Josephine-L K Murray, Virginia Hernandez-Santiago, Frank Sullivan, Joanna Hornal, Farhana Badshah, Ben Keatley, Jillian Galbraith, Pam Channer, Anne Fearfull, Anne Haddow, Eleanor Johnston, Maureen Ward, Veronica O'Carroll
{"title":"Interprofessional collaborative practice in health and social care for people living with multimorbidity: a scoping review protocol.","authors":"Josephine-L K Murray, Virginia Hernandez-Santiago, Frank Sullivan, Joanna Hornal, Farhana Badshah, Ben Keatley, Jillian Galbraith, Pam Channer, Anne Fearfull, Anne Haddow, Eleanor Johnston, Maureen Ward, Veronica O'Carroll","doi":"10.1186/s13643-024-02730-x","DOIUrl":"10.1186/s13643-024-02730-x","url":null,"abstract":"<p><strong>Background: </strong>Multimorbidity, the co-existence of two or more conditions within an individual at any one time, is globally increasing and forecasted to rise. This poses a significant challenge for current models of healthcare delivery, which are now ill-equipped to meet the future population health needs. Interprofessional collaborative practice is a specific way professionals work closely together and with patients and their families to improve patient outcomes. Evidence suggests it can improve outcomes for people living with a single condition. What remains unknown is if interprofessional collaborative practice has been used to improve the outcomes of people living with multimorbidity, and if so, to what extent?</p><p><strong>Methods: </strong>A scoping review is proposed to identify prior peer-reviewed research and grey literature related to interprofessional collaborative practice for multimorbidity in health and social care settings. A search strategy will identify primary, peer-reviewed research and grey literature. An initial limited search will be conducted to identify relevant existing systematic reviews. Their methods will be examined and their search terms scrutinised. A second comprehensive search will be used to interrogate four databases, looking back 10 years, seeking articles published in English, French, Spanish or Portuguese. Hand searching will be performed on all included full-text articles for any articles missing from the two steps above. Critical data will be extracted by adapting existing data abstraction forms based on the needs of the research objectives. These forms will be piloted before use. The results will be analysed descriptively. If appropriate, qualitative content analysis may be undertaken. Where sufficient numbers of homogeneous interventions exist, meta-analysis techniques will be applied. Results will be presented in tabular, graphic, and diagrammatic information displays.</p><p><strong>Discussion: </strong>This scoping review will provide an overview of the current evidence base of interprofessional collaborative practice used internationally for people living with multimorbidity in health and social care settings. These findings will provide valuable information to improve health and social care practice as well as change systems and policy to meet the population need of multimorbidity.</p><p><strong>Systematic review registration: </strong>The protocol was submitted to Open Science Framework on 19 December 2023 and registered on OSF Registries. Registration DOI: https://doi.org/10.17605/OSF.IO/UXHG3 .</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"14 1","pages":"3"},"PeriodicalIF":6.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Katharina Böhm-Hustede, Johanna Sophie Lubasch, Anna Thalea Hoogestraat, Eike Buhr, Antje Wulff
{"title":"Barriers and facilitators to the implementation and adoption of computerised clinical decision support systems: an umbrella review protocol.","authors":"Anna Katharina Böhm-Hustede, Johanna Sophie Lubasch, Anna Thalea Hoogestraat, Eike Buhr, Antje Wulff","doi":"10.1186/s13643-024-02745-4","DOIUrl":"10.1186/s13643-024-02745-4","url":null,"abstract":"<p><strong>Background: </strong>The implementation of computerised clinical decision support systems has the potential to enhance healthcare by improving patient safety, practitioner performance, and patient outcomes. Notwithstanding the numerous advantages, the uptake of clinical decision support systems remains constrained, thereby impeding the full realisation of their potential. To ensure the effective and successful implementation of these systems, it is essential to identify and analyse the reasons for their low uptake and adoption. This protocol outlines an umbrella review, which will synthesise the findings of existing literature reviews to generate a comprehensive overview of the barriers and facilitators to the implementation and adoption of decision support systems across healthcare settings.</p><p><strong>Methods: </strong>This umbrella review protocol was developed in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) guidelines. Searches for eligible articles will be conducted in four electronic bibliographic databases, including PubMed/MEDLINE, IEEE Xplore, Scopus, and Web of Science. Obtained results will be independently screened by four reviewers based on pre-defined eligibility criteria. The risk of bias will be assessed for all eligible articles. Data on barriers and facilitators to the implementation and adoption of clinical decision support systems will be extracted, summarised, and further categorised into themes that aim to describe the originating environment or concept of the respective factor. The frequency of all identified barriers and facilitators within the group of included reviews will be determined in order to establish a prioritisation of the factors.