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Determinants and health-related consequences of screen time in children and adolescents: post-COVID-19 insights from a prospective cohort study. 儿童和青少年屏幕时间的决定因素和健康相关后果:来自一项前瞻性队列研究的covid -19后见解
IF 2.1 4区 医学
Swiss medical weekly Pub Date : 2025-06-16 DOI: 10.57187/s.4247
Viviane Richard, Elsa Lorthe, Roxane Dumont, Andrea Loizeau, Hélène Baysson, María-Eugenia Zaballa, Julien Lamour, Mayssam Nehme, Rémy P Barbe, Klara M Posfay-Barbe, Idris Guessous, Silvia Stringhini
{"title":"Determinants and health-related consequences of screen time in children and adolescents: post-COVID-19 insights from a prospective cohort study.","authors":"Viviane Richard, Elsa Lorthe, Roxane Dumont, Andrea Loizeau, Hélène Baysson, María-Eugenia Zaballa, Julien Lamour, Mayssam Nehme, Rémy P Barbe, Klara M Posfay-Barbe, Idris Guessous, Silvia Stringhini","doi":"10.57187/s.4247","DOIUrl":"10.57187/s.4247","url":null,"abstract":"<p><strong>Aims: </strong>This study aims to provide age-specific prevalence of time spent on-screen among children and adolescents, to identify its sociodemographic and family-related determinants and to assess its impact on physical and psychosocial health outcomes.</p><p><strong>Methods: </strong>Data was drawn from the SEROCoV-KIDS prospective cohort study, which includes randomly selected children living in Geneva, Switzerland. Daily screen time, sociodemographic and family characteristics were collected at baseline (December 2021 to June 2022). Physical and psychosocial health outcomes were measured at one-year follow-up.</p><p><strong>Results: </strong>Among 674 children (2-8 years old), 752 preadolescents (9-13 years old) and 434 adolescents (14-17 years old), median daily screen time was 0h29, 1h14 and 3h18, respectively. Lower parental education and poorer parenting practices were associated with higher screen time in all age groups. In children only, poor parental mental health (+14 minutes/day; 95% CI: 2-27) and work-family conflicts (+6 minutes/day; 95% CI: 2-10) were related to increased screen time. After adjustment, elevated screen time was associated with an increased likelihood of poor physical-, emotional- and school-related quality of life in preadolescents and adolescents and of social difficulties in adolescents one year later.</p><p><strong>Conclusion: </strong>Almost all children engage with screens, but those from socially disadvantaged backgrounds and with strained families face a heightened risk of prolonged screen time. The health consequences we identified call for close monitoring.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4247"},"PeriodicalIF":2.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Registry-based surveillance of paediatric home respiratory support in Switzerland: methodology and initial findings. 瑞士儿科家庭呼吸支持的基于登记的监测:方法和初步发现。
IF 2.1 4区 医学
Swiss medical weekly Pub Date : 2025-06-05 DOI: 10.57187/s.4193
Sophie Guerin, Christian Bieli, Regula Corbelli, Thomas Ferry, Miriam Giaranna, Matthias Horn, Silvia Miano, Nicolas Regamey, Daniel Trachsel, Sylvain Blanchon
{"title":"Registry-based surveillance of paediatric home respiratory support in Switzerland: methodology and initial findings.","authors":"Sophie Guerin, Christian Bieli, Regula Corbelli, Thomas Ferry, Miriam Giaranna, Matthias Horn, Silvia Miano, Nicolas Regamey, Daniel Trachsel, Sylvain Blanchon","doi":"10.57187/s.4193","DOIUrl":"10.57187/s.4193","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;The use of long-term home respiratory support in children has increased dramatically worldwide in recent decades. However, no national data are available in Switzerland since the last survey in 2001. In 2022, the national prospective Swiss Paediatric Home Respiratory Support (SwissPedHRS) registry was created on behalf of the Swiss Society of Paediatric Pulmonology, involving all centres caring for children with home respiratory support. Its main goal is to prospectively describe and study the population of children requiring home respiratory support in Switzerland. This first publication aims to present the SwissPedHRS methodology and describe the current paediatric population with home respiratory support in Switzerland and its evolution from 2001 to 2023.