Swiss medical weekly最新文献

{"title":"Hereditary alpha-tryptasemia - a potential cause of severe anaphylactic reactions and a modifier of mast cell diseases.","authors":"Axel Rüfer, Gerhard Müllner, Oliver Fuchs, Wolfgang R Sperr, Gregor Hoermann","doi":"10.57187/s.3679","DOIUrl":"https://doi.org/10.57187/s.3679","url":null,"abstract":"<p><p>Hereditary alpha-tryptasemia (HAT) is an autosomal dominant genetic trait affecting 4% to 6% of the general population. Hereditary alpha-tryptasemia is caused by an excess of alpha tryptase encoding TPSAB1 copy numbers on one parenteral allele, most often duplications or triplications, leading to elevated levels of basal serum tryptase. There might be a gene dosage effect between the number of additional TPSAB1 copies, the level of basal serum tryptase and the severity of clinical symptoms, including atopic, cutaneous, gastrointestinal, musculoskeletal, autonomic and neuropsychiatric manifestations. Hereditary alpha-tryptasemia is a potential risk factor for severe anaphylactic reactions. The prevalence of hereditary alpha-tryptasemia is higher in patients with systemic mastocytosis. In the diagnostic workup of patients with anaphylactic reactions and symptoms of mast cell mediator release after measurement of basal serum tryptase, it is therefore essential to screen for both the KIT D816V activating point mutation and hereditary alpha-tryptasemia by droplet digital polymerase chain reaction. Such a diagnostic approach can identify patients with hereditary alpha-tryptasemia, which may allow the avoidance of further diagnostic workup with bone marrow examination. Moreover, it can identify patients at high risk of anaphylactic reactions. So far, no targeted therapy for hereditary alpha-tryptasemia is available. Treatment for symptom control consists of H1- and H2-blockers, leukotriene antagonists and cromoglicic acid. Urticaria and anaphylaxis are especially successfully treated with the monoclonal anti-IgE-antibody omalizumab in patients with hereditary alpha-tryptasemia. H1-blockers and steroids are sufficient in emergencies. As hereditary alpha-tryptasemia is a hereditary condition, first-degree relatives with anaphylactic reactions or symptoms of mast cell mediator release should be tested for hereditary alpha-tryptasemia after measurement of basal serum tryptase.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"3679"},"PeriodicalIF":2.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reporting of paediatric exercise-induced respiratory symptoms by physicians and parents: an observational prospective study.","authors":"Eva S L Pedersen, Sarah Glick, Carmen C M De Jong, Cristina Ardura-Garcia, Anja Jochmann, Carmen Casaulta, Katharina Hartog, Diana Marangu-Boore, Dominik Mueller-Suter, Nicolas Regamey, Florian Singer, Alexander Moeller, Claudia E Kuehni","doi":"10.57187/s.3939","DOIUrl":"https://doi.org/10.57187/s.3939","url":null,"abstract":"<p><strong>Study aims: </strong>Routinely collected health data are increasingly used for research; however important anamnestic details may be missing from medical records. We compared physician documentation of paediatric exercise-induced respiratory symptoms in clinical notes with parental questionnaire responses for the same children.</p><p><strong>Methods: </strong>We analysed data from the Swiss Paediatric Airway Cohort (SPAC), a multicentre observational study of children treated in Swiss outpatient pulmonology clinics. We included children aged 6 to 17 years who were referred to a paediatric pulmonologist for evaluation of exercise-induced respiratory symptoms. Features of exercise-induced respiratory symptoms recorded by physicians were extracted from outpatient clinic letters transmitted to the referring physician, while parent-reported exercise-induced respiratory symptom data was collected from a standardised questionnaire completed at Swiss Paediatric Airway Cohort enrolment. We calculated agreement between physician-documented and parent-reported exercise-induced respiratory symptom characteristics using Cohen's and Fleiss's kappa.</p><p><strong>Results: </strong>Of 1669 children participating in the Swiss Paediatric Airway Cohort (2017-2019), 193 (12%) met the inclusion criteria, of whom 48% were girls. Physicians provided detailed information on exercise-induced respiratory symptoms in 186 (96%) outpatient clinic letters. Documented characteristics included: type of physical activity triggering exercise-induced respiratory symptoms (69%), location of exercise-induced respiratory symptoms in chest or throat (48%), respiratory phase of exercise-induced respiratory symptoms (45%) and timing of exercise-induced respiratory symptoms during or after exercise (37%). Previous bronchodilator use (94%) and its effect on exercise-induced respiratory symptoms (88%) were consistently documented by physicians. The clinic letters for children diagnosed with dysfunctional breathing more often contained detailed exercise-induced respiratory symptom characteristics than those diagnosed with asthma. The level of agreement between physician-documented and parent-reported exercise-induced respiratory symptoms was moderate for use of bronchodilators (κ = 0.53) and poor-to-fair for all other features (κ = 0.01-0.36).