</p><p><strong>Discussion: </strong>This umbrella review protocol presents a methodology for the systematic synthesis of barriers and facilitators to the implementation and adoption of clinical decision support systems across healthcare settings. The umbrella review will enable the development of novel implementation and adoption strategies that reinforce the identified facilitators and circumvent barriers, thereby promoting the use-oriented evaluation and effective utilisation of clinical decision support systems.</p><p><strong>Systematic review registration: </strong>PROSPERO CRD42024507614.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"14 1","pages":"2"},"PeriodicalIF":6.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An updated network meta-analysis of non-pharmacological interventions for primary hypertension in adults: insights from recent studies.","authors":"Ziwen Chen, Qifu Li, Tao Xu, Xueli Zhou, Yunjie Shu, Taipin Guo, Fanrong Liang","doi":"10.1186/s13643-024-02744-5","DOIUrl":"10.1186/s13643-024-02744-5","url":null,"abstract":"<p><strong>Background: </strong>Primary hypertension significantly impacts global cardiovascular health, contributing to increased mortality rates and posing a substantial public health challenge. Recognizing the growing evidence supporting non-pharmacological interventions (NPIs) for controlling primary hypertension, our study employs Network Meta-Analysis (NMA) to comprehensively assess their efficacy.</p><p><strong>Methods: </strong>This review updates a prior systematic review by searching for original literature on NPIs for primary hypertension from 2013 to 2024. We conducted a thorough search in eight databases, including PubMed, Embase, Web of Science, Cochrane Central Register of Controlled Trials, Allied and Complementary Medicine Database, CNKI, WanFang Data, and Chongqing VIP, identifying potential randomized controlled trials (RCTs) from January 1, 2013, to August 1, 2024. Primary outcomes included the mean changes in blood pressure before and after treatment. Analysis was performed using GeMTC package (R 4.2.3), and Stata 17.0. The confidence of evidence was examined using Confidence in Network Meta-Analysis (CINeMA).</p><p><strong>Results: </strong>Utilizing NMA, we reviewed 9,189 studies, identifying 54 eligible articles with 5,827 participants. Investigating 22 distinct NPIs, the focus was on changes in systolic and diastolic blood pressure pre and post-treatment. Lifestyle intervention + Tai Chi significantly reduced systolic (-21.75 mm Hg; 95% CI -33.25 to -10.02) and diastolic blood pressure (-13.62 mm Hg; 95% CI -23.14 to -3.71) compared to usual care and other NPIs. Consistency and regression analyses did not reveal significant differences.</p><p><strong>Conclusion: </strong>This review provides a comprehensive evaluation of NPIs for primary hypertension, emphasizing lifestyle + Tai Chi as a preferred NPI. Breathing exercises show potential in lowering systolic blood pressure, and acupuncture + tui na demonstrates effectiveness in reducing diastolic blood pressure, outperforming other interventions. The study reinforces the role of NPIs in managing primary hypertension, providing a foundation for future hypertension research.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"318"},"PeriodicalIF":6.3,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11686877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Gould, Haoze Cui, Norine Ma, George Chalkiadis, Andrew Davidson, Kerr Graham, Erich Rutz
{"title":"Tranexamic acid in hip and spine surgery for children with cerebral palsy - a PRISMA-compliant scoping review.","authors":"Daniel Gould, Haoze Cui, Norine Ma, George Chalkiadis, Andrew Davidson, Kerr Graham, Erich Rutz","doi":"10.1186/s13643-024-02734-7","DOIUrl":"10.1186/s13643-024-02734-7","url":null,"abstract":"<p><p>Many children with cerebral palsy (CP) are frail and require major hip and/or spine surgeries associated with substantial blood loss. Tranexamic acid (TXA) is commonly used to reduce blood loss, but there is uncertainty around the optimal dose and timing of administration. There have been reviews in sub-populations and specific dosing regimens, but a broad overview of the available literature is lacking. The aim of this review was to map available evidence on TXA in hip and spine surgery for children with CP. Given the heterogeneous literature, a prospectively registered scoping review was conducted. Eligibility criteria were broad. Three screeners were involved, with the senior author consulted when disagreements were not resolved through discussion.Titles and abstracts of 14,609 records were screened, with 52 records included. Two additional records were obtained from grey literature and citation searching. Cohort studies (50.0%) were the most common. Most records (76.9%) were on spine surgery. TXA dose varied widely. Loading doses range from 5 to 100 mg/kg and intraoperative infusions from 1 to 10 mg/kg/h. Dose was not reported in 35.2% of records. Primary outcome measures included blood loss and transfusion requirements. TXA was generally reported to be safe. None of the included records reported postoperative TXA administration.While TXA is generally considered safe, there was mixed evidence on efficacy. Much of the evidence was drawn from studies in which TXA was used in patients at higher risk of bleeding or with reduced physiological reserve. There was no evidence for TXA being used postoperatively, when a large proportion of transfusions occur.