Sultan Qaboos University Medical Journal最新文献_第5页

Disconnected Pancreatic Duct Syndrome in Complicated Necrotising Pancreatitis. 并发坏死性胰腺炎的胰管断开综合征。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/2075-0528.2825

Nasiba Al Maqrashi, Noor Al Wahaibi, Salim Al Busaidi, Abdullah Al Alawi

引用次数: 0

Endobronchial Metastasis with Extension to the Left Atrium from Adenocarcinoma of Gastric 3 Years after Total Gastrectomy. 全胃切除术后3年胃腺癌支气管内转移并向左心房转移。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/squmj.10.2024.066

Behnam Shakerian, Mohammad H Mandegar

引用次数: 0

Bullous Diabeticorum.

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/2075-0528.2860

Maisam Alsalmani, Ayida Al Khalili, Maiya Al Bahri

引用次数: 0

Pneumocephalus After Mediastinal Surgery. 纵隔手术后的脑气。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/2075-0528.2854

Mohamed Bhairis, Massine El Hammoumi, El Hassane Kabiri

引用次数: 0

Generative Artificial Intelligence in Academic Publishing: A catalyst for transformation or a facilitator for further north-south divide? 学术出版中的生成式人工智能：是转型的催化剂还是南北鸿沟的推动者？

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2898

Samir Al-Adawi, Madan M Maddali

引用次数: 0

Causes of Mortality in Patients with Inborn Errors of Immunity: An 18-year retrospective cohort study. 先天性免疫缺陷患者的死亡原因：一项18年回顾性队列研究

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2896

Salem Al-Tamemi, Musab Al Jabri, Eiman Abdalla, Ibrahim Al-Busaidi, Khalfan Al-Zeedy, Laila Al Yazidi

{"title":"Causes of Mortality in Patients with Inborn Errors of Immunity: An 18-year retrospective cohort study.","authors":"Salem Al-Tamemi, Musab Al Jabri, Eiman Abdalla, Ibrahim Al-Busaidi, Khalfan Al-Zeedy, Laila Al Yazidi","doi":"10.18295/2075-0528.2896","DOIUrl":"10.18295/2075-0528.2896","url":null,"abstract":"Objectives: Inborn errors of immunity (IEI) are a diverse group of disorders arising from defects in the development and/or function of the immune system. However, data concerning the microbiological aspects of infections and direct causes of mortality in patients with IEI are limited and fragmented. This study aimed to elucidate the causes of disease and terminal events leading to death in a cohort of patients with IEI.Methods: This retrospective study included deceased patients who were diagnosed with primary immunodeficiency at Sultan Qaboos University Hospital in Muscat, Oman, over an 18-year period between 2005 and 2023. Data on clinical features, infections, isolated microorganisms and terminal events leading to death were collected and analyzed.Results: A total of 53 cases were included in this study. The mean age at death was 9.1 ± 10.4 years (median: 3.9 years, interquartile range: 15.2 years, range: 0.2-45.2 years). Prior to death, the most frequently isolated microorganisms included Pseudomonas spp. (41.5%), Pseudomonas aeruginosa (34%), Candida spp. (28.3%), cytomegalovirus (26.4%) and Hemophilus influenzae (20.8%), among others. The predominant terminal events leading to death were septicemia/septic shock (64.2%), pneumonia/adult respiratory distress syndrome/multiorgan dysfunction syndrome (49.1%), disseminated viral disease (22.6%) and bronchiectasis/pulmonary hypertension/haemorrhage (20.8%).Conclusion: Understanding factors contributing to terminal events in IEI patients can inform early intervention strategies and potentially reduce mortality rates.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"689-696"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Prevalence and Correlates of Aberrant Opioid-Related Behaviours among Patients with Sickle Cell Disease in Oman: A cross-sectional study. 阿曼镰状细胞病患者中阿片类药物相关异常行为的流行及其相关因素：一项横断面研究

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2888

Abdullah Al Abulsalam, Khawla Al Kindi, Abdullah Al Ghailani, Hamed Al Sinawi, Naser Al Balushi, Salam Al Kindi, Sathiya P Murthi, Amal Al Fahdi, Mohammed Al Alawi

{"title":"The Prevalence and Correlates of Aberrant Opioid-Related Behaviours among Patients with Sickle Cell Disease in Oman: A cross-sectional study.","authors":"Abdullah Al Abulsalam, Khawla Al Kindi, Abdullah Al Ghailani, Hamed Al Sinawi, Naser Al Balushi, Salam Al Kindi, Sathiya P Murthi, Amal Al Fahdi, Mohammed Al Alawi","doi":"10.18295/2075-0528.2888","DOIUrl":"10.18295/2075-0528.2888","url":null,"abstract":"Objectives: This study aimed to assess the prevalence of aberrant opioid-related behaviours (AORB) among patients with sickle cell disease (SCD) in Oman and identify associated risk factors.Methods: This cross-sectional analytical study was conducted at Sultan Qaboos University Hospital, Muscat, Oman from June to December 2022. Patients with SCD aging 18-65 years old were included and clinically observed for more than 3 months. The Current Opioid Misuse Measure (COMM) was used to evaluate AORB with scores of ≥9 indicating high risk. Demographic and clinical data were collected. The association between AORB and clinical-demographic variables was examined using the Chi-square test.Results: A total of 144 SCD patients were included in this study; 58.3% of the participants were at high risk of AORB with a mean COMM score of 12.08. A significant relationship was found between perceived lack of family social support and AORB (P <0.001). No significant associations were observed between AORB risk and other studied factors.Conclusion: This study was the first to document a high prevalence of AORB among SCD patients in Oman. The findings underscore the critical role of family support in mitigating this risk of opioid misuse among this vulnerable population.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"674-680"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Leopard Spot Technique Acupuncture for Shoulder Impingement with Myofascial Pain Syndrome. 豹纹针刺法治疗肩撞击伴肌筋膜疼痛综合征的作用。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/2075-0528.2903

