{"title":"艾氯胺酮联合SSRI与SNRI的效果存在差异","authors":"","doi":"10.1002/pu.31332","DOIUrl":null,"url":null,"abstract":"<p>A retrospective cohort study has found that while esketamine is effective in combination with an antidepressant in patients with treatment-resistant depression, effects differ based on antidepressant class. Patients receiving esketamine with a serotonin-norepinephrine reuptake inhibitor (SNRI) showed improvement on more measures in comparison with the combination of esketamine and a selective serotonin reuptake inhibitor (SSRI). Study results were published online April 2, 2025, in <i>JAMA Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 8","pages":"1-6"},"PeriodicalIF":0.0000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Esketamine's effects in combination with SSRI vs. SNRI show differences\",\"authors\":\"\",\"doi\":\"10.1002/pu.31332\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>A retrospective cohort study has found that while esketamine is effective in combination with an antidepressant in patients with treatment-resistant depression, effects differ based on antidepressant class. Patients receiving esketamine with a serotonin-norepinephrine reuptake inhibitor (SNRI) showed improvement on more measures in comparison with the combination of esketamine and a selective serotonin reuptake inhibitor (SSRI). Study results were published online April 2, 2025, in <i>JAMA Psychiatry</i>.</p>\",\"PeriodicalId\":22275,\"journal\":{\"name\":\"The Brown University Psychopharmacology Update\",\"volume\":\"36 8\",\"pages\":\"1-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Brown University Psychopharmacology Update\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/pu.31332\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Brown University Psychopharmacology Update","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pu.31332","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Esketamine's effects in combination with SSRI vs. SNRI show differences
A retrospective cohort study has found that while esketamine is effective in combination with an antidepressant in patients with treatment-resistant depression, effects differ based on antidepressant class. Patients receiving esketamine with a serotonin-norepinephrine reuptake inhibitor (SNRI) showed improvement on more measures in comparison with the combination of esketamine and a selective serotonin reuptake inhibitor (SSRI). Study results were published online April 2, 2025, in JAMA Psychiatry.
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