</p><p><strong>Conclusion: </strong>This study highlights that outpatient clinic letters may lack some details on exercise-induced respiratory symptom characteristics - information that parents could provide. A standardised and detailed method for documenting paediatric respiratory symptoms in the coordinated data infrastructure may enhance future analyses of routinely collected health data.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"3939"},"PeriodicalIF":2.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conference report: Trends, new technologies and implications for dementia diagnostics, treatment and care in Switzerland.","authors":"Julius Popp, Reto W Kressig, Mélanie Bieler-Aeschlimann, Miriam Rabl, Marcello Ienca, Andreas U Monsch, Hans Pihan, Stefan Klöppel, Tatjana Meyer-Heim, Stefanie Becker","doi":"10.57187/s.4017","DOIUrl":"10.57187/s.4017","url":null,"abstract":"<p><p>Dementia diseases represent a major burden for the directly affected people, their relatives and modern society. Despite considerable efforts in recent years, early and accurate disease diagnosis and monitoring is still a challenge while no cure is available in most cases. New drugs, in particular disease-modifying therapies, and recent technological advancements offer promising perspectives. The integration of novel biomarkers, artificial intelligence and digital health tools has the potential to transform dementia care, making it more personalised, efficient and adapted to the living conditions and needs of older people. In November 2023, the 7th Dementia Summit convened a panel of experts from geriatrics, neurology, neuropsychology, psychiatry, ethics as well as general medicine to discuss interdisciplinary challenges, advancements and their implications for the future of dementia care in Switzerland. The conference underscored the importance of a multidisciplinary approach to successfully integrate new technologies in both clinical-translational research and dementia prevention, diagnosis and care. While recent innovations represent major steps forward, their implementation also comes with important challenges including questions on healthcare system preparedness and adaptation, ethical aspects, technology literacy, acceptance and appropriate use.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4017"},"PeriodicalIF":2.1,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between surgeon case load and revision rates in total hip arthroplasty: Evidence from the Swiss National Joint Registry.","authors":"Andreas Ladurner, Karlmeinrad Giesinger, Bernhard Jost, Vilijam Zdravkovic","doi":"10.57187/s.3850","DOIUrl":"10.57187/s.3850","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Study aims: &lt;/strong&gt;Higher surgeon volume has been correlated with improved therapy outcomes following total hip arthroplasty, and many countries have implemented minimum volume standards as a precondition for claiming reimbursement. However, there are large differences between healthcare systems worldwide and the applicability of international studies to a particular local healthcare environment may be limited. The aim of this study was to assess the relationship between surgeon case load (= number of procedures per year) and short-term revision rates (within two years of the index procedure) in patients undergoing primary total hip arthroplasty for hip osteoarthritis in a nationwide, registry-based study. In addition, the effects of increasing minimum volume standard thresholds on the potential reduction of the revision burden was simulated.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;All patients registered in the Swiss National Joint Registry (SIRIS) for undergoing primary total hip arthroplasty for hip osteoarthritis between 2015 and 2021 were considered. Patients were aggregated according to the lead surgeon's individual code. Surgeons lacking five years of uninterrupted practice were excluded. Multiple logistic and bivariate multinomial regressions were employed to model the odds of revision surgery (overall and for specific diagnoses) as a function of surgeon case load. Two-year revision rates, the proportional reduction of the revision burden and the number of patients hypothetically needing treatment reassignment to higher-volume surgeons were simulated for increasing minimum volume standard thresholds.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;In total, 74,565 total hip arthroplasty procedures performed by 384 surgeons were assessed. The mean surgeon case load was 28.7 total hip arthroplasties / year (min/max: 1.8/269.1; median: 18.1). The average overall 2-year revision rate in the observation period was 2.25%. A higher surgeon case load was associated with lower cumulative revision rates (revision for any reason, and revision due to infection, dislocation and femoral periprosthetic fracture). Overall revision rates of surgeons with a minimal case load of up to 10 / 20 / 50 total hip arthroplasties / year were 2.18% / 2.01 % / 1.70%, respectively. Implementation of a minimum volume standard of 10 / 20 / 50 total hip arthroplasties / year would reduce the overall 2-year revision rates by 3.2%, 10.5% and 23.8%, respectively, but also require that 5.1%, 18.1% and 53.8% of patients be reassigned to higher-volume surgeons instead of initially intended lower volume surgeons.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;A higher surgeon case load independently predicts a lower overall 2-year revision rate in patients undergoing primary total hip arthroplasty for hip osteoarthritis in Switzerland. Implementation of a minimal case load has the potential to significantly reduce 2-year revision rates, at the cost of more patients needing to have their treatment rea","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"3850"},"PeriodicalIF":2.