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Inclusion criteria in the registry are age &lt;18 years, use of home respiratory support for ≥3 months and follow-up in Switzerland. The seven paediatric centres caring for patients with long-term home respiratory support in Switzerland participated, asking all their patients who met the criteria to participate. Each centre designated a local person to enter data collected from medical files into a dedicated database. Inclusions began in April 2022. Data from all patients included during the first year of the registry (i.e. until March 2023) were extracted, and the following data were analysed: sex; age at inclusion; underlying pathology; age, place, and context of home respiratory support initiation; decisive test leading to home respiratory support initiation; breathing disorder mechanism; and type of home respiratory support.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The registry included 146 patients, and the prevalence of children with home respiratory support in Switzerland was estimated at 11.9/100,000 children (59% boys, 41% girls). The most common underlying medical conditions were related to neuro-muscular (38%) and central nervous system (25%) diseases. The home respiratory support type was bilevel positive airway pressure (BPAP) for 67% of patients, continuous positive airway pressure (CPAP) for 32%, and high flow nasal cannula for 1%. Respiratory support was delivered invasively (via tracheostomy) for 14%. The median age at home respiratory support initiation was 6.6 years. Home respiratory support was initiated electively in 68% of patients and in acute situations (weaning failure after an acute respiratory exacerbation, neonatal hospitalisation, or surgery) in 32%. The place of initiation was either an outpatient clinic (19%), standard care unit (15%) or intensive/intermediate care unit (66%).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;SwissPedHRS is the first national prospective registry dedicated to children with home respiratory support. It is a valuable resource for improving knowledge and, therefore, the management of children with home respiratory support. Analysis of the first year's data in the SwissPedHRS registry showed a ","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4193"},"PeriodicalIF":2.1,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk prediction for major postoperative complications in people with chronic spinal cord injury/disorder and stage III and IV pressure injury. 慢性脊髓损伤/障碍及III期和IV期压力损伤患者术后主要并发症的风险预测
IF 2.1 4区 医学
Swiss medical weekly Pub Date : 2025-06-05 DOI: 10.57187/s.3977
Carina Fähndrich, Armin Gemperli, Michael Baumberger, Michael Harder, Dirk J Schaefer, Reto Wettstein, Anke Scheel-Sailer
{"title":"Risk prediction for major postoperative complications in people with chronic spinal cord injury/disorder and stage III and IV pressure injury.","authors":"Carina Fähndrich, Armin Gemperli, Michael Baumberger, Michael Harder, Dirk J Schaefer, Reto Wettstein, Anke Scheel-Sailer","doi":"10.57187/s.3977","DOIUrl":"10.57187/s.3977","url":null,"abstract":"<p><strong>Background: </strong>Approximately 20% of flap surgeries in people with spinal cord injury/disorder and stage III and IV pressure injury result in a major complication requiring re-surgery. Although several factors are associated with postoperative complications according to the literature, there is no risk prediction model for major postoperative complications in the treatment of stage III and IV pressure injuries in people with spinal cord injury/disorder.</p><p><strong>Study aim: </strong>The study aims to predict the risk of major postoperative complications in people with spinal cord injury/disorder and stage III and IV pressure injury at hospital admission.</p><p><strong>Setting: </strong>The study was conducted in a Swiss acute and rehabilitation hospital for people with spinal cord injury/disorder that specialises in the treatment of people with spinal cord injury/disorder using the Basel Decubitus Approach.</p><p><strong>Methods: </strong>We performed a retrospective cohort study based on routinely collected clinical data in a Swiss hospital. Risk predictors for major postoperative complications during hospitalisation in pressure injuries over the sacrum/coccyx, ischium or trochanter between 01/2016 and 12/2022 were identified using a mixed effects logistic Bayesian LASSO analysis.