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"315"},"PeriodicalIF":6.3,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11673357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic accuracy of metagenomic next-generation sequencing in pulmonary tuberculosis: a systematic review and meta-analysis.","authors":"Yajie You, Ying Meng Ni, Guochao Shi","doi":"10.1186/s13643-024-02733-8","DOIUrl":"10.1186/s13643-024-02733-8","url":null,"abstract":"<p><strong>Background: </strong>Metagenomic next-generation sequencing (mNGS) has emerged as a promising tool in clinical practice due to its unbiased approach to pathogen detection. Its diagnostic performance in pulmonary tuberculosis (PTB), however, remains to be fully evaluated.</p><p><strong>Objective: </strong>This study aims to systematically review and Meta-analyze the diagnostic accuracy of mNGS in patients with PTB.</p><p><strong>Methods: </strong>We conducted a literature search in PubMed (MEDLINE), Web of Science, Cochrane, and EMBASE databases, including studies published up to 2024. Studies comparing the diagnostic accuracy of mNGS with other methods such as Xpert-MTB/RIF and Mycobacteria tuberculosis (MTB) culture using bronchoalveolar lavage fluid (BALF), sputum, and lung biopsy tissue were included. Preclinical studies, review articles, editorials, conference abstracts, and book chapters were excluded. Statistical analysis was performed using Rev-man5, R package metabias, and Stata software.</p><p><strong>Results: </strong>Thirteen studies met the inclusion criteria and were included in the meta-analysis. The pooled sensitivity and specificity of mNGS for PTB were 83% (95% CI: 69-91%) and 99% (95% CI: 92-100%), respectively. Subgroup analyses revealed that in BALF, mNGS demonstrated a pooled sensitivity of 73% (95% CI: 61-82%) and specificity of 98% (95% CI: 92-100%); in the sputum, the pooled sensitivity was 60% (95% CI: 38-87%) with a specificity of 99% (95% CI: 96-100%); and in the lung biopsy tissue, the pooled sensitivity was 71% (95% CI: 38-95%) and the specificity was 98% (95% CI: 93-100%). For Xpert-MTB/RIF, the pooled sensitivity and specificity were 72% (95% CI: 53-85%) and 100% (95%CI: 100-100%), respectively. Subgroup analyses demonstrated that in BALF, Xpert-MTB/RIF exhibited a pooled sensitivity of 69% (95% CI: 53-81%) and a specificity of 100% (95% CI: 77-100%). The pooled sensitivity and specificity of mycobacteria culture were 50% (95% CI: 36-64%) and 100% (95% CI: 83-100%), respectively. Subgroup analyses indicated that in BALF, the pooled sensitivity of mycobacteria culture was 44% (95% CI: 37-52%) with a specificity of 100% (95% CI: 8-100%); in the sputum, the pooled sensitivity was 42% (95% CI: 21-65%) and the specificity was 100% (95% CI: 100-100%). When combining mNGS with Xpert-MTB/RIF, the pooled sensitivity and specificity were 79% (95% CI: 40-97%) and 98% (95% CI: 95-100%), respectively.</p><p><strong>Conclusion: </strong>mNGS demonstrates similar diagnostic accuracy to Xpert-MTB/RIF in PTB and outperforms mycobacteria culture in terms of sensitivity. Furthermore, mNGS exhibits good detection capabilities across various PTB clinical samples.</p><p><strong>Systematic review registration: </strong>PROSPERO CRD42023427586.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"317"},"PeriodicalIF":6.3,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11674177/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hybrid Service Delivery for voluntary, community and social enterprise organisations working with adults with learning disabilities and/or autism: a realist review protocol.","authors":"Danielle Varley, Kris Southby, Joanne Trigwell, Sally Sj Brown, Nicola Lines, Amy Hearn, Anne-Marie Bagnall","doi":"10.1186/s13643-024-02732-9","DOIUrl":"10.1186/s13643-024-02732-9","url":null,"abstract":"<p><strong>Background: </strong>Delivery of health and care services using a combination of remote and/or in-person channels and digital and/or traditional tools (Hybrid Service Delivery, HSD) is increasingly seen as a way of improving quality and affordability, improving access, personalisation and sustainability, and reducing inequalities. Across the voluntary, community and social enterprise sector (VCSE), using a combination of remote and/or in-person channels and digital and/or traditional tools (HSD) has enabled the essential provision of services for people who have learning disabilities and/or autistic (LDA). However, it is unclear how different tools and channels have been used, what worked well or not well, for whom, and in what circumstances. The aim of this realist review is to explore how VCSE organisations can effectively use digital technologies alongside or instead of in-person activity to provide social care services to adults with learning disabilities and/or autism. This review protocol is presented in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocol (PRISMA-P).