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Equitable health care in the context of migration.","authors":"Anne Jachmann, Julia Brandenberger, Matthis Schick","doi":"10.57187/s.4245","DOIUrl":"10.57187/s.4245","url":null,"abstract":"<p><p>The health policy guiding principle of equitable access to healthcare faces barriers in the context of migration, on the part of both those affected and the health system. The operationalised measurement of health inequity, the training and sensitisation of healthcare professionals regarding needs-based care, diversity, transcultural and socio-medical aspects, and ensuring high-quality communication are among the measures that can contribute to reducing inequitable care (e.g. underuse) in this population.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4245"},"PeriodicalIF":2.1,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A call for universal access to science: how the Swiss Medical Weekly aims to contribute.","authors":"Stefan Weiler, Natalie Marty, Jan Roth, Gérard Waeber","doi":"10.57187/s.4543","DOIUrl":"10.57187/s.4543","url":null,"abstract":"<p><p>No abstract available.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4543"},"PeriodicalIF":2.1,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health of informal caregivers during the COVID-19 pandemic: a Swiss cohort study.","authors":"Cédric Follonier, Nick Pullen, Hélène Baysson, María-Eugenia Zaballa, Francesco Pennacchio, Stephanie Schrempft, Sara Levati, Mayssam Nehme, Idris Guessous, Silvia Stringhini, Elsa Lorthe","doi":"10.57187/s.3884","DOIUrl":"10.57187/s.3884","url":null,"abstract":"<p><strong>Aims of the study: </strong>The COVID-19 pandemic and related public health measures have disrupted healthcare systems and may have impacted informal caregivers' mental health due to increased responsibilities and limited access to support services. This study aimed to examine the prevalence of mental distress among caregivers and non-caregivers and identify risk and protective factors for mental distress in caregivers during the COVID-19 pandemic.</p><p><strong>Methods: </strong>Data were collected from participants in Specchio-COVID19, a population-based cohort in Geneva, Switzerland. Mental distress was measured using the 12-item General Health Questionnaire (GHQ-12) in June 2021. The prevalence of distress was compared between caregivers and non-caregivers. Risk and protective factors for mental distress among caregivers were explored using logistic regressions.</p><p><strong>Results: </strong>Among the 5416 participants, 1086 (20%) reported helping someone in a non-professional manner with activities of daily life and were considered caregivers. Mental distress was more frequent in caregivers than in non-caregivers (41% vs 37%, p = 0.010). In caregivers, limited social support (adjusted odds ratio [aOR] = 1.25 [95% confidence interval: 1.10, 1.42]), caring for an individual with a mental condition (aOR = 1.21 [1.05, 1.41]), living over 10 km away from the care recipient (aOR = 1.17 [1.02, 1.34]), feeling more isolated in one's caregiving role (aOR = 1.20 [1.08, 1.32]), worrying about caregiving ability in case of COVID-19 or quarantine (aOR = 1.18 [1.08, 1.28]) and experiencing reduced availability of healthcare professionals (aOR = 1.11 [1.02, 1.22]) were associated with increased odds of mental distress.</p><p><strong>Conclusion: </strong>Informal caregivers experienced higher levels of mental distress than non-caregivers during the COVID-19 pandemic. This study highlights the need for public health policies that enhance both formal and informal support networks and include rapidly implementable solutions for caregiving continuity, benefiting both caregivers and their care recipients.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"3884"},"PeriodicalIF":2.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Swiss Stroke Society position paper on atrial fibrillation monitoring and management after ischaemic stroke: a shift from understanding the index stroke to preventing the next one.","authors":"Thomas Meinel, Markus Arnold, Laurent Roten, Philipp Krisai, Marie-Luise Mono, Catherine Gebhard, Leo Bonati, Timo Kahles, Urs Fischer, Marcel Arnold, Mira Katan","doi":"10.57187/s.4170","DOIUrl":"10.57187/s.4170","url":null,"abstract":"<p><p>This position paper on the detection of atrial fibrillation after ischaemic stroke is a statement of the \"Heart and Brain\" committee of the Swiss Stroke Society. This position paper summarises present knowledge on the detection of atrial fibrillation after ischaemic stroke or transient ischaemic attack. An interdisciplinary standard for monitoring on the stroke unit and after discharge is proposed respecting recent developments and Swiss particularities. The main evolution in the field is that the role of atrial fibrillation screening after stroke or transient ischaemic attack has shifted from understanding the index stroke to preventing the next stroke; it therefore should also be performed in patients with certain other stroke aetiologies, e.g. symptomatic carotid artery stenosis. The duration of atrial fibrillation monitoring should be based on an individualised risk assessment incorporating clinical characteristics as well as cardiac and laboratory biomarkers. Given the paucity of randomised controlled data on this topic, this position paper intends to give practical advice to healthcare professionals involved in stroke care in Switzerland based on a consensus between experts in the field.