</p><p><strong>Results: </strong>We included 252 treatment procedures in 167 individuals. Major complications occurred in 48 (19%) treatment procedures. Estimated glomerular filtration rate (eGFR) according to the cystatin formula (odds ratio [OR] 0.91, confidence interval [CI] 0.62-1.02), vitamin D (25-hydroxy vitamin D; OR 1.05, CI 0.98-1.23), vitamin B12 (OR 0.91, CI 0.74-1.05), sodium (OR 0.75, CI 0.16-1.05) and C-reactive protein (CRP; OR 0.98, CI 0.79-1.07) were found to be predictive of major complications at hospital admission.</p><p><strong>Conclusion: </strong>For the Basel Decubitus Approach, high levels of eGFR, vitamin B12 and sodium negatively affected major postoperative complications and should, therefore, be assessed during hospital stay. Further investigation is needed to determine the positive effect of high vitamin D and low CRP levels on major postoperative complications.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"3977"},"PeriodicalIF":2.1,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bleeding risk after native and transplant kidney biopsy - a single-centre observational study. 原生和移植肾活检后出血风险-单中心观察性研究。
IF 2.1 4区 医学
Swiss medical weekly Pub Date : 2025-06-05 DOI: 10.57187/s.4409
Céline Fontana, Matthias Diebold, Patrizia Amico, Patricia Hirt-Minkowski, Caroline Wehmeier, Helmut Hopfer, Thomas Menter, Stefan Schaub, Juerg Steiger, Michael Dickenmann
{"title":"Bleeding risk after native and transplant kidney biopsy - a single-centre observational study.","authors":"Céline Fontana, Matthias Diebold, Patrizia Amico, Patricia Hirt-Minkowski, Caroline Wehmeier, Helmut Hopfer, Thomas Menter, Stefan Schaub, Juerg Steiger, Michael Dickenmann","doi":"10.57187/s.4409","DOIUrl":"10.57187/s.4409","url":null,"abstract":"<p><strong>Study aim: </strong>Renal biopsies provide important and decisive information for diagnosis and therapy. Although biopsies are considered safe, bleeding complications remain a concern. We analysed the complication rate after kidney biopsies in native and transplant kidneys and their association with platelet function analyser bleeding time (PFA BT) and estimated glomerular filtration rate (eGFR).</p><p><strong>Methods: </strong>This single-centre observational study included all patients who underwent an ultrasound-guided kidney biopsy at the University Hospital Basel from 2015 to August 2019. The main objective was to investigate the association of PFA BT with significant bleeding complications in kidney biopsies. Significant bleeding was defined as a haemoglobin decrease of >10 g/l within 48 hours or the need for transfusion after bleeding, according to the discretion of the treating physician. The pre-biopsy assessment included bleeding time using PFA BT, INR, thrombocyte count, and eGFR.</p><p><strong>Results: </strong>A total of 819 kidney biopsies-285 native and 534 transplant-were analysed. Complications occurred in 32 biopsies (3.9%): 18 (6.3%) in native and 14 (2.6%) in transplant kidneys. Bleeding was the most frequent complication in both groups. Overall, low eGFR (p = 0.01) and prolonged PFA BT (p = 0.02) were associated with bleeding complications. In native kidney biopsies, inpatient biopsy was associated with bleeding complications (p = 0.005), while in transplant kidney biopsies, bleeding complications were associated with time after transplantation (p <0.001), prolonged PFA BT (p <0.001), and diagnostic biopsies (p = 0.01). In the multivariable model, low eGFR was the only significant factor associated with bleeding complications (odds ratio 3.57, 95% confidence interval 1.76-7.23, p <0.001).</p><p><strong>Conclusions: </strong>A low eGFR, especially below 30 ml/min, is associated with increased bleeding risk in native and transplant kidney biopsies.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4409"},"PeriodicalIF":2.1,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Supervisors' self-assessment of feedback skills: a psychometric validation study of the English version of the SwissSETQ questionnaire for supervisors. 主管对反馈技能的自我评价:英语版SwissSETQ主管问卷的心理测量验证研究。
IF 2.1 4区 医学
Swiss medical weekly Pub Date : 2025-05-30 DOI: 10.57187/s.4178
Fabienne Schwitz, Joy Backhaus, Monika Brodmann Maeder, Eva K Hennel
