{"title":"Proof-of-concept study suggests interleukin inhibition could improve depressive symptoms","authors":"","doi":"10.1002/pu.31513","DOIUrl":"https://doi.org/10.1002/pu.31513","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementing pharmacogenomics for LAI antipsychotics 实施LAI抗精神病药物基因组学
The Brown University Psychopharmacology Update Pub Date : 2026-10-02 DOI: 10.1002/pu.31509
Y. W. Francis Lam Pharm.D., FCCP
{"title":"Implementing pharmacogenomics for LAI antipsychotics","authors":"Y. W. Francis Lam Pharm.D., FCCP","doi":"10.1002/pu.31509","DOIUrl":"https://doi.org/10.1002/pu.31509","url":null,"abstract":"<p>Differences among individuals in drug exposure and response are well-known variables for practicing clinicians. Over the last few decades, investigators have begun to present evidence for how pharmacogenetic strategies might optimize treatment for patients based on their genetic determinants of drug efficacy and toxicity.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 11","pages":"2-3"},"PeriodicalIF":0.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid pace of psychedelics development brings regulatory complexities 迷幻药的快速发展带来了监管的复杂性
The Brown University Psychopharmacology Update Pub Date : 2026-10-02 DOI: 10.1002/pu.31507
{"title":"Rapid pace of psychedelics development brings regulatory complexities","authors":"","doi":"10.1002/pu.31507","DOIUrl":"https://doi.org/10.1002/pu.31507","url":null,"abstract":"<p>The rapid evolution of psychedelic drug development is creating numerous regulatory challenges, from potential conditions of approval that can affect patient access to differences in federal and state policy regarding the drugs, according to authors of two newly published commentaries. One of the authors emphasized that public demand for psychedelics is far outpacing federal regulatory guidance. The articles were published online July 15, 2026 in <i>JAMA</i> <i>Psychiatry</i> and June 18, 2026 in the <i>New England Journal of Medicine</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 11","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Semaglutide improves drinking outcomes in patients with higher-severity AUD 西马鲁肽改善重度AUD患者的饮酒结局
The Brown University Psychopharmacology Update Pub Date : 2026-10-02 DOI: 10.1002/pu.31508
{"title":"Semaglutide improves drinking outcomes in patients with higher-severity AUD","authors":"","doi":"10.1002/pu.31508","DOIUrl":"https://doi.org/10.1002/pu.31508","url":null,"abstract":"<p>Individuals with moderate to severe alcohol use disorder (AUD) who received 8 weeks of treatment with the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide experienced a significant reduction in heavy-drinking days and alcohol-related consequences relative to placebo, a new Phase 2 trial has found. Semaglutide did not result in significant improvement on the primary outcome measure of alcohol craving, however. Study results were published online July 29, 2026 in the <i>American Journal of Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 11","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunopsychopharmacology: concept proven 免疫精神药理学：概念证明
The Brown University Psychopharmacology Update Pub Date : 2026-10-02 DOI: 10.1002/pu.31514
Lawrence H. Price M.D.
{"title":"Immunopsychopharmacology: concept proven","authors":"Lawrence H. Price M.D.","doi":"10.1002/pu.31514","DOIUrl":"https://doi.org/10.1002/pu.31514","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 11","pages":"7-8"},"PeriodicalIF":0.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Approvals 批准
The Brown University Psychopharmacology Update Pub Date : 2026-10-02 DOI: 10.1002/pu.31515
{"title":"Approvals","authors":"","doi":"10.1002/pu.31515","DOIUrl":"https://doi.org/10.1002/pu.31515","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Open-label extension trial of ketamine for depression shows short-term benefit 氯胺酮治疗抑郁症的开放标签扩展试验显示短期疗效
The Brown University Psychopharmacology Update Pub Date : 2026-10-02 DOI: 10.1002/pu.31512
{"title":"Open-label extension trial of ketamine for depression shows short-term benefit","authors":"","doi":"10.1002/pu.31512","DOIUrl":"https://doi.org/10.1002/pu.31512","url":null,"abstract":"","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 11","pages":"6-8"},"PeriodicalIF":0.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis finds minimal risk of childhood disorders from parental antidepressant use in pregnancy 分析发现，父母在怀孕期间使用抗抑郁药导致儿童疾病的风险最小
The Brown University Psychopharmacology Update Pub Date : 2026-10-02 DOI: 10.1002/pu.31511
{"title":"Analysis finds minimal risk of childhood disorders from parental antidepressant use in pregnancy","authors":"","doi":"10.1002/pu.31511","DOIUrl":"https://doi.org/10.1002/pu.31511","url":null,"abstract":"<p>A systematic review and meta-analysis comprising 37 studies has found that prenatal antidepressant use was associated with a modestly increased risk of attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in offspring. However, the associations observed in the analysis were attenuated or became nonsignificant after adjustment for maternal psychiatric illness and other confounding factors.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"37 11","pages":"4-5"},"PeriodicalIF":0.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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