</p><p><strong>Methods: </strong>We will conduct a participatory realist review. Following realist review methodology, and involving people with LDA and organisations who deliver services to them, we will define the scope of the review/theory development, search for and appraise evidence, extract and synthesise findings, and develop the narrative. Using a developed strategy, electronic databases (Academic Search Complete, CINAHL, MEDLINE, PsycInfo, SCOPUS, Social Science Citation Index and Social Policy and Practice) will be searched. A data extraction table will be used to assist in sifting, sorting and organising relevant information from identified studies. For each proposition statement, relevant data from the identified literature will be synthesised and compared with the proposed theory to develop an understanding of how, why and when hybrid delivery works in different settings with different populations.</p><p><strong>Discussion: </strong>This review aims to collate and synthesise evidence relating to hybrid service delivery in VCSE organisations to provide social care services to LDA adults. By conducting a participatory realist review, we anticipate that the findings will lead to a greater understanding of contextual factors and therefore more relevant recommendations.</p><p><strong>Systematic review registration: </strong>PROSPERO CRD42024457161.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"316"},"PeriodicalIF":6.3,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11673684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rui Yang, Cheng Hu, Yuxin Zhuo, Wen Wang, Qingyuan Tan, Yuxin Shen, Kun Jiang, Xin Sun, Qing Xia, Lihui Deng
{"title":"Efficacy and safety of Chinese tonic medicines for treating sepsis or septic shock: a protocol for a systematic review and Bayesian network meta-analysis of randomized controlled trials.","authors":"Rui Yang, Cheng Hu, Yuxin Zhuo, Wen Wang, Qingyuan Tan, Yuxin Shen, Kun Jiang, Xin Sun, Qing Xia, Lihui Deng","doi":"10.1186/s13643-024-02736-5","DOIUrl":"10.1186/s13643-024-02736-5","url":null,"abstract":"<p><strong>Background: </strong>Sepsis is a life-threatening organ dysfunction with high morbidity and mortality. Various studies have demonstrated the effectiveness of Chinese tonic medicines (CTMs) in treating sepsis or septic shock. However, trials directly comparing the efficacy and safety of different CTMs for sepsis or septic shock are still lacking. To identify the most optimal CTM for treating sepsis or septic shock, we plan to perform a systematic review and network meta-analysis of various CTMs used for sepsis or septic shock patients.</p><p><strong>Methods: </strong>Randomized controlled trials (RCTs) that investigated the efficacy and safety of CTMs for patients with sepsis or septic shock will be systematically searched in Pubmed, Embase, Cochrane Central Register of Controlled Trials, Scopus, Web Of Science, CBM, CNKI, Wanfang, and VIP databases from inception to November 2023. The quality of the included studies will be assessed using the Cochrane Risk of Bias V.2.0. tool. The confidence of evidence will be evaluated through the CINeMA (Confidence in Network Meta-Analysis) web application. Primary outcomes include the delta Sequential Organ Failure Assessment (△SOFA) score at day 7 after interventions and 28-day mortality. Secondary outcomes comprise delta serum lactate levels (△Lac) and delta mean arterial pressure (△MAP) at day 7 after interventions as well as total dose and duration of vasoactive drugs. Safety outcome includes adverse drug reactions or adverse drug events (ADRs/ADEs). The Bayesian network meta-analysis will be conducted using the \"BUGSnet\" package in R version 4.2.2. The surface under the cumulative ranking curve (SUCRA) values will be used to rank each treatment. Statistical inconsistency assessment, publication bias assessment, heterogeneity analysis, sensitivity analysis, and subgroup analysis will be performed.</p><p><strong>Discussion: </strong>This study will provide new insights into the efficacy and safety of various CTMs used in sepsis or septic shock patients, providing help for future clinical practice and research.</p><p><strong>Systematic review registration: </strong>CRD42023482572.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"314"},"PeriodicalIF":6.3,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11670501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anita Andreano, Vito Lepore, Pietro Magnoni, Alberto Milanese, Caterina Fanizza, Deborah Testa, Alessandro Musa, Adele Zanfino, Paola Rebora, Lucia Bisceglia, Antonio Giampiero Russo