{"title":"Supervisors' self-assessment of feedback skills: a psychometric validation study of the English version of the SwissSETQ questionnaire for supervisors.","authors":"Fabienne Schwitz, Joy Backhaus, Monika Brodmann Maeder, Eva K Hennel","doi":"10.57187/s.4178","DOIUrl":"10.57187/s.4178","url":null,"abstract":"<p><strong>Study aims: </strong>We created an instrument to assess the supervisors' perspective on their feedback behaviour to residents and investigated its validity. Our instrument is based on the SETQsmart, a Dutch instrument for assessing the quality of supervision in clinical training and the SwissSETQ, its German adaptation for residents. Our instrument is in English to ensure relevance across all Swiss language regions. The study specifically sought: to replicate the factor structure of the original trainee questionnaire for supervisors; to verify the alignment of SwissSETQ and SETQsmart domains with the factor structure; and to evaluate the psychometric properties of the English version.</p><p><strong>Methods: </strong>The original SwissSETQ was translated into English, maintaining the Swiss context and local language usage. The questionnaire was adjusted to reflect the supervisor's perspective. The translated questionnaire was then distributed among supervisors in all Swiss cardiology training sites, and data were collected using the SoSci Survey platform between March and April 2024. The statistical analysis, including exploratory factor analysis (EFA) with promax rotation, Bartlett's test of sphericity, Kaiser-Meyer-Olkin (KMO) coefficient and psychometric evaluation, was conducted using R software.</p><p><strong>Results: </strong>Of approximately 600 cardiology supervisors in Switzerland, 207 responded, with 135 valid cases remaining after data cleaning. The factor analysis identified three factors: Teaching structure, Attitude of the supervisor and Role modelling, resulting in a shortened 23-item questionnaire. The Kaiser-Meyer-Olkin coefficient was 0.83, and Bartlett's test was significant, confirming data suitability for factor analysis. The factors demonstrated high internal consistency, with Cronbach's α values of 0.89, 0.77 and 0.87, respectively. The partial credit model indicated the need for a revised 5-point Likert scale for better response distribution. No significant differences were found between factors and sociodemographic variables, suggesting the English version's applicability across all Swiss language regions.</p><p><strong>Conclusions: </strong>The study investigated the English-translated and supervisor-adapted version of the SwissSETQ, demonstrating good psychometric properties and a clear factor structure. The instrument is suitable for use across different Swiss language regions, enhancing its utility in a multilingual context. The findings support the potential of the SwissSETQ to facilitate cross-cultural and cross-linguistic collaboration in medical training. Future research should explore additional factors influencing teaching quality, such as work environment and supervisor motivation.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4178"},"PeriodicalIF":2.1,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Active hepatitis B virus vaccination in the prevention of viral reactivation in liver transplantation recipients with previous hepatitis B infection: a cohort study. 乙肝病毒活动性疫苗接种在预防乙肝感染肝移植受者病毒再激活中的作用:一项队列研究
IF 2.1 4区 医学
Swiss medical weekly Pub Date : 2025-05-30 DOI: 10.57187/s.4116
Eric Adler, Yasemin Krucker, Mirjam Kolev, Nasser Semmo
{"title":"Active hepatitis B virus vaccination in the prevention of viral reactivation in liver transplantation recipients with previous hepatitis B infection: a cohort study.","authors":"Eric Adler, Yasemin Krucker, Mirjam Kolev, Nasser Semmo","doi":"10.57187/s.4116","DOIUrl":"10.57187/s.4116","url":null,"abstract":"<p><strong>Background and aim of the study: </strong>For many years, the standard treatment following liver transplantation for hepatitis B has been a combination of hepatitis B immunoglobulin and nucleos(t)ide analogues such as entecavir and tenofovir. However, because of the high costs and logistical challenges of long-term hepatitis B immunoglobulin use, alternative approaches such as vaccination and hepatitis B immunoglobulin-free regimens are being explored. This study gathered information on a potential response (or lack thereof) and addressed the adverse events associated with active immunisation in liver transplant recipients in a Swiss cohort with hepatitis B virus (HBV)-related diseases after discontinuing hepatitis B immunoglobulin.