Dewi Ratnasari, Sri Wahdini

引用次数: 0

Effectiveness and Safety Profile of Fingolimod in Treating Omani Patients with Multiple Sclerosis: A single tertiary centre experience. 芬戈莫德治疗阿曼多发性硬化症患者的有效性和安全性：单一三级中心经验。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/2075-0528.2829

Ghaida K H Al-Hashmi, Abdullah Al-Asmi, M Mazharul Islam, Ibrahim Al-Zakwani, Mehwish Butt, Ahmed Al-Qassabi, Haifa Al-Abri, Arunodaya R Gujjar

{"title":"Effectiveness and Safety Profile of Fingolimod in Treating Omani Patients with Multiple Sclerosis: A single tertiary centre experience.","authors":"Ghaida K H Al-Hashmi, Abdullah Al-Asmi, M Mazharul Islam, Ibrahim Al-Zakwani, Mehwish Butt, Ahmed Al-Qassabi, Haifa Al-Abri, Arunodaya R Gujjar","doi":"10.18295/2075-0528.2829","DOIUrl":"10.18295/2075-0528.2829","url":null,"abstract":"Objectives: This study aimed to evaluate the effectiveness and safety of fingolimod in Omani multiple sclerosis (MS) patients. Fingolimod is one of the oral drugs used to treat MS. However, there is limited information on its effectiveness and safety among the Omani population.Methods: This retrospective real-world study included 65 Omani MS patients who received fingolimod therapy from 2012 to 2021 at a single tertiary centre in Oman. Data were collected between August and November 2021. Various measures were used to evaluate the effectiveness and safety of fingolimod.Results: Out of 65 MS patients included in the study, 51 (79%) were female. The median duration of fingolimod use was 3.6 ± 2.5 years. The results of the last follow-up visit indicate that the median annualised relapse rate decreased by 84% and relapse-free rate (RFR) increased to 90%, with only a minimal (13%) increase in the expanded disability status. The median number of gadolinium-enhanced lesions in the brain and spine decreased significantly by 88% and 67%, respectively, while the new or enlarged T2 lesions in the brain significantly decreased by 62% (P < 0.050) over the treatment period. The most common side effect was bradycardia (32%). Patient age and age at treatment initiation were significant predictors of RFR (P < 0.050).Conclusion: This study suggests that the effectiveness and safety profiles of fingolimod in Omani MS patients are similar to those determined by standard clinical trials and real-world retrospective studies.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"225-232"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibiotic Use by Paediatric Residents of the Oman Medical Specialty Board: Identifying opportunities for antimicrobial stewardship. 阿曼医学专业委员会儿科居民使用抗生素：确定抗菌剂管理的机会。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/2075-0528.2861

Shaima Alshukaili, Hussain Al-Saffar, Hatem Al-Rawahi, Laila Al Yazidi

{"title":"Antibiotic Use by Paediatric Residents of the Oman Medical Specialty Board: Identifying opportunities for antimicrobial stewardship.","authors":"Shaima Alshukaili, Hussain Al-Saffar, Hatem Al-Rawahi, Laila Al Yazidi","doi":"10.18295/2075-0528.2861","DOIUrl":"10.18295/2075-0528.2861","url":null,"abstract":"Objectives: This study aimed to evaluate antibiotic prescription knowledge and practices among Oman Medical Specialty Board (OMSB) paediatric residents. The goal was to identify educational opportunities to reduce antimicrobial resistance and improve patient care.Methods: A survey-based cross-sectional study was conducted among the OMSB paediatric residents from August 2023 to September 2023. The online survey involved three parts: residents' demographics, knowledge of 12 common paediatric infection scenarios and clinical practice. Participants were asked to choose the proper antibiotic choices and duration for each scenario. Data analysis was performed using SPSS.Results: A total of 74 responses were obtained, resulting in an 84% response rate. No significant differences were observed in the knowledge of antibiotic prescriptions among paediatric residents at different stages of their residency. The highest knowledge-based adherence rate to local antibiotic guidelines was noted in the acute sinusitis scenario (n = 70; 94.6%), followed by the acute meningitis scenario (n = 68; 91.9%). Conversely, the lowest adherence was observed in the acute otitis media (n = 16; 21.6%), followed by cellulitis (n = 23; 31.1%). Residents exhibited proficient clinical judgement by consulting infectious disease specialists when required based on the scenarios provided.Conclusions: The low knowledge-based adherence to antibiotic guidelines for common paediatric infections, coupled with the lack of significant differences in antibiotic knowledge between senior and junior paediatric residents, underscores the need for collective educational interventions. These interventions aim to advance knowledge and skills in antimicrobial stewardship and local antibiotic guidelines application.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"474-484"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0