{"title":"Diagnostic accuracy of case-identification algorithms for heart failure in the general population using routinely collected health data: a systematic review.","authors":"Anita Andreano, Vito Lepore, Pietro Magnoni, Alberto Milanese, Caterina Fanizza, Deborah Testa, Alessandro Musa, Adele Zanfino, Paola Rebora, Lucia Bisceglia, Antonio Giampiero Russo","doi":"10.1186/s13643-024-02717-8","DOIUrl":"10.1186/s13643-024-02717-8","url":null,"abstract":"<p><strong>Background: </strong>Heart failure (HF), affecting 1-4% of adults in industrialized countries, is a major public health priority. Several algorithms based on administrative health data (HAD) have been developed to detect patients with HF in a timely and inexpensive manner, in order to perform real-world studies at the population level. However, their reported diagnostic accuracy is highly variable.</p><p><strong>Objective: </strong>To assess the diagnostic accuracy of validated HAD-based algorithms for detecting HF, compared to clinical diagnosis, and to investigate causes of heterogeneity.</p><p><strong>Methods: </strong>We included all diagnostic accuracy studies that utilized HAD for the diagnosis of congestive HF in the general adult population, using clinical examination or chart review as the reference standard. A systematic search of MEDLINE (1946-2023) and Embase (1947-2023) was conducted, without restrictions. The QUADAS-2 tool was employed to assess the risk of bias and concerns regarding applicability. Due to low-quality issues of the primary studies, associated with both the index test and the reference standard definition and conduct, and to the high level of clinical heterogeneity, a quantitative synthesis was not performed. Measures of diagnostic accuracy of the included algorithms were summarized narratively and presented graphically, by population subgroups.</p><p><strong>Results: </strong>We included 24 studies (161,524 patients) and extracted 36 algorithms. Algorithm selection was based on type of administrative data and DOR. Six studies (103,018 patients, 14 algorithms) were performed in the general outpatient population, with sensitivities ranging from 24.8 to 97.3% and specificities ranging from 35.6 to 99.5%. Eight studies (14,957 patients, 10 algorithms) included hospitalized patients with sensitivities ranging from 29.0 to 96.0% and specificities ranging from 65.8 to 99.2%. The remaining studies included subgroups of the general population or hospitalized patients with cardiologic conditions and were analyzed separately. Fourteen studies had one or more domains at high risk of bias, and there were concerns regarding applicability in 9 studies.</p><p><strong>Discussion: </strong>The considerable percentage of studies with a high risk of bias, together with the high clinical heterogeneity among different studies, did not allow to generate a pooled estimate of diagnostic accuracy for HAD-based algorithms to be used in an unselected general adult population.</p><p><strong>Systematic review registration: </strong>PROSPERO CRD42023487565.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"313"},"PeriodicalIF":6.3,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11668106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A study on the workplace cultural violence against nurses: a systematic review and meta-analysis.","authors":"Masoumeh Shohani, Hamed Tavan","doi":"10.1186/s13643-024-02721-y","DOIUrl":"10.1186/s13643-024-02721-y","url":null,"abstract":"<p><strong>Introduction: </strong>Cultural violence includes any offensive behavior regarding ethnicity, race, language, religion, and place of birth devaluing human dignity. The purpose of this study was to investigate workplace cultural violence against nurses by systematic review and meta-analysis.</p><p><strong>Materials and methods: </strong>The guideline of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was followed. The search was independently conducted in ISI, Cochrane Library, Google Scholar, PubMed, and Scopus by two researchers. We used mesh keywords to recruit publications from different regions of the world between 2002 and 2017. Data was analyzed using meta-analysis and STATA software. To determine the heterogeneity, Q and I<sup>2</sup> indices were used.</p><p><strong>Results: </strong>A total of 50 articles were found from which 8 were ultimately included in the systematic review process. The overall rate of workplace cultural violence among nurses was 17.25% (95% CI 16.83-17.66, I<sup>2</sup> = 99.7%, P = 0.0001). Also, the rate of workplace cultural violence against nurses and patients' relatives and companions was 8.21% (95% CI 7.61-8.81, I<sup>2</sup> = 99.7%, P = 0.0001). The meta-regression of cultural violence in terms of sample size and year of study rendered a significant decrease in the violence rate by increasing years and sample size (P < 0.001).</p><p><strong>Conclusion: </strong>Although not all cases of cultural violence are reported and recorded, the rate of cultural violence against nurses is decreasing according to the results of our study. Nevertheless, by providing good services and appropriate education to patients, the overall incidence of cultural violence is expected to be further reduced.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"311"},"PeriodicalIF":6.3,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}