{"title":"Esketamine's effects in combination with SSRI vs. SNRI show differences","authors":"","doi":"10.1002/pu.31332","DOIUrl":null,"url":null,"abstract":"<p>A retrospective cohort study has found that while esketamine is effective in combination with an antidepressant in patients with treatment-resistant depression, effects differ based on antidepressant class. Patients receiving esketamine with a serotonin-norepinephrine reuptake inhibitor (SNRI) showed improvement on more measures in comparison with the combination of esketamine and a selective serotonin reuptake inhibitor (SSRI). Study results were published online April 2, 2025, in <i>JAMA Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 8","pages":"1-6"},"PeriodicalIF":0.0000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Brown University Psychopharmacology Update","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pu.31332","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A retrospective cohort study has found that while esketamine is effective in combination with an antidepressant in patients with treatment-resistant depression, effects differ based on antidepressant class. Patients receiving esketamine with a serotonin-norepinephrine reuptake inhibitor (SNRI) showed improvement on more measures in comparison with the combination of esketamine and a selective serotonin reuptake inhibitor (SSRI). Study results were published online April 2, 2025, in JAMA Psychiatry.
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