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4170"},"PeriodicalIF":2.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of the United Kingdom's and Switzerland's healthcare financing systems for achieving equity and efficiency goals.","authors":"Ata Mohajer-Bastami, Sarah Moin, Benedict Sweetman, Ahmed R Ahmed, Marion Head, Edgar Gelber, Suhaib J S Ahmad, Aristomenis K Exadaktylos","doi":"10.57187/s.4101","DOIUrl":"10.57187/s.4101","url":null,"abstract":"<p><p>Healthcare financing systems in the United Kingdom and Switzerland were compared with a focus on efficiency and equity. The United Kingdom's National Health Service employs the Beveridge model. It is predominantly funded through taxation and aims to provide free healthcare at the point of use. Switzerland's healthcare financing system is based on the Bismarck model. This social health insurance model is structured around compulsory health plans for all residents.</p><p><strong>Methods: </strong> Healthcare financing systems were compared using World Health Organization reports, national health statistics and peer-reviewed literature. Efficiency was evaluated using metrics including cost-effectiveness ratios and healthcare outcomes. Equity was assessed by examining disparities in access to healthcare and socioeconomic health outcomes.</p><p><strong>Results: </strong> The National Health Service excels at administrative efficiency and providing equitable access to care. It faces challenges such as geographical disparities in service availability and perceptions of underfunding. Switzerland spends comparatively more on healthcare but delivers superior health outcomes. Issues arise with providing equitable care to all citizens, particularly affecting low-income and undocumented populations.</p><p><strong>Conclusion: </strong>The National Health Service is a leader in providing equitable healthcare but must address falling health outcomes while working within financial constraints. Switzerland demonstrates excellent healthcare outcomes and patient satisfaction but requires measures to ensure equitable service delivery. Ongoing policy adjustments are necessary to balance equity and efficiency while meeting meet new healthcare demands.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4101"},"PeriodicalIF":2.1,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age at diagnosis of paediatric unilateral and bilateral permanent hearing loss in Eastern Switzerland: a retrospective cohort study.","authors":"Samuel P Hofmann, Sandro J Stoeckli, Jochen Rosenfeld","doi":"10.57187/s.4014","DOIUrl":"10.57187/s.4014","url":null,"abstract":"<p><strong>Study aim: </strong>Undiagnosed and therefore untreated permanent paediatric hearing loss can have a detrimental impact on a child's speech, language, social and educational development, and quality of life. Therefore, early diagnosis is required for successful treatment with hearing aids to minimise the negative impact of hearing loss. Newborn hearing screening programmes may have decreased the average age at diagnosis of hearing loss worldwide, but outcomes vary widely between countries. In this study, we therefore aimed to assess the median age of children at diagnosis of permanent unilateral and bilateral hearing loss in Eastern Switzerland.</p><p><strong>Methods: </strong>In this retrospective cohort study, children born in Eastern Switzerland with permanent hearing loss diagnosed at the Division of Paediatric Audiology at the Cantonal Hospital of St Gallen (the tertiary referral centre for Eastern Switzerland) were included. The study period was from 1 January 2014 to 31 December 2019. The primary endpoint was age at diagnosis of permanent unilateral or bilateral hearing loss. Descriptive data collected were the type and WHO grade of hearing loss, the status of newborn hearing screening and other information such as path of referral and place of residence.</p><p><strong>Results: </strong>In total, 107 children with permanent hearing loss were included in this study. Overall, the median age at diagnosis was 45.0 months (interquartile range [IQR] 5.7-74.8). The median age at diagnosis for children with bilateral hearing loss was 25.8 months (IQR 3.6-70.5), compared to 63.1 months (IQR 11.4-88.5) for children with unilateral hearing loss. For children with bilateral hearing loss, the median age at diagnosis was lower with higher WHO grades of hearing loss: 65.6 months (IQR 11.1-131.6) for grade I vs 4.5 months (IQR 2.2-6.0) for grade IV. Children with bilateral hearing loss and a documented failed newborn hearing screen were diagnosed early: median age at diagnosis 4.0 months (IQR 2.2-12.3).</p><p><strong>Conclusion: </strong>In conclusion, the age at diagnosis of paediatric permanent hearing loss in our study is variable and, in some cases, late. This applies particularly to bilateral hearing loss that should have been diagnosed by the newborn hearing screen in congenital cases and unilateral hearing loss.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4014"},"PeriodicalIF":2.1,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}