</p><p><strong>Methods: </strong>Participants were recruited at the University Hospital of Bern between January 2022 and December 2023. Eligibility was restricted to liver transplant recipients with HBV-related disease who were receiving hepatitis B immunoglobulin and nucleos(t)ide analogue therapy at the time of study entry. The primary outcome was HBV relapse following hepatitis B immunoglobulin discontinuation; secondary outcomes included the response rate to active immunisation and reported adverse events. After exclusion, 18 patients were analysed. These patients, under ongoing immunosuppression and antiviral nucleos(t)ide analogue therapy, received active immunisation a minimum of 4 weeks after stopping hepatitis B immunoglobulin. Blood samples were collected at baseline and 4 weeks after vaccination, with follow-up extending for at least 12 months. Responders were defined as those with anti-HB levels of >10 IU/l. All patients received at least three vaccinations.</p><p><strong>Results: </strong>Six patients responded to the active immunisation with anti-HBs development, showing a response rate of 33.3%. No side effects or HBV recurrence were reported during the study period.</p><p><strong>Conclusion: </strong>In this cohort, following liver transplantation for hepatitis B, patients who discontinued hepatitis B immunoglobulin while continuing nucleos(t)ide analogue therapy showed no relapse of hepatitis B, and a double-dose vaccination regimen yielded a modest response rate. These findings warrant further investigation into optimising vaccination strategies in this population.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4116"},"PeriodicalIF":2.1,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex distribution in tuberculosis disease in children, adolescents, and adults in a low-incidence country: a retrospective population-based cohort study. 低发病率国家儿童、青少年和成人结核病的性别分布:一项基于人群的回顾性队列研究
IF 1.9 4区 医学
Swiss medical weekly Pub Date : 2025-05-29 DOI: 10.57187/s.4187
Daniela Neudecker, Ekkehardt Altpeter, Nicole Ritz, Nora Fritschi
{"title":"Sex distribution in tuberculosis disease in children, adolescents, and adults in a low-incidence country: a retrospective population-based cohort study.","authors":"Daniela Neudecker, Ekkehardt Altpeter, Nicole Ritz, Nora Fritschi","doi":"10.57187/s.4187","DOIUrl":"https://doi.org/10.57187/s.4187","url":null,"abstract":"<p><strong>Aim: </strong>Globally, tuberculosis incidence shows notable sex disparity, with higher rates observed in males. While this pattern is well documented in adults from high-incidence countries, the influence of sex on tuberculosis incidence in children and adolescents, particularly in low-incidence settings, remains unclear. This study investigated sex-specific tuberculosis incidence rates across all age groups, focusing on adolescents, in a low-incidence country.</p><p><strong>Methods: </strong> In this retrospective cohort study, data from the Swiss Federal Office of Public Health (FOPH) tuberculosis database, which centrally consolidates mandatory notifications from physicians and laboratories across Switzerland, were analysed from 2000 to 2021. Tuberculosis incidence rates and male-to-female ratios were calculated and stratified by sex and age. Adolescence was divided into early (10-14 years) and late (15-19 years) stages for detailed analysis.</p><p><strong>Results: </strong>Over 22 years, the average tuberculosis incidence in Switzerland was 6.78 per 100,000 population, with an overall male-to-female ratio of 1:0.75 (p <0.001). Among the 11,872 notified cases, 832 occurred in adolescents, yielding an incidence rate of 4.39 per 100,000. In late adolescence, males had a significantly higher tuberculosis incidence rate (5.73 per 100,000) than females (2.97 per 100,000, p <0.001), resulting in a male-to-female ratio of 1:0.5. Additionally, data on asylum seekers revealed nearly twice as many males as females arriving in Switzerland in late adolescence.</p><p><strong>Conclusions: </strong>This study reveals significant sex disparity in tuberculosis incidence in a country with low tuberculosis incidence, with males showing higher rates than females beginning in late adolescence. This discrepancy is likely influenced by the higher influx of male asylum seekers in adolescence.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4187"},"PeriodicalIF":1.9,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Economic evaluations of antibiotic stewardship programmes 2015-2024: a systematic review. 2015-2024年抗生素管理规划的经济评价:系统综述
IF 2.1 4区 医学
Swiss medical weekly Pub Date : 2025-05-28 DOI: 10.57187/s.4217
Jasmin Huser, Tamara Dörr, Alisa Berger, Philipp Kohler, Stefan P Kuster
{"title":"Economic evaluations of antibiotic stewardship programmes 2015-2024: a systematic review.","authors":"Jasmin Huser, Tamara Dörr, Alisa Berger, Philipp Kohler, Stefan P Kuster","doi":"10.57187/s.4217","DOIUrl":"10.57187/s.4217","url":null,"abstract":"<p><strong>Background: </strong>Numerous studies have demonstrated the effectiveness of Antibiotic Stewardship Programmes in reducing antibiotic resistance and healthcare costs. However, the use of different methods to assess these costs, along with the uncertainty regarding which interventions are cost-effective, hampers the comparison of results and the formulation of clear recommendations. The aim of this systematic review was to provide a comprehensive overview of the available evidence on economic evaluations of Antibiotic Stewardship Programmes and to assess their impact on healthcare costs.</p><p><strong>Methods: </strong>The systematic review analysed articles indexed in Medline, Embase, Cochrane Reviews and Trials, Business Source Premier or EconLit that assessed the attributed economic impact of Antibiotic Stewardship Programme interventions in acute care settings and were published between 2015 and 2024. Studies identifying as economic analyses, cost-benefit analyses, cost-effectiveness analyses, cost-consequence analyses, cost analyses or cost-minimisation analyses and that fulfilled the essential parameters required for an economic analysis were included. A descriptive analysis was conducted to examine the impact of the interventions on overall costs, length of stay and antimicrobial costs. We also analysed the different kinds of interventions and the type of costs considered in the analyses. Study quality was evaluated using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist, version 2022.</p><p><strong>Results: </strong>A total of 2965 publications were identified, of which 411 underwent full-text screening. The 27 studies ultimately included involved 20,232 patients in total and consistently demonstrated savings in antibiotic costs ranging from 2% to 95% relative cost savings, in length of stay costs (3% to 85%) and in overall hospital costs (3% to 86%). The intervention most frequently implemented was \"therapy evaluation, review and/or feedback\" (23/27, 85%), followed by \"alteration of therapy guidelines\" (8/27, 30%) and \"education\" (6/27, 22%). While operational costs were reported by all studies, implementation costs (8/27, 30%) and societal costs (3/27, 11%) were less frequently analysed. By CHEERS category, 9 (33%) of the included studies were rated as low-quality (<60%), 16 (59%) as medium-quality (60-80%) and 2 (7%) as high-quality (>80%).</p><p><strong>Conclusions: </strong>Our results emphasise that Antibiotic Stewardship Programmes may contribute to a substantial reduction in healthcare costs for a hospital. While the economic reporting in the field has recently improved, certain cost categories should be accounted for more consistently. There remains considerable potential for further improvement and standardisation to enhance the comparability of studies and facilitate the implementation of effective Antibiotic Stewardship Programmes.</p>","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4217"},"PeriodicalIF":2.1,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Suplementum 287: Abstracts of the of the joint annual meeting of the Swiss Society of Cardiology and the Swiss Society of Cardiac Surgery (Zurich, Switzerland, June 4-6, 2025). 补编287:瑞士心脏病学会和瑞士心脏外科学会联合年会摘要(苏黎世,瑞士,2025年6月4-6日)。
IF 2.1 4区 医学
Swiss medical weekly Pub Date : 2025-05-28 DOI: 10.57187/s.4706
Swiss Society Of Cardiology, Swiss Society Of Cardiac Surgery
{"title":"Suplementum 287: Abstracts of the of the joint annual meeting of the Swiss Society of Cardiology and the Swiss Society of Cardiac Surgery (Zurich, Switzerland, June 4-6, 2025).","authors":"Swiss Society Of Cardiology, Swiss Society Of Cardiac Surgery","doi":"10.57187/s.4706","DOIUrl":"https://doi.org/10.57187/s.4706","url":null,"abstract":"","PeriodicalId":22111,"journal":{"name":"Swiss medical weekly","volume":"155 ","pages":"4706"},"PeriodicalIF":2.1,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of chronic alcohol use disorder and alcohol withdrawal on phosphate, magnesium, and calcium. 慢性酒精使用障碍和酒精戒断对磷酸盐、镁和钙的影响。
IF 1.9 4区 医学
Swiss medical weekly Pub Date : 2025-05-27 DOI: 10.57187/s.4072
Damiano Bianda, Lars C. Huber, Johannes Trachsler, Mattia Arrigo
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